Karen A. Kirby

Also affiliated with Children's Healthcare of Atlanta

MedicineImmunology and MicrobiologyBiochemistry, Genetics and Molecular Biology

Pilot corpus only

This score is computed over theSindex pilot corpus and does not cover the full scientific literature. Scores are relative to papers we have ingested — papers, authors, and institutions outside the pilot are not represented. Methodology.

Top 100%percentile

0Author DataRank

Indexed papers

0in pilot corpus

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Papers

Driven by 25 papers. Top paper: “Rotten to the core: antivirals targeting the HIV-1 capsid core”.

Rotten to the core: antivirals targeting the HIV-1 capsid core

Retrovirology(2021)10.1186/s12977-021-00583-z

N/A

0.637DataRank · unranked

69 citations

Alexa A. Snyder, Karen A. Kirby, Philip R. Tedbury, Monika Raj, Zhengqiang Wang +2 more

Novel HIV-1 capsid-targeting small molecules of the PF74 binding site

European Journal of Medicinal Chemistry(2020)10.1016/j.ejmech.2020.112626

N/A

0.505DataRank · unranked

28 citations

Mary C. Casey, Sanjeev Kumar V. Vernekar, Rajkumar Lalji Sahani, Jayakanth Kankanala, Karen A. Kirby +8 more

Chemical profiling of HIV-1 capsid-targeting antiviral PF74

European Journal of Medicinal Chemistry(2020)10.1016/j.ejmech.2020.112427

N/A

0.494DataRank · unranked

26 citations

Mary C. Casey, Sanjeev Kumar V. Vernekar, Ha T., Rajkumar Lalji Sahani, Karen A. Kirby +8 more

Molecular Dynamics Free Energy Simulations Reveal the Mechanism for the Antiviral Resistance of the M66I HIV-1 Capsid Mutation

Viruses(2021)10.3390/v13050920

N/A

0.442DataRank · unranked

18 citations

Ronald M. Levy, Karen A. Kirby, Zhengqiang Wang, Stefan G. Sarafianos, Nanjie Deng +1 more

Discovery of New Small Molecule Hits as Hepatitis B Virus Capsid Assembly Modulators: Structure and Pharmacophore-Based Approaches

Viruses(2021)10.3390/v13050770

N/A

0.442DataRank · unranked

18 citations

Haijuan Du, Huanchun Zhang, Karen A. Kirby, Philip R. Tedbury, Jiashu Xie +3 more

Strategy to overcome a nirmatrelvir resistance mechanism in the SARS-CoV-2 nsp5 protease

Science Advances(2025)10.1126/sciadv.adv8875

N/A

0.385DataRank · unranked

12 citations

Shuiyun Lan, Ryan L. Slack, Zachary C. Lorson, Andres Emanuelli Castaner, Rachel Lee +13 more

Identification of clickable HIV-1 capsid-targeting probes for viral replication inhibition

Cell chemical biology(2024)10.1016/j.chembiol.2024.02.012

N/A

0.385DataRank · unranked

12 citations

Mary C. Casey, Grant A. L. Bare, Karen A. Kirby, Xin Wen, Gencheng Li +13 more

Subgenomic SARS-CoV-2 replicon and reporter replicon cell lines enable ultrahigh throughput antiviral screening and mechanistic studies with antivirals, viral mutations or host factors that affect COVID-19 replication

bioRxiv (Cold Spring Harbor Laboratory)(2021)10.1101/2021.12.29.474471

N/A

0.345DataRank · unranked

9 citations

Philip R. Tedbury, Yee Tsuey Ong, Raven Shah, Ryan L. Slack, Maria E. Cilento +10 more

Potency and metabolic stability: a molecular hybrid case in the design of novel PF74-like small molecules targeting HIV-1 capsid protein

RSC Medicinal Chemistry(2021)10.1039/d1md00292a

N/A

0.241DataRank · unranked

4 citations

Thamina Akther, Maria E. Cilento, Andres Emanuelli Castaner, Huanchun Zhang, Karen A. Kirby +4 more

Design and Synthesis of New GS-6207 Subtypes for Targeting HIV-1 Capsid Protein

International Journal of Molecular Sciences(2024)10.3390/ijms25073734

N/A

0DataRank · unranked

9 citations

William M. McFadden, Huanchun Zhang, Karen A. Kirby, Stefan G. Sarafianos, Zhengqiang Wang +1 more

Quinazolinone-based subchemotypes for targeting HIV-1 capsid protein: design and synthesis

Medicinal Chemistry Research(2024)10.1007/s00044-024-03305-0

N/A

0DataRank · unranked

2 citations

William M. McFadden, Huanchun Zhang, Karen A. Kirby, Philip R. Tedbury, Zhengqiang Wang +1 more

Disruption of LEDGF/p75-directed integration derepresses antisense transcription of the HIV-1 genome

bioRxiv (Cold Spring Harbor Laboratory)(2024)10.1101/2024.12.06.627169

N/A

0DataRank · unranked

3 citations

Darius Mahboubi, Maritza Puray‐Chavez, Raven Shah, Obiaara B. Ukah, Claudia C. Wahoski +14 more

