Christopher S. Chen

Also affiliated with Harvard University, University of California, Los Angeles, Harvard University Press, University of Saskatchewan, University of Massachusetts Boston, Boston University Academy, Inspire

Biochemistry, Genetics and Molecular BiologyEngineeringMedicine

Pilot corpus only

This score is computed over theSindex pilot corpus and does not cover the full scientific literature. Scores are relative to papers we have ingested — papers, authors, and institutions outside the pilot are not represented. Methodology.

Top 100%percentile

0Author DataRank

Indexed papers

2in pilot corpus

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Why this DataRank?

An author's DataRank is the sum of the DataRanks of all 2 indexed papers attributed to them. A prolific author with many moderate-impact papers can outrank one with a single high-impact paper.

Author scores recompute whenever paper DataRanks are refreshed, so this number lags the underlying paper scores by at most one batch run.

Read the full methodology →

Papers

Driven by 49 papers. Top paper: “Transient Support from Fibroblasts is Sufficient to Drive Functional Vascularization in Engineered Tissues”.

Transient Support from Fibroblasts is Sufficient to Drive Functional Vascularization in Engineered Tissues

Advanced Functional Materials(2020)10.1002/adfm.202003777

N/A

2.3DataRank · unranked

76 citations

Alex Lammers, Subramanian Sundaram, Logan Rubio, Amanda X. Chen, Linqing Li +4 more

Mechanotransduction – a field pulling together?

Journal of Cell Science(2008)10.1242/jcs.023507

N/A

0.939DataRank · unranked

523 citations

Christopher S. Chen

Myosin Sequestration Regulates Sarcomere Function, Cardiomyocyte Energetics, and Metabolism, Informing the Pathogenesis of Hypertrophic Cardiomyopathy

Circulation(2020)10.1161/circulationaha.119.042339

N/A

0.872DataRank · unranked

333 citations

Amanda C. Garfinkel, Gabriela Venturini, Hiroko Wakimoto, Giuliana G. Repetti, Lorenzo Álamo +23 more

Differential stiffness between brain vasculature and parenchyma promotes metastatic infiltration through vessel co-option

Nature Cell Biology(2024)10.1038/s41556-024-01532-6

N/A

0.720DataRank · unranked

28 citations

Amy E. Stoddard, Bryan P. Sutherland, Olivia Courbot, Roger Oria, Linqing Li +10 more

Parallelized multidimensional analytic framework applied to mammary epithelial cells uncovers regulatory principles in EMT

Nature Communications(2023)10.1038/s41467-023-36122-x

N/A

0.510DataRank · unranked

29 citations

Dante Bolzan, Ahmed Youssef, Keith A. Gagnon, Heather Hook, Gopal Karemore +17 more

Fast, multiplane line-scan confocal microscopy using axially distributed slits

Biomedical Optics Express(2021)10.1364/boe.417286

N/A

0.505DataRank · unranked

28 citations

Howard J. Gritton, Shoshana L. Das, Timothy D. Weber, Christopher S. Chen, Xue Han +2 more

Rapid tissue perfusion using sacrificial percolation of anisotropic networks

Matter(2024)10.1016/j.matt.2024.04.001

N/A

0.434DataRank · unranked

17 citations

Heng‐Hua Hsu, Subramanian Sundaram, Keith A. Gagnon, Sudong Kim, Joshua H. Lee +4 more

Regulation of sarcomere formation and function in the healthy heart requires a titin intronic enhancer

Journal of Clinical Investigation(2024)10.1172/jci183353

N/A

0.360DataRank · unranked

10 citations

Seong Won Kim, David Saul, Meraj Neyazi, Manuel Schmid, Hiroko Wakimoto +27 more

Distinct effects of different matrix proteoglycans on collagen fibrillogenesis and cell-mediated collagen reorganization

bioRxiv (Cold Spring Harbor Laboratory)(2020)10.1101/2020.08.30.274001

N/A

0.312DataRank · unranked

7 citations

Lucas Smith, Gauri Khandekar, Pavan Patel, Christopher Yu, Kehan Zhang +4 more

Suppression of NRAS-mutant melanoma growth with NRAS-targeting Antisense Oligonucleotide treatment reveals therapeutically relevant kinase co-dependencies

Communications Medicine(2025)10.1038/s43856-025-00932-5

N/A

0.208DataRank · unranked

3 citations

Yixuan James Zheng, Tiange Qu, Dasha Hohlova, Ciara Callanan, Li-Nan Chen +12 more

Analysis of the Deformation of the Nucleus as a Result of Alterations of the Cell Adhesion Area

