Robert A. Nicholas

University of North Carolina at Chapel Hill

Biochemistry, Genetics and Molecular BiologyImmunology and Microbiology

Pilot corpus only

This score is computed over theSindex pilot corpus and does not cover the full scientific literature. Scores are relative to papers we have ingested — papers, authors, and institutions outside the pilot are not represented. Methodology.

Top 6%percentile

0.173Author DataRank

Indexed papers

1in pilot corpus

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Why this DataRank?

An author's DataRank is the sum of the DataRanks of all 1 indexed paper attributed to them. A prolific author with many moderate-impact papers can outrank one with a single high-impact paper.

Author scores recompute whenever paper DataRanks are refreshed, so this number lags the underlying paper scores by at most one batch run.

Read the full methodology →

The highest-impact dataset this researcher has shared, ranked by DataRank — the single contribution doing the most to lift their data-sharing standing.

Draft Genome Sequences of Three Penicillin-Resistant Neisseria gonorrhoeae Strains Isolated in Cincinnati, Ohio, in 1994

Microbiology Resource Announcements(2021)10.1128/mra.00074-21

Top 67%

0.173DataRank

Top 67%2 citations

Tatum D. Mortimer, Robert A. Nicholas, Crista B. Wadsworth, Thomas C. Murphy

Papers

Driven by 41 papers — median percentile 33. Top paper: “High-Level Cefixime- and Ceftriaxone-Resistant Neisseria gonorrhoeae in France: Novel penA Mosaic Allele in a Successful International Clone Causes Treatment Failure”.

High-Level Cefixime- and Ceftriaxone-Resistant Neisseria gonorrhoeae in France: Novel penA Mosaic Allele in a Successful International Clone Causes Treatment Failure

UNC Libraries(2020)10.17615/xa1q-pe86

N/A

0.970DataRank · unranked

28 citations

Patrice Sednaoui, Anne Gallay, Makoto Ohnishi, Robert A. Nicholas, Daniel Golparian +1 more

Preclinical safety and efficacy characterization of an LpxC inhibitor against Gram-negative pathogens

Science Translational Medicine(2023)10.1126/scitranslmed.adf5668

N/A

0.561DataRank · unranked

41 citations

C. Skyler Cochrane, Javaria Najeeb, David M. Gooden, Carly A. Sciandra, Ping Fan +13 more

Draft Genome Sequences of Three Penicillin-Resistant Neisseria gonorrhoeae Strains Isolated in Cincinnati, Ohio, in 1994

Microbiology Resource Announcements(2021)10.1128/mra.00074-21

Top 67%

0.173DataRank

Top 67%2 citations

Tatum D. Mortimer, Robert A. Nicholas, Crista B. Wadsworth, Thomas C. Murphy

The Role of Amino Acids in Extracellular Loops of the Human P2Y 1 Receptor in Surface Expression and Activation Processes

UNC Libraries(2020)10.17615/trtx-es56

N/A

0.104DataRank · unranked

1 citations

Stefano Moro, T. Kendall Harden, Robert A. Nicholas, Kenneth A. Jacobson, Carsten Hoffmann

[ 32 P]2-iodo- N 6 -methyl-( N )-methanocarba-2′-deoxyadenosine-3′,5′-bisphosphate ([ 32 P]MRS2500), a novel radioligand for quantification of native P2Y 1 receptors

UNC Libraries(2020)10.17615/44e8-xn58

N/A

0DataRank · unranked

1 citations

Dayle Houston, T. Kendall Harden, M. Ohno, Kenneth A. Jacobson, Robert A. Nicholas

Diffusion of Antibiotics through the PilQ Secretin in Neisseria gonorrhoeae Occurs through the Immature, Sodium Dodecyl Sulfate-Labile Form

UNC Libraries(2020)10.17615/cp6a-2614

N/A

0DataRank · unranked

0 citations

Robert A. Nicholas

Localization of a putative second membrane association site in penicillin-binding protein 1B of Escherichia coli

UNC Libraries(2020)10.17615/g4m5-db81

N/A

0DataRank · unranked

0 citations

Derk E. SCHULTZ, Robert A. Nicholas, Chia-Chang WANG

Ser352 and Ser354 in the carboxyl terminus of the human P2Y1 receptor are required for agonist-promoted phosphorylation and internalization in MDCK cells: Phosphorylation and internalization of P2Y1 receptors

