Roel G.W. Verhaak

Also affiliated with Yale University, University of New Haven

MedicineBiochemistry, Genetics and Molecular Biology

Pilot corpus only

This score is computed over theSindex pilot corpus and does not cover the full scientific literature. Scores are relative to papers we have ingested — papers, authors, and institutions outside the pilot are not represented. Methodology.

Top 100%percentile

0Author DataRank

Indexed papers

1in pilot corpus

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Why this DataRank?

An author's DataRank is the sum of the DataRanks of all 1 indexed paper attributed to them. A prolific author with many moderate-impact papers can outrank one with a single high-impact paper.

Author scores recompute whenever paper DataRanks are refreshed, so this number lags the underlying paper scores by at most one batch run.

Read the full methodology →

Papers

Driven by 48 papers. Top paper: “Extrachromosomal DNA is associated with oncogene amplification and poor outcome across multiple cancers”.

Extrachromosomal DNA is associated with oncogene amplification and poor outcome across multiple cancers

Nature Genetics(2020)10.1038/s41588-020-0678-2

N/A

9.9DataRank · unranked

641 citations

Nam Nguyen, Kristen M. Turner, Sihan Wu, Amit D. Gujar, Jens Luebeck +15 more

Disruption of chromatin folding domains by somatic genomic rearrangements in human cancer

Nature Genetics(2020)10.1038/s41588-019-0564-y

N/A

5.9DataRank · unranked

312 citations

Victoria T. Le, Sahaana Chandran, Yilong Li, Roel G.W. Verhaak, Rameen Beroukhim +91 more

Somatic mutation distributions in cancer genomes vary with three-dimensional chromatin structure

Nature Genetics(2020)10.1038/s41588-020-0708-0

N/A

3.0DataRank · unranked

124 citations

Victoria T. Le, Justin M. Kim, Sarah Killcoyne, D. A. King, Ya‐Ping Lin +22 more

Homozygous MTAP deletion in primary human glioblastoma is not associated with elevation of methylthioadenosine

Nature Communications(2021)10.1038/s41467-021-24240-3

N/A

2.2DataRank · unranked

55 citations

Jeffrey J. Ackroyd, Victoria C. Yan, Sunada Khadka, Lin Wang, Ko‐Chien Chen +16 more

Integrated Genomic Analysis Identifies Clinically Relevant Subtypes of Glioblastoma Characterized by Abnormalities in PDGFRA, IDH1, EGFR, and NF1

Cancer Cell(2010)10.1016/j.ccr.2009.12.020

N/A

1.3DataRank · unranked

7682 citations

Katherine A. Hoadley, Elizabeth Purdom, Victoria Wang, Yuan Qi, Matthew D. Wilkerson +31 more

SOX2 is an amplified lineage-survival oncogene in lung and esophageal squamous cell carcinomas

Nature Genetics(2009)10.1038/ng.465

N/A

1.0DataRank · unranked

949 citations

Hideo Watanabe, Craig H. Mermel, Soyoung Yu, Sven Perner, So Young Kim +48 more

Glioma progression is shaped by genetic evolution and microenvironment interactions

Cell(2022)10.1016/j.cell.2022.04.038

N/A

0.936DataRank · unranked

511 citations

Kevin C. Johnson, Jan Martinek, Jason T. Huse, MacLean P. Nasrallah, Pieter Wesseling +53 more

Oncogenic extrachromosomal DNA functions as mobile enhancers to globally amplify chromosomal transcription

Cancer Cell(2021)10.1016/j.ccell.2021.03.006

N/A

0.854DataRank · unranked

296 citations

Amit D. Gujar, Chee‐Hong Wong, Harianto Tjong, Chew Yee Ngan, Liang Gong +14 more

Genomic sequencing of colorectal adenocarcinomas identifies a recurrent VTI1A-TCF7L2 fusion

Nature Genetics(2011)10.1038/ng.936

N/A

0.838DataRank · unranked

266 citations

Michael S. Lawrence, Lear E. Brace, Alex H. Ramos, Timothy R. Dreszer, Kristian Cibulskis +37 more

Extrachromosomal DNA in the cancerous transformation of Barrett’s oesophagus

Nature(2023)10.1038/s41586-023-05937-5

N/A

0.789DataRank · unranked

192 citations

Alvin Wei Tian Ng, Patricia C. Galipeau, Xiaohong Li, Carissa A. Sanchez, Annalise Katz‐Summercorn +15 more

Live-Cell Imaging Shows Uneven Segregation of Extrachromosomal DNA Elements and Transcriptionally Active Extrachromosomal DNA Hubs in Cancer

