Sridhar Mani

MedicinePharmacology, Toxicology and PharmaceuticsBiochemistry, Genetics and Molecular Biology

Pilot corpus only

This score is computed over theSindex pilot corpus and does not cover the full scientific literature. Scores are relative to papers we have ingested — papers, authors, and institutions outside the pilot are not represented. Methodology.

Top 100%percentile

0Author DataRank

Indexed papers

0in pilot corpus

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Papers

Driven by 29 papers. Top paper: “Activation of PXR by Alpinetin Contributes to Abrogate Chemically Induced Inflammatory Bowel Disease”.

Activation of PXR by Alpinetin Contributes to Abrogate Chemically Induced Inflammatory Bowel Disease

Frontiers in Pharmacology(2020)10.3389/fphar.2020.00474

N/A

1.1DataRank · unranked

30 citations

Bei Yue, Lili Ding, Xiaoping Luo, Yijing Ren, Jingjing Zhang +4 more

Targeting the pregnane X receptor using microbial metabolite mimicry

EMBO Molecular Medicine(2020)10.15252/emmm.201911621

N/A

0.663DataRank · unranked

82 citations

Felix Kopp, Cait M. Costello, Jazmin S. Kemp, Hao Li, Aneta Vrzalová +37 more

Acacetin Ameliorates Experimental Colitis in Mice via Inhibiting Macrophage Inflammatory Response and Regulating the Composition of Gut Microbiota

Frontiers in Physiology(2021)10.3389/fphys.2020.577237

N/A

0.654DataRank · unranked

77 citations

Bei Yue, Hao Wang, Beibei Zhang, Xiaoping Luo, Zhilun Yu +6 more

An abundant ginger compound furanodienone alleviates gut inflammation via the xenobiotic nuclear receptor PXR in mice

Nature Communications(2025)10.1038/s41467-025-56624-0

N/A

0.416DataRank · unranked

15 citations

Guohui Zhang, Zhiwei Bian, Vimanda Chow, Marina Grimaldi, Coralie Carivenc +23 more

Garcinoic acid prevents β-amyloid (Aβ) deposition in the mouse brain

Journal of Biological Chemistry(2020)10.1074/jbc.ra120.013303

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0DataRank · unranked

35 citations

Pierangelo Torquato, Desirée Bartolini, Cristina Mas‐Bargues, Guido Bellezza, Antimo Gioiello +13 more

Early Life Exposure to Environmental Contaminants (BDE-47, TBBPA, and BPS) Produced Persistent Alterations in Fecal Microbiome in Adult Male Mice

Toxicological Sciences(2020)10.1093/toxsci/kfaa161

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0DataRank · unranked

40 citations

Moumita Dutta, Alexander Suvorov, Xiaojian Shi, Haiwei Gu, Sridhar Mani +2 more

Obacunone reduces inflammatory signalling and tumour occurrence in mice with chronic inflammation-induced colorectal cancer

Pharmaceutical Biology(2020)10.1080/13880209.2020.1812673

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0DataRank · unranked

26 citations

Zhilun Yu, Bei Yue, Junyu Ren, Jing Zhang, Sridhar Mani +3 more

Novel Yeast-based Strategy Unveils Antagonist Binding Regions on the Nuclear Xenobiotic Receptor PXR

UNC Libraries(2020)10.17615/60re-nn90

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0DataRank · unranked

1 citations

Nicolin Bloch, Sridhar Mani, Ganjam V. Kalpana, Abdissa Negassa, Matthew R. Redinbo +5 more

Understanding the Physiological Functions of the Host Xenobiotic-sensing Nuclear Receptors PXR and CAR on the Gut Microbiome using Genetically Modified Mice

(2020)10.21203/rs.3.rs-36593/v1

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0DataRank · unranked

3 citations

Moumita Dutta, Hao Li, Adam Matson, Xiaojian Shi, Haiwei Gu +3 more

Dietary Monoterpenoids As a New Class of Allosteric Human Aryl Hydrocarbon Receptor Antagonists

bioRxiv (Cold Spring Harbor Laboratory)(2020)10.1101/2020.11.30.404178

N/A

0DataRank · unranked

0 citations

Iveta Zůvalová, Barbora Vyhlídalová, Kristýna Krasulová, Eva Jiskrová, Radim Vrzal +9 more

Structure and Inhibition of Microbiome β-Glucuronidases Essential to the Alleviation of Cancer Drug Toxicity

UNC Libraries(2020)10.17615/rmmr-1373

N/A

0DataRank · unranked

0 citations

Matthew R. Redinbo, Esteban G. Figueroa, James D. Ingle, Rebecca M. Pollet, Madhu Kumar Venkatesh +16 more

PXR antagonists and implication in drug metabolism

UNC Libraries(2020)10.17615/ahmm-xx59

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0DataRank · unranked

0 citations

Sridhar Mani, Wei Dou, Matthew R. Redinbo

Symbiotic Bacterial Metabolites Regulate Gastrointestinal Barrier Function via the Xenobiotic Sensor PXR and Toll-like Receptor 4

Carolina Digital Repository (University of North Carolina at Chapel Hill)(2020)10.17615/a268-h719

N/A

0DataRank · unranked

0 citations

Subhajit Mukherjee, Hongwei Wang, Zhijuan Qiu, Sridhar Mani, Katherine Sun +14 more

Elucidating the ‘Jekyll and Hyde’ Nature of PXR: The Case for Discovering Antagonists or Allosteric Antagonists

