Manuel A. Rivas

Biochemistry, Genetics and Molecular Biology

Pilot corpus only

This score is computed over theSindex pilot corpus and does not cover the full scientific literature. Scores are relative to papers we have ingested — papers, authors, and institutions outside the pilot are not represented. Methodology.

Top 1%percentile

32.0Author DataRank

Indexed papers

9in pilot corpus

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Why this DataRank?

An author's DataRank is the sum of the DataRanks of all 9 indexed papers attributed to them. A prolific author with many moderate-impact papers can outrank one with a single high-impact paper.

Author scores recompute whenever paper DataRanks are refreshed, so this number lags the underlying paper scores by at most one batch run.

Read the full methodology →

The highest-impact dataset this researcher has shared, ranked by DataRank — the single contribution doing the most to lift their data-sharing standing.

Analysis of protein-coding genetic variation in 60,706 humans

Nature(2016)10.1038/nature19057

Top 1%

13.0DataRank

Top 1%10410 citations

Monkol Lek, Konrad J. Karczewski, Eric V. Minikel, Kaitlin E. Samocha, Iain Mathieson +76 more

Papers

Driven by 68 papers — median percentile 91. Top paper: “Analysis of protein-coding genetic variation in 60,706 humans”.

Analysis of protein-coding genetic variation in 60,706 humans

Nature(2016)10.1038/nature19057

Top 1%

13.0DataRank

Top 1%10410 citations

Monkol Lek, Konrad J. Karczewski, Eric V. Minikel, Kaitlin E. Samocha, Iain Mathieson +76 more

Correction: Corrigendum: Synchronized age-related gene expression changes across multiple tissues in human and the link to complex diseases

Scientific Reports(2016)10.1038/srep19384

N/A

10.4DataRank · unranked

722 citations

Tao Huang, Francesca Petralia, Quan Long, Bin Zhang, Carmen Argmann +129 more

A map of human genome variation from population-scale sequencing

Nature(2010)10.1038/nature09534

Top 2%

9.1DataRank

Top 2%8109 citations

Min Hu, Yuan Chen, Matthew N. Bainbridge, Richard M. Durbin, Si Quang Le +319 more

Race, socioeconomic deprivation, and hospitalization for COVID-19 in English participants of a national biobank

International Journal for Equity in Health(2020)10.1186/s12939-020-01227-y

N/A

8.0DataRank · unranked

147 citations

Manish Paranjpe, Nina P. Kathiresan, Manuel A. Rivas, Amit V. Khera, Aniruddh P. Patel

A structural variation reference for medical and population genetics

Nature(2020)10.1038/s41586-020-2287-8

Top 3%

6.7DataRank

Top 3%1180 citations

Harrison Brand, Konrad J. Karczewski, Xuefang Zhao, Jessica Alföldi, Laurent C. Francioli +201 more

Landscape of multi-nucleotide variants in 125,748 human exomes and 15,708 genomes

Nature Communications(2020)10.1038/s41467-019-12438-5

N/A

5.6DataRank · unranked

143 citations

James Zou, Beryl B. Cummings, Jessica Alföldi, Laurent C. Francioli, Laura D. Gauthier +174 more

Characterising the loss-of-function impact of 5’ untranslated region variants in 15,708 individuals

Nature Communications(2020)10.1038/s41467-019-10717-9

N/A

5.2DataRank · unranked

191 citations

Konrad J. Karczewski, Xiaolei Zhang, Sonia Chothani, Miriam J. Smith, D. Gareth Evans +181 more

The effect of LRRK2 loss-of-function variants in humans

Nature Medicine(2020)10.1038/s41591-020-0893-5

N/A

4.9DataRank · unranked

114 citations

Irina M. Armean, Aaron Kleinman, Jamie L. Marshall, Eric V. Minikel, Julia K. Goodrich +214 more

Sex-specific genetic effects across biomarkers

European Journal of Human Genetics(2020)10.1038/s41431-020-00712-w

N/A

2.7DataRank · unranked

108 citations

Yosuke Tanigawa, Fátima Rodríguez, Russ B. Altman, Nicholas A. Sinnott-Armstrong, Manuel A. Rivas +1 more

