John Sembrat

Also affiliated with Pulmonary and Allergy Associates

Medicine

Pilot corpus only

This score is computed over theSindex pilot corpus and does not cover the full scientific literature. Scores are relative to papers we have ingested — papers, authors, and institutions outside the pilot are not represented. Methodology.

Top 4%percentile

0.827Author DataRank

Indexed papers

1in pilot corpus

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Why this DataRank?

An author's DataRank is the sum of the DataRanks of all 1 indexed paper attributed to them. A prolific author with many moderate-impact papers can outrank one with a single high-impact paper.

Author scores recompute whenever paper DataRanks are refreshed, so this number lags the underlying paper scores by at most one batch run.

Read the full methodology →

The highest-impact dataset this researcher has shared, ranked by DataRank — the single contribution doing the most to lift their data-sharing standing.

Topographic heterogeneity of lung microbiota in end-stage idiopathic pulmonary fibrosis: the Microbiome in Lung Explants-2 (MiLEs-2) study

Thorax(2020)10.1136/thoraxjnl-2020-214770

Top 24%

0.827DataRank

Top 24%23 citations

Haopu Yang, John Sembrat, Libing Yang, Spencer Winters, Rachel Nettles +13 more

Papers

Driven by 38 papers — median percentile 76. Top paper: “Apoptosis of hematopoietic progenitor-derived adipose tissue–resident macrophages contributes to insulin resistance after myocardial infarction”.

Apoptosis of hematopoietic progenitor-derived adipose tissue–resident macrophages contributes to insulin resistance after myocardial infarction

Science Translational Medicine(2020)10.1126/scitranslmed.aaw0638

N/A

0.982DataRank · unranked

24 citations

Emilie Coppin, Xinyi Zhang, Jonathan Florentin, Sasha Koul, Matthias Götberg +11 more

Topographic heterogeneity of lung microbiota in end-stage idiopathic pulmonary fibrosis: the Microbiome in Lung Explants-2 (MiLEs-2) study

Thorax(2020)10.1136/thoraxjnl-2020-214770

Top 24%

0.827DataRank

Top 24%23 citations

Haopu Yang, John Sembrat, Libing Yang, Spencer Winters, Rachel Nettles +13 more

Ewing Sarcoma and Osteosarcoma Have Distinct Immune Signatures and Intercellular Communication Networks

Clinical Cancer Research(2022)10.1158/1078-0432.ccr-22-1471

N/A

0.678DataRank · unranked

91 citations

Elina Mukherjee, Nathanael G. Bailey, Sayali Onkar, Jessica D. Daley, Cláudia Salgado +11 more

Interleukin-6 mediates neutrophil mobilization from bone marrow in pulmonary hypertension

Cellular and Molecular Immunology(2021)10.1038/s41423-020-00608-1

N/A

0.675DataRank · unranked

89 citations

Jingsi Zhao, Yi‐Yin Tai, Sathish Babu Vasamsetti, Scott O'Neil, Rahul Kumar +11 more

Frataxin deficiency promotes endothelial senescence in pulmonary hypertension

Journal of Clinical Investigation(2021)10.1172/jci136459

N/A

0.654DataRank · unranked

77 citations

Jingsi Zhao, Yi‐Yin Tai, Ying Tang, Dror Perk, Vinny Negi +26 more

Airway-derived emphysema-specific alveolar type II cells exhibit impaired regenerative potential in COPD

European Respiratory Journal(2024)10.1183/13993003.02071-2023

N/A

0.510DataRank · unranked

29 citations

Qianjiang Hu, Meshal Ansari, Kent Riemondy, Ricardo Pineda, John Sembrat +14 more

Molecular Changes Implicate Angiogenesis and Arterial Remodeling in Systemic Sclerosis–Associated and Idiopathic Pulmonary Hypertension

Arteriosclerosis Thrombosis and Vascular Biology(2024)10.1161/atvbaha.123.320005

N/A

0.489DataRank · unranked

25 citations

Tracy Tabib, Mengqi Huang, Ke Yuan, Yunhye Kim, Christina Morse +4 more

Increased expression of CXCL6 in secretory cells drives fibroblast collagen synthesis and is associated with increased mortality in idiopathic pulmonary fibrosis

European Respiratory Journal(2023)10.1183/13993003.00088-2023

N/A

0.464DataRank · unranked

21 citations

Jiangning Tan, Rosa Marie Apel, Benjamin Seeliger, Jonas C. Schupp, Xiaoyun Li +24 more

A deep generative model for deciphering cellular dynamics and in silico drug discovery in complex diseases

