J. Mark Brown

Also affiliated with Cleveland Clinic Lerner College of Medicine, Cleveland Research (United States), Imperial College London

Biochemistry, Genetics and Molecular BiologyMedicine

Pilot corpus only

This score is computed over theSindex pilot corpus and does not cover the full scientific literature. Scores are relative to papers we have ingested — papers, authors, and institutions outside the pilot are not represented. Methodology.

Top 100%percentile

0Author DataRank

Indexed papers

0in pilot corpus

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Papers

Driven by 66 papers. Top paper: “Gut Microbiota–Derived Trimethylamine N-Oxide Contributes to Abdominal Aortic Aneurysm Through Inflammatory and Apoptotic Mechanisms”.

Gut Microbiota–Derived Trimethylamine N-Oxide Contributes to Abdominal Aortic Aneurysm Through Inflammatory and Apoptotic Mechanisms

Circulation(2023)10.1161/circulationaha.122.060573

N/A

2.8DataRank · unranked

153 citations

Kelsey A. Conrad, Xinmin S. Li, Zeneng Wang, Robert N. Helsley, Rebecca C. Schugar +22 more

Gut Microbial Metabolite TMAO Enhances Platelet Hyperreactivity and Thrombosis Risk

UNC Libraries(2020)10.17615/vrx4-j764

N/A

1.9DataRank · unranked

62 citations

Elin Org, Joseph A. DiDonato, R. Balfour Sartor, W. H. Wilson Tang, Roy L. Silverstein +13 more

Gut microbe-targeted choline trimethylamine lyase inhibition improves obesity via rewiring of host circadian rhythms

eLife(2022)10.7554/elife.63998

N/A

1.8DataRank · unranked

71 citations

Christy Gliniak, Lucas J. Osborn, William J. Massey, Naseer Sangwan, Anthony Horak +28 more

Gut microbial trimethylamine is elevated in alcohol-associated hepatitis and contributes to ethanol-induced liver injury in mice

eLife(2022)10.7554/elife.76554

N/A

1.3DataRank · unranked

56 citations

Tatsunori Miyata, Anagha Kadam, Venkateshwari Varadharajan, Naseer Sangwan, Emily Huang +31 more

Obesity-Dependent Adipokine Chemerin Suppresses Fatty Acid Oxidation to Confer Ferroptosis Resistance

Cancer Discovery(2021)10.1158/2159-8290.cd-20-1453

N/A

0.701DataRank · unranked

106 citations

Iqbal Mahmud, Flavia Fontanesi, Michelle Puchowicz, Chase Neumann, Anthony J. Griswold +8 more

Identification of essential genes for Escherichia coli aryl polyene biosynthesis and function in biofilm formation

npj Biofilms and Microbiomes(2021)10.1038/s41522-021-00226-3

N/A

0.680DataRank · unranked

92 citations

Lucas J. Osborn, Rachel L. Markley, Elizabeth A. McManus, Anagha Kadam, Karlee Schultz +5 more

The Gut Microbial Endocrine Organ in Type 2 Diabetes

Endocrinology(2020)10.1210/endocr/bqaa235

N/A

0.612DataRank · unranked

58 citations

J. Mark Brown, William J. Massey

Tumor cell–derived spermidine promotes a protumorigenic immune microenvironment in glioblastoma via CD8+ T cell inhibition

Journal of Clinical Investigation(2024)10.1172/jci177824

N/A

0.571DataRank · unranked

19 citations

Juyeun Lee, Ellen S. Hong, Julia L Beilis, Sahil Dayal, Emily Wesley +21 more

Alcohol-induced gut microbial reorganization and associated overproduction of phenylacetylglutamine promotes cardiovascular disease

Nature Communications(2024)10.1038/s41467-024-55084-2

N/A

0.556DataRank · unranked

19 citations

Min Gu, Aline Zaparte, Xiaoming Fu, K. Mahen, Marko Mrdjen +22 more

Gut microbe-generated phenylacetylglutamine is an endogenous allosteric modulator of β2-adrenergic receptors

