Jonathan C. Kagan

Also affiliated with Harvard University, Boston Children's Museum

Immunology and MicrobiologyBiochemistry, Genetics and Molecular Biology

Pilot corpus only

This score is computed over theSindex pilot corpus and does not cover the full scientific literature. Scores are relative to papers we have ingested — papers, authors, and institutions outside the pilot are not represented. Methodology.

Top 100%percentile

0Author DataRank

Indexed papers

0in pilot corpus

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Papers

Driven by 40 papers. Top paper: “Gasdermin D permeabilization of mitochondrial inner and outer membranes accelerates and enhances pyroptosis”.

Gasdermin D permeabilization of mitochondrial inner and outer membranes accelerates and enhances pyroptosis

Immunity(2023)10.1016/j.immuni.2023.10.004

N/A

0.938DataRank · unranked

518 citations

Cong Jiang, Winston Chang, Haiwei Zhang, Jinsu An, Felicia Ho +22 more

Molecular mechanisms of gasdermin D pore-forming activity

Nature Immunology(2023)10.1038/s41590-023-01526-w

N/A

0.832DataRank · unranked

255 citations

Jonathan C. Kagan, Pascal Devant

Targeting innate immune pathways for cancer immunotherapy

Immunity(2023)10.1016/j.immuni.2023.07.018

N/A

0.805DataRank · unranked

213 citations

Jonathan C. Kagan, Longyue L. Cao

Inflammasomes within Hyperactive Murine Dendritic Cells Stimulate Long-Lived T Cell-Mediated Anti-tumor Immunity

Cell Reports(2020)10.1016/j.celrep.2020.108381

N/A

0.767DataRank · unranked

165 citations

Francesco Borriello, Ohn A. Chow, Benjamin A. Doran, Ira Fleming, Derek J. Theisen +6 more

Glycine inhibits NINJ1 membrane clustering to suppress plasma membrane rupture in cell death

eLife(2022)10.7554/elife.78609

N/A

0.723DataRank · unranked

123 citations

Ragnhild SR Sætra, Allen Volchuk, Marit Bugge, Pascal Devant, Bjørnar Sporsheim +7 more

Correction of age-associated defects in dendritic cells enables CD4+ T cells to eradicate tumors

Cell(2024)10.1016/j.cell.2024.05.026

N/A

0.670DataRank · unranked

86 citations

Stephanie N. Kennedy, J. Park, Francesco Boriello, Pascal Devant, Anh Cao +10 more

Emerging roles of peroxisomes in viral infections

Trends in Cell Biology(2021)10.1016/j.tcb.2021.09.010

N/A

0.612DataRank · unranked

58 citations

Mariana Marques, Bruno Ramos, Jonathan C. Kagan, Daniela Ribeiro, Ana Ferreira

Evolution-inspired redesign of the LPS receptor caspase-4 into an interleukin-1β–converting enzyme

Science Immunology(2021)10.1126/sciimmunol.abh3567

N/A

0.581DataRank · unranked

47 citations

Anh Cao, Jonathan C. Kagan, Pascal Devant

Structural transitions enable interleukin-18 maturation and signaling

Immunity(2024)10.1016/j.immuni.2024.04.015

N/A

0.542DataRank · unranked

36 citations

Jeffrey P. Bonin, Pascal Devant, Zhuoyi Liang, Alexander I. M. Sever, Julian Mintseris +7 more

ROS-dependent palmitoylation is an obligate licensing modification for GSDMD pore formation

bioRxiv (Cold Spring Harbor Laboratory)(2023)10.1101/2023.03.07.531538

N/A

0.538DataRank · unranked

35 citations

Liam B. Healy, Liron David, Caitlin Walker, Pietro Fontana, Ying Dong +8 more

Gasdermin Pore Forming Activities that Promote Inflammation from Living and Dead Cells

Journal of Molecular Biology(2021)10.1016/j.jmb.2021.167427

N/A

0.434DataRank · unranked

17 citations

Jonathan C. Kagan, Anh Cao

Three functionally distinct classes of cGAS proteins in nature revealed by self-DNA-induced interferon responses

bioRxiv (Cold Spring Harbor Laboratory)(2022)10.1101/2022.03.09.483681

N/A

0.241DataRank · unranked

4 citations

Wen Zhou, Apurva A. Govande, Dustin C. Hancks, Philip J. Kranzusch, Jonathan C. Kagan +1 more