Advances in Bioengineering(2003)10.1115/imece2003-42905

N/A

0.104DataRank · unranked

1 citations

Christopher S. Chen, Alexander A. Spector, Ronald P. Jean

Directing Cholangiocyte Morphogenesis in Natural Biomaterial Scaffolds

bioRxiv (Cold Spring Harbor Laboratory)(2021)10.1101/2021.04.09.439196

N/A

0DataRank · unranked

4 citations

Christopher S. Chen, Sangeeta N. Bhatia, Quinton Smith

A multi-organ chip with matured tissue niches linked by vascular flow

Nature Biomedical Engineering(2022)10.1038/s41551-022-00882-6

N/A

0DataRank · unranked

452 citations

Diogo Teles, Keith Yeager, Daniel Naveed Tavakol, Yimu Zhao, Alan Chramiec +21 more

The clinical landscape of cell-free DNA alterations in 1671 patients with advanced biliary tract cancer

Annals of Oncology(2022)10.1016/j.annonc.2022.09.150

N/A

0DataRank · unranked

143 citations

Francesco Facchinetti, Daniel DiToro, Islam Baiev, Umair Majeed, Sylvia A. Reyes +24 more

Engineered patterns of Notch ligands Jag1 and Dll4 elicit differential spatial control of endothelial sprouting

iScience(2022)10.1016/j.isci.2022.104306

N/A

0DataRank · unranked

23 citations

Tommaso Ristori, Oscar M. J. A. Stassen, Jaakko J. Ahlberg, Jonne J.J. de Bijl, Christopher S. Chen +4 more

The dichotomous function of FUNDC1‐dependent mitophagy in doxorubicin cardiotoxicity

The FASEB Journal(2022)10.1096/fasebj.2022.36.s1.r3726

N/A

0DataRank · unranked

0 citations

Qiangrong Liang, Satoru Kobayashi, Tony Nguyen, Christopher S. Chen

A 3D biomimetic model of lymphatics reveals cell–cell junction tightening and lymphedema via a cytokine-induced ROCK2/JAM-A complex

Proceedings of the National Academy of Sciences(2023)10.1073/pnas.2308941120

N/A

0DataRank · unranked

21 citations

Siu‐Lung Chan, Yang Lee, William J. Polacheck, Sukyoung Kwak, Aiyun Wen +10 more

Differential vascular endothelial cell toxicity of established and novel BCR-ABL tyrosine kinase inhibitors

PLoS ONE(2023)10.1371/journal.pone.0294438

N/A

0DataRank · unranked

17 citations

Richard J. Travers, Alanna Farrell, Qing Lu, Jennifer Bays, Alec Stepanian +3 more

Deconstructing the role of MALAT1 in MAPK-signaling in melanoma: insights from antisense oligonucleotide treatment

Oncotarget(2023)10.18632/oncotarget.28447

N/A

0DataRank · unranked

28 citations

Yixuan James Zheng, Wilson Ho, Li-Nan Chen, Ciara Callanan, Christopher S. Chen +5 more

Notch1 cortical signaling regulates epithelial architecture and cell–cell adhesion

The Journal of Cell Biology(2023)10.1083/jcb.202303013

N/A

0DataRank · unranked

14 citations

Kyle A. Jacobs, Tania Singh, Lakyn Mayo, Annie Lin, Christopher S. Chen +3 more

Fibroblast clearance of damaged tissue following laser ablation in engineered microtissues

APL Bioengineering(2023)10.1063/5.0133478

N/A

0DataRank · unranked

4 citations

Anish Vasan, Christopher S. Chen, Jeroen Eyckmans, Megan E. Griebel

Bmp9 regulates Notch signaling and the temporal dynamics of angiogenesis via Lunatic Fringe

bioRxiv (Cold Spring Harbor Laboratory)(2023)10.1101/2023.09.25.557123

N/A

0DataRank · unranked

8 citations

Raphaël Thuret, Erika Hooker, Peter Quicke, Kevin Lanthier, Kalonji Ntumba +7 more

Matrix architecture and mechanics regulate myofibril organization, costamere assembly, and contractility of engineered myocardial microtissues

bioRxiv (Cold Spring Harbor Laboratory)(2023)10.1101/2023.10.20.563346

N/A

0DataRank · unranked

5 citations

Javiera Jillberto, Austin E. Stis, Darcy D. Huang, Jason Lo, Christopher D. Davidson +9 more

The therapeutically actionable long non-coding RNA ‘T-RECS’ is essential to cancer cells’ survival in NRAS/MAPK-driven melanoma