Cancer Discovery(2021)10.1158/2159-8290.cd-21-1376

N/A

0.774DataRank · unranked

173 citations

Amit D. Gujar, Molly Guthrie, Hoon Kim, Dacheng Zhao, Kevin C. Johnson +9 more

Radiotherapy is associated with a deletion signature that contributes to poor outcomes in patients with cancer

Nature Genetics(2021)10.1038/s41588-021-00874-3

N/A

0.772DataRank · unranked

171 citations

Kevin Anderson, Frederick S. Varn, Kevin C. Johnson, Samirkumar B. Amin, Erik P. Sulman +4 more

A modular master regulator landscape controls cancer transcriptional identity

Cell(2021)10.1016/j.cell.2020.11.045

N/A

0.749DataRank · unranked

146 citations

Àlvaro Aytés, Sunny J. Jones, Prem S. Subramaniam, Federico M. Giorgi, Eugene F. Douglass +9 more

Extrachromosomal DNA amplifications in cancer

Nature Reviews Genetics(2022)10.1038/s41576-022-00521-5

N/A

0.736DataRank · unranked

134 citations

Rocío Chamorro González, Anton G. Henssen, Roel G.W. Verhaak, Eunhee Yi

The multilayered transcriptional architecture of glioblastoma ecosystems

Nature Genetics(2025)10.1038/s41588-025-02167-5

N/A

0.686DataRank · unranked

96 citations

Avishay Spitzer, Kevin C. Johnson, Luciano Garofano, Djamel Nehar-Belaid, Noam Galili Darnell +41 more

HUGO Gene Nomenclature Committee (HGNC) recommendations for the designation of gene fusions

Leukemia(2021)10.1038/s41375-021-01436-6

N/A

0.677DataRank · unranked

90 citations

Cristina R. Antonescu, Andrew J. Carroll, Arul M. Chinnaiyan, Ian A. Cree, Nicholas C.P. Cross +12 more

Deciphering the longitudinal trajectories of glioblastoma ecosystems by integrative single-cell genomics

Nature Genetics(2025)10.1038/s41588-025-02168-4

N/A

0.626DataRank · unranked

64 citations

Kevin C. Johnson, Masashi Nomura, Luciano Garofano, Djamel Nehar-Belaid, Noam Galili Darnell +41 more

Correcting the drug development paradigm for glioblastoma requires serial tissue sampling

Nature Medicine(2023)10.1038/s41591-023-02464-8

N/A

0.604DataRank · unranked

55 citations

Kelly Hotchkiss, Ian F. Parney, John de Groot, Solmaz Sahebjam, Nader Sanai +31 more

Extrachromosomal DNA (ecDNA): an origin of tumor heterogeneity, genomic remodeling, and drug resistance

Biochemical Society Transactions(2022)10.1042/bst20221045

N/A

0.538DataRank · unranked

35 citations

Roel G.W. Verhaak, Anton Henssen, Paul S. Mischel, Lauren T. Pecorino

Prognostically relevant gene signatures of high-grade serous ovarian carcinoma

UNC Libraries(2020)10.17615/c9kk-d491

N/A

0.517DataRank · unranked

4 citations

Martin Köbel, Hailei Zhang, Rehan Akbani, Nianxiang Zhang, Katherine A. Hoadley +27 more

Lineage-coupled clonal capture identifies clonal evolution mechanisms and vulnerabilities of BRAFV600E inhibition resistance in melanoma

Cell Discovery(2022)10.1038/s41421-022-00462-7

N/A

0.497DataRank · unranked

9 citations

Yingwen Ding, Ravesanker Ezhilarasan, Tenzin Lhakhang, Qianghu Wang, Jie Yang +8 more

A brave new framework for glioma drug development

The Lancet Oncology(2024)10.1016/s1470-2045(24)00190-6

N/A

0.494DataRank · unranked

26 citations

Philipp Karschnia, Karisa C. Schreck, Marjolein Geurts, Timothy F. Cloughesy, Jason T. Huse +34 more

Central nervous system immune interactome is a function of cancer lineage, tumor microenvironment, and STAT3 expression

JCI Insight(2022)10.1172/jci.insight.157612

N/A

0.494DataRank · unranked

26 citations

Martina Ott, Cynthia Kassab, Arvind Rao, Ganesh Rao, Anantha Marisetty +20 more

A validated integrated clinical and molecular glioblastoma long-term survival-predictive nomogram

