Noelle S. Williams

The University of Texas Southwestern Medical Center

MedicineBiochemistry, Genetics and Molecular Biology

Pilot corpus only

This score is computed over theSindex pilot corpus and does not cover the full scientific literature. Scores are relative to papers we have ingested — papers, authors, and institutions outside the pilot are not represented. Methodology.

Top 100%percentile

0Author DataRank

Indexed papers

1in pilot corpus

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Why this DataRank?

An author's DataRank is the sum of the DataRanks of all 1 indexed paper attributed to them. A prolific author with many moderate-impact papers can outrank one with a single high-impact paper.

Author scores recompute whenever paper DataRanks are refreshed, so this number lags the underlying paper scores by at most one batch run.

Read the full methodology →

Papers

Driven by 35 papers. Top paper: “Small molecule–mediated disruption of Wnt-dependent signaling in tissue regeneration and cancer”.

Small molecule–mediated disruption of Wnt-dependent signaling in tissue regeneration and cancer

Nature Chemical Biology(2009)10.1038/nchembio.137

N/A

1.1DataRank · unranked

1394 citations

Michael E Dodge, Wei Tang, Jianming Lu, Zhiqiang Ma, Chih-Wei Fan +13 more

Selective and brain-penetrant lanosterol synthase inhibitors target glioma stem-like cells by inducing 24(S),25-epoxycholesterol production

Cell chemical biology(2023)10.1016/j.chembiol.2023.01.005

N/A

0.767DataRank · unranked

18 citations

Wentian Wang, Alex Sternisha, Chase D. Corley, Hua-Yu Leo Wang, Xiaoyu Wang +10 more

Leveraging an NQO1 Bioactivatable Drug for Tumor-Selective Use of Poly(ADP-ribose) Polymerase Inhibitors

Cancer Cell(2016)10.1016/j.ccell.2016.11.006

N/A

0.735DataRank · unranked

133 citations

Edward A. Motea, Zachary R. Moore, Jun Yao, Ying Dong, Gaurab Chakrabarti +19 more

Inhibition of the de novo pyrimidine biosynthesis pathway limits ribosomal RNA transcription causing nucleolar stress in glioblastoma cells

PLoS Genetics(2020)10.1371/journal.pgen.1009117

N/A

0.655DataRank · unranked

78 citations

Niranjan Venkateswaran, Jessica A. Kilgore, Suman Kanji, Jungsoo Han, Spencer Barnes +5 more

Targeting ESR1 mutation–induced transcriptional addiction in breast cancer with BET inhibition

JCI Insight(2022)10.1172/jci.insight.151851

N/A

0.396DataRank · unranked

13 citations

Qian Wang, Sunil Kumar, Venkat S. Malladi, Szu‐Yuan Wu, Shuguang Wei +19 more

Susceptible bacteria can survive antibiotic treatment in the mammalian gastrointestinal tract without evolving resistance

Cell Host & Microbe(2024)10.1016/j.chom.2024.01.012

N/A

0.373DataRank · unranked

11 citations

Parastoo Sabaeifard, Muhammed Sadik Yildiz, A. L. Lyon, Laura Coughlin, Sara Ahmed +14 more

Short peptides based on the conserved regions of MIEN1 protein exhibit anticancer activity by targeting the MIEN1 signaling pathway

Journal of Biological Chemistry(2024)10.1016/j.jbc.2024.105680

N/A

0.364DataRank · unranked

8 citations

Priyanka P. Desai, Antariksh Tyagi, Jana B. Lampe, Yogesh Srivastava, Michael Donkor +6 more

Pharmacologic reversal of advanced Alzheimer’s disease in mice and identification of potential therapeutic nodes in human brain

Cell Reports Medicine(2025)10.1016/j.xcrm.2025.102535

N/A

0.360DataRank · unranked

10 citations

Edwin Vázquez-Rosa, Sunil Jamuna Tripathi, Min-Kyoo Shin, Youngmin Yu, Matasha Dhar +31 more

Orthogonal Hydroxyl Functionalization of cGAMP Confers Metabolic Stability and Enables Antibody Conjugation

ACS Central Science(2023)10.1021/acscentsci.3c01122

N/A

0.292DataRank · unranked

6 citations

Lin You, Liping Li, Jessica A. Kilgore, Shun Liu, Xiaoyu Wang +10 more

Mitochondrial-encoded complex I impairment induces a targetable dependency on aerobic fermentation in Hürthle cell carcinoma of the thyroid

bioRxiv (Cold Spring Harbor Laboratory)(2022)10.1101/2022.08.16.504162

N/A

0DataRank · unranked

2 citations

Vicky Li, Spencer D. Shelton, Jiwoong Kim, Gordon M. Stott, Leonard Μ. Neckers +5 more