Nature Biomedical Engineering(2025)10.1038/s41551-025-01423-7

N/A

0.457DataRank · unranked

20 citations

Jonas C. Schupp, Taylor Adams, Gérémy Clair, A. Justet, Farida Ahangari +17 more

SCUBE1 Controls BMPR2-Relevant Pulmonary Endothelial Function

JACC Basic to Translational Science(2020)10.1016/j.jacbts.2020.08.010

N/A

0.373DataRank · unranked

11 citations

Ying Tang, Yi‐Yin Tai, Adam Handen, Jingsi Zhao, Gil Speyer +24 more

Cigarette smoking is a secondary cause of folliculin loss

Thorax(2022)10.1136/thoraxjnl-2021-217197

N/A

0.330DataRank · unranked

8 citations

Yandong Lai, Zachary Lane, H. Strollo, Kazuya Tanimura, John Sembrat +7 more

Altered AP-1, RUNX and EGR chromatin dynamics drive fibrotic lung disease

bioRxiv (Cold Spring Harbor Laboratory)(2024)10.1101/2024.10.23.619858

N/A

0.312DataRank · unranked

7 citations

Minxue Jia, Peter Gerges, Jing‐Yu Fan, Tracy Tabib, Rithika Behara +7 more

VX-445 (elexacaftor) inhibits chloride secretion across human bronchial epithelial cells by directly blocking KCa3.1 channels

PNAS Nexus(2025)10.1093/pnasnexus/pgaf211

N/A

0.269DataRank · unranked

5 citations

Corina Balut, M. Green, John Sembrat, Robert J. Bridges, Ashvani K Singh +4 more

Redox regulation of lung endothelial PERK, unfolded protein response (UPR) and proliferation via NOX1: Targeted inhibition as a potential therapy for PAH

Redox Biology(2025)10.1016/j.redox.2025.103554

N/A

0.255DataRank · unranked

4 citations

Alex Kufner, Christopher M. Dustin, Imad Al Ghouleh, Shuai Yuan, Adam C. Straub +6 more

Data from Ewing Sarcoma and Osteosarcoma Have Distinct Immune Signatures and Intercellular Communication Networks

(2023)10.1158/1078-0432.c.6532980.v1

N/A

0DataRank · unranked

0 citations

Elina Mukherjee, Nathanael G. Bailey, Sayali Onkar, Jessica D. Daley, Cláudia Salgado +11 more

Potentiation of BKCa channels by cystic fibrosis transmembrane conductance regulator correctors VX-445 and VX-121

Journal of Clinical Investigation(2024)10.1172/jci176328

N/A

0DataRank · unranked

11 citations

Stefanie Taiclet, Michael M. Myerburg, John Sembrat, Robert J. Bridges, Adam C. Straub +4 more

Cardiac matrix-bound Nanovesicles provide insight into mechanisms of clinical heart disease progression to failure

International Journal of Cardiology(2024)10.1016/j.ijcard.2024.132892

N/A

0DataRank · unranked

4 citations

Matt Borrelli, Lisa Mathews, Marley J. Dewey, William E. Schwarzmann, Vishal Soman +8 more

Differential bioenergetics in adult rodent cardiomyocytes isolated from the right versus left ventricle

Journal of Molecular and Cellular Cardiology(2024)10.1016/j.yjmcc.2024.04.003

N/A

0DataRank · unranked

7 citations

Krithika Rao, John Sembrat, Claudette M. St. Croix, Brett A. Kaufman, Iain Scott +3 more

IL-10 Is Critical for Regulation of Cytotoxic CD4+NKG7+ T Cells in Lung Allograft Rejection but Is Not Required for Allograft Acceptance

The Journal of Immunology(2024)10.4049/jimmunol.2400279

N/A

0DataRank · unranked

0 citations

Xingan Wang, Kaitlyn Devonshire, Emily Lyons, Iulia Popescu, Zihe Zhou +9 more

NKG2D blockade impairs tissue-resident memory T cell accumulation and reduces chronic lung allograft dysfunction

JCI Insight(2025)10.1172/jci.insight.184048

N/A

0DataRank · unranked

13 citations

Madeline A. Lipp, Marta Bueno, Andrew Craig, Michelle Rojas, Mohammed Abbas +14 more

Endothelial ADAR1 Deficit Induces the NOCT-IRF7 Axis in Pulmonary Hypertension

Circulation Research(2025)10.1161/circresaha.125.326277

N/A

0DataRank · unranked

7 citations

Giovanni Maroli, Hyunbum Kim, Yi‐Yin Tai, Ying Tang, Satoshi Okawa +23 more

Targeting cannabinoid receptor 1 for antagonism in pro-fibrotic alveolar macrophages mitigates pulmonary fibrosis

JCI Insight(2025)10.1172/jci.insight.187967

N/A

0DataRank · unranked

3 citations

Muhammad Arif, Kaelin M. Wolf, Madeline Behee, Natalie L. Johnson, Lenny Pommerolle +14 more

(R)-vanzacaftor potentiates BKCa channels in the absence of CFTR correction or potentiation

American Journal of Physiology-Cell Physiology(2025)10.1152/ajpcell.00654.2025

N/A

0DataRank · unranked

3 citations

Scott Hahn, John Sembrat, Adam C. Straub, Michael Butterworth, Daniel C. Devor +1 more

Transcriptional profiling of lung cell populations in idiopathic pulmonary arterial hypertension

Pulmonary Circulation(2020)10.1177/2045894020908782

N/A

0DataRank · unranked

121 citations

Tracy Tabib, Humberto E. Trejo Bittar, Eleanor Valenzi, John Sembrat, Stephen Y. Chan +3 more

