Jianjun Chen

Also affiliated with City of Hope

Biochemistry, Genetics and Molecular BiologyMedicine

Pilot corpus only

This score is computed over theSindex pilot corpus and does not cover the full scientific literature. Scores are relative to papers we have ingested — papers, authors, and institutions outside the pilot are not represented. Methodology.

Top 100%percentile

0Author DataRank

Indexed papers

0in pilot corpus

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Papers

Driven by 60 papers. Top paper: “m6A Modification in Coding and Non-coding RNAs: Roles and Therapeutic Implications in Cancer”.

m6A Modification in Coding and Non-coding RNAs: Roles and Therapeutic Implications in Cancer

Cancer Cell(2020)10.1016/j.ccell.2020.02.004

N/A

12.9DataRank · unranked

1331 citations

Hengyou Weng, Jianjun Chen, Huilin Huang

Targeting FTO Suppresses Cancer Stem Cell Maintenance and Immune Evasion

Cancer Cell(2020)10.1016/j.ccell.2020.04.017

N/A

8.5DataRank · unranked

777 citations

Lei Dong, Yangchan Li, Min Gao, Li Han, Mark Wunderlich +34 more

FTO in cancer: functions, molecular mechanisms, and therapeutic implications

Trends in cancer(2022)10.1016/j.trecan.2022.02.010

N/A

5.3DataRank · unranked

250 citations

Rui Su, Xiaolan Deng, Yong Chen, Jianjun Chen, Yangchan Li

QKI shuttles internal m7G-modified transcripts into stress granules and modulates mRNA metabolism

Cell(2023)10.1016/j.cell.2023.05.047

N/A

4.0DataRank · unranked

187 citations

Ying Qing, Lei Dong, Li Han, Dong Wu, Yangchan Li +18 more

METTL16 drives leukemogenesis and leukemia stem cell self-renewal by reprogramming BCAA metabolism

Cell stem cell(2023)10.1016/j.stem.2022.12.006

N/A

3.0DataRank · unranked

158 citations

Lei Dong, Keith Leung, Zhicong Zhao, Yangchan Li, Lei Gao +24 more

TET2-mediated mRNA demethylation regulates leukemia stem cell homing and self-renewal

Cell stem cell(2023)10.1016/j.stem.2023.07.001

N/A

2.0DataRank · unranked

106 citations

Meilin Xue, Xiaolan Deng, Lei Dong, Le Xuan Truong Nguyen, Lili Ren +29 more

METTL16 promotes liver cancer stem cell self-renewal via controlling ribosome biogenesis and mRNA translation

Journal of Hematology & Oncology(2024)10.1186/s13045-024-01526-9

N/A

1.6DataRank · unranked

82 citations

Lei Dong, Honghai Zhang, Yangchan Li, Kangqiang Qiu, Zhicong Zhao +30 more

Lysine acetylation restricts mutant IDH2 activity to optimize transformation in AML cells

Molecular Cell(2021)10.1016/j.molcel.2021.06.027

N/A

1.0DataRank · unranked

24 citations

Siyuan Xia, Rukang Zhang, Yuancheng Li, Christopher Famulare, Hao Fan +20 more

RNA Demethylase ALKBH5 Selectively Promotes Tumorigenesis and Cancer Stem Cell Self-Renewal in Acute Myeloid Leukemia

Cell stem cell(2020)10.1016/j.stem.2020.04.009

N/A

0.895DataRank · unranked

388 citations

Yue Sheng, Allen Zhu, Sean Robinson, Xi Jiang, Lei Dong +19 more

miR-550-1 functions as a tumor suppressor in acute myeloid leukemia via the hippo signaling pathway

International Journal of Biological Sciences(2020)10.7150/ijbs.44365

N/A

0.839DataRank · unranked

19 citations

Mengxia Yu, Chenying Li, Yungui Wang, Xia Li, Bryan C. Ulrich +8 more

IFITM3 functions as a PIP3 scaffold to amplify PI3K signalling in B cells

Nature(2020)10.1038/s41586-020-2884-6

N/A

0.717DataRank · unranked

118 citations

Mark E. Robinson, Ning Ma, Dewan Artadji, Mohamed A. Ahmed, Gang Xiao +24 more

RBFOX2 recognizes N6-methyladenosine to suppress transcription and block myeloid leukaemia differentiation