Neuro-Oncology Advances(2020)10.1093/noajnl/vdaa146

N/A

0.457DataRank · unranked

20 citations

Tiffany R. Hodges, Nazanin Majd, Kristin Alfaro-Munoz, Wajd N. Al‐Holou, Dima Suki +15 more

Comprehensive and Integrated Genomic Characterization of Adult Soft Tissue Sarcomas

UNC Libraries(2020)10.17615/jcyr-9v75

N/A

0.442DataRank · unranked

18 citations

Candace Shelton, Matthew Meyerson, Carrie Cibulskis, Jia Liu, Joshua Armenia +95 more

Subclonal evolution and expansion of spatially distinct THY1-positive cells is associated with recurrence in glioblastoma

Neoplasia(2023)10.1016/j.neo.2022.100872

N/A

0.434DataRank · unranked

17 citations

Hanxiao Wang, Visweswaran Ravikumar, Sunita Shankar, Morgan Oneka, Ziad Fehmi +16 more

Quality of life after surgery for lower grade gliomas

Cancer(2023)10.1002/cncr.34980

N/A

0.425DataRank · unranked

16 citations

Yilun Wu, Luke Benz, Roel G.W. Verhaak, Bethany M. Kwan, Elizabeth B. Claus +1 more

Longitudinal analysis of diffuse glioma reveals cell state dynamics at recurrence associated with changes in genetics and the microenvironment

bioRxiv (Cold Spring Harbor Laboratory)(2021)10.1101/2021.05.03.442486

N/A

0.406DataRank · unranked

14 citations

Kevin C. Johnson, Taylor Wade, Tathiane M. Malta, Thaís S. Sabedot, Floris P Barthel +26 more

Single-nucleus transcriptomics, pharmacokinetics, and pharmacodynamics of CDK4/6 and mTOR inhibition in a Phase 0/1 trial of recurrent high-grade glioma

Neuro-Oncology(2025)10.1093/neuonc/noaf257

N/A

0.241DataRank · unranked

4 citations

An‐Chi Tien, Jun Jiang, James McNamara, Yu‐Wei Chang, Chelsea Montgomery +17 more

Live-cell imaging shows uneven segregation of extrachromosomal DNA elements and transcriptionally active extrachromosomal DNA clusters in cancer

bioRxiv (Cold Spring Harbor Laboratory)(2020)10.1101/2020.10.20.335216

N/A

0.208DataRank · unranked

3 citations

Amit D. Gujar, Molly Guthrie, Hoon Kim, Kevin C. Johnson, Samirkumar B. Amin +5 more

The epigenetic evolution of gliomas is determined by their IDH1 mutation status and treatment regimen

bioRxiv (Cold Spring Harbor Laboratory)(2021)10.1101/2021.08.09.455687

N/A

0.165DataRank · unranked

2 citations

Thaís S. Sabedot, Indrani Datta, Luciano Garofano, Wies Vallentgoed, Frederick S. Varn +35 more

Engagement Methods in Brain Tumor Genomic Research: Multimethod Comparative Study

Journal of Participatory Medicine(2025)10.2196/68852

N/A

0.104DataRank · unranked

1 citations

Juliana Barnard, Carly Ritger, Laura Helmkamp, Anowara Begum, Sandra Garcia-Hernandez +15 more

GBMdeconvoluteR accurately infers proportions of neoplastic and immune cell populations from bulk glioblastoma transcriptomics data

bioRxiv (Cold Spring Harbor Laboratory)(2022)10.1101/2022.11.19.517187

N/A

0DataRank · unranked

3 citations

Disha Lodha, Steven Pollock, Gemma Hemmings, Martina A. Finetti, Arief Gusnanto +12 more

An integrated genomic analysis identifies clinically relevant subtypes of glioblastoma characterized by abnormalities in PDGFRA, IDH1, EGFR and NF1

UNC Libraries(2020)10.17615/qy3p-zp42

N/A

0DataRank · unranked

0 citations

Richard K. Wilson, Katherine A. Hoadley, Gad Getz, Heidi S. Feiler, Jann N. Sarkaria +28 more

Hemizygous CDKN2A deletion confers worse survival outcomes in IDHmut-noncodel gliomas

Neuro-Oncology(2023)10.1093/neuonc/noad095

N/A

0DataRank · unranked

51 citations

Kevin C. Johnson, Thaís S. Sabedot, Hans Christian Reinhardt, Houtan Noushmehr, Roel G.W. Verhaak +1 more

GBMdeconvoluteR accurately infers proportions of neoplastic and immune cell populations from bulk glioblastoma transcriptomics data

