Jeffrey G. McDonald

Also affiliated with Hormel (United States), Laboratory of Molecular Genetics, Southwestern Medical Center, Center for Human Genetics, Adelphi Laboratory Center, The University of Texas Southwestern Medical Center

MedicineBiochemistry, Genetics and Molecular Biology

Pilot corpus only

This score is computed over theSindex pilot corpus and does not cover the full scientific literature. Scores are relative to papers we have ingested — papers, authors, and institutions outside the pilot are not represented. Methodology.

Top 100%percentile

0Author DataRank

Indexed papers

0in pilot corpus

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Papers

Driven by 58 papers. Top paper: “Interplay between Asters/GRAMD1s and phosphatidylserine in intermembrane transport of LDL cholesterol”.

Interplay between Asters/GRAMD1s and phosphatidylserine in intermembrane transport of LDL cholesterol

Proceedings of the National Academy of Sciences(2022)10.1073/pnas.2120411119

N/A

1.5DataRank · unranked

43 citations

Michael S. Brown, Joachim Seemann, Gonçalo Vale, Jeffrey G. McDonald, Joseph L. Goldstein +2 more

Last step in the path of LDL cholesterol from lysosome to plasma membrane to ER is governed by phosphatidylserine

Proceedings of the National Academy of Sciences(2020)10.1073/pnas.2010682117

N/A

0.738DataRank · unranked

136 citations

Michael S. Brown, Joseph L. Goldstein, Jaeil Han, Gonçalo Vale, Jeffrey G. McDonald +4 more

Hepatic TM6SF2 Is Required for Lipidation of VLDL in a Pre-Golgi Compartment in Mice and Rats

Cellular and Molecular Gastroenterology and Hepatology(2021)10.1016/j.jcmgh.2021.12.008

N/A

0.705DataRank · unranked

109 citations

Ēriks Šmagris, Sarah A. Martin, Gonçalo Vale, Jeffrey G. McDonald, Justin A. Fletcher +4 more

Cholesterol 25-hydroxylase promotes efferocytosis and resolution of lung inflammation

JCI Insight(2020)10.1172/jci.insight.137189

N/A

0.646DataRank · unranked

73 citations

Eric D. Morrell, Kymberly M. Gowdy, Jeffrey G. McDonald, Bonne M. Thompson, Ginger W. Muse +14 more

A conserved megaprotein-based molecular bridge critical for lipid trafficking and cold resilience

Nature Communications(2022)10.1038/s41467-022-34450-y

N/A

0.561DataRank · unranked

41 citations

Bingying Wang, Taruna Pandey, Yong Long, Jianxiu Zhang, Fiona Oh +13 more

Measurement of lipogenic flux by deuterium resolved mass spectrometry

Nature Communications(2021)10.1038/s41467-021-23958-4

N/A

0.557DataRank · unranked

40 citations

Stanisław Deja, Justin A. Fletcher, Norma N. Anderson, Monika Mizerska, Gonçalo Vale +6 more

Vibrio deploys type 2 secreted lipase to esterify cholesterol with host fatty acids and mediate cell egress

eLife(2020)10.7554/elife.58057

N/A

0.505DataRank · unranked

28 citations

Marcela de Souza Santos, Alexander E. Lafrance, Ann Ray, Wan-Ru Lee, Giomar Rivera‐Cancel +7 more

Statin-mediated reduction in mitochondrial cholesterol primes an anti-inflammatory response in macrophages by upregulating Jmjd3

eLife(2024)10.7554/elife.85964

N/A

0.477DataRank · unranked

11 citations

Kristin Dauner, Yunfeng Li, Neha Verma, David Valdivieso González, Víctor G. Almendro‐Vedia +12 more

Transcriptional Integration of Distinct Microbial and Nutritional Signals by the Small Intestinal Epithelium

Cellular and Molecular Gastroenterology and Hepatology(2022)10.1016/j.jcmgh.2022.04.013

N/A

0.416DataRank · unranked

15 citations

James M. Davison, Cecelia Kelly, Gilberto Padilla Mercado, Jia Wen, Briana R. Davis +7 more

Circulating 27-hydroxycholesterol and Risk of Colorectal Adenomas and Serrated Polyps

Cancer Prevention Research(2021)10.1158/1940-6207.capr-20-0414

N/A

0.373DataRank · unranked

11 citations

Bonne M. Thompson, Jeffrey G. McDonald, Dale C. Snover, Thomas J. Palys, Judy R. Rees +3 more