Nature Communications(2024)10.1038/s41467-024-50855-3

N/A

0.553DataRank · unranked

39 citations

Valentin Gogonea, Wendy E. Sweet, Maradumane L. Mohan, Khuraijam Dhanachandra Singh, James T. Anderson +13 more

Late-life intermittent fasting decreases aging-related frailty and increases renal hydrogen sulfide production in a sexually dimorphic manner

GeroScience(2021)10.1007/s11357-021-00330-4

N/A

0.553DataRank · unranked

39 citations

Nazmin Bithi, Christopher Link, Jie Yang, Rebecca C. Schugar, Natalia C. Llarena +3 more

Membrane-bound O-acyltransferase 7 (MBOAT7)-driven phosphatidylinositol remodeling in advanced liver disease

Journal of Lipid Research(2022)10.1016/j.jlr.2022.100234

N/A

0.520DataRank · unranked

31 citations

William J. Massey, J. Mark Brown, Venkateshwari Varadharajan

MBOAT7-driven phosphatidylinositol remodeling promotes the progression of clear cell renal carcinoma

Molecular Metabolism(2020)10.1016/j.molmet.2020.01.011

N/A

0.505DataRank · unranked

28 citations

Daniel J. Silver, Venkateshwari Varadharajan, Renliang Zhang, C. Alicia Traughber, Christopher G. Przybycin +6 more

Circulating Gut Microbe-Derived Metabolites Are Associated with Hepatocellular Carcinoma

Biomedicines(2024)10.3390/biomedicines12091946

N/A

0.477DataRank · unranked

23 citations

Chase J. Wehrle, Zeneng Wang, Jennifer Wilcox, Vinayak Uppin, Venkateshwari Varadharajan +11 more

Hepatobiliary malignancies have distinct peripheral myeloid-derived suppressor cell signatures and tumor myeloid cell profiles

Scientific Reports(2020)10.1038/s41598-020-75881-1

N/A

0.470DataRank · unranked

22 citations

Adam Lauko, Gustavo Roversi, Emily Serbinowski, Lou‐Anne Acevedo‐Moreno, Christopher Lanigan +11 more

A surgical method for continuous intraportal infusion of gut microbial metabolites in mice

JCI Insight(2021)10.1172/jci.insight.145607

N/A

0.406DataRank · unranked

14 citations

Lucas J. Osborn, Kevin Fung, William J. Massey, Anthony Horak, Federico Aucejo +6 more

Metaorganismal choline metabolism shapes olfactory perception

Journal of Biological Chemistry(2023)10.1016/j.jbc.2023.105299

N/A

0.396DataRank · unranked

13 citations

Kristen Kay, Thomas C. Jaramillo, Anthony Horak, Shijie Cao, Lucas J. Osborn +12 more

TLR2 regulates hair follicle cycle and regeneration via BMP signaling

eLife(2023)10.7554/elife.89335

N/A

0.359DataRank · unranked

6 citations

Irina Zhevlakova, Xiaoxia Z. West, Detao Gao, Rakhilya Murtazina, Anthony Horak +5 more

Hepatocyte activity of the cholesterol sensor smoothened regulates cholesterol and bile acid homeostasis in mice

iScience(2021)10.1016/j.isci.2021.103089

N/A

0.345DataRank · unranked

9 citations

Seh‐Hoon Oh, Linda Tang, Stephanie Zhang, Amanda L. Brown, Venkateshwari Varadharajan +6 more

Increased Cellular Free Cholesterol in Macrophage-specific Abca1 Knock-out Mice Enhances Pro-inflammatory Response of Macrophages

UNC Libraries(2020)10.17615/db7s-jw23

N/A

0.345DataRank · unranked

9 citations

Ji Young Lee, Jenelle M. Timmins, Elena Boudyguina, Nobuyo Maeda, Anny Mulya +7 more

The nonvesicular sterol transporter Aster-C plays a minor role in whole body cholesterol balance

Frontiers in Physiology(2024)10.3389/fphys.2024.1371096

N/A

0.269DataRank · unranked

5 citations

Rachel C. Hohe, Shijie Cao, Bryan M. Jung, Anthony Horak, Iyappan Ramachandiran +19 more

Disruption of the Gut Microbiota Attenuates Epithelial Ovarian Cancer Sensitivity to Cisplatin Therapy

