🏆 Finalist — NIH Data Sharing Index (“S-Index”) Challenge

Nicholas J. Kapolka

University of North Carolina at Chapel Hill

ORCID: 0000-0003-2223-8207

Also affiliated with Zen Bio (United States)

Biochemistry, Genetics and Molecular BiologyNeuroscienceChemistry

Pilot corpus only

This score is computed over theSindex pilot corpus and does not cover the full scientific literature. Scores are relative to papers we have ingested — papers, authors, and institutions outside the pilot are not represented. Methodology.

Top 100%percentile

0Author DataRank

Indexed papers

1in pilot corpus

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Why this DataRank?

An author's DataRank is the sum of the DataRanks of all 1 indexed paper attributed to them. A prolific author with many moderate-impact papers can outrank one with a single high-impact paper.

Author scores recompute whenever paper DataRanks are refreshed, so this number lags the underlying paper scores by at most one batch run.

Read the full methodology →

Papers

Driven by 11 papers. Top paper: “AlphaFold2 structures guide prospective ligand discovery”.

AlphaFold2 structures guide prospective ligand discovery

Science(2024)10.1126/science.adn6354

N/A

3.3DataRank · unranked

151 citations

Nicholas J. Kapolka, Ryan H. Gumpper, Assaf Alon, Liang Wang, Manish K. Jain +16 more

Predictable cholesterol binding sites in GPCRs lack consensus motifs

Structure(2021)10.1016/j.str.2021.01.004

N/A

0.663DataRank · unranked

82 citations

Jacob B. Rowe, Nicholas J. Kapolka, Daniel G. Isom, Geoffrey J. Taghon

Structure-guided design of a peripherally restricted chemogenetic system

Cell(2024)10.1016/j.cell.2024.11.001

N/A

0.385DataRank · unranked

12 citations

B. Krumm, Adrien Tassou, Matan Geron, Jeffrey F. DiBerto, Nicholas J. Kapolka +15 more

Cholesterol Binds G Protein‐coupled Receptors in Conserved Sites Without Recurring Motifs

The FASEB Journal(2021)10.1096/fasebj.2021.35.s1.03682

N/A

0DataRank · unranked

0 citations

Jacob B. Rowe, Nicholas J. Kapolka, Daniel G. Isom, Geoffrey J. Taghon

AlphaFold2 structures template ligand discovery

bioRxiv (Cold Spring Harbor Laboratory)(2023)10.1101/2023.12.20.572662

N/A

0DataRank · unranked

19 citations

Nicholas J. Kapolka, Ryan H. Gumpper, Assaf Alon, Liang Wang, Manish K. Jain +15 more

Proton-gated coincidence detection is a common feature of GPCR signaling

bioRxiv (Cold Spring Harbor Laboratory)(2021)10.1101/2021.01.08.425945

N/A

0DataRank · unranked

1 citations

Jacob B. Rowe, Geoffrey J. Taghon, William M. Morgan, Corin R. O’Shea, Daniel G. Isom +1 more

A neurodevelopmental disorder mutation locks G proteins in the transitory pre-activated state

Nature Communications(2024)10.1038/s41467-024-50964-z

N/A

0DataRank · unranked

17 citations

B. Krumm, Nicholas J. Kapolka, W.H. Ludlam, Meng Cui, Sepehr Mani +15 more

Advances in yeast synthetic biology for human G protein–coupled receptor biology and pharmacology

Current Opinion in Biotechnology(2024)10.1016/j.copbio.2024.103176

N/A

0DataRank · unranked

5 citations

Geoffrey J. Taghon, Daniel G. Isom, Nicholas J. Kapolka

A neurodevelopmental disorder mutation locks G proteins in the transitory pre-activated state

UNC Libraries(2025)10.17615/p1he-g624

N/A

0DataRank · unranked

0 citations

Tyler J. Lefevre, Ning Ma, Kevin M. Knight, Alan V. Smrcka, Sepehr Mani +15 more

Proton‐gated coincidence detection is a common feature of GPCR signaling

The FASEB Journal(2021)10.1096/fasebj.2021.35.s1.04123

N/A

0DataRank · unranked

0 citations

Jacob B. Rowe, Geoffrey J. Taghon, William M. Morgan, Corin R. O’Shea, Daniel G. Isom +1 more

The evolution and mechanism of GPCR proton sensing

Journal of Biological Chemistry(2020)10.1074/jbc.ra120.016352

N/A

0DataRank · unranked

74 citations

Nicholas J. Kapolka, Geoffrey J. Taghon, William M. Morgan, Daniel G. Isom, Jacob B. Rowe