Yusuf A. Hannun

Also affiliated with Stony Brook University

Biochemistry, Genetics and Molecular Biology

Pilot corpus only

This score is computed over theSindex pilot corpus and does not cover the full scientific literature. Scores are relative to papers we have ingested — papers, authors, and institutions outside the pilot are not represented. Methodology.

Top 100%percentile

0Author DataRank

Indexed papers

0in pilot corpus

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Papers

Driven by 40 papers. Top paper: “A transcriptional network governing ceramide homeostasis establishes a cytokine-dependent developmental process”.

A transcriptional network governing ceramide homeostasis establishes a cytokine-dependent developmental process

Nature Communications(2023)10.1038/s41467-023-42978-w

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0.412DataRank · unranked

10 citations

Abiola Babatunde, Stephanie Qiu, Hamsini Harikumar, Joshua J. Coon, Katherine A. Overmyer +4 more

Expression of Ceramide Synthases in Mice and Their Roles in Regulating Acyl-Chain Sphingolipids: A Framework for Baseline Levels and Future Implications in Aging and Disease

Molecular Pharmacology(2023)10.1124/molpharm.123.000788

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0.360DataRank · unranked

10 citations

Sophia B. Humphrey, Sophia M. Sears, Nicholas A. Hoffman, Andrew Orwick, Mark A. Doll +9 more

Identification of Small-Molecule Inhibitors of Neutral Ceramidase (nCDase) via Target-Based High-Throughput Screening

SLAS DISCOVERY(2020)10.1177/2472555220945283

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0DataRank · unranked

16 citations

Michael V. Airola, Yong‐Mi Choi, Nicolas Coant, Justin M. Snider, Chris Cariello +10 more

Bioactive sphingolipids: Advancements and contributions from the laboratory of Dr. Lina M. Obeid

Cellular Signalling(2020)10.1016/j.cellsig.2020.109875

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0DataRank · unranked

15 citations

María José Hernandez‐Corbacho, Magali Trayssac, Jeffrey L. Stith, Joseph Bonica, Bernandie Jean +6 more

Inhibition of acid ceramidase regulates MHC class II antigen presentation and suppression of autoimmune arthritis

Cytokine(2020)10.1016/j.cyto.2020.155219

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0DataRank · unranked

13 citations

Laela M. Hajiaghamohseni, Xiang Liu, Zdzisław M. Szulc, Aiping Bai, Alicja Bielawska +5 more

Yeast Sphingolipid Phospholipase Gene ISC1 Regulates the Spindle Checkpoint by a CDC55 -Dependent Mechanism

Molecular and Cellular Biology(2020)10.1128/mcb.00340-19

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0DataRank · unranked

11 citations

Bachar H. Hassan, Jihui Ren, Ashraf A. Shamssedine, Eunmi Jeong, Baasil Shariff +10 more

Maternal and fetal alkaline ceramidase 2 is required for placental vascular integrity in mice

The FASEB Journal(2020)10.1096/fj.202001104r

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0DataRank · unranked

9 citations

Ruijuan Xu, Chih‐Li Lin, Benjamin E. Low, Louise Cai, Sally Li +8 more

Transcriptional Regulation of Sphingosine Kinase 1

Cells(2020)10.3390/cells9112437

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0DataRank · unranked

25 citations

Cungui Mao, Lina M. Obeid, Yusuf A. Hannun, Joseph Bonica

Neutral sphingomyelinase 2 regulates inflammatory responses in monocytes/macrophages induced by TNF-α

bioRxiv (Cold Spring Harbor Laboratory)(2020)10.1101/2020.05.06.080382

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0DataRank · unranked

1 citations

Zunair Ahmad, Reeby Thomas, Motasem Melhem, Ashley J. Snider, Lina M. Obeid +4 more

Asah2 Represses the p53–Hmox1 Axis to Protect Myeloid-Derived Suppressor Cells from Ferroptosis

The Journal of Immunology(2021)10.4049/jimmunol.2000500

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0DataRank · unranked

122 citations

John D. Klement, Chunwan Lu, Priscilla S. Redd, Dafeng Yang, Alyssa D. Smith +11 more

Ceramide kinase regulates TNF-α-induced immune responses in human monocytic cells

Scientific Reports(2021)10.1038/s41598-021-87795-7

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0DataRank · unranked

42 citations

Zunair Ahmad, Ashley J. Snider, Reeby Thomas, Shihab Kochumon, Motasem Melhem +6 more

Sublethal doxorubicin promotes migration and invasion of breast cancer cells: role of Src Family non-receptor tyrosine kinases

Breast Cancer Research(2021)10.1186/s13058-021-01452-5

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0DataRank · unranked

35 citations

A. Shamseddine, Benjamin Newcomb, Ronald S. Chavez, Tyler D. Panzner, Allen H. Lee +5 more

1-Deoxysphinganine initiates adaptive responses to serine and glycine starvation in cancer cells via proteolysis of sphingosine kinase