An open resource of structural variation for medical and population genetics

bioRxiv (Cold Spring Harbor Laboratory)(2019)10.1101/578674

Top 9%

2.2DataRank

Top 9%44 citations

Harrison Brand, Konrad J. Karczewski, Xuefang Zhao, Jessica Alföldi, Laurent C. Francioli +37 more

Rare protein-altering variants in ANGPTL7 lower intraocular pressure and protect against glaucoma

PLoS Genetics(2020)10.1371/journal.pgen.1008682

N/A

1.7DataRank · unranked

53 citations

Michael Wainberg, Juha Karjalainen, Tuomo Kiiskinen, Guhan Venkataraman, Susanna Lemmelä +9 more

Landscape of X chromosome inactivation across human tissues

bioRxiv (Cold Spring Harbor Laboratory)(2016)10.1101/073957

N/A

1.6DataRank · unranked

52 citations

Angela Yen, Manuel A. Rivas, Jamie L. Marshall, Rahul Satija, Laura Gauthier +17 more

The mutational constraint spectrum quantified from variation in 141,456 humans

Nature(2020)10.1038/s41586-020-2308-7

N/A

1.4DataRank · unranked

9958 citations

Laurent C. Francioli, Grace Tiao, Beryl B. Cummings, Jessica Alföldi, Qingbo S. Wang +187 more

Evaluating the contribution of rare variants to type 2 diabetes and related traits using pedigrees

Proceedings of the National Academy of Sciences(2017)10.1073/pnas.1705859115

N/A

1.2DataRank · unranked

36 citations

Alisa Manning, Marcio Almeida, Matthew Zawistowski, Katharina Domschke, Tanya M. Teslovich +82 more

A Fast and Scalable Framework for Large-scale and Ultrahigh-dimensional Sparse Regression with Application to the UK Biobank

10.1101/630079

N/A

1.1DataRank · unranked

28 citations

Yosuke Tanigawa, Wenfei Du, Matthew Aguirre, Chris Chang, Robert Tibshirani +3 more

The genetic architecture of type 2 diabetes

Nature(2016)10.1038/nature18642

N/A

1.1DataRank · unranked

1106 citations

Menachem Fromer, Tanya M. Teslovich, Anubha Mahajan, Vineeta Agarwala, Kyle J. Gaulton +334 more

Genetics of 35 blood and urine biomarkers in the UK Biobank

Nature Genetics(2021)10.1038/s41588-020-00757-z

N/A

1.0DataRank · unranked

806 citations

Yosuke Tanigawa, David Amar, Nina Mars, Christian Benner, Matthew Aguirre +19 more

Erratum: Corrigendum: Landscape of X chromosome inactivation across human tissues

Nature(2018)10.1038/nature25993

N/A

0.905DataRank · unranked

15 citations

Angela Yen, Manuel A. Rivas, Jamie L. Marshall, Rahul Satija, Laura Gauthier +17 more

Effect of predicted protein-truncating genetic variants on the human transcriptome

Science(2015)10.1126/science.1261877

N/A

0.877DataRank · unranked

345 citations

Matti Pirinen, Donald F. Conrad, Monkol Lek, Emily K. Tsang, Konrad J. Karczewski +206 more

Graphical analysis for phenome-wide causal discovery in genotyped population-scale biobanks

Nature Communications(2021)10.1038/s41467-020-20516-2

N/A

0.870DataRank · unranked

24 citations

Nicholas A. Sinnott-Armstrong, Euan A. Ashley, Manuel A. Rivas, David Amar

Significant Sparse Polygenic Risk Scores across 813 traits in UK Biobank

medRxiv(2021)10.1101/2021.09.02.21262942

N/A

0.815DataRank · unranked

15 citations

Junyang Qian, Guhan Venkataraman, Johanne Marie Justesen, Ruilin Li, Robert Tibshirani +3 more

