Sumedha Gunewardena

ORCID: 0000-0003-2097-135X

Also affiliated with University of Kansas Medical Center

Biochemistry, Genetics and Molecular BiologyMedicine

Pilot corpus only

This score is computed over theSindex pilot corpus and does not cover the full scientific literature. Scores are relative to papers we have ingested — papers, authors, and institutions outside the pilot are not represented. Methodology.

Top 5%percentile

0.526Author DataRank

Indexed papers

1in pilot corpus

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Why this DataRank?

An author's DataRank is the sum of the DataRanks of all 1 indexed paper attributed to them. A prolific author with many moderate-impact papers can outrank one with a single high-impact paper.

Author scores recompute whenever paper DataRanks are refreshed, so this number lags the underlying paper scores by at most one batch run.

Read the full methodology →

The highest-impact dataset this researcher has shared, ranked by DataRank — the single contribution doing the most to lift their data-sharing standing.

Landscape of Double-Stranded DNA Breaks in Postmortem Brains from Alzheimer’s Disease and Non-Demented Individuals

Journal of Alzheimer s Disease(2023)10.3233/jad-230316

Top 37%

0.526DataRank

Top 37%18 citations

Yan Liu, Ming Huang, Sumedha Gunewardena, Mohammad Haeri, Russell H. Swerdlow +2 more

Papers

Driven by 57 papers — median percentile 63. Top paper: “An FGF15/19-TFEB regulatory loop controls hepatic cholesterol and bile acid homeostasis”.

An FGF15/19-TFEB regulatory loop controls hepatic cholesterol and bile acid homeostasis

Nature Communications(2020)10.1038/s41467-020-17363-6

N/A

0.689DataRank · unranked

98 citations

Sumedha Gunewardena, Feng Li, David Matye, Cheng Chen, Xiaojuan Chao +7 more

Comparison of liver regeneration after partial hepatectomy and acetaminophen-induced acute liver failure: A global picture based on transcriptome analysis

Food and Chemical Toxicology(2020)10.1016/j.fct.2020.111186

N/A

0.654DataRank · unranked

21 citations

Sumedha Gunewardena, Genea Edwards, Udayan Apte, Bharat Bhushan

RNA Sequencing of Human Peripheral Nerve in Response to Injury: Distinctive Analysis of the Nerve Repair Pathways

Cell Transplantation(2020)10.1177/0963689720926157

N/A

0.557DataRank · unranked

40 citations

Jorge E. Quintero, Nader El Seblani, Eric M. Blalock, Sumedha Gunewardena, Steven M. Shapiro +7 more

Landscape of Double-Stranded DNA Breaks in Postmortem Brains from Alzheimer’s Disease and Non-Demented Individuals

Journal of Alzheimer s Disease(2023)10.3233/jad-230316

Top 37%

0.526DataRank

Top 37%18 citations

Yan Liu, Ming Huang, Sumedha Gunewardena, Mohammad Haeri, Russell H. Swerdlow +2 more

TFEB regulates sulfur amino acid and coenzyme A metabolism to support hepatic metabolic adaptation and redox homeostasis

Nature Communications(2022)10.1038/s41467-022-33465-9

N/A

0.505DataRank · unranked

28 citations

Sumedha Gunewardena, Jianglei Chen, Huaiwen Wang, Yifeng Wang, Mohammad Nazmul Hasan +9 more

Regulation of Liver Regeneration by Hepatocyte O-GlcNAcylation in Mice

Cellular and Molecular Gastroenterology and Hepatology(2022)10.1016/j.jcmgh.2022.01.014

N/A

0.500DataRank · unranked

27 citations

Steven R. McGreal, David S. Umbaugh, Wendena S. Parkes, Manasi Kotulkar, Sarah Abernathy +9 more

Transcriptional metabolic reprogramming implements meiotic fate decision in mouse testicular germ cells

Cell Reports(2023)10.1016/j.celrep.2023.112749

N/A

0.449DataRank · unranked

19 citations

Yan Liu, Froylan Sosa, Sumedha Gunewardena, Peter A. Crawford, Amanda C. Zielen +3 more

Regulation of Liver Regeneration by hepatocyte O-GlcNAcylation in mice

bioRxiv (Cold Spring Harbor Laboratory)(2021)10.1101/2021.10.14.464401

N/A

0.269DataRank · unranked

5 citations

Steven R. McGreal, David S. Umbaugh, Wendena S. Parkes, Manasi Kotulkar, Sarah Abernathy +9 more

Notch3 deletion regulates HIV-1 gene expression and systemic inflammation to ameliorate chronic kidney disease