Research Square(2021)10.21203/rs.3.rs-80626/v2

N/A

0.165DataRank · unranked

2 citations

Emily Esakov, Chad Braley, Lexie Trestan, Zahraa Alali, Defne Bayık +14 more

Metabolic effects of duodenojejunal bypass surgery in a rat model of type 1 diabetes

Surgical Endoscopy(2020)10.1007/s00464-020-07741-y

N/A

0.165DataRank · unranked

2 citations

Rickesha Wilson, Gautam Sharma, Suriya Punchai, Ricard Corcelles, Dvir Froylich +8 more

A Novel Surgical Method for Continuous Intra-Portal Infusion of Gut Microbial Metabolites in Mice

bioRxiv (Cold Spring Harbor Laboratory)(2020)10.1101/2020.10.29.360628

N/A

0.104DataRank · unranked

1 citations

Lucas J. Osborn, Kevin Fung, Federico Aucejo, Ibrahim Choucair, Beckey DeLucia +4 more

Loss of Carnitine Palmitoyltransferase 1a Reduces Docosahexaenoic Acid-Containing Phospholipids and Drives Sexually Dimorphic Liver Disease in Mice

bioRxiv (Cold Spring Harbor Laboratory)(2023)10.1101/2023.08.17.553705

N/A

0.104DataRank · unranked

1 citations

Corissa Cady, Nikitha Dharanipragada, Anna E. Mead, Zachary A. Kipp, Evelyn Bates +15 more

Predicting cardiovascular disease risk from gut microbial genes

mBio(2023)10.1128/mbio.01970-23

N/A

0DataRank · unranked

4 citations

J. Mark Brown, Jan Claesen

Tumor cell-derived spermidine promotes a pro-tumorigenic immune microenvironment in glioblastoma via CD8+ T cell inhibition

bioRxiv (Cold Spring Harbor Laboratory)(2023)10.1101/2023.11.14.567048

N/A

0DataRank · unranked

5 citations

Juyeun Lee, Ellen S. Hong, Julia L Beilis, Sahil Dayal, Emily Wesley +21 more

TLR2 Regulates Hair Follicle Cycle and Regeneration via BMP Signaling

bioRxiv (Cold Spring Harbor Laboratory)(2023)10.1101/2023.08.14.553236

N/A

0DataRank · unranked

2 citations

Irina Zhevlakova, Xiaoxia Z. West, Detao Gao, Rakhylia Murtazina, Anthony Horak +5 more

Membrane Bound O-Acyltransferase 7 (MBOAT7) Shapes Lysosomal Lipid Homeostasis and Function to Control Alcohol-Associated Liver Injury

bioRxiv (Cold Spring Harbor Laboratory)(2023)10.1101/2023.09.26.559533

N/A

0DataRank · unranked

1 citations

Iyappan Ramachandiran, William J. Massey, Raghav Jain, Rakhee Banerjee, Anthony Horak +19 more

TLR2 Regulates Hair Follicle Cycle and Regeneration via BMP Signaling

(2023)10.7554/elife.89335.1

N/A

0DataRank · unranked

0 citations

Irina Zhevlakova, Xiaoxia Z. West, Detao Gao, Rakhylia Murtazina, Anthony Horak +5 more

Joint Public Review: TLR2 Regulates Hair Follicle Cycle and Regeneration via BMP Signaling

(2023)10.7554/elife.89335.1.sa0

N/A

0DataRank · unranked

0 citations

Irina Zhevlakova, Xiaoxia Z. West, Detao Gao, Rakhylia Murtazina, Anthony Horak +5 more

Membrane Bound O-Acyltransferase 7 (MBOAT7) Shapes Lysosomal Lipid Homeostasis and Function to Control Alcohol-Associated Liver Injury

(2023)10.7554/elife.92243.1

N/A

0DataRank · unranked

0 citations

Iyappan Ramachandiran, William J. Massey, Raghav Jain, Rakhee Banerjee, Anthony Horak +19 more

Creeping Fat–Derived Free Fatty Acids Induce Hyperplasia of Intestinal Muscularis Propria Muscle Cells: A Novel Link Between Fat and Intestinal Stricture Formation in Crohn’s Disease

