Rafael M. Couñago

University of North Carolina at Charlotte

Also affiliated with University of North Carolina at Chapel Hill, University of North Carolina Health Care, Universidade Estadual de Campinas (UNICAMP), Structural Genomics Consortium, Centro de Genética Clínica, International Centre for Genetic Engineering and Biotechnology

MedicineComputer ScienceMaterials ScienceBiochemistry, Genetics and Molecular Biology

Pilot corpus only

This score is computed over theSindex pilot corpus and does not cover the full scientific literature. Scores are relative to papers we have ingested — papers, authors, and institutions outside the pilot are not represented. Methodology.

Top 100%percentile

0Author DataRank

Indexed papers

0in pilot corpus

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Papers

Driven by 30 papers. Top paper: “SGC-CAMKK2-1: A Chemical Probe for CAMKK2”.

SGC-CAMKK2-1: A Chemical Probe for CAMKK2

Cells(2023)10.3390/cells12020287

N/A

0.360DataRank · unranked

10 citations

Yi Liang, Thomas L. Pulliam, Chenchu Lin, Dominik Awad, Benjamin J. Eduful +19 more

Enantioselective Chemical Probe for Chikungunya nsP2 Helicase with Antialphaviral Activity

ACS Infectious Diseases(2025)10.1021/acsinfecdis.5c00351

N/A

0.292DataRank · unranked

6 citations

Hans J. Oh, John D. Sears, Chun‐Hsing Chen, Anand Vala, Shubin Liu +20 more

Strategic Fluorination to Achieve a Potent, Selective, Metabolically Stable, and Orally Bioavailable Inhibitor of CSNK2

Molecules(2024)10.3390/molecules29174158

N/A

0.165DataRank · unranked

2 citations

Xuan Yang, Jeffery L. Smith, Sharon Taft-Benz, Stefanie Howell, Rebekah J. Dickmander +12 more

N -Alkyl Sulfamates as a New Class of nsP2 Cysteine Protease Inhibitors with Broad Spectrum Antialphaviral Activity

bioRxiv (Cold Spring Harbor Laboratory)(2025)10.1101/2025.06.30.662352

N/A

0.104DataRank · unranked

1 citations

John D. Sears, Mohammad Anwar Hossain, Edwin G. Tse, Stefanie Howell, Jane Burdick +10 more

Identification of P218 as a Potent Inhibitor of Mycobacteria Ulcerans DHFR

ChemRxiv(2020)10.26434/chemrxiv.12899420.v1

N/A

0DataRank · unranked

0 citations

Rachael Zigweid, Peter J. Myler, Stephen J. Mayclin, Rafael M. Couñago, Bart L. Staker +1 more

Identification of P218 as a Potent Inhibitor of Mycobacteria Ulcerans DHFR

ChemRxiv(2020)10.26434/chemrxiv.12899420

N/A

0DataRank · unranked

0 citations

Rachael Zigweid, Peter J. Myler, Stephen J. Mayclin, Rafael M. Couñago, Bart L. Staker +1 more

Raising the Bar(-seq) in Leishmania Genetic Screens

Trends in Parasitology(2021)10.1016/j.pt.2021.03.002

N/A

0DataRank · unranked

1 citations

Rafael M. Couñago, Nilmar Silvio Moretti, Tiago Rodrigues Ferreira

Development of the First Covalent Monopolar Spindle Kinase 1 (MPS1/TTK) Inhibitor

ChemRxiv(2021)10.26434/chemrxiv.14601264.v1

N/A

0DataRank · unranked

2 citations

André da Silva Santiago, Caio dos Reis, Jéssica E. Takarada, Priscila Mezzomo, Katlin B. Massirer +9 more

Development of the First Covalent Monopolar Spindle Kinase 1 (MPS1/TTK) Inhibitor

ChemRxiv(2021)10.26434/chemrxiv.14601264

N/A

0DataRank · unranked

0 citations

André da Silva Santiago, Caio dos Reis, Jéssica E. Takarada, Priscila Mezzomo, Katlin B. Massirer +9 more

Development of the First Covalent Monopolar Spindle Kinase 1 (MPS1/TTK) Inhibitor