Synchronized age-related gene expression changes across multiple tissues in human and the link to complex diseases

Scientific Reports(2015)10.1038/srep15145

N/A

0.811DataRank · unranked

222 citations

Tao Huang, Francesca Petralia, Quan Long, Bin Zhang, Carmen Argmann +128 more

High-throughput SARS-CoV-2 and host genome sequencing from single nasopharyngeal swabs

medRxiv(2020)10.1101/2020.07.27.20163147

Top 25%

0.801DataRank

Top 25%9 citations

Hannah N. De Jong, David Amar, Craig D. Hughes, Alexander G. Ioannidis, Rob Bierman +37 more

Transcript expression-aware annotation improves rare variant interpretation

Nature(2020)10.1038/s41586-020-2329-2

N/A

0.796DataRank · unranked

201 citations

Konrad J. Karczewski, Ditte Demontis, Eleanor G. Seaby, Nicholas A. Watts, Moriel Singer-Berk +177 more

Evaluating drug targets through human loss-of-function genetic variation

Nature(2020)10.1038/s41586-020-2267-z

N/A

0.779DataRank · unranked

179 citations

Konrad J. Karczewski, Hilary C. Martin, Beryl B. Cummings, Nicola Whiffin, Daniel R. Rhodes +150 more

Significant sparse polygenic risk scores across 813 traits in UK Biobank

PLoS Genetics(2022)10.1371/journal.pgen.1010105

N/A

0.770DataRank · unranked

169 citations

Junyang Qian, Guhan Venkataraman, Johanne Marie Justesen, Ruilin Li, Robert Tibshirani +3 more

A fast and scalable framework for large-scale and ultrahigh-dimensional sparse regression with application to the UK Biobank

PLoS Genetics(2020)10.1371/journal.pgen.1009141

N/A

0.736DataRank · unranked

134 citations

Yosuke Tanigawa, Wenfei Du, Matthew Aguirre, Christopher Chang, Robert Tibshirani +3 more

Cannabinoid receptor 1 antagonist genistein attenuates marijuana-induced vascular inflammation

Cell(2022)10.1016/j.cell.2022.04.005

N/A

0.732DataRank · unranked

131 citations

Mark Chandy, Masataka Nishiga, Angela Zhang, Kaavya Krishna Kumar, Dilip Thomas +20 more

Time trajectories in the transcriptomic response to exercise - a meta-analysis

Nature Communications(2021)10.1038/s41467-021-23579-x

N/A

0.719DataRank · unranked

120 citations

Maléne E. Lindholm, Jessica Norrbom, Matthew T. Wheeler, Manuel A. Rivas, Euan A. Ashley +1 more

Quantifying the Impact of Rare and Ultra-rare Coding Variation across the Phenotypic Spectrum

The American Journal of Human Genetics(2018)10.1016/j.ajhg.2018.05.002

N/A

0.713DataRank · unranked

115 citations

F. Kyle Satterstrom, Seyedeh M. Zekavat, Indraniel Das, Mitja I Kurki, Claire Churchhouse +45 more

Author Correction: Genetics of 35 blood and urine biomarkers in the UK Biobank

Nature Genetics(2021)10.1038/s41588-021-00956-2

N/A

0.693DataRank · unranked

14 citations

Yosuke Tanigawa, David Amar, Nina Mars, Christian Benner, Matthew Aguirre +19 more

Evidence of a causal effect of genetic tendency to gain muscle mass on uterine leiomyomata

Nature Communications(2023)10.1038/s41467-023-35974-7

N/A

0.680DataRank · unranked

22 citations

Jaakko Tyrmi, Nilüfer Rahmioğlu, Krina T. Zondervan, Christian M. Becker, FinnGen +95 more

Assessing Digital Phenotyping to Enhance Genetic Studies of Human Diseases

The American Journal of Human Genetics(2020)10.1016/j.ajhg.2020.03.007

N/A

0.628DataRank · unranked

65 citations

Yosuke Tanigawa, Matthew Aguirre, Gregory McInnes, Adam Lavertu, Manuel A. Rivas +1 more