Disease Models & Mechanisms(2025)10.1242/dmm.052056

N/A

0.208DataRank · unranked

3 citations

Nicole G. Sommer, Mercedes B. Mcgonigle, Anil Kumar Ram, Sireesha Yerrathota, Henrietta Ehirim +15 more

Transcriptomic data showing differentially expressed genes between Notch3 and Notch4 deleted mice

Data in Brief(2021)10.1016/j.dib.2021.106873

N/A

0.165DataRank · unranked

2 citations

Sireesha Yerrathota, Mackenzie Thornton, Sumedha Gunewardena, Madhulika Sharma

Targeting FGFR Attenuates Tumor Growth in an Anal Squamous Cell Carcinoma Patient Derived Xenograft Model

Molecular Carcinogenesis(2025)10.1002/mc.23919

N/A

0.165DataRank · unranked

2 citations

Athena Golfinos-Owens, Naren Raja, Levi Arnold, Pachiappan Arjunan, John Ashcraft +7 more

HCC-derived SNU cell lines as model systems to study HBV life cycle

Journal of Virology(2025)10.1128/jvi.01144-25

N/A

0.104DataRank · unranked

1 citations

Oleksandra Chazova, Sumedha Gunewardena, Severin O. Gudima, Igor Zaiets

The Tie2 antagonist rebastinib reduces ovarian cancer growth in a syngeneic murine model

BMC Cancer(2025)10.1186/s12885-025-13640-z

N/A

0.104DataRank · unranked

1 citations

Katherine F. Roby, Harsh B. Pathak, Andrew K. Godwin, Sumedha Gunewardena, Dineo Khabele +1 more

Loss of PRICKLE1 leads to subfertility, aberrant extracellular matrix and abnormal myometrial architecture in mice

Reproduction(2024)10.1530/rep-24-0344

N/A

0.104DataRank · unranked

1 citations

Sornakala Ganeshkumar, Sumedha Gunewardena, Vargheese M. Chennathukuzhi, Emily Roberts

Loss of REST in breast cancer promotes tumor progression through estrogen sensitization, MMP24 and CEMIP overexpression

BMC Cancer(2022)10.1186/s12885-022-09280-2

N/A

0DataRank · unranked

31 citations

Aditya M. Vargheese, Sumedha Gunewardena, Raeann M. Shimak, Sornakala Ganeshkumar, Easwari Kumaraswamy +3 more

GenX induces fibroinflammatory gene expression in primary human hepatocytes

Toxicology(2022)10.1016/j.tox.2022.153259

N/A

0DataRank · unranked

30 citations

Kaitlyn K. Venneman, Sumedha Gunewardena, Udayan Apte, Dakota R. Robarts

The START domain mediates Arabidopsis GLABRA2 dimerization and turnover independently of homeodomain DNA binding

PLANT PHYSIOLOGY(2022)10.1093/plphys/kiac383

N/A

0DataRank · unranked

23 citations

Bibek Subedi, Aashima Khosla, Erika M. Begler, Preston M. Stephens, Adara L. Warner +5 more

CCN5 Activation by free or encapsulated-EGCG is required to Render Triple-negative breast cancer cell Viability and Tumor Progression

(2022)10.22541/au.164864795.55156696/v1

N/A

0DataRank · unranked

20 citations

Inamul Haque, Priyanka Ray, Arnab Ghosh, Debasmita Dutta, Mohiuddin Quadir +7 more

Loss of the repressor REST affects progesterone receptor function and promotes uterine leiomyoma pathogenesis

bioRxiv (Cold Spring Harbor Laboratory)(2022)10.1101/2022.04.11.487902

N/A

0DataRank · unranked

2 citations

Faezeh Koohestani, Michelle M. McWilliams, Sornakala Ganeshkumar, Sumedha Gunewardena, Amanda Graham +3 more

Doublecortin-like kinase 1 is a therapeutic target in squamous cell carcinoma

bioRxiv (Cold Spring Harbor Laboratory)(2022)10.1101/2022.05.26.493670

N/A

0DataRank · unranked

2 citations

Levi Arnold, Prasad Dandawate, Brendan M. Ottemann, Vusala Snyder, Sivapriya Ponnurangam +20 more