Journal of Medicinal Chemistry(2022)10.1021/acs.jmedchem.1c01165

N/A

0DataRank · unranked

27 citations

André da Silva Santiago, Martin P. Schwalm, Zexi Hu, C.V. dos Reis, Jéssica E. Takarada +11 more

SGC-CAMKK2-1: A chemical probe for CAMKK2

bioRxiv (Cold Spring Harbor Laboratory)(2022)10.1101/2022.10.18.512752

N/A

0DataRank · unranked

0 citations

Yi Liang, Thomas L. Pulliam, Chenchu Lin, Dominik Awad, Benjamin J. Eduful +19 more

Novel dihydropteridinone derivatives as potent and selective inhibitors of the understudied human vaccinia-related kinase 1 (VRK1)

ChemRxiv(2023)10.26434/chemrxiv-2023-cmgsv

N/A

0DataRank · unranked

1 citations

Luiz Antônio Dutra, Michael Hawgood, C.V. dos Reis, Ricardo A. M. Serafim, Marcos Antonio Ferreira +21 more

Identification of a cell-active chikungunya virus nsP2 protease inhibitor using a covalent fragment-based screening approach

Proceedings of the National Academy of Sciences(2024)10.1073/pnas.2409166121

N/A

0DataRank · unranked

31 citations

John D. Sears, Tina M. Leisner, P. Brian Hardy, Anirban Ghoshal, Mohammad Anwar Hossain +24 more

More than an Amide Bioisostere: Discovery of 1,2,4-Triazole-containing Pyrazolo[1,5- a ]pyrimidine Host CSNK2 Inhibitors for Combatting β-Coronavirus Replication

Journal of Medicinal Chemistry(2024)10.1021/acs.jmedchem.4c00962

N/A

0DataRank · unranked

18 citations

Xuan Yang, Jeffery L. Smith, Rebekah J. Dickmander, Jason W. Brown, Tammy M. Havener +13 more

Rational Exploration of 2,4-Diaminopyrimidines as DHFR Inhibitors Active against Mycobacterium abscessus and Mycobacterium avium, Two Emerging Human Pathogens

Journal of Medicinal Chemistry(2024)10.1021/acs.jmedchem.4c01594

N/A

0DataRank · unranked

6 citations

Vitor M. Almeida, Jaryd Sullivan, Ian de Toledo, C.V. dos Reis, Micael Rodrigues Cunha +20 more

More than an Amide Bioisostere: Discovery of 1,2,4-Triazole-containing Pyrazolo[1,5-a]pyrimidine Host CSNK2 Inhibitors for Combatting β-Coronavirus Replication

ChemRxiv(2024)10.26434/chemrxiv-2024-h2x2b

N/A

0DataRank · unranked

0 citations

Xuan Yang, Jeffery L. Smith, Rebekah J. Dickmander, Joshua B. Brown, Tammy M. Havener +13 more

Development of a Second-Generation, In Vivo Chemical Probe for PIKfyve

Journal of Medicinal Chemistry(2025)10.1021/acs.jmedchem.4c02531

N/A

0DataRank · unranked

9 citations

Frances M. Bashore, Jeffrey L. Smith, Tammy M. Havener, Stefanie Howell, Haoxi Li +4 more

Identification of Direct-Acting nsP2 Helicase Inhibitors with Antialphaviral Activity

Journal of Medicinal Chemistry(2025)10.1021/acs.jmedchem.5c00635

N/A

0DataRank · unranked

9 citations

John D. Sears, Kacey M. Talbot, Yuan-Wei Norman Su, Scott Houliston, Mohammad Anwar Hossain +27 more

A covalent chemical probe for Chikungunya nsP2 cysteine protease with antialphaviral activity and proteome-wide selectivity

Scientific Reports(2025)10.1038/s41598-025-91673-x

N/A

0DataRank · unranked

9 citations

Edwin G. Tse, Mohammad Anwar Hossain, Kesatebrhan Haile Asressu, Eric M. Merten, John D. Sears +22 more

Chemoproteomic Profiling of C. albicans for Characterization of Antifungal Kinase Inhibitors

