Robert M. Brosh

Computer ScienceBiochemistry, Genetics and Molecular Biology

Pilot corpus only

This score is computed over theSindex pilot corpus and does not cover the full scientific literature. Scores are relative to papers we have ingested — papers, authors, and institutions outside the pilot are not represented. Methodology.

Top 100%percentile

0Author DataRank

Indexed papers

1in pilot corpus

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Why this DataRank?

An author's DataRank is the sum of the DataRanks of all 1 indexed paper attributed to them. A prolific author with many moderate-impact papers can outrank one with a single high-impact paper.

Author scores recompute whenever paper DataRanks are refreshed, so this number lags the underlying paper scores by at most one batch run.

Read the full methodology →

Papers

Driven by 32 papers. Top paper: “Synthetic Lethal Interactions of RECQ Helicases”.

Synthetic Lethal Interactions of RECQ Helicases

Trends in cancer(2020)10.1016/j.trecan.2020.09.001

N/A

1.1DataRank · unranked

30 citations

Srijita Dhar, Sanket Awate, Robert M. Brosh, Arindam Datta

Repeat expansions confer WRN dependence in microsatellite-unstable cancers

Nature(2020)10.1038/s41586-020-2769-8

N/A

0.797DataRank · unranked

202 citations

Sriram Sridharan, William J. Nathan, Anthony Tubbs, Edmond M. Chan, Elsa Callén +28 more

The Processing of Holliday Junctions by BLM and WRN Helicases Is Regulated by p53

Journal of Biological Chemistry(2002)10.1074/jbc.m204111200

N/A

0.732DataRank · unranked

131 citations

Ran Zhang, Xin Wei Wang, Elisa A. Spillare, Steven P. Linke, Deepa Subramanian +12 more

DNA helicases and their roles in cancer

DNA repair(2020)10.1016/j.dnarep.2020.102994

N/A

0.553DataRank · unranked

39 citations

Arindam Datta, Robert M. Brosh, Srijita Dhar

WRN rescues replication forks compromised by a BRCA2 deficiency: Predictions for how inhibition of a helicase that suppresses premature aging tilts the balance to fork demise and chromosomal instability in cancer

BioEssays(2022)10.1002/bies.202200057

N/A

0.459DataRank · unranked

9 citations

Robert M. Brosh, Arindam Datta

The Processing of Holliday Junctions by BLM and WRN Helicases Is Regulated by p53

UNC Libraries(2021)10.17615/cqnc-vc04

N/A

0.425DataRank · unranked

16 citations

Jack D. Griffith, Elisa A. Spillare, Jiang Shen, Robert M. Brosh, Lawrence A. Loeb +12 more

FANCJ compensates for RAP80 deficiency and suppresses genomic instability induced by interstrand cross-links

Nucleic Acids Research(2020)10.1093/nar/gkaa660

N/A

0.360DataRank · unranked

10 citations

Joshua A. Sommers, Arindam Datta, Sumeet U. Nayak, Marina A. Bellani, Olivia Yang +7 more

Special Issue: DNA Helicases: Mechanisms, Biological Pathways, and Disease Relevance

Genes(2021)10.3390/genes12030356

N/A

0.296DataRank · unranked

4 citations

Robert M. Brosh

Frontiers in aging special issue: DNA repair and interventions in aging perspective on “loss of epigenetic information as a cause of mammalian aging”

Frontiers in Aging(2023)10.3389/fragi.2023.1199596

N/A

0.241DataRank · unranked

4 citations

Isabel Beerman, Rafael de Cabo, Robert M. Brosh, Ethan Schaffer

Phosphorylation-Dependent Association of WRN with RPA is Required for Recovery of Replication Forks Stalled at Secondary DNA Structures

bioRxiv (Cold Spring Harbor Laboratory)(2023)10.1101/2023.08.08.552428

N/A

0.104DataRank · unranked

1 citations

Pasquale Valenzisi, Federica Fratini, Tomasz Kulikowicz, Joshua A. Sommers, Flavia Di Feo +7 more

G-Quadruplex Assembly by Ribosomal DNA: Emerging Roles in Disease Pathogenesis and Cancer Biology

Cytogenetic and Genome Research(2021)10.1159/000516394

N/A

0DataRank · unranked

25 citations

Kevin J. Pollock, Karen A. Kormuth, Robert M. Brosh, Arindam Datta

A Partially Functional DNA Helicase II Mutant Defective in Forming Stable Binary Complexes with ATP and DNA: A ROLE FOR HELICASE MOTIF III

UNC Libraries(2021)10.17615/919s-jt02

N/A

0DataRank · unranked

1 citations

Robert M. Brosh, Steven W. Matson

Inhibition of Werner Syndrome Helicase Activity by Benzo[ c ]phenanthrene Diol Epoxide dA Adducts in DNA Is Both Strand-and Stereoisomer-dependent

UNC Libraries(2021)10.17615/hxzq-8544

N/A

0DataRank · unranked

0 citations

Donald M. Jerina, Jane M. Sayer, Robert M. Brosh, Steven W. Matson, Henry C. Driscoll +1 more

A Point Mutation in Escherichia coli DNA Helicase II Renders the Enzyme Nonfunctional in Two DNA Repair Pathways: EVIDENCE FOR INITIATION OF UNWINDING FROM A NICKIN VIVO

UNC Libraries(2021)10.17615/z28f-rd78

N/A

0DataRank · unranked

0 citations

Robert M. Brosh, Steven W. Matson

RECON syndrome is a genome instability disorder caused by mutations in the DNA helicase RECQL1

Journal of Clinical Investigation(2022)10.1172/jci147301

N/A

0DataRank · unranked

42 citations

Satpal S. Jhujh, Srijita Dhar, Joshua A. Sommers, Arindam Datta, Gabriel M. C. Longo +19 more