Hippo Signaling Cofactor, WWTR1, at the Crossroads of Human Trophoblast Progenitor Self-Renewal and Differentiation

bioRxiv (Cold Spring Harbor Laboratory)(2022)10.1101/2022.03.06.483207

N/A

0DataRank · unranked

1 citations

Abhik Saha, Ananya Ghosh, Namrata Roy, Ram Kumar, Gudrun Meinhardt +6 more

Integrated epigenome and transcriptome analysis of normal and arrested meiotic initiation during mouse spermatogenesis

bioRxiv (Cold Spring Harbor Laboratory)(2022)10.1101/2022.02.18.481086

N/A

0DataRank · unranked

0 citations

Sumedha Gunewardena, Ning Wang, Xiaoyu Zhang

HIF1A modulate glycolysis function to governs mouse ovarian microenvironment metabolic plasticity in aging single cell resolution

bioRxiv (Cold Spring Harbor Laboratory)(2022)10.1101/2022.03.01.481557

N/A

0DataRank · unranked

0 citations

Sumedha Gunewardena, Yan Liu, Ning Wang, Xiaoyu Zhang

Exploring Whether Iron Sequestration within the CNS of Patients with Alzheimer’s Disease Causes a Functional Iron Deficiency That Advances Neurodegeneration

Brain Sciences(2023)10.3390/brainsci13030511

N/A

0DataRank · unranked

20 citations

Sheila Tsau, Sumedha Gunewardena, Steven M. LeVine

Sera of Individuals Chronically Infected with Hepatitis B Virus (HBV) Contain Diverse RNA Types Produced by HBV Replication or Derived from Integrated HBV DNA

Journal of Virology(2023)10.1128/jvi.01950-22

N/A

0DataRank · unranked

19 citations

Sumedha Gunewardena, Stephan Menne, Steven A. Weinman, Severin O. Gudima, Igor Zaiets

Identification of follicle‐stimulating hormone‐responsive genes in Sertoli cells during early postnatal mouse testis development

Andrology(2023)10.1111/andr.13459

N/A

0DataRank · unranked

9 citations

Zhenghui Liu, Mark Larsen, Richard Hastings, Sumedha Gunewardena, T. Rajendra Kumar +1 more

LH/hCG Regulation of Circular RNA in Mural Granulosa Cells during the Periovulatory Period in Mice

International Journal of Molecular Sciences(2023)10.3390/ijms241713078

N/A

0DataRank · unranked

5 citations

Wei‐Ting Hung, Nanda Kumar Yellapu, Sumedha Gunewardena, Lane K. Christenson, V. Praveen Chakravarthi

A method for temporal-spatial multivariate genomic analysis of acute wound healing via tissue stratification: a porcine negative pressure therapy pilot study

Frontiers in Molecular Medicine(2023)10.3389/fmmed.2023.1195822

N/A

0DataRank · unranked

1 citations

Sumedha Gunewardena, Richard Korentager, David S. Zamierowski, Jennifer L. Robinson, Adam J. Mellott +1 more

Identifying Human Specific Adverse Outcome Pathways of Per- and Polyfluoroalkyl Substances Using Liver-Chimeric Humanized Mice

bioRxiv (Cold Spring Harbor Laboratory)(2023)10.1101/2023.02.01.526711

N/A

0DataRank · unranked

4 citations

Diego Paine‐Cabrera, Manasi Kotulkar, Kaitlyn K. Venneman, Sumedha Gunewardena, J. Christopher Corton +5 more

Endometrial cyclin A2 deficiency is associated with human female infertility and is recapitulated in a conditional knockout mouse model

bioRxiv (Cold Spring Harbor Laboratory)(2023)10.1101/2023.06.16.545284

N/A

0DataRank · unranked

0 citations

Katelyn Shumacher, Amanda Graham, Sumedha Gunewardena, Courtney Marsh, Michael Lydic +3 more

Notch3 deletion regulates HIV-1 gene expression and systemic inflammation to ameliorate chronic kidney disease

The Medicine Forum(2023)10.1101/2023.09.12.557484

N/A

0DataRank · unranked

0 citations

Nicole G. Sommer, Mercedes B. Mcgonigle, Anil Kumar Ram, Sireesha Yerrathota, Henrietta Ehirim +15 more

Resistance exercise in early-stage ALS patients, ALSFRS-R, Sickness Impact Profile ALS-19, and muscle transcriptome: a pilot study

Scientific Reports(2024)10.1038/s41598-024-72355-6

N/A

0DataRank · unranked

9 citations

Jason Rucker, Tomoki Nakano, Kotaro Takeno, Jeffrey Statland, Mamatha Pasnoor +12 more

Selective targeting of IRAK1 attenuates low molecular weight hyaluronic acid-induced stemness and non-canonical STAT3 activation in epithelial ovarian cancer

Cell Death and Disease(2024)10.1038/s41419-024-06717-3

N/A

0DataRank · unranked

5 citations

Prasad Dandawate, Sumedha Gunewardena, Obdulia Covarrubias‐Zambrano, Katherine F. Roby, Dineo Khabele +8 more

