Zina Itkin

National Center for Advancing Translational Sciences

Biochemistry, Genetics and Molecular BiologyComputer ScienceMedicine

Pilot corpus only

This score is computed over theSindex pilot corpus and does not cover the full scientific literature. Scores are relative to papers we have ingested — papers, authors, and institutions outside the pilot are not represented. Methodology.

Top 2%percentile

4.0Author DataRank

Indexed papers

4in pilot corpus

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Why this DataRank?

An author's DataRank is the sum of the DataRanks of all 4 indexed papers attributed to them. A prolific author with many moderate-impact papers can outrank one with a single high-impact paper.

Author scores recompute whenever paper DataRanks are refreshed, so this number lags the underlying paper scores by at most one batch run.

Read the full methodology →

The highest-impact dataset this researcher has shared, ranked by DataRank — the single contribution doing the most to lift their data-sharing standing.

Real-time sharing of drug screening data on the NCATS OpenData Portal accelerates translational research

bioRxiv (Cold Spring Harbor Laboratory)(2020)10.1101/2020.06.04.135046

Top 7%

3.3DataRank

Top 7%108 citations

Tongan Zhao, Richard T. Eastman, Xin Hu, Ke Wang, Mark Backus +31 more

Papers

Driven by 36 papers — median percentile 52. Top paper: “Therapeutic targeting of ATR yields durable regressions in small cell lung cancers with high replication stress”.

Therapeutic targeting of ATR yields durable regressions in small cell lung cancers with high replication stress

Cancer Cell(2021)10.1016/j.ccell.2021.02.014

N/A

4.8DataRank · unranked

178 citations

Nobuyuki Takahashi, Vinodh N. Rajapakse, Xiaohu Zhang, Yilun Sun, Michele Ceribelli +36 more

Real-time sharing of drug screening data on the NCATS OpenData Portal accelerates translational research

bioRxiv (Cold Spring Harbor Laboratory)(2020)10.1101/2020.06.04.135046

Top 7%

3.3DataRank

Top 7%108 citations

Tongan Zhao, Richard T. Eastman, Xin Hu, Ke Wang, Mark Backus +31 more

Synergistic and Antagonistic Drug Combinations against SARS-CoV-2

Molecular Therapy(2020)10.1016/j.ymthe.2020.12.016

N/A

0.728DataRank · unranked

127 citations

Lu Chen, Richard T. Eastman, Zina Itkin, Paul Shinn, Catherine Z. Chen +8 more

A landscape of response to drug combinations in non-small cell lung cancer

Nature Communications(2023)10.1038/s41467-023-39528-9

N/A

0.604DataRank · unranked

55 citations

Patricia Greninger, Xiaohu Zhang, Adam Friedman, Arnaud Amzallag, Eliane Cortez +25 more

Targeting neddylation sensitizes colorectal cancer to topoisomerase I inhibitors by inactivating the DCAF13-CRL4 ubiquitin ligase complex

Nature Communications(2023)10.1038/s41467-023-39374-9

N/A

0.510DataRank · unranked

29 citations

Simone A. Baechler, Xiaohu Zhang, Suresh Kumar, Valentina M. Factor, Yasuhiro Arakawa +20 more

AI-driven discovery of synergistic drug combinations against pancreatic cancer

Nature Communications(2025)10.1038/s41467-025-56818-6

N/A

0.494DataRank · unranked

26 citations

Sankalp Jain, Elena Barnaeva, Wengong Jin, Joshua E. Hochuli, Zina Itkin +14 more

Drug combinations identified by high-throughput screening promote cell cycle transition and upregulate Smad pathways in myeloma

Cancer Letters(2023)10.1016/j.canlet.2023.216284

N/A

0.468DataRank · unranked

10 citations

Snehal Gaikwad, Wendy Dubois, Nana Gyabaah-Kessie, Shuling Zhang, Sayeh Gorjifard +27 more

High-throughput approaches to uncover synergistic drug combinations in leukemia

SLAS DISCOVERY(2023)10.1016/j.slasd.2023.04.004

Top 42%

0.446DataRank

Top 42%9 citations

Meng Wang, Michele Ceribelli, Aleksandra M. Michalowska, Stefan Golas, Erin Beck +13 more

Modulation of Triple Artemisinin-Based Combination Therapy Pharmacodynamics by Plasmodium falciparum Genotype

ACS Pharmacology & Translational Science(2020)10.1021/acsptsci.0c00110

N/A

0.442DataRank · unranked

18 citations

Zina Itkin, Lu Chen, Gergely Zahoránszky-Köhalmi, Chanaki Amaratunga, Olivo Miotto +10 more