WRN helicase safeguards deprotected replication forks in BRCA2-mutated cancer cells

Nature Communications(2021)10.1038/s41467-021-26811-w

N/A

0DataRank · unranked

51 citations

Kajal Biswas, Joshua A. Sommers, Haley Thompson, Sanket Awate, Claudia M. Nicolae +6 more

DNA fiber analyses to study functional importance of helicases and associated factors during replication stress

Methods in enzymology on CD-ROM/Methods in enzymology(2022)10.1016/bs.mie.2022.04.003

N/A

0DataRank · unranked

1 citations

Robert M. Brosh, Arindam Datta

Ageing Research Reviews Special Issue dedicated to women in aging research

Ageing Research Reviews(2022)10.1016/j.arr.2022.101589

N/A

0DataRank · unranked

2 citations

Robert M. Brosh, Nicole Noren Hooten

Methods special issue: DNA and RNA helicases

Methods(2022)10.1016/j.ymeth.2022.07.010

N/A

0DataRank · unranked

0 citations

Robert M. Brosh

Biochemical analysis of SARS-CoV-2 Nsp13 helicase implicated in COVID-19 and factors that regulate its catalytic functions

Journal of Biological Chemistry(2023)10.1016/j.jbc.2023.102980

N/A

0DataRank · unranked

39 citations

Lorin N. Loftus, Martin P. Jones, Rebecca A. Lee, Caitlin E. Haren, Adaira J Dumm +2 more

Discovery of a new hereditary RECQ helicase disorder RECON syndrome positions the replication stress response and genome homeostasis as centrally important processes in aging and age-related disease

Ageing Research Reviews(2023)10.1016/j.arr.2023.101887

N/A

0DataRank · unranked

5 citations

Joshua A. Sommers, Satpal S. Jhujh, Tamar Harel, Grant S. Stewart, Robert M. Brosh +1 more

Editorial: DNA repair and interventions in aging

Frontiers in Aging(2023)10.3389/fragi.2023.1306463

N/A

0DataRank · unranked

1 citations

Alexey Moskalev, Vera Gorbunova, Robert M. Brosh

Replication stress as a driver of cellular senescence and aging

Communications Biology(2024)10.1038/s42003-024-06263-w

N/A

0DataRank · unranked

56 citations

Ethan Schaffer, Kathleen F. Fuchs, Arindam Datta, Robert M. Brosh, Lauren M. Herr

Purification and biochemical characterization of the G4 resolvase and DNA helicase FANCJ

Methods in enzymology on CD-ROM/Methods in enzymology(2024)10.1016/bs.mie.2023.12.006

N/A

0DataRank · unranked

1 citations

Joshua A. Sommers, Kathleen F. Fuchs, Yuliang Wu, Robert M. Brosh, Tomasz Kulikowicz

Phosphorylation-dependent WRN-RPA interaction promotes recovery of stalled forks at secondary DNA structure

Nature Communications(2025)10.1038/s41467-025-55958-z

N/A

0DataRank · unranked

13 citations

Pasquale Valenzisi, Flavia Di Feo, Federica Fratini, Tomasz Kulikowicz, Joshua A. Sommers +8 more

SARS-CoV-2 point mutations are over-represented in terminal loops of RNA stem-loop structures that can be resolved by Nsp13 helicase in a unique manner with respect to nucleotide dependence

Nucleic Acids Research(2025)10.1093/nar/gkaf447

N/A

0DataRank · unranked

5 citations

Andrew Y Zheng, Thomas Bütler, Tomasz Kulikowicz, Joe C George, Pierce T Bombard +4 more

DNA2 and MSH2 activity collectively mediate chemically stabilized G4 for efficient telomere replication

bioRxiv (Cold Spring Harbor Laboratory)(2025)10.1101/2025.04.04.647332

N/A

0DataRank · unranked

0 citations

Tingting Zhou, R. Steven Esworthy, Changxian Shen, Helen Liu, Jessica D. Hess +17 more

Discovery of thiacyanine dyes as a new class of potent coronavirus inhibitors that suppress viral RNA synthesis

Journal of Biological Chemistry(2025)10.1016/j.jbc.2025.110547

N/A

0DataRank · unranked

0 citations

Valerie Altouma, Joshua A. Sommers, Adaira J Dumm, Debbie R. Kennedy, Hongjie Xia +14 more

An emerging picture of FANCJ’s role in G4 resolution to facilitate DNA replication

NAR Cancer(2021)10.1093/narcan/zcab034

N/A

0DataRank · unranked

23 citations

Yuliang Wu, Robert M. Brosh

Mitochondrial genetic variation is enriched in G-quadruplex regions that stall DNA synthesis in vitro

Human Molecular Genetics(2020)10.1093/hmg/ddaa043

N/A

0DataRank · unranked

60 citations

Katrina N. Estep, Joshua A. Sommers, Robert W. Maul, Ann Zenobia Moore, Stefania Bandinelli +16 more

DNA polymerase β outperforms DNA polymerase γ in key mitochondrial base excision repair activities

DNA repair(2021)10.1016/j.dnarep.2021.103050

N/A

0DataRank · unranked

13 citations

Stephanie L. Baringer, Tomasz Kulikowicz, Joshua A. Sommers, Deborah L. Croteau, Robert M. Brosh +2 more

Biochemical analysis of DNA synthesis blockage by G-quadruplex structure and bypass facilitated by a G4-resolving helicase

Methods(2021)10.1016/j.ymeth.2021.12.005

N/A

0DataRank · unranked

3 citations

Katrina N. Estep, Robert W. Maul, Robert M. Brosh, Joshua A. Sommers