Evolution-inspired dissection of caspase activities enables the redesign of caspase-4 into an LPS sensing interleukin-1 converting enzyme

bioRxiv (Cold Spring Harbor Laboratory)(2020)10.1101/2020.12.07.413732

N/A

0.165DataRank · unranked

2 citations

Anh Cao, Jonathan C. Kagan, Pascal Devant

Species-specific self-DNA detection mechanisms by mammalian cyclic GMP-AMP synthases

Science Immunology(2023)10.1126/sciimmunol.abp9765

N/A

0DataRank · unranked

18 citations

Stephanie N. Kennedy, Kristin M. Bahleda, Kailey M. Slavik, Wen Zhou, Apurva A. Govande +4 more

Inflammasomes as regulators of non-infectious disease

Seminars in Immunology(2023)10.1016/j.smim.2023.101815

N/A

0DataRank · unranked

12 citations

Jonathan C. Kagan, Daniel Okin

Innate immunity decreases pathogen diversity during infection

Proceedings of the National Academy of Sciences(2023)10.1073/pnas.2314237120

N/A

0DataRank · unranked

1 citations

Jonathan C. Kagan

Beyond natural biology: rewiring cellular networks to study innate immunity

Current Opinion in Immunology(2023)10.1016/j.coi.2023.102349

N/A

0DataRank · unranked

2 citations

Jonathan C. Kagan, Lauren M. Landau

Infection infidelities drive innate immunity

Science(2023)10.1126/science.ade9733

N/A

0DataRank · unranked

28 citations

Jonathan C. Kagan

ROS-dependent S-palmitoylation activates cleaved and intact gasdermin D

Nature(2024)10.1038/s41586-024-07373-5

N/A

0DataRank · unranked

243 citations

Liam B. Healy, Liron David, Caitlin Walker, Tarick J. El‐Baba, Corinne A. Lutomski +18 more

The palmitoylation of gasdermin D directs its membrane translocation and pore formation during pyroptosis

Science Immunology(2024)10.1126/sciimmunol.adn1452

N/A

0DataRank · unranked

183 citations

Alan Y. Hsu, Laxman Ghimire, Muhammad Tahir, Pascal Devant, Pietro Fontana +19 more

Candida albicans extracellular vesicles trigger type I IFN signalling via cGAS and STING

Nature Microbiology(2024)10.1038/s41564-023-01546-0

N/A

0DataRank · unranked

73 citations

Geneva N. Kwaku, Christopher Reardon, Nida S. Khan, Daniel Zamith‐Miranda, Robert Żarnowski +19 more

Pyroptotic cell corpses are crowned with F-actin-rich filopodia that engage CLEC9A signaling in incoming dendritic cells

Nature Immunology(2024)10.1038/s41590-024-02024-3

N/A

0DataRank · unranked

31 citations

Mercedes Monteleone, Daniel Fisch, A Libert, Robert J. Ju, Joon H. Choi +16 more

Strategies of bacterial detection by inflammasomes

Cell chemical biology(2024)10.1016/j.chembiol.2024.03.009

N/A

0DataRank · unranked

10 citations

Jonathan C. Kagan, Jordan B. Jastrab

A pan-family screen of nuclear receptors in immunocytes reveals ligand-dependent inflammasome control

Immunity(2024)10.1016/j.immuni.2024.10.010

N/A

0DataRank · unranked

9 citations

Yanbo Zhang, Kyungsub Kim, Jichang Han, Daniel Okin, Zhaozhao Jiang +11 more

pLxIS-containing domains are biochemically flexible regulators of interferons and metabolism

Molecular Cell(2024)10.1016/j.molcel.2024.05.030

N/A

0DataRank · unranked

8 citations

Neha Chaudhary, Yun Chen Tien, Magdalena Rogozinska, Shakchhi Joshi, Cong-Hui Yao +7 more

Waking the sleeping giant: Single-stranded DNA binds Schlafen 11 to initiate innate immune responses