Discovery of Synergistic and Antagonistic Drug Combinations against SARS-CoV-2 In Vitro

bioRxiv (Cold Spring Harbor Laboratory)(2020)10.1101/2020.06.29.178889

N/A

0.416DataRank · unranked

15 citations

Lu Chen, Richard T. Eastman, Zina Itkin, Paul Shinn, Catherine Chen +8 more

Activity of the Ubiquitin-activating Enzyme Inhibitor TAK-243 in Adrenocortical Carcinoma Cell Lines, Patient-derived Organoids, and Murine Xenografts

Cancer Research Communications(2024)10.1158/2767-9764.crc-24-0085

N/A

0.396DataRank · unranked

13 citations

Ukhyun Jo, Suresh Kumar, Nai-Yun Sun, Fathi Elloumi, Anish Thomas +18 more

High-resolution acoustic ejection mass spectrometry for high-throughput library screening

SLAS TECHNOLOGY(2024)10.1016/j.slast.2024.100199

N/A

0.360DataRank · unranked

10 citations

D. Calabrese, Zina Itkin, Glenn Gomba, Min Shen, Meghav Verma +9 more

Multi-Component, Time-Course screening to develop combination cancer therapies based on synergistic toxicity

Proceedings of the National Academy of Sciences(2024)10.1073/pnas.2413372121

N/A

0.330DataRank · unranked

8 citations

Frances A. Tosto, Xiaohu Zhang, Christopher Melani, Mark Roschewski, Erin Beck +13 more

A Comprehensive Collection of Pain and Opioid Use Disorder Compounds for High-Throughput Screening and Artificial Intelligence-Driven Drug Discovery

ACS Pharmacology & Translational Science(2024)10.1021/acsptsci.4c00256

Top 54%

0.310DataRank

Top 54%5 citations

Paul Shinn, Zina Itkin, Lin Ye, Ya-Qin Zhang, Min Shen +3 more

Application of temperature-responsive HIS-tag fluorophores to differential scanning fluorimetry screening of small molecule libraries

Frontiers in Pharmacology(2022)10.3389/fphar.2022.1040039

N/A

0.241DataRank · unranked

4 citations

Bolormaa Baljinnyam, Zina Itkin, Sankalp Jain, Ganesha Rai, Alexey Zakharov +3 more

Modulation of triple artemisinin-based combination therapy pharmacodynamics by Plasmodium falciparum genotype

bioRxiv (Cold Spring Harbor Laboratory)(2020)10.1101/2020.07.03.187039

N/A

0.104DataRank · unranked

1 citations

Zina Itkin, Lu Chen, Gergely Zahoránszky-Köhalmi, Chanaki Amaratunga, Olivo Miotto +10 more

Preclinical Evaluation of the FGFR-Family Inhibitor Futibatinib for Pediatric Rhabdomyosarcoma

Cancers(2023)10.3390/cancers15164034

N/A

0DataRank · unranked

13 citations

Adam Cheuk, Kristine A. Isanogle, Christina M. Robinson, Xiaohu Zhang, Michele Ceribelli +22 more

A Comprehensive Collection of Pain and Opioid Use Disorder Compounds for High-Throughput Screening and Artificial Intelligence-Driven Drug Discovery

bioRxiv (Cold Spring Harbor Laboratory)(2024)10.1101/2024.04.21.590471

Top 100%

0DataRank

Top 100%0 citations

Paul Shinn, Zina Itkin, Lin Ye, Ya-qin Zhang, Min Shen +3 more

Limitations of acyclovir and identification of potent HSV antivirals using 3D bioprinted human skin equivalents

bioRxiv (Cold Spring Harbor Laboratory)(2024)10.1101/2024.12.04.626896

N/A

0DataRank · unranked

0 citations

Ian Hayman, Kristy Derr, Paige Derr, Shayne Frebert, Zina Itkin +10 more

Limitations of acyclovir and identification of potent HSV antivirals using 3D bioprinted human skin equivalents

Nature Communications(2025)10.1038/s41467-025-64245-w

N/A

0DataRank · unranked

7 citations

Ian Hayman, Kristy Derr, Paige Derr, Shayne Frebert, Zina Itkin +10 more

Large-scale human myeloma cell line small molecule compound screen dataset

Scientific Data(2025)10.1038/s41597-025-04989-8

N/A

0DataRank · unranked

1 citations

John K. Simmons, Sayeh Gorjifard, Aleksandra M. Michalowski, Kelli M. Wilson, Xiaohu Zhang +10 more

The SARS-CoV-2 Cytopathic Effect Is Blocked by Lysosome Alkalizing Small Molecules

ACS Infectious Diseases(2020)10.1021/acsinfecdis.0c00349

N/A

0DataRank · unranked

93 citations

Catherine Z. Chen, Robert Bostwick, Lynn Rasmussen, Bruce Nguyen Tran, Yu-Shan Cheng +21 more

Drug Repurposing Screen for Compounds Inhibiting the Cytopathic Effect of SARS-CoV-2

bioRxiv (Cold Spring Harbor Laboratory)(2020)10.1101/2020.08.18.255877

N/A

0DataRank · unranked

30 citations

Paul Shinn, Zina Itkin, Richard T. Eastman, Robert Bostwick, Lynn Rasmussen +14 more

