Robert J. Lefkowitz

Also affiliated with Duke University, Duke Medical Center, Duke University Hospital

Biochemistry, Genetics and Molecular BiologyNeuroscienceAgricultural and Biological Sciences

Pilot corpus only

This score is computed over theSindex pilot corpus and does not cover the full scientific literature. Scores are relative to papers we have ingested — papers, authors, and institutions outside the pilot are not represented. Methodology.

Top 100%percentile

0Author DataRank

Indexed papers

0in pilot corpus

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Papers

Driven by 24 papers. Top paper: “Molecular mechanism of biased signaling in a prototypical G protein–coupled receptor”.

Molecular mechanism of biased signaling in a prototypical G protein–coupled receptor

Science(2020)10.1126/science.aaz0326

N/A

0.825DataRank · unranked

244 citations

Naomi R. Latorraca, Laura M. Wingler, Stephan Eismann, Matthew C. King, A.L.W. Kleinhenz +6 more

Conformational Basis of G Protein-Coupled Receptor Signaling Versatility

Trends in Cell Biology(2020)10.1016/j.tcb.2020.06.002

N/A

0.817DataRank · unranked

231 citations

Robert J. Lefkowitz, Laura M. Wingler

GPCR-mediated β-arrestin activation deconvoluted with single-molecule precision

Cell(2022)10.1016/j.cell.2022.03.042

N/A

0.708DataRank · unranked

111 citations

Daniel S. Terry, G. Glenn Gregorio, Alem W. Kahsai, Alessandro Borgia, Bing Xie +13 more

Signal transduction at GPCRs: Allosteric activation of the ERK MAPK by β-arrestin

Proceedings of the National Academy of Sciences(2023)10.1073/pnas.2303794120

N/A

0.626DataRank · unranked

64 citations

Kunal S. Shah, Paul J. Shim, Mason Lee, Bowie N. Shreiber, Allison M. Schwalb +7 more

Synthetic nanobodies as angiotensin receptor blockers

Proceedings of the National Academy of Sciences(2020)10.1073/pnas.2009029117

N/A

0.624DataRank · unranked

63 citations

Dean P. Staus, Laura M. Wingler, Jialu Wang, Meredith A. Skiba, Matthias Elgeti +5 more

SnapShot: β-Arrestin Functions

Cell(2020)10.1016/j.cell.2020.07.034

N/A

0.590DataRank · unranked

50 citations

Sudha K. Shenoy, Louis M. Luttrell, Robert J. Lefkowitz, Seungkirl Ahn

Structure and dynamics determine G protein coupling specificity at a class A GPCR

Science Advances(2025)10.1126/sciadv.adq3971

N/A

0.553DataRank · unranked

39 citations

Haoqing Wang, Patrick J. Brennan, Chris Habrian, Harald Hübner, Maximilian F. Schmidt +18 more

Allosteric modulator potentiates β2AR agonist–promoted bronchoprotection in asthma models

Journal of Clinical Investigation(2023)10.1172/jci167337

N/A

0.442DataRank · unranked

18 citations

Harm Maarsingh, Julia K. L. Walker, Samuel Liu, Akhil Hegde, Hyeje C. Sumajit +3 more

β 2 -Adrenergic Receptor Signaling and Desensitization Elucidated by Quantitative Modeling of Real Time cAMP Dynamics

UNC Libraries(2021)10.17615/p52z-gj38

N/A

0DataRank · unranked

0 citations

Jonathan D. Violin, Robert J. Lefkowitz, Lisa M. DiPilato, Necmettin Yıldırım, Jin Zhang +1 more

β-Arrestins Regulate Protease-activated Receptor-1 Desensitization but Not Internalization or Down-regulation

UNC Libraries(2021)10.17615/ymqj-ap31

N/A

0DataRank · unranked

0 citations

Amy B. Stutts, Trudy A. Kohout, Robert J. Lefkowitz, May M. Paing, JoAnn Trejo

Enhanced Rewarding Properties of Morphine, but not Cocaine, in βarrestin-2 Knock-Out Mice

UNC Libraries(2021)10.17615/ygfm-ze71

N/A

0DataRank · unranked

0 citations

Robert J. Lefkowitz, Linda Dykstra, Marc G. Caron, Raul R. Gainetdinov, Tatyana D. Sotnikova +2 more

