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Comparison of liver regeneration after partial hepatectomy and acetaminophen-induced acute liver failure: A global picture based on transcriptome analysis

Food and Chemical Toxicology(2020)10.1016/j.fct.2020.111186Source: DataRank Database

Comparison of liver regeneration after partial hepatectomy and acetaminophen-induced acute liver failure: A global picture based on transcriptome analysis is a research paper published in Food and Chemical Toxicology (2020). On theSindex it has a DataRank of 0.654. It has been cited 21 times, with 12 citing works in its 1-hop citation network.

N/A

0.654DataRank · unranked

Scored on demand from live citation data

Open Access21 citations · 12 citing works in its network

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›Methodology & internals

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Pipeline:MetadataData-paper checkEnrichmentCitation networkScoring

Enrichment:Funding (9 grants)Impact (FWCI 1.02)OA: greenTopics (70)IDs (PubMed, PMC, OpenAlex)SDGs (1)

FAIR Checklist

Context only (not used in score)

Findable (1/2)

Has DOI

Accessible (1/2)

Open Access

Interoperable (0/2)

Reusable (0/3)

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DataRank Breakdown

Base Score 71%Citation Network 29%

Base Score Contribution

0.464

From this paper's citation signal

Citation Network Contribution

0.190

From 8 citing papers with measurable signal

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Top 5 citers driving the network score

Ranked by each citer's contribution to N(p) — log1p(C_q) divided by its reference count — out of 12 citers.

Integration of transcriptomics and metabolomics confirmed hepatoprotective effects of steamed shoot extracts of ginseng (Panax ginseng C.A. Meyer) on toxicity caused by overdosed acetaminophen
Biomedicine & Pharmacotherapy202118 citations57 referencesContributes 0.052
Neddylation inhibition prevents acetaminophen-induced liver damage by enhancing the anabolic cardiolipin pathway
Cell Reports Medicine202411 citations61 referencesContributes 0.041
Novel Optical Criteria and Mechanisms of Critical Decline in Liver Regenerative Potential
Cells20243 citations41 referencesContributes 0.034
Role of Noncoding RNAs in Acetaminophen-Induced Liver Injury
Gene Expression20216 citations58 referencesContributes 0.034
Biomarkers in liver regeneration
Clinica Chimica Acta20254 citations61 referencesContributes 0.026

Authors (4)

Sumedha Gunewardena ORCID,Genea Edwards ORCID,Udayan Apte ORCID,Bharat Bhushan ORCID

Live enrichment

PubMed:32045647 PMC:PMC7687355 OpenAlex:https://openalex.org/W3005072553

National Institutes of Health

Grant: DKR0198414

National Institutes of Health

Grant: P20 RR021940

Helmholtz-Gemeinschaft

Grant: 6.337

Helmholtz-Gemeinschaft

Grant: 1.72 \u00D7 10\u221231

Helmholtz-Gemeinschaft

Grant: 1.26 \u00D7 10\u221232

NIDDK NIH HHS

Grant: R01 DK098414

National Institutes of Health

Grant: 5P20RR021940-04

CORE F CENTER JOINT PROJECTS

American Association for the Study of Liver Diseases

American Liver Foundation

FWCI

1.02

Citation Percentile

0.8%

Citation Trend

2020

2021

2022

2023

2024

2025

2026

greenLicense: Elsevier TDM

repositoryhttps://www.ncbi.nlm.nih.gov/pmc/articles/7687355

publisherhttps://api.elsevier.com/content/article/PII:S0278691520300740?httpAccept=text/xml

publisherhttps://api.elsevier.com/content/article/PII:S0278691520300740?httpAccept=text/plain

journalhttps://doi.org/10.1016/j.fct.2020.111186

Fields of Study

Liver physiology and pathologyDrug-Induced Hepatotoxicity and ProtectionOrgan Transplantation Techniques and Outcomes0301 basic medicine03 medical and health sciencesAcetaminophenAnimalsCell ProliferationChemical and Drug Induced Liver InjuryEpidermal Growth FactorGene Expression ProfilingHepatectomyHepatocytesLiverLiver Failure, AcuteLiver RegenerationMaleMiceMice, Inbred C57BLTumor Necrosis Factor-alphaVascular Endothelial Growth Factor A

MeSH Terms

AcetaminophenAnimalsEpidermal Growth FactorHepatectomyLiverLiver RegenerationMaleMice, Inbred C57BLTumor Necrosis Factor-alphaLiver Failure, AcuteGene Expression ProfilingHepatocytesVascular Endothelial Growth Factor ACell ProliferationMiceChemical and Drug Induced Liver Injury

Keywords

Liver regenerationAcetaminophenRegeneration (biology)TranscriptomeHepatocyteLiver injuryHepatectomyPharmacologyBiologyChemistryMedicineCell biologyGene expressionGeneBiochemistrySurgeryEpidermal growth factor (EGF)Vascular endothelial growth factor (VEGF)Hepatocyte Growth Factor (Hgf)Tumor Necrosis Factor Alpha (Tnfα) And Interleukin 6 (Il6)MaleVascular Endothelial Growth Factor AEpidermal Growth FactorTumor Necrosis Factor-alphaGene Expression ProfilingLiver Failure, AcuteMice, Inbred C57BLMiceLiverHepatocytesAnimalsChemical and Drug Induced Liver InjuryCell Proliferation

Sustainable Development Goals

SDG 0: Good health and well-being