ZMYND8 drives HER2 antibody resistance in breast cancer via lipid control of IL-27

Nature Communications(2025)10.1038/s41467-025-59184-5

N/A

0.373DataRank · unranked

11 citations

Yijie Wang, Lei Bao, Gonçalo Vale, Jeffrey G. McDonald, Yisheng Fang +9 more

CLSTN3B promotes lipid droplet maturation and lipid storage in mouse adipocytes

Nature Communications(2024)10.1038/s41467-024-53750-z

N/A

0.360DataRank · unranked

10 citations

Mengchen Ye, Kamran Melikov, Dengbao Yang, Gonçalo Vale, Jeffrey G. McDonald +4 more

Regulated adipose tissue-specific expression of human AGPAT2 in lipodystrophic Agpat2-null mice results in regeneration of adipose tissue

iScience(2023)10.1016/j.isci.2023.107806

N/A

0.269DataRank · unranked

5 citations

Katie Tunison, Gonçalo Vale, Jeffrey G. McDonald, Xilong Li, Philipp E. Scherer +3 more

Advanced alcoholic liver disease driven by a proferroptotic diet

Journal of Lipid Research(2025)10.1016/j.jlr.2025.100898

N/A

0.165DataRank · unranked

2 citations

Yanchao Xu, Megan Virostek, Ann L. Johnson, Bret M. Evers, Yaqin Deng +6 more

CLSTN3B enhances adipocyte lipid droplet structure and function via endoplasmic reticulum contact

bioRxiv (Cold Spring Harbor Laboratory)(2024)10.1101/2024.01.20.576491

N/A

0.125DataRank · unranked

1 citations

Mengchen Ye, Kamran Melikov, Dengbao Yang, Gonçalo Vale, Jeffrey G. McDonald +4 more

DHCR24-mediated sterol homeostasis during spermatogenesis is required for sperm mitochondrial sheath formation and impacts male fertility over time

bioRxiv (Cold Spring Harbor Laboratory)(2023)10.1101/2023.12.21.572851

N/A

0.104DataRank · unranked

1 citations

Huafeng Wang, Xinbo Zhang, Pablo Fernández‐Tussy, Kyungjo Jeong, Jungmin Choi +5 more

A Concerted Mechanism Involving ACAT and SREBPs By which Oxysterols Deplete Accessible Cholesterol To Restrict Microbial Infection

bioRxiv (Cold Spring Harbor Laboratory)(2022)10.1101/2022.10.10.510128

N/A

0.104DataRank · unranked

1 citations

Kristen Johnson, Maikke B. Ohlson, Duo Ma, Lishu Zhang, Michelle Tran +7 more

A concerted mechanism involving ACAT and SREBPs by which oxysterols deplete accessible cholesterol to restrict microbial infection

eLife(2023)10.7554/elife.83534

N/A

0DataRank · unranked

40 citations

Kristen Johnson, Duo Ma, Maikke B. Ohlson, Lishu Zhang, Michelle Tran +7 more

25-Hydroxycholesterol exacerbates vascular leak during acute lung injury

JCI Insight(2023)10.1172/jci.insight.155448

N/A

0DataRank · unranked

20 citations

Eric D. Morrell, Jeffrey G. McDonald, Bonne M. Thompson, Yue Li, Konstantin G. Birukov +10 more

Selective and brain-penetrant lanosterol synthase inhibitors target glioma stem-like cells by inducing 24(S),25-epoxycholesterol production

Cell chemical biology(2023)10.1016/j.chembiol.2023.01.005

N/A

0DataRank · unranked

18 citations

Wentian Wang, Alex Sternisha, Chase D. Corley, Hua-Yu Leo Wang, Xiaoyu Wang +10 more

Endogenous and Therapeutic 25-Hydroxycholesterols May Worsen Early SARS-CoV-2 Pathogenesis in Mice

American Journal of Respiratory Cell and Molecular Biology(2023)10.1165/rcmb.2023-0007oc

N/A

0DataRank · unranked

10 citations

Jennifer H. Madenspacher, Paul J. Baker, Kerry L. Hilligan, Andrea C. Bohrer, Ehydel Castro +10 more

Myocardial steatosis impairs left ventricular diastolic–systolic coupling in healthy humans

