Sarat Chandarlapaty

Also affiliated with Cornell University, Kettering University

MedicineBiochemistry, Genetics and Molecular Biology

Pilot corpus only

This score is computed over theSindex pilot corpus and does not cover the full scientific literature. Scores are relative to papers we have ingested — papers, authors, and institutions outside the pilot are not represented. Methodology.

Top 100%percentile

0Author DataRank

Indexed papers

2in pilot corpus

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Why this DataRank?

An author's DataRank is the sum of the DataRanks of all 2 indexed papers attributed to them. A prolific author with many moderate-impact papers can outrank one with a single high-impact paper.

Author scores recompute whenever paper DataRanks are refreshed, so this number lags the underlying paper scores by at most one batch run.

Read the full methodology →

Papers

Driven by 53 papers. Top paper: “Capivasertib, an AKT Kinase Inhibitor, as Monotherapy or in Combination with Fulvestrant in Patients with AKT1 E17K-Mutant, ER-Positive Metastatic Breast Cancer”.

Capivasertib, an AKT Kinase Inhibitor, as Monotherapy or in Combination with Fulvestrant in Patients with AKT1 E17K-Mutant, ER-Positive Metastatic Breast Cancer

Clinical Cancer Research(2020)10.1158/1078-0432.ccr-19-3953

N/A

3.2DataRank · unranked

108 citations

Kenji Tamura, Mafalda Oliveira, Eva Ciruelos, Ingrid A. Mayer, Marie‐Paule Sablin +23 more

Identification of HER2-Positive Metastases in Patients with HER2-Negative Primary Breast Cancer by Using HER2-targeted 89Zr-Pertuzumab PET/CT

Radiology(2020)10.1148/radiol.2020192828

N/A

2.1DataRank · unranked

70 citations

Jorge A. Carrasquillo, Christopher C. Riedl, Randy Yeh, Vaios Hatzoglou, Dara S. Ross +7 more

AMEERA-1 phase 1/2 study of amcenestrant, SAR439859, in postmenopausal women with ER-positive/HER2-negative advanced breast cancer

Nature Communications(2022)10.1038/s41467-022-31668-8

N/A

2.0DataRank · unranked

54 citations

Sarat Chandarlapaty, Hannah M. Linden, Gary A. Ulaner, Alice Gosselin, Sylvaine Cartot‐Cotton +12 more

Selective AKT kinase inhibitor capivasertib in combination with fulvestrant in PTEN-mutant ER-positive metastatic breast cancer

npj Breast Cancer(2021)10.1038/s41523-021-00251-7

N/A

1.4DataRank · unranked

36 citations

Gerald Batist, Funda Meric‐Bernstam, Peter Kabos, Iben Spanggaard, Aňa Lluch +22 more

TERT promoter hotspot mutations and gene amplification in metaplastic breast cancer

npj Breast Cancer(2021)10.1038/s41523-021-00250-8

N/A

1.1DataRank · unranked

31 citations

Pier Selenica, Mahsa Vahdatinia, Fresia Pareja, Arnaud Da Cruz Paula, Lorenzo Ferrando +14 more

Genomic characterization of metastatic patterns from prospective clinical sequencing of 25,000 patients

Cell(2022)10.1016/j.cell.2022.01.003

N/A

0.973DataRank · unranked

654 citations

Christopher J. Fong, Anisha Luthra, Shaleigh Smith, Renzo G. DiNatale, Subhiksha Nandakumar +70 more

Enhanced specificity of clinical high-sensitivity tumor mutation profiling in cell-free DNA via paired normal sequencing using MSK-ACCESS

Nature Communications(2021)10.1038/s41467-021-24109-5

N/A

0.782DataRank · unranked

183 citations

Gowtham Jayakumaran, Monica Diosdado, Juber Patel, Anna Razumova, Yu Hu +64 more

Systemic Therapy for Advanced Human Epidermal Growth Factor Receptor 2–Positive Breast Cancer: ASCO Guideline Update

Journal of Clinical Oncology(2022)10.1200/jco.22.00519

N/A

0.778DataRank · unranked

178 citations

Maria Alice Franzoi, Sarah Temin, Carey K. Anders, Sarat Chandarlapaty, Jennie R. Crews +9 more