Nature Cell Biology(2023)10.1038/s41556-023-01213-w

N/A

0.675DataRank · unranked

89 citations

Yu Xiao, Chao Shen, Kitty Wang, Tong Wu, Chang Liu +14 more

RNA N6-methyladenosine reader YTHDC1 is essential for TGF-beta-mediated metastasis of triple negative breast cancer

Theranostics(2022)10.7150/thno.71872

N/A

0.633DataRank · unranked

67 citations

Keren Zhou, Wei Liu, Emily Prince, Ying Qing, Yangchan Li +18 more

High-resolution characterization of gene function using single-cell CRISPR tiling screen

Nature Communications(2021)10.1038/s41467-021-24324-0

N/A

0.574DataRank · unranked

45 citations

Anthony Chan, Kazuya Miyashita, Christopher D. Delaney, Xi Wang, Hongzhi Li +21 more

Transplantation tolerance modifies donor-specific B cell fate to suppress de novo alloreactive B cells

Journal of Clinical Investigation(2020)10.1172/jci132814

N/A

0.489DataRank · unranked

25 citations

Dharmendra Jain, Jianjun Chen, Jinghui Yang, Dengping Yin, James S. Young +5 more

Cytoplasmic DROSHA and non-canonical mechanisms of MiR-155 biogenesis in FLT3-ITD acute myeloid leukemia

Leukemia(2021)10.1038/s41375-021-01166-9

N/A

0.434DataRank · unranked

17 citations

Bin Zhang, Dinh Hoa Hoang, Dandan Zhao, Huafeng Wang, Herman Wu +16 more

Ten-eleven translocation protein 1 modulates medulloblastoma progression

Genome biology(2021)10.1186/s13059-021-02352-9

N/A

0.418DataRank · unranked

9 citations

Yunhee Kang, Yujing Li, Li Chen, Li Lin, Nicholas D. Johnson +19 more

Metformin synergizes with gilteritinib in treating FLT3-mutated leukemia via targeting PLK1 signaling

Cell Reports Medicine(2024)10.1016/j.xcrm.2024.101645

N/A

0.396DataRank · unranked

13 citations

Chao Shen, Yi‐Ping Phoebe Chen, Zhenhua Chen, Keren Zhou, Yuanzhong Chen +17 more

8-Cl-Ado and 8-NH2-Ado synergize with venetoclax to target the methionine-MAT2A-SAM axis in acute myeloid leukemia

Leukemia(2024)10.1038/s41375-024-02222-w

N/A

0.330DataRank · unranked

8 citations

Ralf Buettner, Li Du, Zhenlong Li, Wei Liu, Rui Su +17 more

Signaling input from divergent pathways subverts malignant B-cell transformation

bioRxiv (Cold Spring Harbor Laboratory)(2020)10.1101/2020.03.12.989749

N/A

0.104DataRank · unranked

1 citations

Mark A. Murakami, Mark E. Robinson, Rebecca Caeser, Teresa Sadras, Jae Woong Lee +24 more

RNA-binding proteins in regulating mRNA stability and translation: roles and mechanisms in cancer

Seminars in Cancer Biology(2022)10.1016/j.semcancer.2022.03.025

N/A

0DataRank · unranked

168 citations

Xiaolan Deng, Jianjun Chen, Wei Li

A homozygous nonsense mutation in DNAJC30 causes Leber's hereditary optic neuropathy with Leigh-like phenotypes

Genes & Diseases(2022)10.1016/j.gendis.2022.09.011

N/A

0DataRank · unranked

2 citations

Kitty Wang, Wei Li, Álvaro Serrano, Kelly Powers, Chengwan Zhang +3 more

The roles and implications of RNA m6A modification in cancer

Nature Reviews Clinical Oncology(2023)10.1038/s41571-023-00774-x

N/A

0DataRank · unranked

343 citations

Ying Qing, David Horne, Huilin Huang, Jianjun Chen, Xiaolan Deng

YTHDF2 orchestrates tumor-associated macrophage reprogramming and controls antitumor immunity through CD8+ T cells