The Journal of Physiology(2023)10.1113/jp284272

N/A

0DataRank · unranked

10 citations

Lidia S. Szczepaniak, Manall Jaffery, Daisha J. Cipher, Jeffrey G. McDonald, Mark J. Haykowsky +5 more

Adipose-specific overexpression of human AGPAT2 in mice causes increased adiposity and mild hepatic dysfunction

iScience(2023)10.1016/j.isci.2023.108653

N/A

0DataRank · unranked

4 citations

Katie Tunison, Gonçalo Vale, Jeffrey G. McDonald, Xilong Li, Jay D. Horton +2 more

Author response: A concerted mechanism involving ACAT and SREBPs by which oxysterols deplete accessible cholesterol to restrict microbial infection

(2023)10.7554/elife.83534.sa2

N/A

0DataRank · unranked

1 citations

Kristen Johnson, Duo Ma, Maikke B. Ohlson, Lishu Zhang, Michelle Tran +7 more

LPD-3 as a megaprotein brake for aging and insulin-mTOR signaling in C. elegans

bioRxiv (Cold Spring Harbor Laboratory)(2023)10.1101/2023.02.14.528431

N/A

0DataRank · unranked

1 citations

Bingying Wang, Changnan Wang, Jenny Zu, Huichao Deng, Kang Shen +4 more

An enteroendocrine-microbial axis in the large intestine controls host metabolism

Research Square(2023)10.21203/rs.3.rs-3112286/v1

N/A

0DataRank · unranked

0 citations

Shuai Tan, Jacobo L. Santolaya, Tiffany Wright, Qi Liu, Teppei Fujikawa +10 more

DGAT2 inhibition blocks SREBP-1 cleavage and improves hepatic steatosis by increasing phosphatidylethanolamine in the ER

Cell Metabolism(2024)10.1016/j.cmet.2024.01.011

N/A

0DataRank · unranked

96 citations

Mingfeng Xia, Gonçalo Vale, Simeng Wang, Chai-Wan Kim, Shili Li +4 more

Molecular insights into human phosphatidylserine synthase 1 reveal its inhibition promotes LDL uptake

Cell(2024)10.1016/j.cell.2024.08.004

N/A

0DataRank · unranked

27 citations

Dongyu Li, Gonçalo Vale, Yaoyukun Jiang, Philip Schmiege, Zhongyue Yang +3 more

Assessment of the Cutaneous Hormone Landscapes and Microbiomes in Vulvar Lichen Sclerosus

Journal of Investigative Dermatology(2024)10.1016/j.jid.2024.01.027

N/A

0DataRank · unranked

15 citations

Jessica C. Evans, Methinee Artami, Prithvi Raj, S K Sridharan, Carlos Arana +5 more

LPD-3 as a megaprotein brake for aging and insulin-mTOR signaling in C. elegans

Cell Reports(2024)10.1016/j.celrep.2024.113899

N/A

0DataRank · unranked

9 citations

Bingying Wang, Changnan Wang, Jenny Zu, Huichao Deng, Kang Shen +4 more

Plasma Concentrations of Multiple Oxysterols and Risk of Colorectal Adenomas

Cancer Prevention Research(2024)10.1158/1940-6207.capr-24-0108

N/A

0DataRank · unranked

2 citations

Jeffrey G. McDonald, Bonne M. Thompson, Hugo Pomares‐Millan, Thomas J. Palys, Judy R. Rees +2 more

7212 Racial/Ethnical Differences In Classic And 11-Oxygenated Androgens

Journal of the Endocrine Society(2024)10.1210/jendso/bvae163.277

N/A

0DataRank · unranked

1 citations

Richard J. Auchus, Jeffrey G. McDonald, Juilee Rege, William E. Rainey, Adina F. Turcu +1 more

Genetic regulation and targeted reversal of lysosomal dysfunction and inflammatory sterol metabolism in pulmonary arterial hypertension

bioRxiv (Cold Spring Harbor Laboratory)(2024)10.1101/2024.02.26.582142

N/A

0DataRank · unranked

0 citations

Mona Alotaibi, Hee-Jung Janice Kim, Yi‐Yin Tai, Ying Tang, Wei Sun +24 more

Reviewer #2 (Public Review): DHCR24-mediated sterol homeostasis during spermatogenesis is required for sperm mitochondrial sheath formation and impacts male fertility over time

(2024)10.7554/elife.95627.1.sa1

N/A

0DataRank · unranked

0 citations

Huafeng Wang, Xinbo Zhang, Pablo Fernández-Tussy, Kyung Jo Jeong, Jungmin Choi +5 more