Journal of Lipid Research(2021)10.1016/j.jlr.2021.100154

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0DataRank · unranked

20 citations

Christian Ruiz, Emily Montal, Mónica Garcı́a-Barros, Izolda Mileva, Ashley J. Snider +4 more

Targeting sphingosine kinase 1 (SK1) enhances oncogene-induced senescence through ceramide synthase 2 (CerS2)-mediated generation of very-long-chain ceramides

Cell Death and Disease(2021)10.1038/s41419-020-03281-4

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0DataRank · unranked

17 citations

Christopher J. Clarke, Jeffrey L. Stith, Justin M. Snider, Naomi Newen, Christopher Gault +3 more

Group IIA Secreted Phospholipase A 2 Plays a Central Role in the Pathobiology of COVID-19

medRxiv(2021)10.1101/2021.02.22.21252237

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0DataRank · unranked

7 citations

Jeehyun Karen You, Xia Wang, Ashley J. Snider, Brian Hallmark, Michael C. Seeds +13 more

Synthesis of erythro- B13 enantiomers and stereospecific action of full set of B13-isomers in MCF7 breast carcinoma cells: Cellular metabolism and effects on sphingolipids

Bioorganic & Medicinal Chemistry(2021)10.1016/j.bmc.2021.116011

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0DataRank · unranked

0 citations

Jacek Bielawski, Alicja Bielawska, Yusuf A. Hannun, Aiping Bai

Ceramide Kinase Regulates TNF-α-induced Immune Responses in Human Monocytic Cells

Research Square(2021)10.21203/rs.3.rs-146950/v1

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0DataRank · unranked

0 citations

Zunair Ahmad, Ashley J. Snider, Reeby Thomas, Shihab Kochumon, Motasem Melhem +6 more

Molecular Cloning and Characterization of a Human Mitochondrial Ceramidase

UNC Libraries(2021)10.17615/mje0-2c34

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0DataRank · unranked

0 citations

Ting Qian, Yusuf A. Hannun, Alicja Bielawska, P. A. Roddy, Samer El Bawab +1 more

Neutral ceramidase deficiency protects against cisplatin-induced acute kidney injury

Journal of Lipid Research(2022)10.1016/j.jlr.2022.100179

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0DataRank · unranked

12 citations

Tess V. Dupre, Parag P. Shah, Deanna Davis, Mark A. Doll, Cierra N. Sharp +8 more

Targeting acid ceramidase ameliorates fibrosis in mouse models of non-alcoholic steatohepatitis

Frontiers in Medicine(2022)10.3389/fmed.2022.881848

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0DataRank · unranked

6 citations

Carson Cable, Sachin Sharma, Mahbubul H. Shihan, Aras N. Mattis, Izolda Mileva +4 more

Alkaline ceramidase catalyzes the hydrolysis of ceramides via a catalytic mechanism shared by Zn2+-dependent amidases

PLoS ONE(2022)10.1371/journal.pone.0271540

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0DataRank · unranked

3 citations

Ruijuan Xu, Lina M. Obeid, Yusuf A. Hannun, Michael V. Airola, Cungui Mao +1 more

The heat shock protein Hsp27 controls mitochondrial function by modulating ceramide generation

Cell Reports(2023)10.1016/j.celrep.2023.113081

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0DataRank · unranked

28 citations

Saurav Majumder, Johnny Stiban, Grace Mavodza, Alexandra J Straus, Sachin K. Kempelingaiah +5 more

ACSL1 is a key regulator of inflammatory and macrophage foaming induced by short-term palmitate exposure or acute high-fat feeding

iScience(2023)10.1016/j.isci.2023.107145

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0DataRank · unranked

27 citations

Dania Haddad, Ashraf Al Madhoun, Sardar Sindhu, Texy Jacob, Shihab Kochumon +5 more

Ceramide as an endothelial cell surface receptor and a lung-specific lipid vascular target for circulating ligands

Proceedings of the National Academy of Sciences(2023)10.1073/pnas.2220269120

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0DataRank · unranked

11 citations

Marina Cardó‐Vila, Jimmy A. Rotolo, Fernanda I. Staquicini, Fenny H. F. Tang, Tracey L. Smith +24 more

Biological function, topology, and quantification of plasma membrane Ceramide

Advances in Biological Regulation(2023)10.1016/j.jbior.2023.101009

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0DataRank · unranked

11 citations

Yusuf A. Hannun, Daniel Canals

Upregulation of sphingosine kinase 1 in response to doxorubicin generates an angiogenic response via stabilization of Snail