Nature Immunology(2023)10.1038/s41590-022-01398-6

N/A

0DataRank · unranked

221 citations

Baofa Sun, Songqi Duan, Jingjing Han, Tasha Barr, Jianying Zhang +7 more

Co-culture Systems of Drug-Treated Acute Myeloid Leukemia Cells and T Cells for In Vitro and In Vivo Study

STAR Protocols(2020)10.1016/j.xpro.2020.100097

N/A

0DataRank · unranked

6 citations

Rui Su, Jianjun Chen, Yangchan Li

RNA m6A reader YTHDF2 facilitates precursor miR-126 maturation to promote acute myeloid leukemia progression

Genes & Diseases(2023)10.1016/j.gendis.2023.01.016

N/A

0DataRank · unranked

37 citations

Keren Zhou, Han Li, Andrew Small, Jianhuang Xue, Huilin Huang +18 more

Epigenetic Control of Translation Checkpoint and Tumor Progression via RUVBL1‐EEF1A1 Axis

Advanced Science(2023)10.1002/advs.202206584

N/A

0DataRank · unranked

26 citations

Lu Yang, Anthony Chan, Sheela Pangeni Pokharel, Qiao Liu, Nicole Mattson +20 more

METTL3-Mediated m6A Modification Controls Splicing Factor Abundance and Contributes to Aggressive CLL

Blood Cancer Discovery(2023)10.1158/2643-3230.bcd-22-0156

N/A

0DataRank · unranked

28 citations

Meiling Jin, Mike M. Fernandez, Kevyn L. Hart, Aijun Liao, Xinzhou Ge +16 more

Phosphorylation stabilized TET1 acts as an oncoprotein and therapeutic target in B cell acute lymphoblastic leukemia

Science Translational Medicine(2023)10.1126/scitranslmed.abq8513

N/A

0DataRank · unranked

14 citations

Keren Zhou, Jianhuang Xue, Andrew Small, Gang Xiao, Le Xuan Truong Nguyen +35 more

Clinical Network Systems Biology: Traversing the Cancer Multiverse

Journal of Clinical Medicine(2023)10.3390/jcm12134535

N/A

0DataRank · unranked

12 citations

Jeremy Fricke, Stephen B. Gruber, Tingting Tan, Razmig Babikian, Pauline Kim +5 more

The roles and therapeutic implications of messenger RNA internal N7‐methylguanosine and N6‐methyladenosine modifications in chemoresistance

Clinical and Translational Medicine(2023)10.1002/ctm2.1400

N/A

0DataRank · unranked

2 citations

Ying Qing, Xiaolan Deng, Rui Su, Jianjun Chen, Zhicong Zhao

Dynamic phosphatase-recruitment controls B-cell selection and oncogenic signaling

bioRxiv (Cold Spring Harbor Laboratory)(2023)10.1101/2023.03.13.532151

N/A

0DataRank · unranked

4 citations

Mark E. Robinson, Ruifeng Sun, Kohei Kume, Ning Ma, Kadriye Nehir Cosgun +13 more

Targeted engagement of β-catenin-Ikaros complexes in refractory B-cell malignancies

bioRxiv (Cold Spring Harbor Laboratory)(2023)10.1101/2023.03.13.532152

N/A

0DataRank · unranked

1 citations

Huda Jumaa, Mark E. Robinson, Klaus M. Kistner, Liang Xu, Gang Xiao +18 more

Editorial: Novel insights in RNA modifications: From basic to translational research

Frontiers in Cell and Developmental Biology(2023)10.3389/fcell.2023.1155993

N/A

0DataRank · unranked

0 citations

Chengqi Yi, Pengxu Qian, Hengyou Weng, Jianjun Chen, Huilin Huang

Data from FTO-Dependent N6-Methyladenosine Modifications Inhibit Ovarian Cancer Stem Cell Self-Renewal by Blocking cAMP Signaling