Adapting a trapped ion mobility spectrometry-Q-TOF mass spectrometer for native mass spectrometry

ChemRxiv(2024)10.26434/chemrxiv-2024-xmjml-v3

N/A

0DataRank · unranked

0 citations

Benjamin Jones, Mark E. Ridgeway, Erin Panczyk, Árpád Somogyi, Desmond A. Kaplan +8 more

Adapting a Trapped Ion Mobility Spectrometry-Q-TOF for High m/z Native Mass Spectrometry and Surface-Induced Dissociation

Analytical Chemistry(2025)10.1021/acs.analchem.4c03557

N/A

0DataRank · unranked

10 citations

Benjamin J. Jones, Mark E. Ridgeway, Erin Panczyk, Árpád Somogyi, Desmond A. Kaplan +8 more

Considerations for capsid-targeting antiretrovirals in pre-exposure prophylaxis

Trends in Molecular Medicine(2025)10.1016/j.molmed.2025.01.013

N/A

0DataRank · unranked

5 citations

Mia Færch, Karen A. Kirby, Robert A. Dick, Bruce E. Torbett, Stefan G. Sarafianos +1 more

Structural, biophysical, and virological mechanistic characterization of HIV-1 capsid-targeting antivirals

bioRxiv (Cold Spring Harbor Laboratory)(2025)10.64898/2025.12.30.696960

N/A

0DataRank · unranked

1 citations

William M. McFadden, Lin Wang, Haijuan Du, Huanchun Zhang, Andres Emanuelli Castaner +16 more

Translocation of HIV capsid core through the Nuclear Pore Complex by affinity gradient

bioRxiv (Cold Spring Harbor Laboratory)(2025)10.1101/2025.10.02.680059

N/A

0DataRank · unranked

0 citations

Ryan L. Slack, Zachary C. Lorson, Andres Emanuelli Castaner, Krisztina Ambrus, Jonathan S. Winkjer +4 more

Proteins and Disease | Structural Basis of HIV Reverse Transcription, Inhibition, and Drug Resistance

Elsevier eBooks(2020)10.1016/b978-0-12-809633-8.21570-7

N/A

0DataRank · unranked

1 citations

Karen A. Kirby, Philip R. Tedbury, Stefan G. Sarafianos, Maria E. Cilento

Baicalein and Baicalin Inhibit SARS-CoV-2 RNA-Dependent-RNA Polymerase

Microorganisms(2021)10.3390/microorganisms9050893

N/A

0DataRank · unranked

136 citations

Katie Musall, Adrian Oo, Dongdong Cao, Bo Liang, Pouya Hassandarvish +10 more

Specific mutations in the HIV-1 G-tract of the 3′-polypurine tract cause resistance to integrase strand transfer inhibitors

Journal of Antimicrobial Chemotherapy(2021)10.1093/jac/dkab448

N/A

0DataRank · unranked

14 citations

Mai Kubota, Urara Shigemi, Hirotaka Ode, Yoshiyuki Yokomaku, Karen A. Kirby +3 more

Design, Synthesis and Characterization of HIV-1 CA-Targeting Small Molecules: Conformational Restriction of PF74

Viruses(2021)10.3390/v13030479

N/A

0DataRank · unranked

16 citations

Raquel Diana‐Rivero, Sanjeev Kumar V. Vernekar, Lei Wang, Haijuan Du, Huanchun Zhang +8 more

TRIM5α Restriction of HIV-1-N74D Viruses in Lymphocytes Is Caused by a Loss of Cyclophilin A Protection

Viruses(2022)10.3390/v14020363

N/A

0DataRank · unranked

16 citations

Lacy M. Simons, Karen A. Kirby, Ángel Bulnes‐Ramos, Pan Hu, Stefan G. Sarafianos +3 more

Structure-based virtual screening workflow to identify antivirals targeting HIV-1 capsid

Journal of Computer-Aided Molecular Design(2022)10.1007/s10822-022-00446-5

N/A

0DataRank · unranked

8 citations

Avik Biswas, R. S. K. Vijayan, Pierrick Craveur, Stefano Forli, Arthur J. Olson +6 more

Multidisciplinary studies with mutated HIV-1 capsid proteins reveal structural mechanisms of lattice stabilization

Nature Communications(2023)10.1038/s41467-023-41197-7

N/A

0DataRank · unranked

20 citations

Karen A. Kirby, William M. McFadden, Haijuan Du, Dandan Liu, Chaoyi Xu +10 more

TSAR, “Thermal Shift Analysis in R”, identifies endogenous molecules that interact with HIV-1 capsid hexamers

bioRxiv (Cold Spring Harbor Laboratory)(2023)10.1101/2023.11.29.569293

N/A

0DataRank · unranked

1 citations

Xinlin Gao, Zhijiang Ye, Xin Wen, Zachary C. Lorson, Hua Zheng +5 more