Marco Ruella

Hospital of the University of Pennsylvania

Also affiliated with Parker Institute for Cancer Immunotherapy, University of Pennsylvania

Medicine

Pilot corpus only

This score is computed over theSindex pilot corpus and does not cover the full scientific literature. Scores are relative to papers we have ingested — papers, authors, and institutions outside the pilot are not represented. Methodology.

Top 100%percentile

0Author DataRank

Indexed papers

2in pilot corpus

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Why this DataRank?

An author's DataRank is the sum of the DataRanks of all 2 indexed papers attributed to them. A prolific author with many moderate-impact papers can outrank one with a single high-impact paper.

Author scores recompute whenever paper DataRanks are refreshed, so this number lags the underlying paper scores by at most one batch run.

Read the full methodology →

Papers

Driven by 27 papers. Top paper: “Modulation of CD22 Protein Expression in Childhood Leukemia by Pervasive Splicing Aberrations: Implications for CD22-Directed Immunotherapies”.

Modulation of CD22 Protein Expression in Childhood Leukemia by Pervasive Splicing Aberrations: Implications for CD22-Directed Immunotherapies

Blood Cancer Discovery(2021)10.1158/2643-3230.bcd-21-0087

N/A

2.2DataRank · unranked

63 citations

Elisabeth Gillespie, Ammar S. Naqvi, Katharina E. Hayer, Zhiwei Ang, Manuel Torres-Diz +17 more

Antigen glycosylation regulates efficacy of CAR T cells targeting CD19

Nature Communications(2022)10.1038/s41467-022-31035-7

N/A

1.6DataRank · unranked

69 citations

Jack H. Landmann, Ava R. Hansen, Alkmini Papadopolou, Yu-Sung Hsu, Mehmet Emrah Selli +14 more

An NK-like CAR T cell transition in CAR T cell dysfunction

Cell(2021)10.1016/j.cell.2021.11.016

N/A

0.902DataRank · unranked

409 citations

M. Ángela Aznar, Shunichiro Kuramitsu, Parisa Samareh, Sangya Agarwal, Greg Donahue +25 more

Pembrolizumab for B-cell lymphomas relapsing after or refractory to CD19-directed CAR T-cell therapy

Blood(2022)10.1182/blood.2021012634

N/A

0.792DataRank · unranked

196 citations

Cécile Alanio, Jakub Svoboda, Sunita D. Nasta, Daniel J. Landsburg, Simon F. Lacey +5 more

CD22-targeted chimeric antigen receptor-modified T cells for children and adults with relapse of B-cell acute lymphoblastic leukemia after CD19-directed immunotherapy

Journal for ImmunoTherapy of Cancer(2025)10.1136/jitc-2025-011549

N/A

0.628DataRank · unranked

21 citations

Amanda M DiNofia, Yimei Li, Caroline Diorio, Hongyan Liu, Gerald Wertheim +24 more

Alternative splicing of its 5′-UTR limits CD20 mRNA translation and enables resistance to CD20-directed immunotherapies

Blood(2023)10.1182/blood.2023020400

N/A

0.581DataRank · unranked

47 citations

Luca Paruzzo, Katharina E. Hayer, Carolin Schmidt, Manuel Torres-Diz, Feng Xu +19 more

Immunologic Predictors of Vaccine Responsiveness in Patients With Lymphoma and Chronic Lymphocytic Leukemia

The Journal of Infectious Diseases(2024)10.1093/infdis/jiae106

N/A

0.389DataRank · unranked

7 citations

Kingsley Gideon Kumashie, Emeline R. Chong, Joseph Fabrizio, Aditi Gupta, Jakub Svoboda +38 more

Manufacturing of CRISPR-edited primary mouse CAR T cells for cancer immunotherapy

Nature Protocols(2025)10.1038/s41596-025-01208-x

N/A

0.292DataRank · unranked

6 citations

Ranjani Ramasubramanian, Siena Nason, Alberto Carturan, Shan Liu, Luca Paruzzo +7 more

Optimal pairing of binder and co-stimulatory domains improves dual CART cell efficacy

Molecular Therapy(2025)10.1016/j.ymthe.2025.08.002

N/A

0.247DataRank · unranked

4 citations

Sasikanth Manne, Shuguang Jiang, Marco Ruella, E. John Wherry, James L. Riley +1 more

EZH2 INHIBITION ENHANCES CAR T ANTITUMOR EFFECT BY INDUCING LYMPHOMA IMMUNOGENICITY AND ENHANCING T CELL FUNCTION

Hematological Oncology(2023)10.1002/hon.3163_149

N/A

0.165DataRank · unranked

2 citations

Patrizia Porazzi, Ari Melnick, Marco Ruella, Wendy Béguelin, Yusuke Isshiki

Leveraging immune resistance archetypes in solid cancer to inform next-generation anticancer therapies

Journal for ImmunoTherapy of Cancer(2023)10.1136/jitc-2022-006533

N/A

0DataRank · unranked

20 citations

David A. Braun, Aitziber Buqué, Sarah B. Gitto, Jennifer L. Guerriero, Brendan Horton +9 more

ALKemy to enhance chimeric antigen receptor T cell immunotherapy for neuroblastoma