Science Immunology(2024)10.1126/sciimmunol.adp4474

N/A

0DataRank · unranked

3 citations

Jonathan C. Kagan, Stephanie A. Ragland

LPS binding caspase activation and recruitment domains (CARDs) are bipartite lipid binding modules

bioRxiv (Cold Spring Harbor Laboratory)(2024)10.1101/2024.10.07.617105

N/A

0DataRank · unranked

0 citations

Pascal Devant, Chengliang Wang, Mengyu Sun, Stephanie N. Kennedy, Jianbin Ruan +2 more

ARIES domains: functional signaling units of type I interferon responses

FEBS Journal(2025)10.1111/febs.70023

N/A

0DataRank · unranked

3 citations

Jonathan C. Kagan, Lauren M. Landau

HDAC6 mediates an aggresome-like mechanism for NLRP3 and pyrin inflammasome activation

Science(2020)10.1126/science.aas8995

N/A

0DataRank · unranked

387 citations

Roberto Negro, Yuzi Tian, Arthur V. Hauenstein, Giuseppe Di Caprio, Wesley Skillern +14 more

Downstream of gasdermin D cleavage, a Ragulator-Rag-mTORC1 pathway promotes pore formation and pyroptosis

bioRxiv (Cold Spring Harbor Laboratory)(2020)10.1101/2020.11.02.362517

N/A

0DataRank · unranked

6 citations

Iva Hafner‐Bratkovič, Jonathan C. Kagan, Charles L. Evavold

Virus-mediated inactivation of anti-apoptotic Bcl-2 family members promotes Gasdermin-E-dependent pyroptosis in barrier epithelial cells

Immunity(2021)10.1016/j.immuni.2021.04.012

N/A

0DataRank · unranked

136 citations

Aleksandra Prochera, Laurellee Payne, Avi Smith, Jonathan A. Garlick, Jonathan C. Kagan +1 more

Innate immune detection of lipid oxidation as a threat assessment strategy

Nature reviews. Immunology(2021)10.1038/s41577-021-00618-8

N/A

0DataRank · unranked

121 citations

Jonathan C. Kagan, Dania Zhivaki

NLRP3 inflammasomes that induce antitumor immunity

Trends in Immunology(2021)10.1016/j.it.2021.05.001

N/A

0DataRank · unranked

59 citations

Jonathan C. Kagan, Dania Zhivaki

Deep-sea microbes as tools to refine the rules of innate immune pattern recognition

Science Immunology(2021)10.1126/sciimmunol.abe0531

N/A

0DataRank · unranked

39 citations

Courtney E. Chandler, Valentina Poli, Francesca M. Gardner, Aranteiti Tekiau, Richard D. Smith +10 more

Control of innate immunity by the cGAS‐STING pathway

Immunology and Cell Biology(2022)10.1111/imcb.12555

N/A

0DataRank · unranked

41 citations

Jonathan C. Kagan, Kenta Mosallanejad

Diverse Control Mechanisms of the Interleukin-1 Cytokine Family

Frontiers in Cell and Developmental Biology(2022)10.3389/fcell.2022.910983

N/A

0DataRank · unranked

29 citations

Jonathan C. Kagan, Charles L. Evavold

Protocol to purify recombinant inflammatory caspases and assess their catalytic activity in vitro

STAR Protocols(2022)10.1016/j.xpro.2022.101848

N/A

0DataRank · unranked

4 citations

Jonathan C. Kagan, Pascal Devant

Phagosome-mediated activation of STING during diverse bacterial infections

bioRxiv (Cold Spring Harbor Laboratory)(2022)10.1101/2022.10.28.514268

N/A

0DataRank · unranked

4 citations

Jonathan C. Kagan, Stephanie A. Ragland

Gasdermin D pore-forming activity is redox-sensitive

Cell Reports(2023)10.1016/j.celrep.2023.112008

N/A

0DataRank · unranked

135 citations

Elvira Boršić, Elsy M. Ngwa, Haopeng Xiao, Edward T. Chouchani, Jay R. Thiagarajah +4 more

Structural insights into cytokine cleavage by inflammatory caspase-4

Nature(2023)10.1038/s41586-023-06751-9

N/A

0DataRank · unranked

83 citations

Ying Dong, Julian Mintseris, Weiyi Ma, Steven P. Gygi, Hao Wu +2 more