(2023)10.1158/0008-5472.c.6512335

N/A

0DataRank · unranked

0 citations

Yinu Wang, Manoj Kandpal, Guangyuan Zhao, Horacio Cárdenas, Yanrong Ji +6 more

Targeting YTHDF2/MDSCs to improve radiotherapy

Cell chemical biology(2023)10.1016/j.chembiol.2023.06.024

N/A

0DataRank · unranked

0 citations

Ying Qing, Jianjun Chen, Xiaolan Deng

FTO-Dependent N 6 -Methyladenosine Modifications Inhibit Ovarian Cancer Stem Cell Self-Renewal by Blocking cAMP Signaling

Cancer Research(2020)10.1158/0008-5472.can-19-4044

N/A

0DataRank · unranked

249 citations

Yinu Wang, Manoj Kandpal, Guangyuan Zhao, Horacio Cárdenas, Yanrong Ji +6 more

YTHDF2 promotes ATP synthesis and immune evasion in B cell malignancies

Cell(2024)10.1016/j.cell.2024.11.007

N/A

0DataRank · unranked

69 citations

Chengwu Zeng, Lu Yang, Yuan Che, Meiling Chen, Lillian Sau +24 more

Targeting PRMT9-mediated arginine methylation suppresses cancer stem cell maintenance and elicits cGAS-mediated anticancer immunity

Nature Cancer(2024)10.1038/s43018-024-00736-x

N/A

0DataRank · unranked

30 citations

Xin He, Lei Zhang, Wei Chen, Yi‐Chun Lin, Songbai Liu +27 more

A novel class of inhibitors that disrupts the stability of integrin heterodimers identified by CRISPR-tiling-instructed genetic screens

Nature Structural & Molecular Biology(2024)10.1038/s41594-024-01211-y

N/A

0DataRank · unranked

21 citations

Anthony Chan, Kazuya Miyashita, Elizaveta Mukhaleva, Wenhan Chang, Lu Yang +22 more

IL1RAP-specific T cell engager depletes acute myeloid leukemia stem cells

Journal of Hematology & Oncology(2024)10.1186/s13045-024-01586-x

N/A

0DataRank · unranked

19 citations

Miso Park, Lucy Ghoda, Dandan Zhao, Melissa Valerio, Ebtesam Nafie +19 more

Non‐m6A RNA modifications in haematological malignancies

Clinical and Translational Medicine(2024)10.1002/ctm2.1666

N/A

0DataRank · unranked

8 citations

Yuanzhong Chen, Kitty Wang, Xiaolan Deng, Jianjun Chen, Meiling Chen

Genome-wide Association Studies in Ancestrally Diverse Populations: Opportunities, Methods, Pitfalls, and Recommendations

UNC Libraries(2024)10.17615/20e5-k172

N/A

0DataRank · unranked

0 citations

Evangelos Vassos, Bigdeli T.B, Sullivan P.F, Bryan Mowry, Lerato Majara +26 more

m6A/IGF2BP3-driven serine biosynthesis fuels AML stemness and metabolic vulnerability

Nature Communications(2025)10.1038/s41467-025-58966-1

N/A

0DataRank · unranked

17 citations

Yushuai Wang, Xiuxin Zhang, Weiwei Gao, Jingwen Li, Ying Yang +15 more

Epitranscriptomic control of cancer hallmarks: Functions, mechanisms, and therapeutics of RNA modifications

Cancer Cell(2025)10.1016/j.ccell.2025.12.001

N/A

0DataRank · unranked

13 citations

Dong Wu, Yingqi Zhao, Ying Qing, Huizhe Wu, Jianjun Chen +2 more

ALKBH1 Drives Tumorigenesis and Drug Resistance via tRNA-decoding Reprogramming and Codon-biased Translation

Cancer Discovery(2025)10.1158/2159-8290.cd-24-1043

N/A

0DataRank · unranked

8 citations

Yuan Che, Keren Zhou, Kitty Wang, Wei Li, D. S. Xue +28 more

DDX6 undergoes phase separation to modulate metabolic plasticity and chemoresistance

Nature Communications(2025)10.1038/s41467-025-66966-4

N/A

0DataRank · unranked

4 citations

Wei Li, Lili Ren, H. Zhang, Lei Dong, Anthony W.H. Chan +17 more

CRISPR screening reveals ZNF217 as a vulnerability in high-risk B-cell acute lymphoblastic leukemia