Rise of Antibody-Drug Conjugates: The Present and Future

American Society of Clinical Oncology Educational Book(2023)10.1200/edbk_390094

N/A

0.700DataRank · unranked

105 citations

Avantika Gupta, Sarat Chandarlapaty, Matthew Young, Thomas Powles, Erika Hamilton +1 more

Sequential activation of E2F via Rb degradation and c-Myc drives resistance to CDK4/6 inhibitors in breast cancer

Cell Reports(2023)10.1016/j.celrep.2023.113198

N/A

0.612DataRank · unranked

58 citations

Jessica Armand, Anton Safonov, Mimi Zhang, Rajesh K. Soni, Gary K. Schwartz +7 more

AKT1 E17K Inhibits Cancer Cell Migration by Abrogating β-Catenin Signaling

Molecular Cancer Research(2020)10.1158/1541-7786.mcr-20-0623

N/A

0.464DataRank · unranked

21 citations

Amber J. Kiliti, Kai Zhang, Naresh Vasani, Ninghui Mao, Emmet Jordan +14 more

Adrenal-permissive HSD3B1 genetic inheritance and risk of estrogen-driven postmenopausal breast cancer

JCI Insight(2021)10.1172/jci.insight.150403

N/A

0.457DataRank · unranked

20 citations

Mona Patel, Jeffrey M. McManus, Yoon‐Mi Chung, Xiuxiu Li, Wei Wei +15 more

Pan-cancer analysis of biallelic inactivation in tumor suppressor genes identifies KEAP1 zygosity as a predictive biomarker in lung cancer

Cell(2024)10.1016/j.cell.2024.11.010

N/A

0.449DataRank · unranked

19 citations

Maria Perry, Samuel I. Gould, Arielle Elkrief, Anton Safonov, Rohit Thummalapalli +23 more

Long-term breast cancer response to CDK4/6 inhibition defined by TP53-mediated geroconversion

Cancer Cell(2024)10.1016/j.ccell.2024.10.013

N/A

0.416DataRank · unranked

15 citations

Anton Safonov, Catherine Jones, Enrico Moiso, Jonathan R. Dry, Hong Shao +22 more

Incidence of HER2-expressing brain metastases in patients with HER2-null breast cancer: a matched case analysis

npj Breast Cancer(2023)10.1038/s41523-023-00592-5

N/A

0.396DataRank · unranked

13 citations

Jolene M. Singh, Anne S. Reiner, Joshua Z. Drago, Shanu Modi, Andrew D. Seidman +3 more

eIF4A controls translation of estrogen receptor alpha and is a therapeutic target in advanced breast cancer

Proceedings of the National Academy of Sciences(2025)10.1073/pnas.2424286122

N/A

0.382DataRank · unranked

9 citations

Ezra Y. Rosen, Malvika Sharma, M. Dorso, Nicholas Mai, Corina Amor +22 more

Utility of Serial cfDNA NGS for Prospective Genomic Analysis of Patients on a Phase I Basket Study

JCO Precision Oncology(2021)10.1200/po.20.00184

N/A

0.365DataRank · unranked

5 citations

Jonathan Reichel, Jiabin Tang, Juber Patel, Fanli Meng, Duygu Selcuklu +15 more

RB1 Genetic Alterations in Estrogen Receptor–Positive Breast Carcinomas: Correlation With Neuroendocrine Differentiation

Modern Pathology(2024)10.1016/j.modpat.2024.100541

N/A

0.360DataRank · unranked

10 citations

Antonio Marra, Pier Selenica, Andrea Gazzo, Kiki Tan, Dara S. Ross +8 more

Recurrent WWTR1S89W mutations and Hippo pathway deregulation in clear cell carcinomas of the cervix

The Journal of Pathology(2022)10.1002/path.5910

N/A

0.360DataRank · unranked

10 citations

Thais Basili, Higinio Dopeso, Arnaud Da Cruz Paula, Rui Bi, Shirin Issa Bhaloo +23 more

Final analysis of multi-histology basket trial expansion of ado-trastuzumab emtansine in patients with HER2 amplified cancers.