UNC Libraries(2020)10.17615/r2qs-6t42

N/A

0DataRank · unranked

0 citations

Robert A. Nicholas, T. Kendall Harden, Dayle Houston‐Cohen, Ai Dong Qi, Isabella Naruszewicz

Neisseria gonorrhoeae Penicillin-Binding Protein 3 Demonstrates a Pronounced Preference for N ε -Acylated Substrates

UNC Libraries(2020)10.17615/2aav-6c43

N/A

0DataRank · unranked

0 citations

William G. Gutheil, Sridhar Peddi, Robert A. Nicholas

Unusual Conformation of the SxN Motif in the Crystal Structure of Penicillin-Binding Protein A from Mycobacterium tuberculosis

Carolina Digital Repository (University of North Carolina at Chapel Hill)(2020)10.17615/rtmc-wj48

N/A

0DataRank · unranked

0 citations

Christopher Davies, Robert A. Nicholas, Alena Fedarovich

Crystal Structures of Penicillin-binding Protein 2 from Penicillin-susceptible and -resistant Strains of Neisseria gonorrhoeae Reveal an Unexpectedly Subtle Mechanism for Antibiotic Resistance

UNC Libraries(2020)10.17615/vwtk-hp70

N/A

0DataRank · unranked

0 citations

Robert A. Nicholas, Ashley M. Deacon, A.J. Powell, Joshua Tomberg, Christopher Davies

Control of gdhR Expression in Neisseria gonorrhoeae via Autoregulation and a Master Repressor (MtrR) of a Drug Efflux Pump Operon

UNC Libraries(2020)10.17615/xzxn-yp73

N/A

0DataRank · unranked

0 citations

William M. Shafer, Vijaya Dhulipala, Raúl G. Doyle, Afrin A. Begum, Ann E. Jerse +5 more

A Highly Conserved Interaction Involving the Middle Residue of the SXN Active-Site Motif Is Crucial for Function of Class B Penicillin-Binding Proteins: Mutational and Computational Analysis of PBP 2 from N. gonorrhoeae

Figshare(2020)10.17615/q249-7711

N/A

0DataRank · unranked

0 citations

Robert A. Nicholas, Joshua Tomberg, Christopher J. Davies, Brenda Temple, Alena Fedarovich

High-Throughput Screening for Novel Inhibitors of Neisseria gonorrhoeae Penicillin-Binding Protein 2

UNC Libraries(2020)10.17615/2dwp-ms97

N/A

0DataRank · unranked

0 citations

Yuri K. Peterson, Alena Fedarovich, Kevin A. Djordjevic, Christopher Davies, Shauna M. Swanson +1 more

Crystal Structures of Covalent Complexes of β-Lactam Antibiotics with Escherichia coli Penicillin-Binding Protein 5: Toward an Understanding of Antibiotic Specificity

UNC Libraries(2020)10.17615/sdkg-p119

N/A

0DataRank · unranked

0 citations

George Nicola, Christopher Davies, Robert A. Nicholas, R. F. Pratt, Joshua Tomberg

Structural Effect of the Asp345a Insertion in Penicillin-Binding Protein 2 from Penicillin-Resistant Strains of Neisseria gonorrhoeae

UNC Libraries(2020)10.17615/eqq1-zd64

N/A

0DataRank · unranked

0 citations

Alena Fedarovich, Christopher Davies, Joshua Tomberg, Edward Cook, Robert A. Nicholas

Physiological Regulation of ATP Release at the Apical Surface of Human Airway Epithelia

UNC Libraries(2020)10.17615/7bbd-n197

N/A

0DataRank · unranked

0 citations

Robert A. Nicholas, Richard C. Boucher, Silvia M. Kreda, Eduardo R. Lazarowski, Seiko F. Okada

Emergence of multidrug-resistant, extensively drug-resistant and untreatable gonorrhea

UNC Libraries(2020)10.17615/nj27-3p72

N/A

0DataRank · unranked

0 citations

Magnus Unemo, Robert A. Nicholas

Agonist Versus Antagonist Action of ATP at the P2Y 4 Receptor Is Determined by the Second Extracellular Loop