Whole exome sequencing analyses reveal gene–microbiota interactions in the context of IBD

Gut(2020)10.1136/gutjnl-2019-319706

N/A

0.604DataRank · unranked

55 citations

Arnau Vich Vila, Ranko Gaćeša, Valerie Collij, Christine Stevens, Jack Fu +17 more

FasTag: Automatic text classification of unstructured medical narratives

PLoS ONE(2020)10.1371/journal.pone.0234647

N/A

0.578DataRank · unranked

46 citations

Arturo López Pineda, Oliver J. Bear Don’t Walk, Ashley Zehnder, Sandeep Ayyar, Rodney L. Page +3 more

APOC3 genetic variation, serum triglycerides, and risk of coronary artery disease in Asian Indians, Europeans, and other ethnic groups

Lipids in Health and Disease(2021)10.1186/s12944-021-01531-8

N/A

0.557DataRank · unranked

40 citations

Yosuke Tanigawa, Weihua Zhang, Jin Fang Chai, Marcio Almeida, Xueling Sim +29 more

Fast Lasso method for large-scale and ultrahigh-dimensional Cox model with applications to UK Biobank

Biostatistics(2020)10.1093/biostatistics/kxaa038

N/A

0.546DataRank · unranked

37 citations

Christopher Chang, Johanne Marie Justesen, Yosuke Tanigawa, Junyang Qian, Trevor Hastie +3 more

Opportunities and challenges for the use of common controls in sequencing studies

Nature Reviews Genetics(2022)10.1038/s41576-022-00487-4

N/A

0.524DataRank · unranked

32 citations

Jessica Murphy, Jacob Edelson, Christopher R. Gignoux, Alexander G. Ioannidis, Alisa K. Manning +4 more

Integration of rare expression outlier-associated variants improves polygenic risk prediction

The American Journal of Human Genetics(2022)10.1016/j.ajhg.2022.04.015

N/A

0.524DataRank · unranked

32 citations

Nicole M. Ferraro, Qin Hui, Matthew G. Durrant, Matthew Aguirre, Yosuke Tanigawa +14 more

GWAS of three molecular traits highlights core genes and pathways alongside a highly polygenic background

bioRxiv (Cold Spring Harbor Laboratory)(2020)10.1101/2020.04.20.051631

N/A

0.483DataRank · unranked

24 citations

Sahin Naqvi, Manuel A. Rivas, Jonathan K. Pritchard, Nicholas A. Sinnott-Armstrong

Polygenic risk modeling with latent trait-related genetic components

European Journal of Human Genetics(2021)10.1038/s41431-021-00813-0

N/A

0.442DataRank · unranked

18 citations

Yosuke Tanigawa, Guhan Venkataraman, Rob Tibshirani, Trevor Hastie, Manuel A. Rivas +1 more

Pervasive additive and non-additive effects within the HLA region contribute to disease risk in the UK Biobank

bioRxiv (Cold Spring Harbor Laboratory)(2020)10.1101/2020.05.28.119669

N/A

0.425DataRank · unranked

16 citations

Julia Olivieri, Christopher DeBoever, Yosuke Tanigawa, Johanne Marie Justesen, Alexander T Dilthey +2 more

A phenome-wide association study of 26 mendelian genes reveals phenotypic expressivity of common and rare variants within the general population

PLoS Genetics(2020)10.1371/journal.pgen.1008802

N/A

0.416DataRank · unranked

15 citations

Matthew Aguirre, Stefan Gustafsson, Priyanka Saha, Praneetha Potiny, Melissa A Haendel +4 more

Survival analysis on rare events using group-regularized multi-response Cox regression

Bioinformatics(2021)10.1093/bioinformatics/btab095

N/A

0.373DataRank · unranked

11 citations

Yosuke Tanigawa, Johanne Marie Justesen, Jonathan Taylor, Trevor Hastie, Robert Tibshirani +2 more