DHCR24-mediated sterol homeostasis during spermatogenesis is required for sperm mitochondrial sheath formation and impacts male fertility over time

eLife(2024)10.7554/elife.95627

N/A

0DataRank · unranked

0 citations

Huafeng Wang, Xinbo Zhang, Pablo Fernández‐Tussy, Kyungjo Jeong, Jungmin Choi +5 more

Lysosomal dysfunction and inflammatory sterol metabolism in pulmonary arterial hypertension

Science(2025)10.1126/science.adn7277

N/A

0DataRank · unranked

47 citations

Mona Alotaibi, Yi‐Yin Tai, Ying Tang, Hee‐Jung J. Kim, Neil J. Kelly +46 more

Paraoxonase-like APMAP maintains endoplasmic-reticulum-associated lipid and lipoprotein homeostasis

Developmental Cell(2025)10.1016/j.devcel.2025.04.008

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0DataRank · unranked

4 citations

Holly Merta, Rupali Ugrankar, Monica R. Hensley, Son N. Tran, Gonçalo Vale +8 more

Protection against ferroptosis through maintaining homeostasis of docosahexaenoate-containing phospholipids

Molecular Cell(2025)10.1016/j.molcel.2025.08.023

N/A

0DataRank · unranked

3 citations

Gonçalo Vale, Yonggang Liang, Shaojie Cui, Shunqing Xu, Jeffrey G. McDonald +2 more

Cutaneous Hormone Sampling and Analysis for Dermatologic Research

Journal of Investigative Dermatology(2025)10.1016/j.jid.2025.05.013

N/A

0DataRank · unranked

2 citations

Shivani Jain, Mauricio J. Velasquez, Hanna Gedamu, Jessica Komarovsky, Jeffrey G. McDonald +2 more

Mitochondrial ABHD11 inhibition drives sterol metabolism to modulate T-cell effector function

Nature Communications(2025)10.1038/s41467-025-65417-4

N/A

0DataRank · unranked

0 citations

Yasmin R Jenkins, Fernando M. Ponce-Garcia, Chloe Moscrop, Iain Perry, Matthew D. Hitchings +29 more

Niche-Specific Reprogramming of Epigenetic Landscapes Drives Myeloid Cell Diversity in Nonalcoholic Steatohepatitis

Immunity(2020)10.1016/j.immuni.2020.04.001

N/A

0DataRank · unranked

434 citations

Ty D. Troutman, Mashito Sakai, Anita Gola, Nathanael J. Spann, Hunter Bennett +18 more

Conserved lipid metabolic reprogramming confers hypoxic and aging resilience

EMBO Reports(2025)10.1038/s44319-025-00664-6

N/A

0DataRank · unranked

0 citations

Gonçalo Vale, Quentinn Pearce, Kaitlyn Kong, Wenbin Zhou, Jeffrey G. McDonald +4 more

Mitochondrial substrate utilization regulates cardiomyocyte cell-cycle progression

Nature Metabolism(2020)10.1038/s42255-020-0169-x

N/A

0DataRank · unranked

243 citations

Nicholas T. Lam, Jainy Savla, Yuji Nakada, Ana Helena Macedo Pereira, Abdallah Elnwasany +29 more

Diverse species-specific phenotypic consequences of loss of function sorting nexin 14 mutations

Scientific Reports(2020)10.1038/s41598-020-70797-2

N/A

0DataRank · unranked

17 citations

Marian Seda, Emma Peskett, Constance Maurer, Gideon Pomeranz, Marcus Ghosh +22 more

Snx14 proximity labeling reveals a role in saturated fatty acid metabolism and ER homeostasis defective in SCAR20 disease

Proceedings of the National Academy of Sciences(2020)10.1073/pnas.2011124117

N/A

0DataRank · unranked

25 citations

Jade Bowerman, Hanaa Hariri, Rupali Ugrankar, Kaitlyn M. Eckert, Chase D. Corley +4 more

An implanted port-catheter system for repeated hepatic arterial infusion of low-density lipoprotein-docosahexaenoic acid nanoparticles in normal rats: A safety study

Toxicology and Applied Pharmacology(2020)10.1016/j.taap.2020.115037

N/A

0DataRank · unranked

5 citations

Junjie Li, Indhumathy Subramaniyan, Gonçalo Vale, Jaideep Chaudhary, Arnida Anwar +7 more