UNC Libraries(2020)10.17615/3a4v-zn14

N/A

0DataRank · unranked

0 citations

Ai Dong Qi, Robert A. Nicholas, Christopher L. Herold, T. Kendall Harden

The Role of the β5–α11 Loop in the Active-Site Dynamics of Acylated Penicillin-Binding Protein A from Mycobacterium tuberculosis

UNC Libraries(2020)10.17615/9kae-xt70

N/A

0DataRank · unranked

0 citations

Robert A. Nicholas, Christopher Davies, Alena Fedarovich

Species-Specific and Inhibitor-Dependent Conformations of LpxC: Implications for Antibiotic Design

UNC Libraries(2020)10.17615/kcyx-4n60

N/A

0DataRank · unranked

0 citations

Xiaofei Liang, Yaoxian Li, Adam W. Barb, Eric J. Toone, Shauna M. Swanson +8 more

Interaction energies between β-lactam antibiotics and E. coli penicillin-binding protein 5 by reversible thermal denaturation

UNC Libraries(2020)10.17615/rnc7-y766

N/A

0DataRank · unranked

0 citations

Brian K. Shoichet, Robert A. Nicholas, Beth M. Beadle

Mutations in PBP2 from ceftriaxone-resistant Neisseria gonorrhoeae alter the dynamics of the β3–β4 loop to favor a low-affinity drug-binding state

Journal of Biological Chemistry(2021)10.1016/j.jbc.2021.101188

N/A

0DataRank · unranked

23 citations

Joshua Tomberg, Carly A. Sciandra, Robert A. Nicholas, Christopher Davies, Pei Zhou +1 more

The Apical Targeting Signal of the P2Y 2 Receptor Is Located in Its First Extracellular Loop

UNC Libraries(2021)10.17615/3mm7-6969

N/A

0DataRank · unranked

0 citations

Ai Dong Qi, Robert A. Nicholas, Samuel C. Wolff

Crystal Structure of Wild-type Penicillin-binding Protein 5 from Escherichia coli: IMPLICATIONS FOR DEACYLATION OF THE ACYL-ENZYME COMPLEX

UNC Libraries(2021)10.17615/74d8-7e21

N/A

0DataRank · unranked

2 citations

George Nicola, Sandra Krings, Joshua Tomberg, Robert A. Nicholas, Christopher Davies

Random Mutagenesis of the Sheep Na,K-ATPase α1 Subunit Generating the Ouabain-resistant Mutant L793P

UNC Libraries(2021)10.17615/8yrt-0k28

N/A

0DataRank · unranked

0 citations

E. L. Burns, Elmer M. Price, Robert A. Nicholas

High yield expression of the Neurospora crassa plasma membrane H (+)-ATPase in Saccharomyces cerevisiae.

UNC Libraries(2021)10.17615/byar-rx93

N/A

0DataRank · unranked

0 citations

Gene Scarborough, U Rao, Robert A. Nicholas, Sanjoy K. Mahanty

Endoplasmic Reticulum/Golgi Nucleotide Sugar Transporters Contribute to the Cellular Release of UDP-sugar Signaling Molecules

UNC Libraries(2021)10.17615/2waj-5145

N/A

0DataRank · unranked

0 citations

Robert A. Nicholas, Shoko Nishihara, Eduardo R. Lazarowski, Wanda K. O’Neal, Charles R. Esther +3 more

The penC mutation conferring antibiotic resistance in Neisseria gonorrhoeae arises from a mutation in the PilQ secretin that interferes with multimer stability: GonococcalpilQmutants with increased antibiotic resistance

UNC Libraries(2021)10.17615/gt40-4k83

N/A

0DataRank · unranked

0 citations

Mei Hu, Shuqing Zhao, H Steven Seifert, Deborah M. Tobiason, Robert A. Nicholas

Charged residues in the C-terminus of the P2Y1 receptor constitute a basolateral-sorting signal

UNC Libraries(2021)10.17615/bx3a-7034

N/A

0DataRank · unranked

0 citations

Robert A. Nicholas, Ai Dong Qi, T. Kendall Harden, Samuel C. Wolff

Developing evidence-based resources for evaluating postgraduate trainees in the biomedical sciences

PLoS ONE(2022)10.1371/journal.pone.0278297

N/A

0DataRank · unranked

3 citations

Rebekah L. Layton, Paul B. Watkins, Robert A. Nicholas, Kim L. R. Brouwer, Jacqueline E. McLaughlin