Journal of Clinical Oncology(2023)10.1200/jco.2023.41.16_suppl.3025

N/A

0.345DataRank · unranked

9 citations

Vicky Makker, Darren J. Buonocore, Ronglai Shen, Rona Yaeger, Michelle S. Ginsberg +15 more

Whole‐exome sequencing analysis of juvenile papillomatosis and coexisting breast carcinoma

The Journal of Pathology Clinical Research(2020)10.1002/cjp2.190

N/A

0.330DataRank · unranked

8 citations

Fresia Pareja, Arnaud Da Cruz Paula, Mahsa Vahdatinia, Andrea Gazzo, Lorenzo Ferrando +11 more

Determinants of sensitivity to HER2-targeted antibody drug conjugates in urothelial cancer

Nature Communications(2025)10.1038/s41467-025-67643-2

N/A

0.292DataRank · unranked

6 citations

Xinran Tang, Jordan Eichholz, Andrew McPherson, Jasmine Thomas, Karan Nagar +23 more

Optimal systemic treatment and real-world clinical application of ctDNA in patients with metastatic HER2-mutant lung cancer

European Journal of Cancer(2024)10.1016/j.ejca.2024.114257

N/A

0.269DataRank · unranked

5 citations

Tatiana Erazo, Justin Jee, Andrea Arfè, Avantika Gupta, Luke Pike +28 more

Predictors of response to neoadjuvant chemo-immunotherapy in metaplastic triple-negative breast cancer

npj Breast Cancer(2025)10.1038/s41523-025-00816-w

N/A

0.208DataRank · unranked

3 citations

Fresia Pareja, Charlie White, Yuan Chen, Hannah Y. Wen, Esra Dikoglu +11 more

eIF4A controls translation of estrogen receptor alpha and is a therapeutic target in advanced breast cancer

bioRxiv (Cold Spring Harbor Laboratory)(2024)10.1101/2024.05.08.593195

N/A

0.165DataRank · unranked

2 citations

Malvika Sharma, M. Dorso, Nicholas Mai, Corina Amor, Jason Reiter +21 more

Evolution and Co-occurrence of PI3K Pathway Gene Mutations in Endometrial Carcinoma Molecular Subtypes at the Single-Cell Level

Clinical Cancer Research(2025)10.1158/1078-0432.ccr-25-1237

N/A

0.165DataRank · unranked

2 citations

Yingjie Zhu, David N. Brown, Shirin Issa Bhaloo, Fresia Pareja, Timothy Hoang +11 more

Interim analysis of a single-center, single-arm, prospective phase 2 study to evaluate the efficacy and safety of benralizumab for alpelisib rash in metastatic PIK3CA-mutant, hormone receptor–positive breast cancer.

Journal of Clinical Oncology(2022)10.1200/jco.2022.40.16_suppl.12100

N/A

0.165DataRank · unranked

2 citations

Alexander Pan, George Dranitsaris, Ucalene Harris, Sarat Chandarlapaty, Chau T. Dang +11 more

Genomic landscape of breast cancer in elderly patients

npj Breast Cancer(2025)10.1038/s41523-025-00781-4

N/A

0.165DataRank · unranked

2 citations

Higinio Dopeso, Matteo Repetto, Thais Basili, Andrea Gazzo, Christopher J. Schwartz +16 more

HER2 persistence after treatment with T-DXd in breast and gastrointestinal cancers.

Journal of Clinical Oncology(2023)10.1200/jco.2023.41.16_suppl.1052

N/A

0DataRank · unranked

6 citations

Fresia Pareja, Komal Jhaveri, Elaine M. Walsh, Geoffrey Y. Ku, Steven B. Maron +7 more

Management of patients with advanced-stage HER2-positive breast cancer: current evidence and future perspectives

Nature Reviews Clinical Oncology(2024)10.1038/s41571-023-00849-9

N/A

0DataRank · unranked

106 citations

Sarat Chandarlapaty, Shanu Modi, Antonio Marra

Long-term breast cancer response to CDK4/6 inhibition defined by TP53-mediated geroconversion

Cancer Cell(2024)10.1016/j.ccell.2024.09.009

N/A

0DataRank · unranked

49 citations

Anton Safonov, Catherine Jones, Enrico Moiso, Jonathan R. Dry, Hong Shao +23 more