Cancer Cell(2023)10.1016/j.ccell.2023.11.009

N/A

0DataRank · unranked

2 citations

Marco Ruella

Alternative splicing of its 5’-UTR limits CD20 mRNA translation and enables resistance to CD20-directed immunotherapies

bioRxiv (Cold Spring Harbor Laboratory)(2023)10.1101/2023.02.19.529123

N/A

0DataRank · unranked

5 citations

Luca Paruzzo, Katharina E. Hayer, Carolin Schmidt, Manuel Torres-Diz, Feng Xu +19 more

The long road to the first FDA-approved gene therapy: chimeric antigen receptor T cells targeting CD19

Cytotherapy(2020)10.1016/j.jcyt.2019.12.004

N/A

0DataRank · unranked

155 citations

Bruce L. Levine, Marco Ruella, Peter Brændstrup

Immunologic predictors of vaccine responsiveness in patients with lymphoma and CLL

medRxiv(2023)10.1101/2023.09.26.23295903

N/A

0DataRank · unranked

0 citations

Kingsley Gideon Kumashie, Emeline R. Chong, Joseph Fabrizio, Aditi Gupta, Jakub Svoboda +38 more

EZH2 inhibition enhances T cell immunotherapies by inducing lymphoma immunogenicity and improving T cell function

Cancer Cell(2024)10.1016/j.ccell.2024.11.006

N/A

0DataRank · unranked

61 citations

Xi Chen, Matt Teater, Ioannis Karagiannidis, Henna S. Nam, Winson Cai +20 more

CD5 deletion enhances the antitumor activity of adoptive T cell therapies

Science Immunology(2024)10.1126/sciimmunol.adn6509

N/A

0DataRank · unranked

48 citations

Guido Ghilardi, Yunlin Zhang, Yi‐Hao Chiang, Wei Xie, Puneeth Guruprasad +46 more

Efficacy and safety of bendamustine for lymphodepletion before lisocabtagene maraleucel

Journal of Hematology & Oncology(2024)10.1186/s13045-024-01542-9

N/A

0DataRank · unranked

11 citations

Luca Paruzzo, Vrutti Patel, Jakub Svoboda, Emeline R. Chong, Eugenio Fardella +15 more

Exploiting the CD200-CD200R immune checkpoint axis in multiple myeloma to enhance CAR T-cell therapy

Blood(2023)10.1182/blood.2022018658

N/A

0DataRank · unranked

22 citations

Wei Liu, Siddhant Kadu, Omar Johnson, Zainul S. Hasanali, Andre Kelly +15 more

CAR T-cell Resistance to Oncogenic Transformation

Blood Cancer Discovery(2024)10.1158/2643-3230.bcd-23-0273

N/A

0DataRank · unranked

3 citations

Carl H. June, Marco Ruella

Directed evolution-based discovery of ligands for in vivo restimulation of CAR-T cells

bioRxiv (Cold Spring Harbor Laboratory)(2024)10.1101/2024.04.16.589780

N/A

0DataRank · unranked

2 citations

Alexandra Neeser, Ranjani Ramasubramanian, Anna Romanov, Ryan Tannir, Naveen K. Mehta +23 more

Modulation of the gut microbiota engages antigen cross-presentation to enhance antitumor effects of CAR T cell immunotherapy

Molecular Therapy(2023)10.1016/j.ymthe.2023.01.012

N/A

0DataRank · unranked

59 citations

Silvia Beghi, Marco Ruella, Kalpana Parvathaneni, Silvano Salaris, Νεκτάριος Κωστόπουλος +23 more

Deletion of the inhibitory co-receptor CTLA-4 enhances and invigorates chimeric antigen receptor T cells

Immunity(2023)10.1016/j.immuni.2023.09.001

N/A

0DataRank · unranked

171 citations

M. Ángela Aznar, Andrew J. Rech, Charly R. Good, Shunichiro Kuramitsu, Tong Da +15 more

Directed evolution-based discovery of ligands for in vivo restimulation of chimeric antigen receptor T cells

Nature Biomedical Engineering(2025)10.1038/s41551-025-01470-0

N/A

0DataRank · unranked

3 citations

Alexandra Neeser, Ranjani Ramasubramanian, Anna Romanov, Ryan Tannir, Naveen K. Mehta +23 more

DLBCL Cells Emerge after CD19 CAR T Cells with Cross-Antigen Resistance and a Gene Signature Predictive of Clinical CAR T-cell Response

Blood Cancer Discovery(2025)10.1158/2643-3230.bcd-24-0176

N/A

0DataRank · unranked

1 citations

Jeanne Whalen, Youngchul Song, Kalyn Schriefer, Rick Newcombe, Elena J. Orlando +8 more

18F-Fluorodeoxyglucose Positron Emission Tomography/Computed Tomography Following Chimeric Antigen Receptor T-cell Therapy in Large B-cell Lymphoma

Molecular Imaging and Biology(2021)10.1007/s11307-021-01627-8

N/A

0DataRank · unranked

13 citations

Hatcher J. Ballard, Austin R. Pantel, Esin C. Namoglu, Mitchell E. Hughes, Sunita D. Nasta +7 more

The current landscape of single-cell transcriptomics for cancer immunotherapy

The Journal of Experimental Medicine(2020)10.1084/jem.20201574

N/A

0DataRank · unranked

62 citations

Yong Gu Lee, Ki Hyun Kim, Marco Ruella, Puneeth Guruprasad