David J. Huggins

Tri-Institutional Therapeutics Discovery Institute

Biochemistry, Genetics and Molecular BiologyComputer ScienceChemistry

Pilot corpus only

This score is computed over theSindex pilot corpus and does not cover the full scientific literature. Scores are relative to papers we have ingested — papers, authors, and institutions outside the pilot are not represented. Methodology.

Top 100%percentile

0Author DataRank

Indexed papers

0in pilot corpus

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Papers

Driven by 10 papers. Top paper: “Lead Optimization of Small Molecule ENL YEATS Inhibitors to Enable In Vivo Studies: Discovery of TDI-11055”.

Lead Optimization of Small Molecule ENL YEATS Inhibitors to Enable In Vivo Studies: Discovery of TDI-11055

ACS Medicinal Chemistry Letters(2024)10.1021/acsmedchemlett.4c00016

N/A

0.345DataRank · unranked

9 citations

Tanweer A. Khan, Michael W. Miller, Yoshiyuki Fukase, Jérémie Vendôme, Carolina Adura +11 more

Next Generation Neuropeptide Y Receptor Small Molecule Agonists Inhibit Mosquito Biting Behavior

bioRxiv (Cold Spring Harbor Laboratory)(2024)10.1101/2024.02.28.582529

N/A

0.260DataRank · unranked

4 citations

Leigh A. Baxt, Tanweer A. Khan, Mayako Michino, Michael Miller, David J. Huggins +4 more

On-demand male contraception via acute inhibition of soluble adenylyl cyclase

Nature Communications(2023)10.1038/s41467-023-36119-6

N/A

0DataRank · unranked

83 citations

Thomas Rossetti, Jacob Ferreira, Lubna Ghanem, Carla Ritagliati, Robert W. Myers +7 more

Using a function-first ‘scout fragment’-based approach to develop allosteric covalent inhibitors of conformationally dynamic helicase mechanoenzymes

bioRxiv (Cold Spring Harbor Laboratory)(2023)10.1101/2023.09.25.559391

N/A

0DataRank · unranked

1 citations

Patrick M. M. Shelton, Tyler K. Heiss, Paul Dominic B. Olinares, Lauren E. Vostal, Heather Soileau +11 more

Indazole to 2‐Cyanoindole Scaffold Progression for Mycobacterial Lipoamide Dehydrogenase Inhibitors Achieves Extended Target Residence Time and Improved Antibacterial Activity

Angewandte Chemie International Edition(2024)10.1002/anie.202407276

N/A

0DataRank · unranked

4 citations

John D. Ginn, Tomasz Kochańczyk, Nancy Arango, Xiuju Jiang, David J. Huggins +7 more

Indazole to 2‐Cyanoindole Scaffold Progression for Mycobacterial Lipoamide Dehydrogenase Inhibitors Achieves Extended Target Residence Time and Improved Antibacterial Activity

Angewandte Chemie(2024)10.1002/ange.202407276

N/A

0DataRank · unranked

2 citations

John D. Ginn, Tomasz Kochańczyk, Nancy Arango, Xiuju Jiang, David J. Huggins +7 more

A potent and selective TNKS2 inhibitor for tumor-selective WNT suppression

bioRxiv (Cold Spring Harbor Laboratory)(2025)10.1101/2025.03.04.641305

N/A

0DataRank · unranked

0 citations

Brandon F Malone, Efrat Finkin-Groner, Shan Sun, Rui Liang, Miguel Foronda +15 more

Deglycase-activity oriented screening to identify DJ-1 inhibitors

RSC Medicinal Chemistry(2021)10.1039/d1md00062d

N/A

0DataRank · unranked

21 citations

Efrat Finkin-Groner, Yoshiyuki Fukase, Qingfei Zheng, Shan Sun, Mayako Michino +4 more

Discovery of Novel Isofunctional SARS-CoV-2 NSP14 RNA Cap Methyltransferase Inhibitors by Structure-Based Virtual Screening

ACS Medicinal Chemistry Letters(2025)10.1021/acsmedchemlett.5c00339

N/A

0DataRank · unranked

0 citations

Mayako Michino, David J. Huggins, Aitor Garzia, Jada A. Davis, Michael W. Miller +10 more

Whole Cell Active Inhibitors of Mycobacterial Lipoamide Dehydrogenase Afford Selectivity over the Human Enzyme through Tight Binding Interactions

ACS Infectious Diseases(2021)10.1021/acsinfecdis.0c00788

N/A

0DataRank · unranked

7 citations

Xiuju Jiang, Shan Sun, Mayako Michino, David J. Huggins, Zodwa Mbambo +15 more