EGFR-directed antibodies promote HER2 ADC internalization and efficacy

Cell Reports Medicine(2024)10.1016/j.xcrm.2024.101792

N/A

0DataRank · unranked

31 citations

Flavia Michelini, Hong Shao, Celine Yeh, Joshua Z. Drago, Dazhi Liu +12 more

A Genomics-Driven Artificial Intelligence – Based Model Classifies Breast Invasive Lobular Carcinoma and Discovers CDH1 Inactivating Mechanisms

Cancer Research(2024)10.1158/0008-5472.can-24-1322

N/A

0DataRank · unranked

20 citations

Higinio Dopeso, Yi Kan Wang, Andrea Gazzo, David N. Brown, Monami Banerjee +34 more

A Phase II Study of Fulvestrant plus Abemaciclib in Hormone Receptor–Positive Advanced or Recurrent Endometrial Cancer

Clinical Cancer Research(2024)10.1158/1078-0432.ccr-24-1999

N/A

0DataRank · unranked

16 citations

Qin Zhou, Alexia Iasonos, William A. Zammarrelli, Britta Weigelt, Lora H. Ellenson +17 more

Personalized cancer therapy prioritization based on driver alteration co-occurrence patterns

Genome Medicine(2020)10.1186/s13073-020-00774-x

N/A

0DataRank · unranked

23 citations

Miquel Duran‐Frigola, Albert Gris‐Oliver, Marta Palafox, Maurizio Scaltriti, Pedram Razavi +6 more

Trastuzumab Deruxtecan Resistance via Loss of HER2 Expression and Binding

Cancer Discovery(2025)10.1158/2159-8290.cd-25-0647

N/A

0DataRank · unranked

21 citations

Avantika Gupta, Nicholas Mai, Sharanya Nag, Joshua Lau, Sukrit Singh +12 more

Loss of Kmt2c or Kmt2d primes urothelium for tumorigenesis and redistributes KMT2A–menin to bivalent promoters

Nature Genetics(2025)10.1038/s41588-024-02015-y

N/A

0DataRank · unranked

17 citations

Mohini R. Pachai, Dan Li, Cindy J. Lee, Sarah Warda, Makhzuna N. Khudoynazarova +25 more

Enrichment of kinase fusions in ESR1 wild-type, metastatic breast cancer revealed by a systematic analysis of 4854 patients

Annals of Oncology(2020)10.1016/j.annonc.2020.04.008

N/A

0DataRank · unranked

33 citations

Bo Liu, Alison M. Schram, Pedram Razavi, Stephen M. Lagana, Y. Zhang +10 more

Genomic Alterations in PIK3CA -Mutated Breast Cancer Result in mTORC1 Activation and Limit the Sensitivity to PI3Kα Inhibitors

Cancer Research(2021)10.1158/0008-5472.can-20-3232

N/A

0DataRank · unranked

35 citations

Guotai Xu, Fan Wu, Flavia Michelini, Carmen Chan, Xuan Qu +16 more

The genomic landscape of metastatic histologic special types of invasive breast cancer

npj Breast Cancer(2020)10.1038/s41523-020-00195-4

N/A

0DataRank · unranked

48 citations

Lorenzo Ferrando, Simon Lee, Francisco Beça, Pier Selenica, David N. Brown +13 more

HER2 + breast cancers evade anti-HER2 therapy via a switch in driver pathway

Nature Communications(2021)10.1038/s41467-021-27093-y

N/A

0DataRank · unranked

88 citations

Emanuela Ferraro, Anton Safonov, Cristina Bernadó Morales, Enrique J. Arenas, Qing Li +10 more

Defining the Energetic Basis for a Conformational Switch Mediating Ligand-Independent Activation of Mutant Estrogen Receptors in Breast Cancer

Molecular Cancer Research(2021)10.1158/1541-7786.mcr-20-1017

N/A

0DataRank · unranked

13 citations

Weiyi Toy, Kathryn E. Carlson, Trusha Bhatt, Sean W. Fanning, Geoffrey L. Greene +5 more

Adrenal-permissive HSD3B1 genetic inheritance and risk of estrogen-driven postmenopausal breast cancer.