Uterine cyclin A2–deficient mice as a model of female early pregnancy loss

Journal of Clinical Investigation(2024)10.1172/jci163796

N/A

0DataRank · unranked

7 citations

Katelyn Schumacher, Amanda Graham, Sumedha Gunewardena, Courtney Marsh, Michael Lydic +3 more

Analysis of MicroRNA Cargo in Circulating Extracellular Vesicles from HIV-Infected Individuals with Pulmonary Hypertension

Cells(2024)10.3390/cells13110886

N/A

0DataRank · unranked

2 citations

Sumedha Gunewardena, Alison Morris, Matthias Clauss, Navneet K. Dhillon, Aatish Mahajan

A Single Trophoblast Layer Acts as the Gatekeeper at the Endothelial-Hematopoietic Crossroad in the Placenta

bioRxiv (Cold Spring Harbor Laboratory)(2024)10.1101/2024.07.12.603303

N/A

0DataRank · unranked

1 citations

Ananya Ghosh, Ram Kumar, Ram Parikshan Kumar, Soma Ray, Sumedha Gunewardena +8 more

Loss of PRICKLE1 in the myometrium leads to reduced fertility, abnormal myometrial architecture, and aberrant extracellular matrix deposition in mice

bioRxiv (Cold Spring Harbor Laboratory)(2024)10.1101/2024.09.12.612708

N/A

0DataRank · unranked

0 citations

Sornakala Ganeshkumar, Sumedha Gunewardena, Vargheese M. Chennathukuzhi, Emily Roberts

Modulation of β-Catenin promotes WNT expression in macrophages and mitigates intestinal injury

Cell Communication and Signaling(2025)10.1186/s12964-025-02065-7

N/A

0DataRank · unranked

11 citations

Payel Bhanja, Ryan Zitter, Sumedha Gunewardena, Rajeev Badkul, Subhrajit Saha +1 more

TRIM16 mediates secretory autophagy in head and neck cancer-associated fibroblasts

Autophagy(2025)10.1080/15548627.2025.2508064

N/A

0DataRank · unranked

4 citations

Bailey Pickard, Avisha Pandey, Marrion Yap, J. K. Opara, Levi Arnold +14 more

Loss of PRICKLE1 leads to abnormal endometrial epithelial architecture, decreased embryo implantation, and reduced fertility in mice

PNAS Nexus(2025)10.1093/pnasnexus/pgaf024

N/A

0DataRank · unranked

3 citations

Aishwarya V. Bhurke, Sornakala Ganeshkumar, Sumedha Gunewardena, Ripla Arora, Vargheese M. Chennathukuzhi +1 more

Pirfenidone treatment attenuates fibrosis in autosomal dominant polycystic kidney disease

bioRxiv (Cold Spring Harbor Laboratory)(2025)10.1101/2025.08.25.672225

N/A

0DataRank · unranked

1 citations

Abeda Jamadar, Meekha M. Varghese, Haichun Yang, Sumedha Gunewardena, Darren P Wallace +2 more

Regulatory Role for Tumor Suppressor REST on Estrogen Receptor ( ESR1 ) Expression and Leiomyoma Pathophysiology

bioRxiv (Cold Spring Harbor Laboratory)(2025)10.1101/2025.08.29.673140

N/A

0DataRank · unranked

0 citations

Sumedha Gunewardena, Ashley S. Cloud, Sornakala Ganeshkumar, Vargheese M. Chennathukuzhi, Skylar G. Bird

Liver Macrophage Changes during Early Adaptation to Alcohol Exposure

American Journal Of Pathology(2025)10.1016/j.ajpath.2025.10.004

N/A

0DataRank · unranked

0 citations

Janice Nullan Averilla, Zhuan Li, Priyanka Ghosh, Sheetalnath Rooge, Isabel Aranzazu Pulido Ruiz +6 more

Regulatory role for tumor suppressor REST on estrogen receptor (ESR1) expression and leiomyoma pathophysiology

Journal of Biological Chemistry(2025)10.1016/j.jbc.2025.111017

N/A

0DataRank · unranked

0 citations

Sumedha Gunewardena, Ashley S. Cloud, Sornakala Ganeshkumar, Vargheese M. Chennathukuzhi, Skylar G. Bird

Transplacental arsenic exposure produced 5-methylcytosine methylation changes and aberrant microRNA expressions in livers of male fetal mice

Toxicology(2020)10.1016/j.tox.2020.152409

N/A

0DataRank · unranked

21 citations

Sumedha Gunewardena, Julia Yue Cui, Curtis D. Klaassen, Brian N. Chorley, J. Christopher Corton +1 more