UNC Libraries(2020)10.17615/9gpw-fq51

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0DataRank · unranked

0 citations

Matthew R. Redinbo, Hao Li, Matthew D. Krasowski, Sean Ekins, Sridhar Mani +1 more

Bacterial Swarmers Enriched During Intestinal Stress Ameliorate Damage

Gastroenterology(2021)10.1053/j.gastro.2021.03.017

N/A

0DataRank · unranked

34 citations

Weijie Chen, Hao Li, Justin Wright, Regina Lamendella, Dana J. Lukin +17 more

Confinement discerns swarmers from planktonic bacteria

eLife(2021)10.7554/elife.64176

N/A

0DataRank · unranked

27 citations

Neha Mani, Hamid Karani, Hao Li, Sridhar Mani, Jay X. Tang +1 more

Neonatal Exposure to BPA, BDE-99, and PCB Produces Persistent Changes in Hepatic Transcriptome Associated With Gut Dysbiosis in Adult Mouse Livers

Toxicological Sciences(2021)10.1093/toxsci/kfab104

N/A

0DataRank · unranked

23 citations

Moumita Dutta, Joseph L. Dempsey, Hans‐Joachim Lehmler, James W. MacDonald, Theo K. Bammler +6 more

An expanding bacterial colony forms a depletion zone with growing droplets

Soft Matter(2021)10.1039/d0sm01348j

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0DataRank · unranked

13 citations

Jordan Bell, Weijie Chen, Sridhar Mani, Jay X. Tang, Hui Ma

Deciphering structural bases of intestinal and hepatic selectivity in targeting pregnane X receptor with indole-based microbial mimics

Bioorganic Chemistry(2021)10.1016/j.bioorg.2021.104661

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0DataRank · unranked

17 citations

Peter Illéš, Chamini V. Karunaratne, Lars Ulrik Nordstrøm, Xiaoping Luo, Annie Yang +17 more

Enterobacter sp. Strain SM1_HS2B Manifests Transient Elongation and Swimming Motility in Liquid Medium

Microbiology Spectrum(2022)10.1128/spectrum.02078-21

N/A

0DataRank · unranked

4 citations

Haoming Liu, Hamid Karani, Jon Mallen, Weijie Chen, Arpan De +3 more

Maternal PBDE exposure disrupts gut microbiome and promotes hepatic proinflammatory signaling in humanized PXR-transgenic mouse offspring over time

Toxicological Sciences(2023)10.1093/toxsci/kfad056

N/A

0DataRank · unranked

21 citations

Hao Li, Yan Jin, Jasmine Armad, Haiwei Gu, Sridhar Mani +2 more

Diindoles produced from commensal microbiota metabolites function as endogenous CAR/Nr1i3 ligands

Nature Communications(2024)10.1038/s41467-024-46559-3

N/A

0DataRank · unranked

18 citations

Ainaz Malekoltojari, Anjana Asokakumar, Vimanda Chow, Linhao Li, Hao Li +14 more

Outcomes Among Racial and Ethnic Minority Patients With Advanced Cancers in Phase 1 Trials

JAMA Network Open(2024)10.1001/jamanetworkopen.2024.21485

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0DataRank · unranked

4 citations

Abdissa Negassa, Mohammad H. Ghalib, Imran Chaudhary, Kavita Desai, Umang Shah +5 more

Unlocking the potential: FKK6 as a microbial mimicry-based therapy for chronic inflammation-associated colorectal cancer in a murine model

Journal of Pharmacology and Experimental Therapeutics(2024)10.1016/j.jpet.2024.100059

N/A

0DataRank · unranked

3 citations

Hao Li, Vera DesMarais, Amanda P. Beck, Hillary Guzik, Barbora Vyhlídalová +4 more

Gut Microbial Catabolites of Tryptophan Are Ligands and Agonists of the Aryl Hydrocarbon Receptor: A Detailed Characterization

International Journal of Molecular Sciences(2020)10.3390/ijms21072614

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0DataRank · unranked

154 citations

Kristýna Krasulová, Petra Pečinková, Adéla Marcalíková, Radim Vrzal, Lenka Zemánková +7 more

Cytoplasmic PXR regulates glucose metabolism by binding mRNAs and modulating their stability

Nature Structural & Molecular Biology(2025)10.1038/s41594-025-01614-5

N/A

0DataRank · unranked

3 citations

Zehua Wang, Sihan Li, Dhamotharan Pattarayan, Yifei Wang, Jingchen Zhai +11 more

Tryptophan Metabolism as a Pharmacological Target

Trends in Pharmacological Sciences(2020)10.1016/j.tips.2020.11.006

N/A

0DataRank · unranked

286 citations

Nathalie Rolhion, Sridhar Mani, Harry Sokol, Morgane Modoux

Drug Mimicry: Promiscuous Receptors PXR and AhR, and Microbial Metabolite Interactions in the Intestine

Trends in Pharmacological Sciences(2020)10.1016/j.tips.2020.09.013

N/A

0DataRank · unranked

65 citations

Harry Sokol, Sridhar Mani, Zdeněk Dvořák

Garcinoic Acid Is a Natural and Selective Agonist of Pregnane X Receptor

Journal of Medicinal Chemistry(2020)10.1021/acs.jmedchem.0c00012

N/A

0DataRank · unranked

47 citations

Francesca Franco, Pierangelo Torquato, Rita Marinelli, Bruno Cerra, Riccardo Ronchetti +14 more