Pengda Liu

University of North Carolina at Chapel Hill

Biochemistry, Genetics and Molecular Biology

Pilot corpus only

This score is computed over theSindex pilot corpus and does not cover the full scientific literature. Scores are relative to papers we have ingested — papers, authors, and institutions outside the pilot are not represented. Methodology.

Top 100%percentile

0Author DataRank

Indexed papers

0in pilot corpus

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Papers

Driven by 28 papers. Top paper: “Cytosolic DNA sensing by cGAS: regulation, function, and human diseases”.

Cytosolic DNA sensing by cGAS: regulation, function, and human diseases

Signal Transduction and Targeted Therapy(2021)10.1038/s41392-021-00554-y

N/A

5.6DataRank · unranked

252 citations

Pengda Liu, Le Yu

SPOP and OTUD7A Control EWS–FLI1 Protein Stability to Govern Ewing Sarcoma Growth

Advanced Science(2021)10.1002/advs.202004846

N/A

0.606DataRank · unranked

56 citations

Jianfeng Chen, Yao Jiang, Ying Wang, Tamara Vital, Jiaming Zhang +9 more

Potent and selective SETDB1 covalent negative allosteric modulator reduces methyltransferase activity in cells

Nature Communications(2025)10.1038/s41467-025-57005-3

N/A

0.330DataRank · unranked

8 citations

Devan J. Shell, Madhushika Silva, Yu Deng, Fengling Li, Magdalena M. Szewczyk +21 more

Molecular glue degrader function of SPOP inhibitors enhances STING-dependent immunotherapy efficacy in melanoma models

Journal of Clinical Investigation(2025)10.1172/jci191772

N/A

0.269DataRank · unranked

5 citations

Xin Zhou, Max Xu, Jianfeng Chen, Kevin Robertson, Gatphan Atassi +6 more

The Rab18/Ras/ERK/FosB/MMP3 Signaling Pathway Mediates Cell Migration Regulation by 2′3′-cGAMP

International Journal of Molecular Sciences(2025)10.3390/ijms26125758

N/A

0.165DataRank · unranked

2 citations

Runjie Yuan, Pengda Liu, Yu Deng

STING Suppresses Mitochondrial VDAC2 to Govern RCC Growth Independent of Innate Immunity

Advanced Science(2022)10.1002/advs.202203718

N/A

0DataRank · unranked

63 citations

Xin Zhou, Hongwei Du, Erica W. Cloer, Jiaming Zhang, Mei Liu +9 more

Post-Translational Modifications of Proteins in Cytosolic Nucleic Acid Sensing Signaling Pathways

Frontiers in Immunology(2022)10.3389/fimmu.2022.898724

N/A

0DataRank · unranked

17 citations

Ying Wang, Lupeng Li, Edward A. Miao, Pengda Liu, Yu Deng

Post-Translational Modifications of Proteins in Cytosolic Nucleic Acid Sensing Signaling Pathways

UNC Libraries(2022)10.17615/tg25-s647

N/A

0DataRank · unranked

0 citations

Yu Deng, Edward A. Miao, Ying Wang, Pengda Liu, Lupeng Li

SETDB1 Triple Tudor Domain Ligand, ( R , R )-59, Promotes Methylation of Akt1 in Cells

ACS Chemical Biology(2023)10.1021/acschembio.3c00280

N/A

0DataRank · unranked

15 citations

Yu Deng, Fengling Li, Devan J. Shell, Jacqueline L. Norris‐Drouin, Michael A. Stashko +7 more

AtomNet-Aided OTUD7B Inhibitor Discovery and Validation

Cancers(2023)10.3390/cancers15020517

N/A

0DataRank · unranked

26 citations

Derek L. Bolhuis, Christian Laggner, Deyu Kong, Le Yu, Xiaodong Wang +4 more

Regulation of EWSR1-FLI1 Function by Post-Transcriptional and Post-Translational Modifications

Cancers(2023)10.3390/cancers15020382

N/A

0DataRank · unranked

24 citations

Ian J. Davis, Pengda Liu, Le Yu

AGC kinase inhibitors regulate STING signaling through SGK-dependent and SGK-independent mechanisms

Cell chemical biology(2023)10.1016/j.chembiol.2023.10.008

N/A

0DataRank · unranked

5 citations

Hong Dang, Adam C. Graves, Zhigang Zhang, Jose Torres‐Castillo, Kelin Li +8 more

Streptavidin Promotes DNA Binding and Activation of cGAS to Enhance Innate Immunity

iScience(2020)10.1016/j.isci.2020.101463

N/A

0DataRank · unranked

32 citations

Zhe Ma, Ying Wang, Joshua A. Boyer, Guoxin Ni, Liang Cheng +9 more

Regulation of EWSR1-FLI1 Function by Post-Transcriptional and Post-Translational Modifications