Bayesian model comparison for rare-variant association studies

The American Journal of Human Genetics(2021)10.1016/j.ajhg.2021.11.005

N/A

0.360DataRank · unranked

10 citations

Christopher DeBoever, Yosuke Tanigawa, Matthew Aguirre, Alexander Ioannidis, Hakhamanesh Mostafavi +7 more

LPA and APOE are associated with statin selection in the UK Biobank

bioRxiv (Cold Spring Harbor Laboratory)(2020)10.1101/2020.08.28.272765

N/A

0.345DataRank · unranked

9 citations

Gregory McInnes, Yosuke Tanigawa, Russ B. Altman, Manuel A. Rivas, Adam Lavertu

Deconvoluting complex correlates of COVID-19 severity with a multi-omic pandemic tracking strategy

Nature Communications(2022)10.1038/s41467-022-32397-8

N/A

0.345DataRank · unranked

9 citations

Alexander G. Ioannidis, David Jimenez‐Morales, John E. Gorzynski, Hannah N. De Jong, Xiran Liu +65 more

High heritability of ascending aortic diameter and multi-ethnic prediction of thoracic aortic disease.

medRxiv(2020)10.1101/2020.05.29.20102335

N/A

0.345DataRank · unranked

9 citations

Ke Xiao, Heliodoro Tejeda, Julie A. Lynch, Sanni Ruotsalainen, Tiffany R. Bellomo +17 more

Integration of rare large-effect expression variants improves polygenic risk prediction

medRxiv(2020)10.1101/2020.12.02.20242990

N/A

0.241DataRank · unranked

4 citations

Nicole M. Ferraro, Matthew G. Durrant, Abhiram Rao, Matthew Aguirre, Xin Li +12 more

Survival Analysis on Rare Events Using Group-Regularized Multi-Response Cox Regression

bioRxiv (Cold Spring Harbor Laboratory)(2020)10.1101/2020.06.21.163675

N/A

0.233DataRank · unranked

3 citations

Yosuke Tanigawa, Johanne Marie Justesen, Jonathan Taylor, Trevor Hastie, Robert Tibshirani +2 more

Efficient storage and regression computation for population-scale genome sequencing studies

Bioinformatics(2025)10.1093/bioinformatics/btaf067

N/A

0.208DataRank · unranked

3 citations

Christopher Chang, Manuel A. Rivas

Cardiac imaging of aortic valve area from 26,142 UK Biobank participants reveal novel genetic associations and shared genetic comorbidity with multiple disease phenotypes

medRxiv(2020)10.1101/2020.04.09.20060012

N/A

0.208DataRank · unranked

3 citations

Catherine Tcheandjieu, Jason Fries, Paroma Varma, Vincent S. Chen, Madalina Fiterau +11 more

Corrigendum to: Fast Lasso method for large-scale and ultrahigh-dimensional Cox model with applications to UK Biobank

Biostatistics(2021)10.1093/biostatistics/kxab019

N/A

0.200DataRank · unranked

2 citations

Christopher Chang, Johanne Marie Justesen, Yosuke Tanigawa, Junyang Qian, Trevor Hastie +3 more

Smiles2Dock: an open large-scale multi-task dataset for ML-based molecular docking

arXiv (Cornell University)(2024)10.48550/arxiv.2406.05738

Top 70%

0.165DataRank

Top 70%2 citations

Manuel A. Rivas, Thomas Le Menestrel

Pretraining and the lasso

Journal of the Royal Statistical Society Series B (Statistical Methodology)(2025)10.1093/jrsssb/qkaf050

N/A

0.165DataRank · unranked

2 citations

Mert Pilancı, Thomas Le Menestrel, Balasubramanian Narasimhan, Manuel A. Rivas, Stein‐Erik Gullaksen +5 more

Genetics of cardiometabolic disease progression

medRxiv(2025)10.1101/2025.02.01.25321518

N/A

0.114DataRank · unranked

1 citations

Guhan Venkataraman, Yosuke Tanigawa, Ruilin Li, Trevor Hastie, Robert Tibshirani +3 more

The Genotype-Tissue Expression (GTEx) pilot analysis: Multitissue gene regulation in humans