Altered AP-1, RUNX, and EGR chromatin dynamics drive human fibrotic lung disease

Annals of the Rheumatic Diseases(2025)10.1016/j.ard.2025.12.003

N/A

0DataRank · unranked

2 citations

Minxue Jia, Peter Gerges, Jingyu Fan, Tracy Tabib, Rithika Behera +10 more

Cigarette smoke exposure enhances transforming acidic coiled-coil–containing protein 2 turnover and thereby promotes emphysema

JCI Insight(2020)10.1172/jci.insight.125895

N/A

0DataRank · unranked

18 citations

Xiuying Li, Jun-Ho Jang, Tomasz W. Kamiński, Aki Hoji, Tiffany A. Coon +13 more

Topographic Heterogeneity of Lung Microbiota in End-Stage Idiopathic Pulmonary Fibrosis: The Microbiome in Lung Explants-2 (MiLEs-2) Study

medRxiv(2020)10.1101/2020.03.05.20031021

N/A

0DataRank · unranked

0 citations

Haopu Yang, John Sembrat, Libing Yang, Spencer Winters, Rachel Nettles +13 more

Computational repurposing of therapeutic small molecules from cancer to pulmonary hypertension

Science Advances(2021)10.1126/sciadv.abh3794

N/A

0DataRank · unranked

39 citations

Jimin Yang, Gil Speyer, Andrés Pulgarin, Adam Handen, Jingsi Zhao +26 more

Human ex vivo lung perfusion: a novel model to study human lung diseases

Scientific Reports(2021)10.1038/s41598-020-79434-4

N/A

0DataRank · unranked

30 citations

John Sembrat, Kentaro Noda, Tyler Lovelace, Diana Álvarez, Humberto E. Trejo Bittar +6 more

High CXCL6 drives matrix expression and correlate with markers of poor outcome in IPF

bioRxiv (Cold Spring Harbor Laboratory)(2021)10.1101/2021.06.22.449424

N/A

0DataRank · unranked

1 citations

Jiangning Tan, Rosa Marie Apel, Benjamin Seeliger, Xiaoyun Li, Ting‐Yun Chen +19 more

GPER-dependent estrogen signaling increases cardiac GCN5L1 expression and MCAD activity

bioRxiv (Cold Spring Harbor Laboratory)(2021)10.1101/2021.09.20.461099

N/A

0DataRank · unranked

0 citations

Dharendra Thapa, Manling Zhang, Michael W. Stoner, John Sembrat, Mauricio Rojas +2 more

Loss of Amphiregulin drives inflammation and endothelial apoptosis in pulmonary hypertension

Life Science Alliance(2022)10.26508/lsa.202101264

N/A

0DataRank · unranked

37 citations

Jingsi Zhao, Yi‐Yin Tai, Wei Sun, Lee L Ohayon, Scott O'Neil +10 more

Cross-Regulation of F-Box Protein FBXL2 with T-bet and TNF-α during Acute and Chronic Lung Allograft Rejection

The Journal of Immunology(2022)10.4049/jimmunol.2200245

N/A

0DataRank · unranked

3 citations

Xingan Wang, Jianxin Wei, Aki Hoji, Tiffany A. Coon, Iulia Popescu +16 more

The Role of EBP50 in Regulating Endothelial-To-Mesenchymal Transition in Pulmonary Hypertension

bioRxiv (Cold Spring Harbor Laboratory)(2022)10.1101/2022.05.31.494181

N/A

0DataRank · unranked

0 citations

Mariah Berman, Maryam Sharifi‐Sanjani, Andrés Pulgarin, Anas Alsuraimi, Patricia Riva +23 more

Single-nucleus chromatin accessibility identifies a critical role for TWIST1 in idiopathic pulmonary fibrosis myofibroblast activity

European Respiratory Journal(2023)10.1183/13993003.00474-2022

N/A

0DataRank · unranked

31 citations

Harinath Bahudhanapati, Jiangning Tan, Tracy Tabib, Daniel I. Sullivan, Mehdi Nouraie +11 more

Impact of enzymatic digestion on single cell suspension yield from peripheral human lung tissue

Cytometry Part A(2023)10.1002/cyto.a.24777

N/A

0DataRank · unranked

15 citations

Andrew Craig, Li Fan, Eleanor Valenzi, William Bain, Robert Lafyatis +4 more

CYB5R3 in type II alveolar epithelial cells protects against lung fibrosis by suppressing TGF-β1 signaling

JCI Insight(2023)10.1172/jci.insight.161487

N/A

0DataRank · unranked

13 citations

Jazmín Calyeca, Timur O. Khaliullin, Megan Miller, Diana Álvarez, Lorena Rosas +17 more

Data from Ewing Sarcoma and Osteosarcoma Have Distinct Immune Signatures and Intercellular Communication Networks

(2023)10.1158/1078-0432.c.6532980

N/A

0DataRank · unranked

0 citations

Elina Mukherjee, Nathanael G. Bailey, Sayali Onkar, Jessica D. Daley, Cláudia Salgado +11 more

John Sembrat

Indexed papers

Top data-sharing exemplar

Papers