Tomasz Cierpicki

ORCID: 0000-0003-2058-0658

Biochemistry, Genetics and Molecular BiologyMedicine

Pilot corpus only

This score is computed over theSindex pilot corpus and does not cover the full scientific literature. Scores are relative to papers we have ingested — papers, authors, and institutions outside the pilot are not represented. Methodology.

Top 100%percentile

0Author DataRank

Indexed papers

0in pilot corpus

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Papers

Driven by 20 papers. Top paper: “Small-molecule inhibitors targeting Polycomb repressive complex 1 RING domain”.

Small-molecule inhibitors targeting Polycomb repressive complex 1 RING domain

Nature Chemical Biology(2021)10.1038/s41589-021-00815-5

N/A

1.8DataRank · unranked

67 citations

Weijiang Ying, Felicia Gray, Yiwu Yao, Miranda L. Simes, Qingjie Zhao +20 more

Drug-resistant menin variants retain high binding affinity and interactions with MLL1

Journal of Biological Chemistry(2024)10.1016/j.jbc.2024.107777

N/A

0.609DataRank · unranked

16 citations

Bradley Clegg, Jolanta Grembecka, Tomasz Cierpicki, Joshua Ray

Discovery of first-in-class inhibitors of ASH1L histone methyltransferase with anti-leukemic activity

Nature Communications(2021)10.1038/s41467-021-23152-6

N/A

0.568DataRank · unranked

43 citations

Jing Deng, Hao Li, Hongzhi Miao, Dmitry Borkin, Trupta Purohit +25 more

EWS-FLI1 and Menin Converge to Regulate ATF4 Activity in Ewing Sarcoma

Molecular Cancer Research(2021)10.1158/1541-7786.mcr-20-0679

N/A

0.490DataRank · unranked

14 citations

April A. Apfelbaum, Allegra G. Hawkins, Laurie K. Svoboda, Abhijay Kumar, Ramón Ocádiz-Ruiz +11 more

Increased slow dynamics defines ligandability of BTB domains

Nature Communications(2022)10.1038/s41467-022-34599-6

N/A

0DataRank · unranked

7 citations

Brian M. Linhares, Megan Borregard, Iwona Czaban, Jolanta Grembecka, Mariusz Jaremko +3 more

2-Aminobenzothiazoles in anticancer drug design and discovery

Bioorganic Chemistry(2023)10.1016/j.bioorg.2023.106477

N/A

0DataRank · unranked

50 citations

Tomasz Cierpicki, Jolanta Grembecka, G. Huang

Applications of oxetanes in drug discovery and medicinal chemistry

European Journal of Medicinal Chemistry(2023)10.1016/j.ejmech.2023.115802

N/A

0DataRank · unranked

28 citations

Devon G. Hucek, Tomasz Cierpicki, Jolanta Grembecka, G. Huang

Garcinolic Acid Distinguishes Between GACKIX Domains and Modulates Interaction Networks

ChemBioChem(2023)10.1002/cbic.202300439

N/A

0DataRank · unranked

4 citations

Stephen T. Joy, Omari J. Baruti, Matthew S. Beyersdorf, Matthew J. Henley, Samantha N. De Salle +6 more

A lipopeptidomimetic of transcriptional activation domains selectively disrupts Med25 PPIs

bioRxiv (Cold Spring Harbor Laboratory)(2023)10.1101/2023.03.24.534168

N/A

0DataRank · unranked

0 citations

Estefanía Martínez Valdivia, Matthew S. Beyersdorf, Clint S. Regan, Mónica Rivas, Sofía D. Merajver +3 more

Data from Mutant NPM1 Hijacks Transcriptional Hubs to Maintain Pathogenic Gene Programs in Acute Myeloid Leukemia

(2023)10.1158/2159-8290.c.6549829.v1

N/A

0DataRank · unranked

0 citations

Dandan Fan, Qinyu Han, Yiman Liu, Hongzhi Miao, Xinyu Wang +12 more

Thioamides in medicinal chemistry and as small molecule therapeutic agents

European Journal of Medicinal Chemistry(2024)10.1016/j.ejmech.2024.116732

N/A

0DataRank · unranked

33 citations

Tomasz Cierpicki, Jolanta Grembecka, G. Huang

Combination of menin and kinase inhibitors as an effective treatment for leukemia with NUP98 translocations

Leukemia(2024)10.1038/s41375-024-02312-9

N/A

0DataRank · unranked

22 citations

Dong Chen, James Ropa, Trupta Purohit, EunGi Kim, Maria‐Luisa Sulis +4 more

Structure-Based Development of Novel Spiro-Piperidine ASH1L Inhibitors

Journal of Medicinal Chemistry(2024)10.1021/acs.jmedchem.4c01673

N/A

0DataRank · unranked

5 citations

Rhiannon Stevens, Devon G. Hucek, Trupta Purohit, Shuangjiang Li, Hongzhi Miao +10 more

A Lipopeptidomimetic of Transcriptional Activation Domains Selectively Disrupts the Coactivator Med25 Protein–Protein Interactions

Angewandte Chemie International Edition(2024)10.1002/anie.202400781

N/A

0DataRank · unranked

5 citations

Estefanía Martínez Valdivia, Matthew S. Beyersdorf, Clint S. Regan, Mónica Rivas, Katherine A. Hebert +4 more

Unlocking the potential of the thioamide group in drug design and development

Future Medicinal Chemistry(2024)10.1080/17568919.2024.2435245

N/A

0DataRank · unranked

5 citations

Tomasz Cierpicki, Jolanta Grembecka, G. Huang

Menin inhibitor MI-3454 induces remission in MLL1-rearranged and NPM1-mutated models of leukemia.

Journal of Clinical Investigation(2020)10.1172/jci129126

N/A

0DataRank · unranked

142 citations

Hongzhi Miao, Katarzyna Kempińska, Tao Wu, Trupta Purohit, Eungi Kim +30 more

A Lipopeptidomimetic of Transcriptional Activation Domains Selectively Disrupts the Coactivator Med25 Protein–Protein Interactions

Angewandte Chemie(2024)10.1002/ange.202400781

N/A

0DataRank · unranked

0 citations

Estefanía Martínez Valdivia, Matthew S. Beyersdorf, Clint S. Regan, Mónica Rivas, Katherine A. Hebert +4 more

Covalent inhibition of NSD1 histone methyltransferase

Nature Chemical Biology(2020)10.1038/s41589-020-0626-6

N/A

0DataRank · unranked

87 citations

Christina A. Howard, Sergei Zari, Hyo Je Cho, Shirish Shukla, Hao Li +16 more

Unexpected Specificity within Dynamic Transcriptional Protein-Protein Complexes

bioRxiv (Cold Spring Harbor Laboratory)(2020)10.1101/2020.05.29.124271

N/A

0DataRank · unranked

6 citations

Brian M. Linhares, Brittany S. Morgan, Tomasz Cierpicki, Carol A. Fierke, Anna K. Mapp +1 more

Chemical validation of a druggable site on Hsp27/HSPB1 using in silico solvent mapping and biophysical methods

Bioorganic & Medicinal Chemistry(2021)10.1016/j.bmc.2020.115990

N/A

0DataRank · unranked

7 citations

Oleta T. Johnson, Phani Ghanakota, Jennifer N. Rauch, Delaney Osborn, Taiasean Wu +4 more