Deep learning identifies synergistic drug combinations for treating COVID-19

Proceedings of the National Academy of Sciences(2021)10.1073/pnas.2105070118

N/A

0DataRank · unranked

174 citations

Jonathan Stokes, Richard T. Eastman, Zina Itkin, Alexey Zakharov, James J. Collins +3 more

Drug Repurposing Screen for Compounds Inhibiting the Cytopathic Effect of SARS-CoV-2

Frontiers in Pharmacology(2021)10.3389/fphar.2020.592737

N/A

0DataRank · unranked

95 citations

Paul Shinn, Zina Itkin, Richard T. Eastman, Robert Bostwick, Lynn Rasmussen +14 more

Application of niclosamide and analogs as small molecule inhibitors of Zika virus and SARS-CoV-2 infection

Bioorganic & Medicinal Chemistry Letters(2021)10.1016/j.bmcl.2021.127906

N/A

0DataRank · unranked

24 citations

Miao Xu, Xin Hu, Emily M. Lee, Xiao Lü, Ruili Huang +19 more

Human Pluripotent Stem Cells for High-Throughput Drug Screening and Characterization of Small Molecules

Methods in molecular biology(2021)10.1007/7651_2021_394

N/A

0DataRank · unranked

10 citations

Pei‐Hsuan Chu, Claire Malley, John Braisted, Pinar Ormanoglu, Ruili Huang +9 more

A high throughput screening assay for inhibitors of SARS-CoV-2 pseudotyped particle entry

bioRxiv (Cold Spring Harbor Laboratory)(2021)10.1101/2021.10.04.463106

N/A

0DataRank · unranked

6 citations

Manisha Pradhan, Kirill Gorshkov, Jennifer D. Petersen, Min Shen, Hui Guo +11 more

A humanized nanobody phage display library yields potent binders of SARS CoV-2 spike

bioRxiv (Cold Spring Harbor Laboratory)(2021)10.1101/2021.10.22.465476

N/A

0DataRank · unranked

1 citations

Juliana da Fonseca Rezende e Mello, Bryan D. Fleming, Alex Renn, Catherine Z. Chen, Xin Hu +26 more

Correction to: Human Pluripotent Stem Cells for High-Throughput Drug Screening and Characterization of Small Molecules

Methods in molecular biology(2021)10.1007/7651_2021_458

N/A

0DataRank · unranked

1 citations

Pei‐Hsuan Chu, Claire Malley, John Braisted, Pinar Ormanoglu, Ruili Huang +9 more

Inhibiting SARS‐CoV‐2 infection with lysosomal alkalizers

The FASEB Journal(2021)10.1096/fasebj.2021.35.s1.02122

N/A

0DataRank · unranked

0 citations

Catherine Chen, Robert Bostwick, Lynn Rasmussen, Bruce Nguyen Tran, Yu‐Shan Cheng +21 more

A high throughput screening assay for inhibitors of SARS-CoV-2 pseudotyped particle entry

SLAS DISCOVERY(2022)10.1016/j.slasd.2021.12.005

N/A

0DataRank · unranked

26 citations

Manisha Pradhan, Kirill Gorshkov, Jennifer D. Petersen, Min Shen, Hui Guo +11 more

A humanized nanobody phage display library yields potent binders of SARS CoV-2 spike

PLoS ONE(2022)10.1371/journal.pone.0272364

N/A

0DataRank · unranked

18 citations

Juliana da Fonseca Rezende e Mello, Bryan D. Fleming, Alex Renn, Catherine Z. Chen, Xin Hu +27 more

A multiparametric calcium signal screening platform using iPSC-derived cortical neural spheroids.

SLAS DISCOVERY(2022)10.1016/j.slasd.2022.01.003

N/A

0DataRank · unranked

17 citations

Caroline E. Strong, Brittney Van Hese, Xin Hu, Zina Itkin, Yu‐Chi Chen +8 more

Suite of TMPRSS2 Assays for Screening Drug Repurposing Candidates as Potential Treatments of COVID-19

ACS Infectious Diseases(2022)10.1021/acsinfecdis.2c00172

N/A

0DataRank · unranked

8 citations

John Janiszewski, Catherine Z. Chen, Miao Xu, Kelli M. Wilson, Stephen C. Kales +12 more

High-throughput and targeted drug screens identify pharmacological candidates against MiT-translocation renal cell carcinoma

Journal of Experimental & Clinical Cancer Research(2023)10.1186/s13046-023-02667-4

N/A

0DataRank · unranked

20 citations

Laura S. Schmidt, Kelli M. Wilson, Christopher J. Ricketts, Carole Sourbier, Cathy D. Vocke +23 more

Zina Itkin

Indexed papers

Top data-sharing exemplar

Papers