Charles A. Gersbach

Also affiliated with Genetic Technologies (Australia)

Biochemistry, Genetics and Molecular BiologyMedicine

Pilot corpus only

This score is computed over theSindex pilot corpus and does not cover the full scientific literature. Scores are relative to papers we have ingested — papers, authors, and institutions outside the pilot are not represented. Methodology.

Top 3%percentile

1.2Author DataRank

Indexed papers

4in pilot corpus

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Why this DataRank?

An author's DataRank is the sum of the DataRanks of all 4 indexed papers attributed to them. A prolific author with many moderate-impact papers can outrank one with a single high-impact paper.

Author scores recompute whenever paper DataRanks are refreshed, so this number lags the underlying paper scores by at most one batch run.

Read the full methodology →

The highest-impact dataset this researcher has shared, ranked by DataRank — the single contribution doing the most to lift their data-sharing standing.

Multicenter integrated analysis of noncoding CRISPRi screens

Nature Methods(2024)10.1038/s41592-024-02216-7

Top 20%

1.0DataRank

Top 20%54 citations

Josh Tycko, Jin Woo Oh, Lexi R. Bounds, Sager J. Gosai, Lazaros Lataniotis +29 more

Papers

Driven by 50 papers — median percentile 59. Top paper: “Cas9-specific immune responses compromise local and systemic AAV CRISPR therapy in multiple dystrophic canine models”.

Cas9-specific immune responses compromise local and systemic AAV CRISPR therapy in multiple dystrophic canine models

Nature Communications(2021)10.1038/s41467-021-26830-7

N/A

4.2DataRank · unranked

175 citations

Sandeep Kumar, Dennis O. Pérez‐López, Nalinda B. Wasala, Dong Zhang, Yongping Yue +19 more

Master Regulators and Cofactors of Human Neuronal Cell Fate Specification Identified by CRISPR Gene Activation Screens

Cell Reports(2020)10.1016/j.celrep.2020.108460

N/A

1.9DataRank · unranked

76 citations

Sean R. McCutcheon, Shataakshi Dube, Alejandro Barrera, Tyler S. Klann, Grayson Rice +5 more

Multicenter integrated analysis of noncoding CRISPRi screens

Nature Methods(2024)10.1038/s41592-024-02216-7

Top 20%

1.0DataRank

Top 20%54 citations

Josh Tycko, Jin Woo Oh, Lexi R. Bounds, Sager J. Gosai, Lazaros Lataniotis +29 more

The once and future gene therapy

Nature Communications(2020)10.1038/s41467-020-19505-2

N/A

0.868DataRank · unranked

326 citations

Charles A. Gersbach, Karen Bulaklak

Synthetic biomolecular condensates enhance translation from a target mRNA in living cells

Nature Chemistry(2025)10.1038/s41557-024-01706-7

N/A

0.845DataRank · unranked

41 citations

Sonal Deshpande, Seyed Ali Eghtesadi, Miranda Zhong, Cassio M. Fontes, David N. Fiflis +11 more

The NIH Somatic Cell Genome Editing program

Nature(2021)10.1038/s41586-021-03191-1

N/A

0.736DataRank · unranked

134 citations

Erik J. Sontheimer, Philip J. Brooks, Melinda R. Dwinell, Charles A. Gersbach, David R. Liu +70 more

Engineering Delivery Vehicles for Genome Editing

Annual Review of Chemical and Biomolecular Engineering(2016)10.1146/annurev-chembioeng-080615-034711

N/A

0.716DataRank · unranked

117 citations

Charles A. Gersbach, Christopher E. Nelson

Synthesis of programmable integrases

Proceedings of the National Academy of Sciences(2009)10.1073/pnas.0812502106

N/A

0.680DataRank · unranked

92 citations

Charles A. Gersbach, Carlos F. Barbas, Russell M. Gordley

Transcriptional and epigenetic regulators of human CD8+ T cell function identified through orthogonal CRISPR screens

Nature Genetics(2023)10.1038/s41588-023-01554-0

N/A

0.661DataRank · unranked

81 citations

Adam M. Swartz, Michael C. Brown, Alejandro Barrera, Christian McRoberts Amador, Keith Siklenka +9 more

Immunity to Cas9 as an Obstacle to Persistent Genome Editing

Molecular Therapy(2020)10.1016/j.ymthe.2020.05.007

N/A

0.557DataRank · unranked

40 citations

Charles A. Gersbach, Veronica Gough

Mechanosensitive genomic enhancers potentiate the cellular response to matrix stiffness

Science(2025)10.1126/science.adl1988

N/A

0.533DataRank · unranked

21 citations

Lexi R. Bounds, Carson Key Taylor, Alan L Su, Anthony Rizzo, Alejandro Barrera +12 more