Journal of Clinical Oncology(2021)10.1200/jco.2021.39.15_suppl.10503

N/A

0DataRank · unranked

0 citations

Megan Kruse, Jeffrey M. McManus, Yoon‐Mi Chung, Wei Wei, Peter Bazeley +13 more

ERα-LBD, a novel isoform of estrogen receptor alpha, promotes breast cancer proliferation and endocrine resistance

bioRxiv (Cold Spring Harbor Laboratory)(2021)10.1101/2021.10.14.464262

N/A

0DataRank · unranked

0 citations

Pasquale Sansone, Vinagolu K. Rajasekhar, Mesruh Turkekul, Vitaly Boyko, Fanli Meng +19 more

Regulation of PTEN translation by PI3K signaling maintains pathway homeostasis

Molecular Cell(2021)10.1016/j.molcel.2021.01.033

N/A

0DataRank · unranked

135 citations

Kiran Vanaja, Jacob A. Boyer, Sunyana Gadal, Hilla Solomon, Sarat Chandarlapaty +3 more

INK4 Tumor Suppressor Proteins Mediate Resistance to CDK4/6 Kinase Inhibitors

Cancer Discovery(2021)10.1158/2159-8290.cd-20-1726

N/A

0DataRank · unranked

166 citations

Baishan Jiang, Jiaye Guo, Hong Shao, Isabella Del Priore, Qing Chang +20 more

Accelerating drug development in breast cancer: New frontiers for ER inhibition

Cancer Treatment Reviews(2022)10.1016/j.ctrv.2022.102432

N/A

0DataRank · unranked

52 citations

Elaine M. Walsh, Jacqueline J. Tao, Sarat Chandarlapaty, Komal Jhaveri, Emanuela Ferraro

PRC2-Inactivating Mutations in Cancer Enhance Cytotoxic Response to DNMT1-Targeted Therapy via Enhanced Viral Mimicry

Cancer Discovery(2022)10.1158/2159-8290.cd-21-1671

N/A

0DataRank · unranked

33 citations

Sarah Warda, Jesper L.V. Mååg, Rohan Misra, Miguel A. Miranda-Román, Mohini R. Pachai +22 more

ERα-LBD, an isoform of estrogen receptor alpha, promotes breast cancer proliferation and endocrine resistance

npj Breast Cancer(2022)10.1038/s41523-022-00470-6

N/A

0DataRank · unranked

25 citations

Pasquale Sansone, Vinagolu K. Rajasekhar, Mesruh Turkekul, Vitaly Boyko, Fanli Meng +21 more

Ash1, a Daughter Cell-Specific Protein, Is Required for Pseudohyphal Growth ofSaccharomyces cerevisiae

UNC Libraries(2020)10.17615/7mcx-eb76

N/A

0DataRank · unranked

0 citations

Sarat Chandarlapaty, Beverly Errede

ESR1 F404 Mutations and Acquired Resistance to Fulvestrant in ESR1 -Mutant Breast Cancer

Cancer Discovery(2023)10.1158/2159-8290.cd-22-1387

N/A

0DataRank · unranked

38 citations

Alex Pearson, María Teresa Herrera-Abreu, Li-Xuan Sim, Rosalind Cutts, Heena Shah +12 more

Nonlobular Invasive Breast Carcinomas with Biallelic Pathogenic CDH1 Somatic Alterations: A Histologic, Immunophenotypic, and Genomic Characterization

Modern Pathology(2023)10.1016/j.modpat.2023.100375

N/A

0DataRank · unranked

5 citations

Arnaud Da Cruz Paula, Pier Selenica, Edaise M. da Silva, Anne Grabenstetter, Sahar Jalali +15 more

A Druggable FOXA1-Glucocorticoid Receptor Transcriptional Axis Drives Tumor Growth in a Subset of Non-Small Cell Lung Cancer

Cancer Research Communications(2023)10.1158/2767-9764.crc-23-0310

N/A

0DataRank · unranked

4 citations

Payal T. Patel, Aleksandr Pankov, Jacob A. Boyer, Rajesh K. Soni, Isabella Del Priore +10 more