Evaluation of the Efficacy of the Hypocretin/orexin Receptor Agonists TAK-925 and ARN-776 in Narcoleptic Orexin/tTA; TetO-DTA Mice

bioRxiv (Cold Spring Harbor Laboratory)(2022)10.1101/2022.12.09.519796

N/A

0DataRank · unranked

0 citations

Alok Ranjan, Ryan K. Tisdale, Shun‐Chieh Ma, Sunmee Park, Meghan Haire +8 more

An oxindole efflux inhibitor potentiates azoles and impairs virulence in the fungal pathogen Candida auris

Nature Communications(2020)10.1038/s41467-020-20183-3

N/A

0DataRank · unranked

71 citations

Kaddy Camara, Martin Daniel-Ivad, Richard Trilles, Sheila Marie Pimentel‐Elardo, Jen Fossen +17 more

Mitochondrial-Encoded Complex I Impairment Induces a Targetable Dependency on Aerobic Fermentation in Hürthle Cell Carcinoma of the Thyroid

Cancer Discovery(2023)10.1158/2159-8290.cd-22-0982

N/A

0DataRank · unranked

18 citations

Vicky Li, Spencer D. Shelton, Jiwoong Kim, Gordon M. Stott, Leonard Μ. Neckers +5 more

Evaluation of the efficacy of the hypocretin/orexin receptor agonists TAK‐925 and ARN‐776 in narcoleptic orexin/tTA; TetO‐DTA mice

Journal of Sleep Research(2023)10.1111/jsr.13839

N/A

0DataRank · unranked

7 citations

Alok Ranjan, Ryan K. Tisdale, Shun‐Chieh Ma, Sunmee Park, Meghan Haire +8 more

Susceptible bacteria survive antibiotic treatment in the mammalian gastrointestinal tract without evolving resistance

Repositorio Institucional UCA (Pontificia Universidad Católica Argentina)(2023)10.1101/2023.01.11.523617

N/A

0DataRank · unranked

0 citations

Parastoo Sabaeifard, Muhammed Sadik Yildiz, Laura Coughlin, Sara Ahmed, Cassie L. Behrendt +11 more

Erratum to: Extended Disease Control with Unconventional Cabozantinib Dose Increase in Metastatic Renal Cell Carcinoma

Kidney Cancer(2023)10.3233/kca-229030

N/A

0DataRank · unranked

0 citations

Roy Elias, Alana Christie, Noelle S. Williams, Iván Pedrosa, Georg A. Bjarnason +2 more

WITHDRAWN: Knockout of HD domain 5’-nucleotidase in T. brucei triggers cell death linked to DNA damage and downregulation of glutamine uptake

bioRxiv (Cold Spring Harbor Laboratory)(2023)10.1101/2023.06.19.545529

N/A

0DataRank · unranked

0 citations

Michael A. Pontikos, Hamid Baniasadi, Noelle S. Williams, Margaret A. Phillips, Yue Wen Deng

The effect of injected dose on localized tumor accumulation and cardiac uptake of doxorubicin in a Vx2 rabbit tumor model using MR-HIFU mild hyperthermia and thermosensitive liposomes

International Journal of Hyperthermia(2020)10.1080/02656736.2020.1812737

N/A

0DataRank · unranked

10 citations

Chenchen Bing, Robert Staruch, Sumbul Shaikh, Michelle Wodzak Staruch, Debra Szczepanski +4 more

Epigenetic modulation through BET bromodomain inhibitors as a novel therapeutic strategy for progranulin-deficient frontotemporal dementia

Scientific Reports(2024)10.1038/s41598-024-59110-7

N/A

0DataRank · unranked

11 citations

Daniel M. Fass, N. Connor Payne, Angela She, Debasis Patnaik, Krista M. Hennig +13 more

Benzoxazole-derivatives enhance progranulin expression and reverse the aberrant lysosomal proteome caused by GRN haploinsufficiency

Nature Communications(2024)10.1038/s41467-024-50076-8

N/A

0DataRank · unranked

8 citations

Charlotte Guhl, Gordon C. Werthmann, Danielle Dixon, Basar Cenik, Yesu Addepalli +9 more

Analogs of the anti-malaria drug mefloquine have broad-spectrum antifungal activity and are efficacious in a model of disseminated Candida auris infection

Antimicrobial Agents and Chemotherapy(2024)10.1128/aac.01301-24

N/A

0DataRank · unranked

1 citations

Marhiah C. Montoya, Xiaoyu Wang, Robert Żarnowski, David R. Andes, Marvin J. Meyers +3 more

Novel orexin receptor agonists based on arene- or pyridine-fused 1,3-dihydro-2H-imidazole-2-imines