Chromatin Remodeling of Colorectal Cancer Liver Metastasis is Mediated by an HGF‐PU.1‐DPP4 Axis

Advanced Science(2021)10.1002/advs.202004673

N/A

0.533DataRank · unranked

34 citations

Ergang Wang, Jorge Prado Balcazar, Zhenhua Wu, Kun Xiang, Yi Wang +22 more

Proximity analysis of native proteomes reveals phenotypic modifiers in a mouse model of autism and related neurodevelopmental conditions

Nature Communications(2024)10.1038/s41467-024-51037-x

N/A

0.500DataRank · unranked

27 citations

Daichi Shonai, Matthew Trn, Jieqing Zhao, Erik J. Soderblom, S. Alexandra Garcia-Moreno +9 more

Enhancer RNAs predict enhancer-gene regulatory links and are critical for enhancer function in neuronal systems

bioRxiv (Cold Spring Harbor Laboratory)10.1101/270967

N/A

0.444DataRank · unranked

6 citations

Robert A. Phillips, Rhiana C. Simon, Salomon A. Roman Soto, Jenna E. Hinds, Aaron J. Salisbury +8 more

Activation of the imprinted Prader-Willi syndrome locus by CRISPR-based epigenome editing

Cell Genomics(2025)10.1016/j.xgen.2025.100770

N/A

0.434DataRank · unranked

17 citations

Joshua B. Black, Sean R. McCutcheon, Alejandro Barrera, Shanté S. Berry, Daniel J. Morone +7 more

Genome-wide annotation of gene regulatory elements linked to cell fitness

bioRxiv (Cold Spring Harbor Laboratory)(2021)10.1101/2021.03.08.434470

N/A

0.416DataRank · unranked

15 citations

Tyler S. Klann, Alejandro Barrera, Adarsh R. Ettyreddy, Siyan Liu, Ryan Rickels +10 more

Orthogonal CRISPR screens to identify transcriptional and epigenetic regulators of human CD8 T cell function

bioRxiv (Cold Spring Harbor Laboratory)(2023)10.1101/2023.05.01.538906

N/A

0.330DataRank · unranked

8 citations

Adam M. Swartz, Michael C. Brown, Alejandro Barrera, Christian McRoberts Amador, Keith Siklenka +7 more

Characterization and bioinformatic filtering of ambient gRNAs in single-cell CRISPR screens using CLEANSER

Cell Genomics(2025)10.1016/j.xgen.2025.100766

N/A

0.292DataRank · unranked

6 citations

Marisa C. Hamilton, Thomas Cowart, Alejandro Barrera, Lexi R. Bounds, Alexander C. Nelson +8 more

The IGVF catalog—from genetic variation to function

Nucleic Acids Research(2025)10.1093/nar/gkaf1341

Top 63%

0.219DataRank

Top 63%3 citations

Shane Liu, Pedro Assis, Mingjie Li, Shengcheng Dong, Ian Whaling +42 more

Characterization and bioinformatic filtering of ambient gRNAs in single-cell CRISPR screens using CLEANSER

bioRxiv (Cold Spring Harbor Laboratory)(2024)10.1101/2024.09.04.611293

N/A

0.165DataRank · unranked

2 citations

Marisa C. Hamilton, Thomas Cowart, Alejandro Barrera, Lexi R. Bounds, Alexander C. Nelson +6 more

SMARCA2 is an essential and potent cofactor for a specific subset of the glucocorticoid response in A549 cells

bioRxiv (Cold Spring Harbor Laboratory)(2025)10.1101/2025.11.13.688306

N/A

0.104DataRank · unranked

1 citations

D. Dewran Koçak, Keith Siklenka, Graham D. Johnson, Courtney Williams, Luke C. Bartelt +6 more

Deletion of Exon 51 in a Humanized Duchenne Muscular Dystrophy Mouse Model Abolishes Ventricular Arrhythmia Predisposition

Circulation Genomic and Precision Medicine(2025)10.1161/circgen.124.004867

N/A

0.104DataRank · unranked

1 citations

Madeleine J. Sitton, Joel D. Bohning, Adrian Pickar‐Oliver, K. Tyler McCullough, Mary E. Moya‐Mendez +7 more

Functional Annotation of the Major Histocompatibility Complex Locus

bioRxiv (Cold Spring Harbor Laboratory)(2026)10.64898/2026.02.01.703124

N/A

0.104DataRank · unranked

1 citations

Alejandro Barrera, Maria ter Weele, Siyan Liu, Euphy Wu, Shengyu Li +22 more

Respiratory pathology in the mdx/utrn-/- mouse: A murine model for Duchenne Muscular Dystrophy (DMD)