Journal of Medicinal Chemistry(2025)10.1021/acs.jmedchem.5c00097

N/A

0DataRank · unranked

6 citations

Meganathan Nandakumar, Aurora Cabrera, Bonnie Yiu, Emily Puumala, Zhongle Liu +12 more

N -Alkyl Sulfamates as a New Class of nsP2 Cysteine Protease Inhibitors with Broad-Spectrum Antialphaviral Activity

Journal of Medicinal Chemistry(2025)10.1021/acs.jmedchem.5c01802

N/A

0DataRank · unranked

2 citations

John D. Sears, Mohammad Anwar Hossain, Edwin G. Tse, Stefanie Howell, Jane Burdick +10 more

An Enantioselective Chemical Probe for Chikungunya nsP2 Helicase with Antialphaviral Activity

bioRxiv (Cold Spring Harbor Laboratory)(2025)10.1101/2025.04.24.650479

N/A

0DataRank · unranked

1 citations

Hans J. Oh, John D. Sears, Chun‐Hsing Chen, Anand Vala, Shubin Liu +20 more

Chemoproteomic Profiling of C. albicans for Characterization of Anti-fungal Kinase Inhibitors

bioRxiv (Cold Spring Harbor Laboratory)(2025)10.1101/2025.01.10.632200

N/A

0DataRank · unranked

0 citations

Meganathan Nandakumar, Aurora Cabrera, Bonnie Yiu, Emily Puumala, Zhongle Liu +12 more

Identification of Spirodioxolane nsP2 Helicase Inhibitors with Antialphaviral Activity

ChemRxiv(2025)10.26434/chemrxiv-2025-mfts7

N/A

0DataRank · unranked

0 citations

John D. Sears, Muthu Bose Ramalingam, Rahman Shah Zaib Saleem, Zachary W. Davis‐Gilbert, Mohammad Anwar Hossain +10 more

Rational Exploration of 2,4-Diaminopyrimidines as DHFR Inhibitors Active against Mycobacterium abscessus and Mycobacterium avium, Two Emerging Human Pathogens

UNC Libraries(2025)10.17615/awaa-8n71

N/A

0DataRank · unranked

0 citations

Ronaldo A. Pilli, K.P. Battaile, Ian de Toledo, Scott Lovell, Kevin D. Read +20 more

In Depth Analysis of Kinase Cross Screening Data to Identify CAMKK2 Inhibitory Scaffolds

Molecules(2020)10.3390/molecules25020325

N/A

0DataRank · unranked

37 citations

John W. Scott, Joseph Pilotte, André da Silva Santiago, Christopher G. Langendorf, Jonathan S. Oakhill +7 more

Identification of spirodioxolane nsP2 helicase inhibitors with antialphaviral activity

RSC Medicinal Chemistry(2025)10.1039/d5md00772k

N/A

0DataRank · unranked

0 citations

John D. Sears, M. Bose, Rahman Shah Zaib Saleem, Zachary W. Davis‐Gilbert, Mohammad Anwar Hossain +10 more

In depth analysis of kinase cross screening data to identify CAMKK2 inhibitory scaffolds

bioRxiv (Cold Spring Harbor Laboratory)(2020)10.1101/2020.01.08.883009

N/A

0DataRank · unranked

11 citations

John W. Scott, Joseph Pilotte, André de S. Santiago, Christopher G. Langendorf, Jonathan S. Oakhill +7 more

Hinge Binder Scaffold Hopping Identifies Potent Calcium/Calmodulin-Dependent Protein Kinase Kinase 2 (CAMKK2) Inhibitor Chemotypes

ChemRxiv(2020)10.26434/chemrxiv.13484763

N/A

0DataRank · unranked

1 citations

Sean O’Byrne, Louisa Temme, Christopher R. M. Asquith, Yi Liang, Alfredo Picado +18 more

Hinge Binder Scaffold Hopping Identifies Potent Calcium/Calmodulin-Dependent Protein Kinase Kinase 2 (CAMKK2) Inhibitor Chemotypes

ChemRxiv(2020)10.26434/chemrxiv.13484763.v1

N/A

0DataRank · unranked

0 citations

Sean O’Byrne, Louisa Temme, Christopher R. M. Asquith, Yi Liang, Alfredo Picado +18 more