Research Square(2023)10.21203/rs.3.rs-1297358/v3

N/A

0DataRank · unranked

1 citations

Li-Nan Chen, Yixuan James Zheng, Wilson Ho, Martina Sanlorenzo, Igor Vujic +21 more

The therapeutically actionable long non-coding RNA ‘T-RECS’ is essential to cell survival in NRAS/MAPK-driven melanoma

Research Square(2023)10.21203/rs.3.rs-1297358/v2

N/A

0DataRank · unranked

0 citations

Li-Nan Chen, Yixuan James Zheng, Wilson Ho, Martina Sanlorenzo, Igor Vujic +21 more

Sacrificial capillary pumps to engineer multiscalar biological forms

Nature(2024)10.1038/s41586-024-08175-5

N/A

0DataRank · unranked

53 citations

Josh Lee, Isabel M. Bjørge, Christos Michas, Sudong Kim, Alex Lammers +5 more

Induced pluripotent stem cell-derived cardiomyocyte in vitro models: benchmarking progress and ongoing challenges

Nature Methods(2024)10.1038/s41592-024-02480-7

N/A

0DataRank · unranked

36 citations

Samuel J. DePalma, Maggie E. Jewett, M. Çağatay Karakan, Yih-Mei Lin, Paria Mir Hashemian +16 more

A Protein‐Adsorbent Hydrogel with Tunable Stiffness for Tissue Culture Demonstrates Matrix‐Dependent Stiffness Responses

Advanced Functional Materials(2024)10.1002/adfm.202309567

N/A

0DataRank · unranked

24 citations

Megan E. Griebel, Marina Uroz, Saniya Yesmin Bubli, Keith A. Gagnon, Britta Trappmann +4 more

The therapeutically actionable long non-coding RNA ‘T-RECS’ is essential to cancer cells’ survival in NRAS/MAPK-driven melanoma

Molecular Cancer(2024)10.1186/s12943-024-01955-7

N/A

0DataRank · unranked

15 citations

Li-Nan Chen, Yixuan James Zheng, Wilson Ho, Martina Sanlorenzo, Igor Vujic +21 more

MicroBundleCompute: Automated segmentation, tracking, and analysis of subdomain deformation in cardiac microbundles

PLoS ONE(2024)10.1371/journal.pone.0298863

N/A

0DataRank · unranked

9 citations

Javiera Jilberto, M. Çağatay Karakan, Xining Gao, Samuel J. DePalma, Shoshana L. Das +7 more

Geometry and length control of 3D engineered heart tissues using direct laser writing

Lab on a Chip(2024)10.1039/d3lc00752a

N/A

0DataRank · unranked

5 citations

Jourdan K. Ewoldt, Addianette J. Segarra, Subramanian Sundaram, Miranda C. Wang, Alice E. White +3 more

Multicompartment duct platform to study epithelial–endothelial crosstalk associated with lung adenocarcinoma

APL Bioengineering(2024)10.1063/5.0207228

N/A

0DataRank · unranked

2 citations

Jessie Huang, Olivia T. Hix, Veronica Hui, Anne Hinds, Esther Bullitt +4 more

MicroBundlePillarTrack: A Python package for automated segmentation, tracking, and analysis of pillar deflection in cardiac microbundles

arXiv (Cornell University)(2024)10.48550/arxiv.2405.11096

N/A

0DataRank · unranked

0 citations

Xining Gao, Samuel J. DePalma, Jourdan K. Ewoldt, Miranda C. Wang, Shoshana L. Das +6 more

Perivascular cells function as key mediators of mechanical and structural changes in vascular capillaries

Science Advances(2025)10.1126/sciadv.adp3789

N/A

0DataRank · unranked

27 citations

Maria Elisa Quezado Lima Verde, Alice Corrêa Silva‐Sousa, Amin Mansoorifar, Avathamsa Athirasala, Ramesh Subbiah +14 more

Empagliflozin enhances metabolic efficiency and improves left ventricular hypertrophy in a hypertrophic cardiomyopathy mouse model

European Heart Journal(2025)10.1093/eurheartj/ehaf324

N/A

0DataRank · unranked

16 citations

Jarrod Moore, Fuzhong Qin, Salva R. Yurista, Aifeng Zhang, Huamei He +18 more

TapeTech microfluidic connectors: adhesive tape-enabled solution for organ-on-a-chip system integration

Lab on a Chip(2025)10.1039/d4lc00970c

N/A

0DataRank · unranked

7 citations

Abraham C.I. van Steen, Delaney Gray-Scherr, Jessica L. Teo, Anish Vasan, Joshua Jeon +7 more