Theranostics(2025)10.7150/thno.100295

N/A

0DataRank · unranked

6 citations

Keren Zhou, Lei Dong, Yang Lü, Wei Li, Zhenhua Chen +15 more

Targeting RNA modification and mitochondrial metabolism cross talk in leukemic stem cells with CDK7 inhibitor TGN-1062

Blood Advances(2025)10.1182/bloodadvances.2024014225

N/A

0DataRank · unranked

0 citations

Leying Zhang, Mohan R. Kaadige, Melissa Valerio, Dinh Hoa Hoang, Trason Thode +17 more

R-2-hydroxyglutarate attenuates aerobic glycolysis in leukemia by targeting the FTO/m6A/PFKP/LDHB axis

Molecular Cell(2021)10.1016/j.molcel.2020.12.026

N/A

0DataRank · unranked

354 citations

Lei Dong, Lei Gao, Chenying Li, Yangchan Li, Li Han +24 more

N6-methyladenosine regulation of mRNA translation is essential for early human erythropoiesis

bioRxiv (Cold Spring Harbor Laboratory)(2025)10.1101/2025.11.10.687731

N/A

0DataRank · unranked

0 citations

Sonali Arora, Cindy L. Wladyka, Ryan A. Flynn, Shun Liu, Yong Peng +7 more

The RNA m6A reader YTHDF2 controls NK cell antitumor and antiviral immunity

The Journal of Experimental Medicine(2021)10.1084/jem.20210279

N/A

0DataRank · unranked

208 citations

Jiazhuo Yan, Tasha Barr, Jianying Zhang, Zhenhua Chen, Li‐Shu Wang +5 more

N(6)-methyladenosine-binding protein YTHDF1 suppresses EBV replication and promotes EBV RNA decay

EMBO Reports(2021)10.15252/embr.202050128

N/A

0DataRank · unranked

107 citations

Xingyang Li, Xueping Wang, Yunjia Zhu, Hua Zhang, Weisheng Cheng +23 more

RNA modifications in hematopoietic malignancies: a new research frontier

Blood(2021)10.1182/blood.2019004263

N/A

0DataRank · unranked

57 citations

Rui Su, Jianjun Chen, Ying Qing

Targeting differentiation blockade in AML: New hope from cell-surface-based CRISPR screens

Cell stem cell(2021)10.1016/j.stem.2021.03.006

N/A

0DataRank · unranked

7 citations

Ying Qing, Jianjun Chen, Rui Su

Evaluation of glycolytic rates in human hematopoietic stem/progenitor cells after target gene depletion

STAR Protocols(2021)10.1016/j.xpro.2021.100603

N/A

0DataRank · unranked

5 citations

Lei Gao, Li Han, Rui Su, Jianjun Chen, Ying Qing

The RNA m 6 A reader YTHDF2 controls NK cell anti-tumor and anti-viral immunity

bioRxiv (Cold Spring Harbor Laboratory)(2021)10.1101/2021.04.26.441557

N/A

0DataRank · unranked

2 citations

Jiazhuo Yan, Tasha Barr, Jianying Zhang, Zhenhua Chen, Li‐Shu Wang +5 more

High-resolution characterization of gene function using single-cell CRISPR tiling screen

Research Square(2021)10.21203/rs.3.rs-135816/v1

N/A

0DataRank · unranked

1 citations

Anthony Chan, Kazuya Miyashita, Christopher D. Delaney, Xi Wang, Hongzhi Li +21 more

The m6A reader IGF2BP2 regulates glutamine metabolism and represents a therapeutic target in acute myeloid leukemia

Cancer Cell(2022)10.1016/j.ccell.2022.10.004

N/A

0DataRank · unranked

319 citations

Feng Huang, Zhaojin Yu, Zhenhua Chen, Emily Prince, Yalin Kang +29 more

RNA N6-methyladenosine modification in solid tumors: new therapeutic frontiers

Cancer Gene Therapy(2020)10.1038/s41417-020-0160-4

N/A

0DataRank · unranked

32 citations

Jianjun Chen, Laleh G. Melstrom