Loss of Biased Signaling Specificity of the Angiotensin II Type 1 Receptor in Overexpressed Systems

The FASEB Journal(2022)10.1096/fasebj.2022.36.s1.r2797

N/A

0DataRank · unranked

0 citations

Samuel Liu, Rennica Huang, Seungkirl Ahn, Robert J. Lefkowitz, Angus Li

Loss of biased signaling at a G protein-coupled receptor in overexpressed systems

PLoS ONE(2023)10.1371/journal.pone.0283477

N/A

0DataRank · unranked

35 citations

Samuel Liu, Rennica Huang, Seungkirl Ahn, Robert J. Lefkowitz, Angus Li

G protein–coupled receptors: from radioligand binding to cellular signaling

Journal of Clinical Investigation(2024)10.1172/jci178109

N/A

0DataRank · unranked

9 citations

Robert J. Lefkowitz, Howard A. Rockman

Structure and dynamics determine G protein coupling specificity at a class A GPCR

bioRxiv (Cold Spring Harbor Laboratory)(2024)10.1101/2024.03.28.587240

N/A

0DataRank · unranked

7 citations

Haoqing Wang, Patrick J. Brennan, Chris Habrian, Harald Hübner, Maximilian F. Schmidt +14 more

Angiotensin and biased analogs induce structurally distinct active conformations within a GPCR

Science(2020)10.1126/science.aay9813

N/A

0DataRank · unranked

248 citations

Meredith A. Skiba, Conor McMahon, Dean P. Staus, A.L.W. Kleinhenz, Carl‐Mikael Suomivuori +5 more

A positive allosteric modulator of the β1AR with antagonist activity for catecholaminergic polymorphic ventricular tachycardia

Journal of Clinical Investigation(2025)10.1172/jci190252

N/A

0DataRank · unranked

1 citations

Robin M. Perelli, Seungkirl Ahn, Haoran Jiang, Arun Jyothidasan, Damini Sood +12 more

Allosteric activation of proto-oncogene kinase Src by GPCR–beta-arrestin complexes

Journal of Biological Chemistry(2020)10.1074/jbc.ra120.015400

N/A

0DataRank · unranked

50 citations

Ali Masoudi, Biswaranjan Pani, Dean P. Staus, Robert J. Lefkowitz, Natalia Pakharukova

The β-arrestin-biased β-adrenergic receptor blocker carvedilol enhances skeletal muscle contractility

Proceedings of the National Academy of Sciences(2020)10.1073/pnas.1920310117

N/A

0DataRank · unranked

43 citations

Chad A. Grotegut, James W. Wisler, Lan Mao, Paul B. Rosenberg, Howard A. Rockman +2 more

β-Arrestin–Biased Angiotensin II Receptor Agonists for COVID-19

Circulation(2020)10.1161/circulationaha.120.048723

N/A

0DataRank · unranked

24 citations

Laura M. Wingler, Howard A. Rockman, Robert J. Lefkowitz, Aashish Manglik

Allosteric “beta-blocker” isolated from a DNA-encoded small molecule library

UNC Libraries(2020)10.17615/rq3f-tf63

N/A

0DataRank · unranked

0 citations

Biswaranjan Pani, Lillian Sun, Dean P. Staus, Ted Cho, Eva K. Olsen +20 more

Discovery of β2 Adrenergic Receptor Ligands Using Biosensor Fragment Screening of Tagged Wild-Type Receptor

Figshare(2020)10.17615/zms0-t330

N/A

0DataRank · unranked

0 citations

Laura M. Wingler, Seungkirl Ahn, Iva Navrátilová, Zhu Xiao, Kevin D. Read +13 more

The GPCR–β-arrestin complex allosterically activates C-Raf by binding its amino terminus

Journal of Biological Chemistry(2021)10.1016/j.jbc.2021.101369

N/A

0DataRank · unranked

28 citations

Alem W. Kahsai, Natalia Pakharukova, Li-Yin Huang, Robert J. Lefkowitz, Yunxiang Zang

Essential role of beta-adrenergic receptor kinase 1 in cardiac development and function

DukeSpace (Duke University)(2021)10.17615/3t6v-g367

N/A

0DataRank · unranked

14 citations

John Ross, Walter J. Koch, Howard A. Rockman, Bradley D. Smith, Robert J. Lefkowitz +5 more