Loss of P2Y1 receptor desensitization does not impact hemostasis or thrombosis despite increased platelet reactivity in vitro

Journal of Thrombosis and Haemostasis(2023)10.1016/j.jtha.2023.03.013

N/A

0DataRank · unranked

9 citations

Tasha N. Blatt, Tomohiro Kawano, Emily G. Clark, Nigel Mackman, Sebastian Murcia +6 more

Development and Validation of Multiplex Assays for Mouse and Human IgG and IgA to Neisseria gonorrhoeae Antigens

The Journal of Infectious Diseases(2024)10.1093/infdis/jiae153

N/A

0DataRank · unranked

4 citations

Marguerite B. Little, Kristie L. Connolly, Lixin Li, Robert A. Nicholas, Aleksandra E. Sikora +5 more

Ureidopenicillins Are Potent Inhibitors of Penicillin-Binding Protein 2 from Multidrug-Resistant Neisseria gonorrhoeae H041

ACS Infectious Diseases(2024)10.1021/acsinfecdis.3c00713

N/A

0DataRank · unranked

6 citations

Caleb M. Stratton, Sandeepchowdary Bala, María X. Cardenas-Alvarez, Robert A. Nicholas, Christopher Davies +1 more

Coordinated Transcriptional Increases in Cell Wall Synthesis Genes in Neisseria gonorrhoeae Lacking the Lytic Transglycosylase, ltgA

Current Microbiology(2025)10.1007/s00284-025-04261-7

N/A

0DataRank · unranked

1 citations

Alaa I. Telchy, Antonio T. Baines, Joseph P. Dillard, Robert A. Nicholas, Daniel Williams +1 more

Development and Validation of Multiplex Assays for Mouse and Human IgG and IgA to Neisseria gonorrhoeae Antigens

UNC Libraries(2025)10.17615/mk5c-0c09

N/A

0DataRank · unranked

0 citations

Erica L. Stover, Lixin Li, Robert A. Nicholas, Marcia M. Hobbs, Joseph A. Duncan +5 more

Mutations in penicillin-binding protein 2 from cephalosporin-resistant Neisseria gonorrhoeae hinder ceftriaxone acylation by restricting protein dynamics

Journal of Biological Chemistry(2020)10.1074/jbc.ra120.012617

N/A

0DataRank · unranked

37 citations

Jonathan M. Turner, Joshua Tomberg, Alena Fedarovich, Magnus Unemo, Robert A. Nicholas +2 more

Loss of P2Y1 receptor desensitization does not impact hemostasis or thrombosis despite increased platelet reactivity in vitro

UNC Libraries(2025)10.17615/g5hd-0m20

N/A

0DataRank · unranked

0 citations

Sebastian Murcia, Tomohiro Kawano, David S. Paul, Wolfgang Bergmeier, Nigel Mackman +7 more

Molecular and Structural Analysis of Mosaic Variants of Penicillin-Binding Protein 2 Conferring Decreased Susceptibility to Expanded-Spectrum Cephalosporins in Neisseria gonorrhoeae : Role of Epistatic Mutations

UNC Libraries(2020)10.17615/92jb-wx23

N/A

0DataRank · unranked

5 citations

Christopher Davies, Joshua Tomberg, Magnus Unemo, Robert A. Nicholas

Identification of Amino Acids Conferring High-Level Resistance to Expanded-Spectrum Cephalosporins in the penA Gene from Neisseria gonorrhoeae Strain H041

UNC Libraries(2020)10.17615/5xcv-6e15

N/A

0DataRank · unranked

3 citations

Robert A. Nicholas, Makoto Ohnishi, Joshua Tomberg, Magnus Unemo, Christopher Davies

Alanine 501 Mutations in Penicillin-Binding Protein 2 from Neisseria gonorrhoeae : Structure, Mechanism, and Effects on Cephalosporin Resistance and Biological Fitness

UNC Libraries(2020)10.17615/szae-9y15

N/A

0DataRank · unranked

3 citations

Joshua Tomberg, Leah R. Vincent, Alena Fedarovich, Robert A. Nicholas, Magnus Unemo +2 more

Robert A. Nicholas

Indexed papers

Top data-sharing exemplar

Papers