Bioorganic & Medicinal Chemistry Letters(2024)10.1016/j.bmcl.2024.129624

N/A

0DataRank · unranked

4 citations

Alok Ranjan, Wei Zhang, Qiren Liang, Karen S. MacMillan, Karen Chapman +6 more

Thiophenyl Derivatives of Nicotinamide Are Metabolized by the NAD Salvage Pathway into Unnatural NAD Derivatives That Inhibit IMPDH and Are Toxic to Peripheral Nerve Cancers

ACS Chemical Biology(2024)10.1021/acschembio.4c00170

N/A

0DataRank · unranked

0 citations

Holly H. Guo, Wentian Wang, Eric Crossley, Giomar Rivera Cancel, Min Fang +7 more

Modular Access to N-SF5 Azetidines

Journal of the American Chemical Society(2025)10.1021/jacs.5c10954

N/A

0DataRank · unranked

28 citations

Chao Hu, Chang Liu, Thomas Lyness, Wenyuan Li, Chen‐Yan Cai +7 more

OAS cross-activates RNase L intercellularly through cell-to-cell transfer of 2-5A to spread innate immunity

Immunity(2025)10.1016/j.immuni.2025.01.016

N/A

0DataRank · unranked

19 citations

Kun Yang, Cong Xing, Kun Song, Heng Lu, Noelle S. Williams +3 more

Structure-guided optimization of small molecules targeting Yck2 as a strategy to combat Candida albicans

Nature Communications(2025)10.1038/s41467-025-57346-z

N/A

0DataRank · unranked

12 citations

Meganathan Nandakumar, Bonnie Yiu, P.J. Stogios, Benjamin G. Strickland, Robert Żarnowski +9 more

Discovery and mechanism of a highly selective, antifungal acetyl-CoA synthetase inhibitor

Nature Communications(2025)10.1038/s41467-025-64183-7

N/A

0DataRank · unranked

2 citations

Katy M. Alden, Jonah Propp, Drashti G. Daraji, Charles L. Lail, Michael E. Heene +10 more

Modular Access to N–SF₅ azetidines

ChemRxiv(2025)10.26434/chemrxiv-2025-q0c07

N/A

0DataRank · unranked

3 citations

Chao Hu, Chang Liu, Thomas Lyness, Wenyuan Li, Chen‐Yan Cai +7 more

Structure-guided optimization of small molecules targeting the yeast casein kinase, Yck2, as a therapeutic strategy to combat Candida albicans

Research Square(2025)10.21203/rs.3.rs-5524306/v1

N/A

0DataRank · unranked

1 citations

Emily Puumala, Meganathan Nandakumar, Bonnie Yiu, P.J. Stogios, Benjamin G. Strickland +9 more

Comparative genomics incorporating translocation renal cell carcinoma mouse model reveals molecular mechanisms of tumorigenesis

Journal of Clinical Investigation(2024)10.1172/jci170559

N/A

0DataRank · unranked

28 citations

Akhilesh Mishra, Alana Christie, Jeffrey Miyata, Deyssy Carrillo, Vanina Toffessi Tcheuyap +19 more

A trimethoprim derivative impedes antibiotic resistance evolution

Nature Communications(2021)10.1038/s41467-021-23191-z

N/A

0DataRank · unranked

100 citations

Yusuf Talha Tamer, Ilona K. Gaszek, Nicole Poulides, Ayesha Ahmed, Xiaoyu Wang +11 more

Loss of wild type KRAS in KRAS lung adenocarcinoma is associated with cancer mortality and confers sensitivity to FASN inhibitors

Lung Cancer(2021)10.1016/j.lungcan.2020.12.032

N/A

0DataRank · unranked

20 citations

Galen F. Gao, John D. Minna, Noelle S. Williams, Kenneth D. Westover, Yan Liu

Polymer microparticles prolong delivery of the 15-PGDH inhibitor SW033291

bioRxiv (Cold Spring Harbor Laboratory)(2021)10.1101/2021.08.15.456403

N/A

0DataRank · unranked

0 citations

Nathan A. Rohner, Julianne Smith, Jessica A. Kilgore, Noelle S. Williams, Sanford D. Markowitz +3 more

KP372-1-Induced AKT Hyperactivation Blocks DNA Repair to Synergize With PARP Inhibitor Rucaparib via Inhibiting FOXO3a/GADD45α Pathway

Frontiers in Oncology(2022)10.3389/fonc.2022.976292

N/A

0DataRank · unranked

6 citations

Yingchun Liu, Xiaolin Su, Jiangwei Wang, Ye Zhao, Soumya Tumbath +9 more

Development of a biomarker to monitor target engagement after treatment with dihydroorotate dehydrogenase inhibitors

Biochemical Pharmacology(2022)10.1016/j.bcp.2022.115237

N/A

0DataRank · unranked

2 citations

Christopher Leija, Zhiyu Zhao, Xiaoyu Wang, Jessica A. Kilgore, Belén Tornesi +4 more