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cGAS Inhibits ALDH2 to Suppress Lipid Droplet Function and Regulate MASLD Progression

Advanced Science(2025)10.1002/advs.202508576Source: DataRank Database

cGAS Inhibits ALDH2 to Suppress Lipid Droplet Function and Regulate MASLD Progression is a research paper published in Advanced Science (2025). On theSindex it has a DataRank of 0. It has been cited 4 times.

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Open Access4 citations

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datarank_citation_only_1hop_v6· scope data_onlyMethodology

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Enrichment:Funding (11 grants)Impact (FWCI 1.59)OA: goldTopics (45)IDs (PubMed, PMC, OpenAlex)Annotations (1)

FAIR Checklist

Context only (not used in score)

Findable (1/2)

Has DOI

Accessible (1/2)

Open Access

Interoperable (0/2)

Reusable (0/3)

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Authors (15)

Yu Deng ORCID,Jianfeng Chen ORCID,Quentin Hahn ORCID,David S. Umbaugh ORCID,Zhigang Zhang ORCID

Live enrichment

PubMed:41042077 PMC:PMC12697864 OpenAlex:https://openalex.org/W4414782450

National Institutes of Health

Grant: CA244825

NCI NIH HHS

Grant: P01 CA019014

NCI NIH HHS

Grant: P30 CA016086

NCI Center Core Support

Grant: CA16086

NCI NIH HHS

Grant: R01 CA244825

NIH R01

Grant: CA291473

NIH R01

Grant: CA019014

Mary Kay Ash Foundation

University of North Carolina at Chapel Hill University Cancer Research Fund

Mary Kay Ash Foundation

University of North Carolina at Chapel Hill University Cancer Research Fund

FWCI

1.59

Citation Percentile

0.8%

Citation Trend

2026

goldLicense: cc-by

journalhttps://doi.org/10.1002/advs.202508576

publisherhttps://doi.org/10.1002/advs.202508576

publisherhttps://advanced.onlinelibrary.wiley.com/doi/pdf/10.1002/advs.202508576

repositoryhttps://pubmed.ncbi.nlm.nih.gov/41042077

repositoryhttps://doaj.org/article/3c19ebaaee0e441a8d6b846234cb0ff9

Fields of Study

interferon and immune responsesImmune Cell Function and InteractionImmune cells in cancerAnimalsAldehyde Dehydrogenase, MitochondrialLipid DropletsMiceNucleotidyltransferasesHumansMice, KnockoutFatty LiverMice, Inbred C57BLDisease ProgressionLiverMaleEndoplasmic Reticulum StressCyclic Guanosine Monophosphate-Adenosine Monophosphate Synthase

MeSH Terms

Aldehyde Dehydrogenase, MitochondrialCyclic Guanosine Monophosphate-Adenosine Monophosphate SynthaseAnimalsFatty LiverHumansLiverMaleMice, Inbred C57BLNucleotidyltransferasesMice, KnockoutDisease ProgressionMiceEndoplasmic Reticulum StressLipid Droplets

Keywords

Lipid dropletALDH2Lipid metabolismInnate immune systemAldehyde dehydrogenaseAcetylationBiogenesisHistoneCytosolHeat shock proteinlipid dropletsHfdCgasMasld

cGAS Inhibits ALDH2 to Suppress Lipid Droplet Function and Regulate MASLD Progression

FAIR Checklist

Authors (15)

Funding (11 grants)

Impact

Open Access

Topics

Annotations (Europe PMC)