🏆 Finalist — NIH Data Sharing Index (“S-Index”) Challenge

David M. MacAlpine

Duke Medical Center

ORCID: 0000-0003-3338-8112

Also affiliated with Duke University Hospital

Biochemistry, Genetics and Molecular Biology

Pilot corpus only

This score is computed over theSindex pilot corpus and does not cover the full scientific literature. Scores are relative to papers we have ingested — papers, authors, and institutions outside the pilot are not represented. Methodology.

Top 1%percentile
17.5Author DataRank

Indexed papers

4in pilot corpus
datarank_citation_only_1hop_v6· scope data_onlyMethodology
Why this DataRank?

An author's DataRank is the sum of the DataRanks of all 4 indexed papers attributed to them. A prolific author with many moderate-impact papers can outrank one with a single high-impact paper.

Author scores recompute whenever paper DataRanks are refreshed, so this number lags the underlying paper scores by at most one batch run.

Read the full methodology →

Top data-sharing exemplar

The highest-impact dataset this researcher has shared, ranked by DataRank — the single contribution doing the most to lift their data-sharing standing.

Comprehensive analysis of the chromatin landscape in Drosophila melanogaster

Nature(2010)10.1038/nature09725
Top 2%
8.1DataRank
Top 2%911 citations

Sebastian Will, Yuri B. Schwartz, Aki Minoda, Nicole C. Riddle, Jason Ernst +28 more

Papers

Driven by 19 papers — median percentile 97. Top paper: “Comprehensive analysis of the chromatin landscape in Drosophila melanogaster”.

Comprehensive analysis of the chromatin landscape in Drosophila melanogaster

Nature(2010)10.1038/nature09725
Top 2%
8.1DataRank
Top 2%911 citations

Sebastian Will, Yuri B. Schwartz, Aki Minoda, Nicole C. Riddle, Jason Ernst +28 more

A cis-regulatory map of the Drosophila genome

Nature(2011)10.1038/nature09990
Top 3%
7.0DataRank
Top 3%543 citations

Christopher D. Brown, Christopher Aaron Bristow, Steven W. Miller, Ulrich Wagner, Yanxiao Zhang +40 more

Identification of Functional Elements and Regulatory Circuits by Drosophila modENCODE

Science(2010)10.1126/science.1198374
Top 9%
2.4DataRank
Top 9%1089 citations

Sushmita Roy, Jason Ernst, Peter V. Kharchenko, Yanxiao Zhang, Richard S. Sandstrom +172 more

Unlocking the secrets of the genome

Nature(2009)10.1038/459927a
N/A
1.0DataRank · unranked
822 citations

Susan E. Celniker, Laura A. L. Dillon, Mark B. Gerstein, Kristin C. Gunsalus, Steven Henikoff +11 more

Evolution, biogenesis, expression, and target predictions of a substantially expanded set of Drosophila microRNAs

Genome Research(2007)10.1101/gr.6597907
N/A
0.964DataRank · unranked
617 citations

Alexander Stark, Wendy K. Johnston, Sharon L. R. Kardia, David P. Bartel, David M. MacAlpine +1 more

Comparative analysis of metazoan chromatin organization

Nature(2014)10.1038/nature13415
N/A
0.910DataRank · unranked
429 citations

Youngsook L. Jung, Tao Liu, Burak H. Alver, Soohyun Lee, Kohta Ikegami +83 more

Spt6-Spn1 interaction is required for RNA polymerase II association and precise nucleosome positioning along transcribed genes

Journal of Biological Chemistry(2025)10.1016/j.jbc.2025.108436
N/A
0.233DataRank · unranked
3 citations

Raghuvar Dronamraju, Whitney R. Smith-Kinnaman, Sarah A. Peck Justice, Austin J. Hepperla, Heather K. MacAlpine +5 more

DNA mutagenesis driven by transcription factor competition with mismatch repair

Cell(2025)10.1016/j.cell.2025.07.003
N/A
0.165DataRank · unranked
2 citations

Yuning Zhang, Harshit Sahay, Hana Wasserman, Ariel Afek, Jonathan Williams +11 more

Unlocking the secrets of the genome

UNC Libraries(2020)10.17615/aw2c-np04
N/A
0.154DataRank · unranked
1 citations

Laura A. L. Dillon, Grigorios Georgolopoulos, Kristin C. Gunsalus, Steven Henikoff, Gary H. Karpen +10 more

Heterogeneous polymerase fidelity and mismatch repair bias genome variation and composition

UNC Libraries(2020)10.17615/1sxk-p977
N/A
0DataRank · unranked
0 citations

Scott A. Lujan, Dmitry A. Gordenin, Allan Clark, Ewa P. Malc, Anders R. Clausen +6 more

Cell-Cycle–Dependent Chromatin Dynamics at Replication Origins

Genes(2021)10.3390/genes12121998
N/A
0DataRank · unranked
7 citations

Alexander J. Hartemink, David M. MacAlpine, Yulong Li

Linking the dynamics of chromatin occupancy and transcription with predictive models

Genome Research(2021)10.1101/gr.267237.120
N/A
0DataRank · unranked
12 citations

Heather K. MacAlpine, Vinay Tripuraneni, Sneha Mitra, David M. MacAlpine, Alexander J. Hartemink +1 more

Disruption of origin chromatin structure by helicase activation in the absence of DNA replication

Genes & Development(2021)10.1101/gad.348517.121
N/A
0DataRank · unranked
4 citations

Heather K. MacAlpine, David M. MacAlpine, Rachel A. Hoffman

Linking the dynamics of chromatin occupancy and transcription with predictive models

bioRxiv (Cold Spring Harbor Laboratory)(2020)10.1101/2020.06.28.176545
N/A
0DataRank · unranked
2 citations

Heather K. MacAlpine, Vinay Tripuraneni, Sneha Mitra, David M. MacAlpine, Alexander J. Hartemink +1 more

Spatiotemporal kinetics of CAF-1-dependent chromatin maturation ensures transcription fidelity during S-phase

bioRxiv (Cold Spring Harbor Laboratory)(2023)10.1101/2023.05.25.541209
N/A
0DataRank · unranked
3 citations

Heather K. MacAlpine, Alexander J. Hartemink, David M. MacAlpine, B.J. Chen

Genome-wide nucleosome and transcription factor responses to genetic perturbations reveal chromatin-mediated mechanisms of transcriptional regulation

bioRxiv (Cold Spring Harbor Laboratory)(2024)10.1101/2024.05.24.595391
N/A
0DataRank · unranked
1 citations

Yulong Li, Alexander J. Hartemink, David M. MacAlpine, Kevin Moyung

Methylation of histone H4 lysine 20 by PR-Set7 ensures the integrity of late replicating sequence domains in Drosophila

UNC Libraries(2020)10.17615/kd6e-nm32
N/A
0DataRank · unranked
6 citations

Robert J. Duronio, Robin L. Armstrong, David M. MacAlpine, Yulong Li

Genome-wide nucleosome and transcription factor responses to genetic perturbations reveal chromatin-mediated mechanisms of transcriptional regulation

Genome Research(2025)10.1101/gr.279637.124
N/A
0DataRank · unranked
1 citations

Yulong Li, Heather K. MacAlpine, Alexander J. Hartemink, David M. MacAlpine, Kevin Moyung

Spatiotemporal kinetics of CAF-1-dependent chromatin maturation ensures transcription fidelity during S-phase

Genome Research(2023)10.1101/gr.278273.123
N/A
0DataRank · unranked
9 citations

Heather K. MacAlpine, Alexander J. Hartemink, David M. MacAlpine, B.J. Chen