Gastroenterology(2024)10.1053/j.gastro.2024.10.034

N/A

0DataRank · unranked

21 citations

Ren Mao, Thi Hong Nga Le, Gail West, Venkateshwari Varadharajan, Rakhee Banerjee +32 more

TLR2 regulates hair follicle cycle and regeneration via BMP signaling

eLife(2024)10.7554/elife.89335.3

N/A

0DataRank · unranked

12 citations

Irina Zhevlakova, Xiaoxia Z. West, Detao Gao, Rakhilya Murtazina, Anthony Horak +5 more

The pyruvate dehydrogenase kinase inhibitor dichloroacetate mitigates alcohol-induced hepatic inflammation and metabolic disturbances in mice

Hepatology Communications(2024)10.1097/hc9.0000000000000547

N/A

0DataRank · unranked

2 citations

Emily Huang, Megan R. McMullen, Vaibhav Singh, Marko Mrdjen, Annette Bellar +8 more

Integrated Multiomics Analyses of the Molecular Landscape of Sarcopenia in Alcohol‐Related Liver Disease

Journal of Cachexia Sarcopenia and Muscle(2025)10.1002/jcsm.13818

N/A

0DataRank · unranked

5 citations

Pugazhendhi Kannan, Saurabh Mishra, Annette Bellar, Vandana Agrawal, Grahame J. Kidd +10 more

The Lipid Hydrolase ABHD6 is a Therapeutic Target in Metabolic Dysfunction-Associated Steatotic Liver Disease (MASLD)-Related Hepatocellular Carcinoma

bioRxiv (Cold Spring Harbor Laboratory)(2025)10.1101/2025.07.29.667509

N/A

0DataRank · unranked

1 citations

William J. Massey, Kevin Fung, Venkateshwari Varadharajan, Iyappan Ramachandiran, Rakhee Banerjee +28 more

Gut Microbe-Derived Trimethylamine Shapes Circadian Rhythms Through the Host Receptor TAAR5

bioRxiv (Cold Spring Harbor Laboratory)(2025)10.1101/2025.04.03.647082

N/A

0DataRank · unranked

0 citations

William J. Massey, Danny Orabi, Amanda L. Brown, Thomas C. Jaramillo, Amy Burrows +22 more

Gut Microbe-Derived N -Acyl Serinol Lipids Shape Host Postprandial Metabolic Homeostasis

bioRxiv (Cold Spring Harbor Laboratory)(2025)10.1101/2025.04.11.648385

N/A

0DataRank · unranked

0 citations

K. Mahen, William J. Massey, Venkateshwari Varadharajan, Amy Burrows, Anthony Horak +22 more

Gut microbe-derived trimethylamine shapes circadian rhythms through the host receptor TAAR5

eLife(2025)10.7554/elife.107037

N/A

0DataRank · unranked

0 citations

William J. Massey, Danny Orabi, Amanda L Brown, Thomas C. Jaramillo, Amy Burrows +22 more

Bile acids profile, histopathological indices and genetic variants for non-alcoholic fatty liver disease progression

Metabolism(2020)10.1016/j.metabol.2020.154457

N/A

0DataRank · unranked

143 citations

Ibrahim Choucair, Zeneng Wang, Ina Nemet, Lin Li, Janet Gukasyan +11 more

Microbe-derived cyclopropane lipids activate host nuclear receptors

Journal of Lipid Research(2025)10.1016/j.jlr.2025.100923

N/A

0DataRank · unranked

0 citations

J. Mark Brown, William J. Massey

IL-1 induces mitochondrial translocation of IRAK2 to suppress oxidative metabolism in adipocytes

Nature Immunology(2020)10.1038/s41590-020-0750-1

N/A

0DataRank · unranked

58 citations

Han Wang, Minjia Yu, Rebecca C. Schugar, Qian Wen, Fangqiang Tang +17 more

Hepsin enhances liver metabolism and inhibits adipocyte browning in mice

Proceedings of the National Academy of Sciences(2020)10.1073/pnas.1918445117

N/A

0DataRank · unranked

38 citations

Jianhao Peng, Hao Wang, Wei Zhang, J. Mark Brown, Yiqing Zhou +2 more

Altered lipid metabolism marks glioblastoma stem and non-stem cells in separate tumor niches

bioRxiv (Cold Spring Harbor Laboratory)(2020)10.1101/2020.09.20.304964

N/A

0DataRank · unranked

10 citations

Anthony D. Gromovsky, James S. Hale, Arnon Møldrup Knudsen, Briana C. Prager, Lisa C. Wallace +9 more