A 3D in vitro model of the human hepatobiliary junction

bioRxiv (Cold Spring Harbor Laboratory)(2025)10.1101/2025.07.11.664464

N/A

0DataRank · unranked

1 citations

Katarzyna A. Grzelak, Katie Katsuyama, Vardhman Kumar, Bess M. Miller, Jong Won Yun +9 more

Three‐dimensional modeling of flow through microvascular beds and surrounding interstitial spaces

Bioengineering & Translational Medicine(2025)10.1002/btm2.70085

N/A

0DataRank · unranked

0 citations

Alanna Farrell, Emily J. Davis, Subramanian Sundaram, Abraham C.I. van Steen, Jessica L. Teo +3 more

Fluorescein-based SynNotch adaptors for regulating gene expression responses to diverse extracellular and matrix-based cues

Nature Communications(2025)10.1038/s41467-025-56148-7

N/A

0DataRank · unranked

5 citations

Christopher J. Kuffner, Alexander M. Marzilli, Ryan Emily Miller, Zachary E. Silfen, Jeffrey B. McMahan +4 more

Distinct effects of different matrix proteoglycans on collagen fibrillogenesis and cell-mediated collagen reorganization

Scientific Reports(2020)10.1038/s41598-020-76107-0

N/A

0DataRank · unranked

92 citations

Lucas Smith, Gauri Khandekar, Pavan Patel, Christopher Yu, Kehan Zhang +4 more

Uncovering mutation-specific morphogenic phenotypes and paracrine-mediated vessel dysfunction in a biomimetic vascularized mammary duct platform

Nature Communications(2020)10.1038/s41467-020-17102-x

N/A

0DataRank · unranked

58 citations

William J. Polacheck, Michaela Welch, Keith A. Gagnon, Thijs Koorman, Sudong Kim +4 more

Controlled Apoptosis of Stromal Cells to Engineer Human Microlivers

Advanced Functional Materials(2020)10.1002/adfm.201910442

N/A

0DataRank · unranked

17 citations

Arnav Chhabra, Hyun‐Ho Greco Song, Heather E. Fleming, Christopher S. Chen, Sangeeta N. Bhatia +1 more

Voltage Imaging of Cardiac Cells and Tissue Using the Genetically Encoded Voltage Sensor Archon1

iScience(2020)10.1016/j.isci.2020.100974

N/A

0DataRank · unranked

16 citations

Shoshana L. Das, Hua-An Tseng, Jad Noueihed, Fernando R. Fernandez, John A. White +3 more

Optogenetic currents in myofibroblasts acutely alter electrophysiology and conduction of co-cultured cardiomyocytes

bioRxiv (Cold Spring Harbor Laboratory)(2020)10.1101/2020.06.02.124529

N/A

0DataRank · unranked

2 citations

Yu Shi, Christopher S. Chen, Daniel H. Reich, Emilia Entcheva, Leslie Tung +1 more

Harnessing Mechanobiology for Tissue Engineering

Developmental Cell(2021)10.1016/j.devcel.2020.12.017

N/A

0DataRank · unranked

134 citations

Marina Uroz, Jennifer Bays, Christopher S. Chen, Sudong Kim

Force-FAK signaling coupling at individual focal adhesions coordinates mechanosensing and microtissue repair

Nature Communications(2021)10.1038/s41467-021-22602-5

N/A

0DataRank · unranked

89 citations

Marc Fernández, Elijah N. Holland, Andrés F. García, Nicolas Castro, Eric B. O’Neill +6 more

SARS-CoV-2 Disrupts Proximal Elements in the JAK-STAT Pathway

Journal of Virology(2021)10.1128/jvi.00862-21

N/A

0DataRank · unranked

85 citations

Nazimuddin Khan, Brianna J. Close, Raghuveera Kumar Goel, Benjamin C. Blum, Alexander H. Tavares +14 more

Optogenetic current in myofibroblasts acutely alters electrophysiology and conduction of co-cultured cardiomyocytes

Scientific Reports(2021)10.1038/s41598-021-83398-4

N/A

0DataRank · unranked

23 citations

Yu Shi, Christopher S. Chen, Daniel H. Reich, Emilia Entcheva, Leslie Tung +1 more

Directing Cholangiocyte Morphogenesis in Natural Biomaterial Scaffolds

Advanced Science(2021)10.1002/advs.202102698

N/A

0DataRank · unranked

10 citations

Jennifer Bays, Linqing Li, Haniyah Shareef, Christopher S. Chen, Sangeeta N. Bhatia +1 more