Atypical protein kinase C iota (PKCλ/ι) ensures mammalian development by establishing the maternal–fetal exchange interface

Proceedings of the National Academy of Sciences(2020)10.1073/pnas.1920201117

N/A

0DataRank · unranked

26 citations

Pratik Home, Avishek Ganguly, Soma Ray, Ananya Ghosh, Md. Rashedul Islam +7 more

Nutrient restriction, inducer of yeast meiosis, induces meiotic initiation in mammals

bioRxiv (Cold Spring Harbor Laboratory)(2020)10.1101/2020.05.15.074542

N/A

0DataRank · unranked

1 citations

Sumedha Gunewardena, Ning Wang, Xiaoyu Zhang

Teratogenic Drug Topiramate Upregulates TGFβ1 and SOX9 Expression in Primary Palatal Mesenchyme Cells

bioRxiv (Cold Spring Harbor Laboratory)(2020)10.1101/2019.12.31.892042

N/A

0DataRank · unranked

0 citations

Jeremy P. Goering, Adam J. Olm-Shipman, Lauren A. Hipp, Nicholas J. Ernst, Nathan R. Wilson +4 more

Nutrient restriction, inducer of yeast meiosis, induces mammalian meiotic initiation

Research Square(2020)10.21203/rs.3.rs-35893/v1

N/A

0DataRank · unranked

0 citations

Sumedha Gunewardena, Ning Wang, Xiaoyu Zhang

Nutrient restriction synergizes with retinoic acid to induce mammalian meiotic initiation in vitro

Nature Communications(2021)10.1038/s41467-021-22021-6

N/A

0DataRank · unranked

41 citations

Sumedha Gunewardena, Ning Wang, Xiaoyu Zhang

Disrupting interferon-alpha and NF-kappaB crosstalk suppresses IFITM1 expression attenuating triple-negative breast cancer progression

Cancer Letters(2021)10.1016/j.canlet.2021.05.006

N/A

0DataRank · unranked

34 citations

Eric S. Geanes, Asona Lui, Anuradha Roy, Sean M. Holloran, Sumedha Gunewardena +4 more

Anti-epileptic drug topiramate upregulates TGFβ1 and SOX9 expression in primary embryonic palatal mesenchyme cells: Implications for teratogenicity

PLoS ONE(2021)10.1371/journal.pone.0246989

N/A

0DataRank · unranked

13 citations

Jeremy P. Goering, Adam J. Olm-Shipman, Lauren A. Hipp, Nicholas J. Ernst, Nathan R. Wilson +4 more

Forkhead box F1 induces columnar phenotype and epithelial-to-mesenchymal transition in esophageal squamous cells to initiate Barrett's like metaplasia

Laboratory Investigation(2021)10.1038/s41374-021-00534-4

N/A

0DataRank · unranked

6 citations

Jianping Zhou, Pi Liu, Manling Huang, Sumedha Gunewardena, Sharad C. Mathur +5 more

Histone lysine demethylase 4B regulates general and unique gene expression signatures in hypoxic cancer cells

MedComm(2021)10.1002/mco2.85

N/A

0DataRank · unranked

10 citations

Yang Meng, Lingli Wang, Sumedha Gunewardena, Sicheng Liu, Junhong Han +2 more

Loss of REST in Breast Cancer Promotes Tumor Progression Through Estrogen Sensitization, MMP24 and CEMIP Overexpression.

Research Square(2021)10.21203/rs.3.rs-345857/v1

N/A

0DataRank · unranked

1 citations

Aditya M. Vargheese, Sumedha Gunewardena, Raeann M. Shimak, Sornakala Ganeshkumar, Easwari Kumaraswamy +3 more

Hippo signaling cofactor, WWTR1, at the crossroads of human trophoblast progenitor self-renewal and differentiation

Proceedings of the National Academy of Sciences(2022)10.1073/pnas.2204069119

N/A

0DataRank · unranked

42 citations

Abhik Saha, Ananya Ghosh, Namrata Roy, Ram Kumar, Gudrun Meinhardt +6 more

Loss of the repressor REST affects progesterone receptor function and promotes uterine leiomyoma pathogenesis

Proceedings of the National Academy of Sciences(2022)10.1073/pnas.2205524119

N/A

0DataRank · unranked

23 citations

Faezeh Koohestani, Michelle M. McWilliams, Sornakala Ganeshkumar, Sumedha Gunewardena, Amanda Graham +3 more

Sumedha Gunewardena

Indexed papers

Top data-sharing exemplar

Papers