Neuro-Oncology(2023)10.1093/neuonc/noad021

N/A

0DataRank · unranked

28 citations

Disha Lodha, Steven Pollock, Gemma Hemmings, Martina A. Finetti, Arief Gusnanto +12 more

Transformation of quiescent adult oligodendrocyte precursor cells into malignant glioma through a multistep reactivation process

UNC Libraries(2020)10.17615/3152-rw81

N/A

0DataRank · unranked

0 citations

Hui Zong, Oded Foreman, Robert S. McNeill, Akiko Nishiyama, Roel G.W. Verhaak +4 more

Genomic sequencing of colorectal adenocarcinomas identifies a recurrent VTI1A-TCF7L2 fusion

UNC Libraries(2020)10.17615/wq19-7x17

N/A

0DataRank · unranked

0 citations

Adam J. Bass, Alex H. Ramos, Yujin Hoshida, Andrey Sivachenko, Trevor J. Pugh +27 more

Data from Live-Cell Imaging Shows Uneven Segregation of Extrachromosomal DNA Elements and Transcriptionally Active Extrachromosomal DNA Hubs in Cancer

(2023)10.1158/2159-8290.c.6549473.v1

N/A

0DataRank · unranked

0 citations

Amit D. Gujar, Molly Guthrie, Hoon Kim, Dacheng Zhao, Kevin C. Johnson +9 more

2MO Radiotherapy in cancer is associated with a deletion signature that contributes to poor patient outcomes

Annals of Oncology(2020)10.1016/j.annonc.2020.08.2161

N/A

0DataRank · unranked

0 citations

Kevin Anderson, Kevin C. Johnson, Frederick S. Varn, Samirkumar B. Amin, Erik P. Sulman +3 more

DNA methylation classification in diffuse glioma shows little spatial heterogeneity after adjusting for tumor purity

bioRxiv (Cold Spring Harbor Laboratory)(2020)10.1101/2020.03.28.012732

N/A

0DataRank · unranked

1 citations

F.B. Barthel, Kevin Anderson, Kevin C. Johnson, Thomas Koopman, Maqsood Yaqub +15 more

iGLASS: imaging integration into the Glioma Longitudinal Analysis Consortium

Neuro-Oncology(2020)10.1093/neuonc/noaa160

N/A

0DataRank · unranked

20 citations

D. Ryan Ormond, Kristin Alfaro-Munoz, Marion Smits, Lee Alex Donald Cooper, Roel G.W. Verhaak +2 more

Comparative Molecular Life History of Spontaneous Canine and Human Gliomas

Cancer Cell(2020)10.1016/j.ccell.2020.01.004

N/A

0DataRank · unranked

104 citations

Kevin Anderson, C. Elizabeth Boudreau, Emmanuel Martínez-Ledesma, Emre Kocakavuk, Kevin C. Johnson +26 more

Selective Depletion of Cancer Cells with Extrachromosomal DNA via Lentiviral Infection

Cancer Research Communications(2025)10.1158/2767-9764.crc-25-0144

N/A

0DataRank · unranked

1 citations

Amit D. Gujar, Dacheng Zhao, Kentaro Suina, Xue Jin, Katharina Pardon +8 more

Energetics of whole genome doubling and genomic instability

Cancer Letters(2025)10.1016/j.canlet.2025.217878

N/A

0DataRank · unranked

0 citations

Vural Tagal, Samirkumar B. Amin, Samuel F. Bakhoum, Carlo C. Maley, Roel G.W. Verhaak +3 more

PDPN marks a subset of aggressive and radiation-resistant glioblastoma cells

Frontiers in Oncology(2022)10.3389/fonc.2022.941657

N/A

0DataRank · unranked

9 citations

Eskil Eskilsson, Ravesanker Ezhilarasan, Qianghu Wang, Lindsey D. Goodman, Yingwen Ding +13 more

Transcriptional regulatory networks of tumor-associated macrophages that drive malignancy in mesenchymal glioblastoma

Genome biology(2020)10.1186/s13059-020-02140-x

N/A

0DataRank · unranked

110 citations

Nakho Chang, Hye Won Lee, Hee Jin Cho, Michele Ceccarelli, Luigi Cerulo +30 more

Subclonal evolution and expansion of spatially distinct THY1-positive cells is associated with recurrence in glioblastoma

bioRxiv (Cold Spring Harbor Laboratory)(2021)10.1101/2021.09.10.459454

N/A

0DataRank · unranked

0 citations

Hanxiao Wang, Visweswaran Ravikumar, Morgan Oneka, Roel G.W. Verhaak, Hoon Kim +15 more