MMAB promotes negative feedback control of cholesterol homeostasis

Nature Communications(2021)10.1038/s41467-021-26787-7

N/A

0DataRank · unranked

28 citations

Alberto Canfrán‐Duque, Noemí Rotllán, Balkrishna Chaube, Bonne M. Thompson, Richard Lee +7 more

Decreased caveolae in AGPAT2 lacking adipocytes is independent of changes in cholesterol or sphingolipid levels: A whole cell and plasma membrane lipidomic analysis of adipogenesis

Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease(2021)10.1016/j.bbadis.2021.166167

N/A

0DataRank · unranked

16 citations

Jeffrey G. McDonald, Gonçalo Vale, Bonne M. Thompson, Ana-María Figueroa, Pablo Tapía +6 more

Ceramide-1-phosphate transfer protein promotes sphingolipid reorientation needed for binding during membrane interaction

Journal of Lipid Research(2021)10.1016/j.jlr.2021.100151

N/A

0DataRank · unranked

6 citations

Jeffrey G. McDonald, Lucy Malinina, Dinshaw J. Patel, Rhoderick E. Brown, Yong‐Guang Gao

Transcriptional integration of distinct microbial and nutritional signals by the small intestinal epithelium

bioRxiv (Cold Spring Harbor Laboratory)(2021)10.1101/2021.11.01.465976

N/A

0DataRank · unranked

0 citations

James Davison, Cecelia Kelly, Gilberto Padilla Mercado, Jia Wen, Briana R. Davis +7 more

Targeting de novo lipogenesis and the Lands cycle induces ferroptosis in KRAS-mutant lung cancer

Nature Communications(2022)10.1038/s41467-022-31963-4

N/A

0DataRank · unranked

172 citations

Cristina Andreani, Gonçalo Vale, Stefano Berto, Margherita Melegari, A. Colleen Crouch +17 more

Loss of heat shock factor initiates intracellular lipid surveillance by actin destabilization

Cell Reports(2022)10.1016/j.celrep.2022.111493

N/A

0DataRank · unranked

23 citations

Sonja L. B. Arneaud, Naureen Wajahat, Jordan M. Wall, Lexus Tatge, Shaghayegh T. Beheshti +9 more

Association of demographic and health characteristics with circulating oxysterol concentrations

Journal of clinical lipidology(2022)10.1016/j.jacl.2022.03.012

N/A

0DataRank · unranked

13 citations

Jeffrey G. McDonald, Bonne M. Thompson, Enat Arega, Thomas J. Palys, Judy R. Rees +3 more

Desmosterol and 7-dehydrocholesterol concentrations in post mortem brains of depressed people: The role of trazodone

Translational Psychiatry(2022)10.1038/s41398-022-01903-3

N/A

0DataRank · unranked

11 citations

Jayme M. Palka, Bonne M. Thompson, Jeffrey G. McDonald, Carol A. Tamminga, Can Cenik +2 more

Repeated trans-arterial treatments of LDL-DHA nanoparticles induce multiple pathways of tumor cell death in hepatocellular carcinoma bearing rats

Frontiers in Oncology(2022)10.3389/fonc.2022.1052221

N/A

0DataRank · unranked

8 citations

Junjie Li, Gonçalo Vale, Jaideep Chaudhary, Arnida Anwar, Jeffrey G. McDonald +4 more

A megaprotein-based molecular bridge critical for lipid trafficking and cold resilience

bioRxiv (Cold Spring Harbor Laboratory)(2022)10.1101/2022.08.25.505359

N/A

0DataRank · unranked

1 citations

Bingying Wang, Taruna Pandey, Yong Long, Jianxiu Zhang, Fiona Oh +13 more

Structural and functional insights into Spns2-mediated transport of sphingosine-1-phosphate

Cell(2023)10.1016/j.cell.2023.04.028

N/A

0DataRank · unranked

59 citations

Shahbaz Ahmed, Hongtu Zhao, Nadia Elghobashi‐Meinhardt, Yaxin Dai, Jae Hun Kim +4 more

Macrophage-to-endothelial cell crosstalk by the cholesterol metabolite 27HC promotes atherosclerosis in male mice

Nature Communications(2023)10.1038/s41467-023-39586-z

N/A

0DataRank · unranked

51 citations

Lin Xu, Haiyan Chu, Jun Peng, Anastasia Sacharidou, Hsi-Hsien Hsieh +15 more