Identification of essential genes for Escherichia coli aryl polyene biosynthesis and function in biofilm formation

bioRxiv (Cold Spring Harbor Laboratory)(2020)10.1101/2020.04.22.055939

N/A

0DataRank · unranked

6 citations

Lucas J. Osborn, Rachel L. Markley, Elizabeth A. McManus, Anagha Kadam, Karlee Schultz +5 more

Gut Microbe-Targeted Choline Trimethylamine Lyase Inhibition Improves Obesity Via Rewiring of Host Circadian Rhythms

bioRxiv (Cold Spring Harbor Laboratory)(2020)10.1101/2020.12.04.411546

N/A

0DataRank · unranked

2 citations

Christy Gliniak, Robert N. Helsley, Amanda L. Brown, Amy Burrows, Chelsea Finney +21 more

Disruption of the gut microbiota attenuates epithelial ovarian cancer sensitivity to cisplatin therapy

bioRxiv (Cold Spring Harbor Laboratory)(2020)10.1101/2020.06.16.155226

N/A

0DataRank · unranked

1 citations

Emily Esakov, Chad Braley, Lexie Trestan, Zahraa Alali, Defne Bayık +14 more

Cancer Stem Cell Enrichment and Metabolic Substrate Adaptability are Driven by Hydrogen Sulfide Suppression in Glioblastoma

bioRxiv (Cold Spring Harbor Laboratory)(2020)10.1101/2020.03.08.982116

N/A

0DataRank · unranked

0 citations

Gustavo Roversi, Nazmin Bithi, Chase Neumann, Katie Troike, Grace K. Ahuja +5 more

Flavin containing monooxygenase 3 exerts broad effects on glucose and lipid metabolism and atherosclerosis

UNC Libraries(2020)10.17615/z51w-sj48

N/A

0DataRank · unranked

0 citations

Sarada Charugundla, Nam Che, Aldons J. Lusis, Diana M. Shih, Thomas Q. de Aguiar Vallim +10 more

Altered lipid metabolism marks glioblastoma stem and non-stem cells in separate tumor niches

Acta Neuropathologica Communications(2021)10.1186/s40478-021-01205-7

N/A

0DataRank · unranked

125 citations

Anthony D. Gromovsky, James S. Hale, Arnon Møldrup Knudsen, Briana C. Prager, Lisa C. Wallace +8 more

Severe consequences of a high-lipid diet include hydrogen sulfide dysfunction and enhanced aggression in glioblastoma

Journal of Clinical Investigation(2021)10.1172/jci138276

N/A

0DataRank · unranked

55 citations

Gustavo Roversi, Nazmin Bithi, Sabrina Wang, Katie Troike, Chase Neumann +6 more

Salivary metabolites are promising non‐invasive biomarkers of hepatocellular carcinoma and chronic liver disease

Liver Cancer International(2021)10.1002/lci2.25

N/A

0DataRank · unranked

32 citations

Alejandro I. Rodarte, Shirin Siddiqi, Amika Moro, Lou‐Anne Acevedo‐Moreno, J. Mark Brown +4 more

Microbial Flavonoid Metabolism: A Cardiometabolic Disease Perspective

Annual Review of Nutrition(2021)10.1146/annurev-nutr-120420-030424

N/A

0DataRank · unranked

31 citations

Jan Claesen, J. Mark Brown, Lucas J. Osborn

A gut microbial metabolite of dietary polyphenols reverses obesity-driven hepatic steatosis

bioRxiv (Cold Spring Harbor Laboratory)(2021)10.1101/2021.09.16.460661

N/A

0DataRank · unranked

6 citations

Karlee Schultz, William J. Massey, Beckey DeLucia, Ibrahim Choucair, Venkateshwari Varadharajan +15 more