PLoS ONE(2025)10.1371/journal.pone.0316295

N/A

0DataRank · unranked

8 citations

Debolina D. Biswas, Aoife D. Slyne, Jane Lee, Evelyn Scarrow, Sarra M. Abdelbarr +6 more

A gene regulatory element modulates myosin expression and controls cardiomyocyte response to stress

bioRxiv (Cold Spring Harbor Laboratory)(2025)10.1101/2025.07.19.665672

N/A

0DataRank · unranked

0 citations

Irene M. Kaplow, Baekgyu Choi, Enya Dewars, Robin M. Perelli, Kevin Hagy +9 more

A gene regulatory element modulates myosin expression and controls cardiomyocyte response to stress

Genome Research(2025)10.1101/gr.280825.125

N/A

0DataRank · unranked

0 citations

Irene M. Kaplow, Baekgyu Choi, Enya Dewars, Robin M. Perelli, Kevin Hagy +9 more

Circuit-specific gene editing for precision modulation of neuronal activity with CRISPR-rabies virus

bioRxiv (Cold Spring Harbor Laboratory)(2025)10.1101/2025.11.03.686433

N/A

0DataRank · unranked

0 citations

Jing Xu, Elizabeth A. Matthews, Samantha Deasy, Lin He, Diego Fernández Arroyo +9 more

Mechanosensitive genomic enhancers potentiate the cellular response to matrix stiffness

bioRxiv (Cold Spring Harbor Laboratory)(2024)10.1101/2024.01.10.574997

N/A

0DataRank · unranked

6 citations

Lexi R. Bounds, Carson Key Taylor, Alan L Su, Anthony Rizzo, Alejandro Barrera +4 more

Prospective isolation of chondroprogenitors from human iPSCs based on cell surface markers identified using a CRISPR-Cas9-generated reporter

Stem Cell Research & Therapy(2020)10.1186/s13287-020-01597-8

N/A

0DataRank · unranked

69 citations

Chia‐Lung Wu, Nancy Steward, Shaunak Adkar, Charles A. Gersbach, Farshid Guilak +1 more

In Vivo Gene Editing of Muscle Stem Cells with Adeno-Associated Viral Vectors in a Mouse Model of Duchenne Muscular Dystrophy

Molecular Therapy — Methods & Clinical Development(2020)10.1016/j.omtm.2020.09.016

N/A

0DataRank · unranked

58 citations

Adarsh R. Ettyreddy, Ashish Vankara, Joel D. Bohning, Garth Devlin, Stephen D. Hauschka +3 more

Redirecting Vesicular Transport to Improve Nonviral Delivery of Molecular Cargo

Advanced Biosystems(2020)10.1002/adbi.202000059

N/A

0DataRank · unranked

10 citations

Chun‐Chi Chang, Adrian Pickar‐Oliver, Lisa D. Cervia, Liangli Wang, Jing Ji +4 more

Myogenic Progenitor Cell Lineage Specification by CRISPR/Cas9-Based Transcriptional Activators

Stem Cell Reports(2020)10.1016/j.stemcr.2020.03.026

N/A

0DataRank · unranked

25 citations

Ashish Vankara, Adarsh R. Ettyreddy, Joel D. Bohning, Charles A. Gersbach, Jennifer B. Kwon

Transgenic mice for in vivo epigenome editing with CRISPR-based systems

Nature Methods(2021)10.1038/s41592-021-01207-2

N/A

0DataRank · unranked

139 citations

Keith Siklenka, Erica Rodriguez, Katherine R. Tonn Eisinger, Alejandro Barrera, Fang Liu +18 more

Branched-chain α-ketoacids are preferentially reaminated and activate protein synthesis in the heart

Nature Communications(2021)10.1038/s41467-021-21962-2

N/A

0DataRank · unranked

98 citations

Bridgette A. Christopher, Scott B. Crown, Guofang Zhang, Adrian Pickar‐Oliver, Takeshi Yoneshiro +16 more

Full-length dystrophin restoration via targeted exon integration by AAV-CRISPR in a humanized mouse model of Duchenne muscular dystrophy

Molecular Therapy(2021)10.1016/j.ymthe.2021.09.003

N/A

0DataRank · unranked

67 citations

Veronica Gough, Joel D. Bohning, Siyan Liu, Jacqueline N. Robinson-Hamm, Heather Daniels +5 more

Integrating Biomaterials and Genome Editing Approaches to Advance Biomedical Science

Annual Review of Biomedical Engineering(2021)10.1146/annurev-bioeng-122019-121602