The FASEB Journal(2023)10.1096/fj.202201066r

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0DataRank · unranked

9 citations

Christopher J. Clarke, Lina M. Obeid, Chiara Luberto, Yusuf A. Hannun, Joseph Bonica

Neutral ceramidase-active site inhibitor chemotypes and binding modes

Bioorganic Chemistry(2023)10.1016/j.bioorg.2023.106747

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0DataRank · unranked

3 citations

John D. Bickel, Ronald J. Rahaim, Yuka Otsuka, Yong‐Mi Choi, Ruijuan Xu +14 more

A novel HSPB1S139F mouse model of Charcot-Marie-Tooth Disease

Prostaglandins & Other Lipid Mediators(2023)10.1016/j.prostaglandins.2023.106769

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0DataRank · unranked

1 citations

Kyra N. Hermanson, C. Beard, Nicholas Schwartz, Justin M. Snider, Benjamin E. Low +5 more

TGF-β and TNF-α interaction promotes the expression of MMP-9 through H3K36 dimethylation: implications in breast cancer metastasis

Frontiers in Immunology(2024)10.3389/fimmu.2024.1430187

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0DataRank · unranked

27 citations

Amnah Al-Sayyar, Texy Jacob, Fatemah Bahman, Nadeem Akhter, Ajit Wilson +5 more

A comprehensive measure of Golgi sphingolipid flux using NBD C6-ceramide: evaluation of sphingolipid inhibitors

Journal of Lipid Research(2024)10.1016/j.jlr.2024.100584

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0DataRank · unranked

7 citations

Justin M. Snider, Sitapriya Moorthi, Nicolas Coant, Magali Trayssac, Daniel Canals +4 more

Neutral Sphingomyelinase 2 Inhibition Limits Hepatic Steatosis and Inflammation

Cells(2024)10.3390/cells13050463

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0DataRank · unranked

5 citations

Hossein Arefanian, Ashraf Al Madhoun, Fatemah Bahman, Sardar Sindhu, Halemah AlSaeed +11 more

IL-6R (trans-signaling) is a key regulator of reverse cholesterol transport in lipid-laden macrophages

Clinical Immunology(2024)10.1016/j.clim.2024.110351

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0DataRank · unranked

4 citations

Halemah AlSaeed, Nourah Almansour, Fahd Al‐Mulla, Yusuf A. Hannun, Rasheed Ahmad +1 more

Orm proteins control ceramide synthesis and endocytosis via LCB-mediated Ypk1 regulation

Journal of Lipid Research(2024)10.1016/j.jlr.2024.100683

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0DataRank · unranked

4 citations

Robert Rieger, Nívea Pereira de Sá, Douglas Kelapire, Maurizio Del Poeta, Yusuf A. Hannun +1 more

The bioactive sphingolipid playbook. A primer for the uninitiated as well as sphingolipidologists

Journal of Lipid Research(2025)10.1016/j.jlr.2025.100813

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0DataRank · unranked

12 citations

Alfred H. Merrill, Chiara Luberto, Yusuf A. Hannun

Targeting ceramide synthases for the development of new antifungals

Structure(2025)10.1016/j.str.2025.05.016

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0DataRank · unranked

2 citations

Nívea Pereira de Sá, Kathryn Takemura, Kalani Jayanetti, Jeehyun Karen You, Niu De +9 more

Retention of lysosomal acid sphingomyelinase protects from Niemann-Pick Disease

Neurobiology of Disease(2025)10.1016/j.nbd.2025.107147

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0DataRank · unranked

1 citations

Kyra N. Hermanson, Justin M. Snider, Aki Hara, Brandon K Dahl, Janet Allopenna +9 more

Orm2 promotes nitrogen-induced sphingolipid production and endocytosis via Orm1 phosphorylation

Journal of Lipid Research(2025)10.1016/j.jlr.2025.100924

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0DataRank · unranked

0 citations

Yusuf A. Hannun, Jihui Ren

Targeting acid ceramidase inhibits YAP/TAZ signaling to reduce fibrosis in mice

Science Translational Medicine(2020)10.1126/scitranslmed.aay8798

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0DataRank · unranked

120 citations

Stephanie A. Christenson, Amy Yu, Nadia M.E. Ayad, Meghan Mooring, Joe M. Segal +28 more

A career in bioactive lipids

Journal of Biological Chemistry(2025)10.1016/j.jbc.2025.111041

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0DataRank · unranked

0 citations

Yusuf A. Hannun

Neutral sphingomyelinase 2 regulates inflammatory responses in monocytes/macrophages induced by TNF-α

Scientific Reports(2020)10.1038/s41598-020-73912-5

N/A

0DataRank · unranked

64 citations

Zunair Ahmad, Reeby Thomas, Motasem Melhem, Ashley J. Snider, Lina M. Obeid +4 more