A gut microbial metabolite of dietary polyphenols reverses obesity-driven hepatic steatosis

Proceedings of the National Academy of Sciences(2022)10.1073/pnas.2202934119

N/A

0DataRank · unranked

77 citations

Karlee Schultz, William J. Massey, Beckey DeLucia, Ibrahim Choucair, Venkateshwari Varadharajan +17 more

Flavin-Containing Monooxygenase 3 (FMO3) Is Critical for Dioxin-Induced Reorganization of the Gut Microbiome and Host Insulin Sensitivity

Metabolites(2022)10.3390/metabo12040364

N/A

0DataRank · unranked

25 citations

Lucas J. Osborn, Rakhee Banerjee, Anthony Horak, Kevin Fung, Danny Orabi +5 more

Excess Growth Hormone Alters the Male Mouse Gut Microbiome in an Age-dependent Manner

Endocrinology(2022)10.1210/endocr/bqac074

N/A

0DataRank · unranked

16 citations

J. A. Young, Zachary Jackson, Joshua Busken, Jaycie Kuhn, Maria Onusko +7 more

Salivary miRNAs as non-invasive biomarkers of hepatocellular carcinoma: a pilot study

PeerJ(2022)10.7717/peerj.12715

N/A

0DataRank · unranked

15 citations

Galen Miller‐Atkins, Amika Moro, Alejandro I. Rodarte, Shirin Siddiqi, Lou‐Anne Acevedo‐Moreno +5 more

Gut Microbial Trimethylamine is Elevated in Alcohol-Associated Hepatitis and Contributes to Ethanol-Induced Liver Injury in Mice

bioRxiv (Cold Spring Harbor Laboratory)(2022)10.1101/2021.12.31.474633

N/A

0DataRank · unranked

8 citations

Tatsunori Miyata, Anagha Kadam, Venkateshwari Varadharajan, Naseer Sangwan, Emily Huang +31 more

Strain dropouts reveal interactions that govern the metabolic output of the gut microbiome

Cell(2023)10.1016/j.cell.2023.05.037

N/A

0DataRank · unranked

80 citations

Lucas J. Osborn, Sunit Jain, Xiandong Meng, Allison M. Weakley, Yan Jia +17 more

MMD collaborates with ACSL4 and MBOAT7 to promote polyunsaturated phosphatidylinositol remodeling and susceptibility to ferroptosis

Cell Reports(2023)10.1016/j.celrep.2023.113023

N/A

0DataRank · unranked

59 citations

Jamie Snider, Venkateshwari Varadharajan, Iyappan Ramachandiran, Amy Deik, Zon Weng Lai +16 more

Loss of carnitine palmitoyltransferase 1a reduces docosahexaenoic acid-containing phospholipids and drives sexually dimorphic liver disease in mice

Molecular Metabolism(2023)10.1016/j.molmet.2023.101815

N/A

0DataRank · unranked

18 citations

Corissa Cady, Nikitha Dharanipragada, Anna E. Mead, Zachary A. Kipp, Evelyn Bates +15 more

MBOAT7-driven lysophosphatidylinositol acylation in adipocytes contributes to systemic glucose homeostasis

Journal of Lipid Research(2023)10.1016/j.jlr.2023.100349

N/A

0DataRank · unranked

19 citations

Venkateshwari Varadharajan, Rakhee Banerjee, Amanda L. Brown, Anthony Horak, Rachel C. Hohe +11 more

Membrane-bound O-acyltransferase 7 (MBOAT7) shapes lysosomal lipid homeostasis and function to control alcohol-associated liver injury

eLife(2023)10.7554/elife.92243

N/A

0DataRank · unranked

9 citations

Iyappan Ramachandiran, William J. Massey, Raghav Jain, Rakhee Banerjee, Anthony Horak +19 more

The MIF promoter SNP rs755622 is associated with immune activation in glioblastoma

JCI Insight(2023)10.1172/jci.insight.160024

N/A

0DataRank · unranked

6 citations

Matthew M. Grabowski, Balint Otvos, Defne Bayık, Wesley Wang, Ajay Zalavadia +25 more