UNC Libraries(2020)10.17615/3we9-ae42

Top 100%

0DataRank

Top 100%0 citations

David S. DeLuca, Ayellet V. Segrè, Timothy J. Sullivan, Timothy R. Young, Ellen T. Gelfand +27 more

Fast numerical optimization for genome sequencing data in population biobanks

Bioinformatics(2021)10.1093/bioinformatics/btab452

N/A

0DataRank · unranked

22 citations

Christopher Chang, Yosuke Tanigawa, Balasubramanian Narasimhan, Trevor Hastie, Robert Tibshirani +2 more

Nonsense-mediated decay is highly stable across individuals and tissues

bioRxiv (Cold Spring Harbor Laboratory)(2021)10.1101/2021.02.03.429654

N/A

0DataRank · unranked

6 citations

Daniel Nachun, Tiffany Y. Eulalio, Nicole M. Ferraro, Craig Smail, Manuel A. Rivas +2 more

Whole-Exome Sequencing Identifies Rare and Low-Frequency Coding Variants Associated with LDL Cholesterol

UNC Libraries(2021)10.17615/shbq-nv48

N/A

0DataRank · unranked

0 citations

Douglas M. Ruderfer, Goo Jun, Ji Zhang, Yun Li, Leslie A. Lange +27 more

Combining clinical and polygenic risk improves stroke prediction among individuals with atrial fibrillation

medRxiv(2020)10.1101/2020.06.17.20134163

N/A

0DataRank · unranked

14 citations

Anna Shcherbina, Johanne Marie Justesen, Mintu P. Turakhia, Marco Pérez, Hannah Wand +6 more

Nonsense-mediated decay is highly stable across individuals and tissues

The American Journal of Human Genetics(2021)10.1016/j.ajhg.2021.06.008

N/A

0DataRank · unranked

44 citations

Daniel Nachun, Tiffany Y. Eulalio, Nicole M. Ferraro, Craig Smail, Manuel A. Rivas +2 more

SGLT2 inhibitor ameliorates endothelial dysfunction associated with the commonALDH2alcohol flushing variant

Science Translational Medicine(2023)10.1126/scitranslmed.abp9952

N/A

0DataRank · unranked

52 citations

Xuan Yu, Yu Liu, David T. Paik, Johanne Marie Justesen, Mark Chandy +17 more

Integrative machine learning approaches for predicting disease risk using multi-omics data from the UK Biobank

bioRxiv (Cold Spring Harbor Laboratory)(2024)10.1101/2024.04.16.589819

N/A

0DataRank · unranked

4 citations

Cheng Chang, Elsa Bismuth, Manuel A. Rivas, Oscar Aguilar

Using Pre-training and Interaction Modeling for ancestry-specific disease prediction in UK Biobank

PubMed(2024)10.48550/arxiv.2404.17626

N/A

0DataRank · unranked

2 citations

Erin Craig, Robert Tibshirani, Trevor Hastie, Manuel A. Rivas, Thomas Le Menestrel

A unified meta-regression model identifies genes associated with epilepsy

medRxiv(2024)10.1101/2024.06.27.24309590

N/A

0DataRank · unranked

1 citations

Mijail Rivas, Manuel A. Rivas, Oscar Aguilar

Standardized Measurement of Type 1 Diabetes Polygenic Risk Across Multiancestry Population Cohorts

Diabetes Care(2025)10.2337/dc25-0142

N/A

0DataRank · unranked

14 citations

Richard A. Oram, Aaron J. Deutsch, Héctor Ortega, Diane P. Fraser, Kaavya Ashok +8 more

Using pre-training and interaction modeling for ancestry-specific disease prediction using multiomics data from the UK Biobank

PLoS ONE(2025)10.1371/journal.pone.0336861

N/A

0DataRank · unranked

0 citations

Erin Craig, Robert Tibshirani, Trevor Hastie, Manuel A. Rivas, Thomas Le Menestrel

Manuel A. Rivas

Indexed papers

Top data-sharing exemplar

Papers