N/A

0DataRank · unranked

10 citations

Brian D. Cosgrove, Charles A. Gersbach, Krishanu Saha, Amr A. Abdeen

AP-1 subunits converge promiscuously at enhancers to potentiate transcription

Genome Research(2021)10.1101/gr.267898.120

N/A

0DataRank · unranked

45 citations

D. Dewran Koçak, Luke C. Bartelt, Courtney Williams, Alejandro Barrera, Charles A. Gersbach +2 more

Transgenic mice for in vivo epigenome editing with CRISPR-based systems

bioRxiv (Cold Spring Harbor Laboratory)(2021)10.1101/2021.03.08.434430

N/A

0DataRank · unranked

3 citations

Keith Siklenka, Erica Rodriguez, Katherine R. Tonn Eisinger, Alejandro Barrera, Fang Liu +18 more

Cross-species evolution of a highly potent AAV variant for therapeutic gene transfer and genome editing

Nature Communications(2022)10.1038/s41467-022-33745-4

N/A

0DataRank · unranked

83 citations

Katherine E. Simon, Leo O. Blondel, Marco M. Fanous, Angela L. Roger, Maribel Santiago Maysonet +10 more

Robust, Durable Gene Activation In Vivo via mRNA-Encoded Activators

ACS Nano(2022)10.1021/acsnano.1c10631

N/A

0DataRank · unranked

50 citations

Swapnil Bawage, Nahid Iglesias, Hannah E. Peck, Ryan A. Hobbs, James A. Wroe +4 more

Nonviral In Vivo Delivery of CRISPR-Cas9 Using Protein-Agnostic, High-Loading Porous Silicon and Polymer Nanoparticles

ACS Nano(2023)10.1021/acsnano.2c12261

N/A

0DataRank · unranked

30 citations

Larry D. Stokes, Isom B. Kelly, K. Henderson, Isabel C. Vallecillo-Viejo, Juan M. Colazo +17 more

PCSK9 activation promotes early atherosclerosis in a vascular microphysiological system

APL Bioengineering(2023)10.1063/5.0167440

N/A

0DataRank · unranked

12 citations

Kevin L. Shores, Jason J. Breithaupt, Caleb S. Lee, Daniella M. Fodera, Jennifer B. Kwon +8 more

Epigenome editing technologies for discovery and medicine

Nature Biotechnology(2024)10.1038/s41587-024-02320-1

N/A

0DataRank · unranked

99 citations

Dahlia Rohm, Nahid Iglesias, Charles A. Gersbach, Sean R. McCutcheon

A humanized mouse model for adeno-associated viral gene therapy

Nature Communications(2024)10.1038/s41467-024-46017-0

N/A

0DataRank · unranked

10 citations

Tong Chen, Trevor Gonzalez, Francis P. Pankowicz, Seh Hoon Oh, Helen L. Streff +13 more

Engineered Cas9 variants bypass Keap1-mediated degradation in human cells and enhance epigenome editing efficiency

Nucleic Acids Research(2024)10.1093/nar/gkae761

N/A

0DataRank · unranked

9 citations

Siyuan Su, Adrian Pickar‐Oliver, Anna M. Chiarella, Quentin Hahn, Dennis Goldfarb +9 more

Respiratory characterization of a humanized Duchenne muscular dystrophy mouse model

Respiratory Physiology & Neurobiology(2024)10.1016/j.resp.2024.104282

N/A

0DataRank · unranked

5 citations

Debolina D. Biswas, Meredith L. Huston, Davina Le, Aidan M. Bailey, Logan A. Pucci +5 more

Machine learning methods for predicting guide RNA effects in CRISPR epigenome editing experiments

bioRxiv (Cold Spring Harbor Laboratory)(2024)10.1101/2024.04.18.590188

N/A

0DataRank · unranked

5 citations

Tianyou Luo, Alejandro Barrera, Lexi R. Bounds, Tyler S. Klann, Maria ter Weele +7 more

Activation of the imprinted Prader-Willi Syndrome locus by CRISPR-based epigenome editing

bioRxiv (Cold Spring Harbor Laboratory)(2024)10.1101/2024.03.03.583177

N/A

0DataRank · unranked

3 citations

Joshua B. Black, Sean R. McCutcheon, Alejandro Barrera, Daniel J. Morone, Xander Nuttle +6 more

Gene regulation technologies for gene and cell therapy

Molecular Therapy(2025)10.1016/j.ymthe.2025.04.004

N/A

0DataRank · unranked

30 citations

Samuel Reisman, Nahid Iglesias, Charles A. Gersbach, Gabriel L. Butterfield

Characterization of diverse Cas9 orthologs for genome and epigenome editing

Proceedings of the National Academy of Sciences(2025)10.1073/pnas.2417674122

N/A

0DataRank · unranked

10 citations

Dahlia Rohm, Avery Roberts, Matthew A. Nethery, Anthony Rizzo, Daniel J. Morone +5 more

Charles A. Gersbach

Indexed papers

Top data-sharing exemplar

Papers