UNC Libraries(2023)10.17615/0qna-fn23

N/A

0DataRank · unranked

0 citations

Le Yu, Ian J. Davis, Pengda Liu

SETDB1 Triple Tudor Domain Ligand, ( R,R )-59, Promotes Methylation of Akt1 in Cells

bioRxiv (Cold Spring Harbor Laboratory)(2023)10.1101/2023.05.10.539986

N/A

0DataRank · unranked

0 citations

Yu Deng, Fengling Li, Devan J. Shell, Jacqueline L. Norris‐Drouin, Michael A. Stashko +7 more

cGAS/STING signalling pathway in senescence and oncogenesis

Seminars in Cancer Biology(2024)10.1016/j.semcancer.2024.08.007

N/A

0DataRank · unranked

48 citations

Pengda Liu, Le Yu

Engineered Cas9 variants bypass Keap1-mediated degradation in human cells and enhance epigenome editing efficiency

Nucleic Acids Research(2024)10.1093/nar/gkae761

N/A

0DataRank · unranked

9 citations

Siyuan Su, Adrian Pickar‐Oliver, Anna M. Chiarella, Quentin Hahn, Dennis Goldfarb +9 more

2′3′-cGAMP interactome identifies 2′3′-cGAMP/Rab18/FosB signaling in cell migration control independent of innate immunity

Science Advances(2024)10.1126/sciadv.ado7024

N/A

0DataRank · unranked

8 citations

Quentin Hahn, Le Yu, Zhichuan Zhu, Joshua A. Boyer, Jian Wang +18 more

Potent and Selective SETDB1 Covalent Negative Allosteric Modulator Reduces Methyltransferase Activity in Cells

bioRxiv (Cold Spring Harbor Laboratory)(2024)10.1101/2024.09.27.615363

N/A

0DataRank · unranked

2 citations

Devan J. Shell, Madhushika Silva, Yu Deng, Fengling Li, Magdalena M. Szewczyk +21 more

Potent and Selective SETDB1 Covalent Negative Allosteric Modulator Reduces Methyltransferase Activity in Cells

Research Square(2024)10.21203/rs.3.rs-5039962/v1

N/A

0DataRank · unranked

0 citations

Mélanie Uguen, Devan J. Shell, Madhushika Silva, Yu Deng, Fengling Li +21 more

OTU deubiquitinases in disease: roles and targeting

Trends in Molecular Medicine(2025)10.1016/j.molmed.2025.05.006

N/A

0DataRank · unranked

6 citations

Pengda Liu, Yu Deng

Phosphorylation of UDP-glucose dehydrogenase increases glycosaminoglycan biosynthesis and promotes tumor cell motility, spheroid growth, and therapeutic resistance

Matrix Biology(2025)10.1016/j.matbio.2025.10.004

N/A

0DataRank · unranked

4 citations

Linlin Ma, Dalton Hilovsky, Brenna M. Zimmer, Emily Allego, Jade Fluharty +9 more

cGAS Inhibits ALDH2 to Suppress Lipid Droplet Function and Regulate MASLD Progression

Advanced Science(2025)10.1002/advs.202508576

N/A

0DataRank · unranked

4 citations

Yu Deng, Jianfeng Chen, Quentin Hahn, David S. Umbaugh, Zhigang Zhang +10 more

Somatic gain-of-function mutations in BUD13 promote oncogenesis by disrupting Fbw7 function

The Journal of Experimental Medicine(2023)10.1084/jem.20222056

N/A

0DataRank · unranked

4 citations

Xinyi Zhang, Xianming Tan, Pengda Liu, Jianfeng Chen

FAM13A Represses AMPK Activity and Regulates Hepatic Glucose and Lipid Metabolism

iScience(2020)10.1016/j.isci.2020.100928

N/A

0DataRank · unranked

24 citations

Yae-Huei Liou, Yujun Li, Lu Gong, Yan Li, Yuan Hao +13 more

Protocol for Monitoring DNA-Triggered cGAS/STING Signaling in Mammalian Cells and Mice

STAR Protocols(2020)10.1016/j.xpro.2020.100171

N/A

0DataRank · unranked

2 citations

Zhe Ma, Blossom Damania, Pengda Liu, Ying Wang

pVHL suppresses kinase activity of Akt in a proline-hydroxylation-dependent manner

UNC Libraries(2020)10.17615/792d-1w31

N/A

0DataRank · unranked

4 citations

Jinfang Zhang, Hiroyuki Inuzuka, Xingnan Zheng, Wenjian Gan, Abhishek A. Chakraborty +13 more

Lenalidomide downregulates ACE2 protein abundance to alleviate infection by SARS-CoV-2 spike protein conditioned pseudoviruses

Signal Transduction and Targeted Therapy(2021)10.1038/s41392-021-00608-1

N/A

0DataRank · unranked

13 citations

Jianfeng Chen, Ying Wang, Lilly Wong, Zhichuan Zhu, Guochun Jiang +2 more