Brian Kuhlman

University of North Carolina at Chapel Hill

Also affiliated with UNC Lineberger Comprehensive Cancer Center

Biochemistry, Genetics and Molecular BiologyMaterials ScienceMedicine

Pilot corpus only

This score is computed over theSindex pilot corpus and does not cover the full scientific literature. Scores are relative to papers we have ingested — papers, authors, and institutions outside the pilot are not represented. Methodology.

Top 100%percentile

0Author DataRank

Indexed papers

1in pilot corpus

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Why this DataRank?

An author's DataRank is the sum of the DataRanks of all 1 indexed paper attributed to them. A prolific author with many moderate-impact papers can outrank one with a single high-impact paper.

Author scores recompute whenever paper DataRanks are refreshed, so this number lags the underlying paper scores by at most one batch run.

Read the full methodology →

The highest-impact dataset this researcher has shared, ranked by DataRank — the single contribution doing the most to lift their data-sharing standing.

UbSRD: The Ubiquitin Structural Relational Database

UNC Libraries(2020)10.17615/wtv9-da72

Top 100%

0DataRank

Top 100%0 citations

Joseph S. Harrison, Koenraad Van Doorslaer, Kevin Houlihan, Brian Kuhlman, Timothy M. Jacobs

Papers

Driven by 95 papers — median percentile 0. Top paper: “Advances in protein structure prediction and design”.

Advances in protein structure prediction and design

Nature Reviews Molecular Cell Biology(2019)10.1038/s41580-019-0163-x

N/A

8.3DataRank · unranked

816 citations

Philip Bradley, Brian Kuhlman

E2 conjugating enzymes must disengage from their E1 enzymes before E3-dependent ubiquitin and ubiquitin-like transfer

Nature Structural & Molecular Biology(2005)10.1038/nsmb984

N/A

7.2DataRank · unranked

156 citations

Danny T Huang, David M Duda, Brenda A Schulman, Brian Kuhlman, Ziad M Eletr

High-resolution design of a protein loop

Proceedings of the National Academy of Sciences(2007)10.1073/pnas.0707977104

N/A

5.7DataRank · unranked

124 citations

Huanchen Wang, Hengming Ke, Brian Kuhlman, Xiaozhen Hu

Modifications to the Framework Regions Eliminate Chimeric Antigen Receptor Tonic Signaling

Cancer Immunology Research(2021)10.1158/2326-6066.cir-20-0451

N/A

0.655DataRank · unranked

78 citations

Giovanni Fucà, Jian Wang, Venkat R. Chirasani, Zhiyuan Yao, Elena Dukhovlinova +14 more

Engineering a tumor-selective prodrug T-cell engager bispecific antibody for safer immunotherapy

mAbs(2024)10.1080/19420862.2024.2373325

N/A

0.595DataRank · unranked

18 citations

Stephen J. Demarest, Karen Froning, Michael J. Hickey, Stephen Antonysamy, Brian Kuhlman +1 more

Computational de novo design of a four-helix bundle protein - DND-4HB

UNC Libraries(2020)10.17615/whzq-hj05

N/A

0DataRank · unranked

1 citations

S. Pulavarti, Mischa Machius, Brian Kuhlman, Thomas Szyperski, Bryan S. Der +2 more

An optogenetic switch for the Set2 methyltransferase provides evidence for transcription-dependent and -independent dynamics of H3K36 methylation

Genome Research(2020)10.1101/gr.264283.120

N/A

0DataRank · unranked

17 citations

Austin J. Hepperla, Gregory R. Keele, Hashem A. Meriesh, Hayretin Yumerefendi, David Restrepo +6 more

PyRosetta Jupyter Notebooks Teach Biomolecular Structure Prediction and Design

Preprints.org(2020)10.20944/preprints202002.0097.v1

N/A

0DataRank · unranked

4 citations

Jared Adolf‐Bryfogle, Jason C. Klima, Sergey Lyskov, Jason W. Labonte, Steven J. Bertolani +16 more

Structural Determinants of Affinity Enhancement between GoLoco Motifs and G-Protein α Subunit Mutants

UNC Libraries(2020)10.17615/n9sj-7249

N/A

0DataRank · unranked

0 citations

Deanne W. Sammond, Francis S. Willard, Adam J. Kimple, Mischa Machius, Michael J. Miley +4 more

Redesign of the PAK1 Autoinhibitory Domain for Enhanced Stability and Affinity in Biosensor Applications

UNC Libraries(2020)10.17615/amyx-j521

N/A

0DataRank · unranked

0 citations

Chris MacNevin, Klaus M. Hahn, Ramesh K. Jha, Brian Kuhlman, Yi Wu +1 more

UbSRD: The Ubiquitin Structural Relational Database

UNC Libraries(2020)10.17615/wtv9-da72

Top 100%

0DataRank

Top 100%0 citations

Joseph S. Harrison, Koenraad Van Doorslaer, Kevin Houlihan, Brian Kuhlman, Timothy M. Jacobs

Using quantum mechanics to improve estimates of amino acid side chain rotamer energies

UNC Libraries(2020)10.17615/m8s1-nk62

N/A

0DataRank · unranked

0 citations

P. Douglas Renfrew, Brian Kuhlman, Glenn L. Butterfoss

Control of Protein Activity and Cell Fate Specification via Light-Mediated Nuclear Translocation

UNC Libraries(2020)10.17615/6qr8-w815

N/A

0DataRank · unranked

0 citations

Brian Kuhlman, Daniel J. Dickinson, James E. Bear, Klaus M. Hahn, Seth P. Zimmerman +3 more

A Generic Program for Multistate Protein Design

UNC Libraries(2020)10.17615/wvx4-nh86

N/A

0DataRank · unranked

0 citations

Andrew Leaver-Fay, P. Benjamin Stranges, Brian Kuhlman, Ron Jacak

Scientific Benchmarks for Guiding Macromolecular Energy Function Improvement

UNC Libraries(2020)10.17615/a2jg-d649

N/A

0DataRank · unranked

0 citations

Jane S. Richardson, Ian Davis, Ron Jacak, Andrew Leaver-Fay, Roland A. Pache +12 more

A genetically encoded photoactivatable Rac controls the motility of living cells

UNC Libraries(2020)10.17615/1f73-5m59

N/A

0DataRank · unranked

0 citations

Brian Kuhlman, Ilme Schlichting, Daniel Frey, Yi Wu, Oana I. Lungu +2 more

Computational protein design with explicit consideration of surface hydrophobic patches

UNC Libraries(2020)10.17615/szz9-zz38

N/A

0DataRank · unranked

0 citations

Ron Jacak, Brian Kuhlman, Andrew Leaver-Fay

Computational design of affinity and specificity at protein–protein interfaces

UNC Libraries(2020)10.17615/g42d-mf39

N/A

0DataRank · unranked

0 citations

Brian Kuhlman, John Karanicolas

Structure-based Protocol for Identifying Mutations that Enhance Protein–Protein Binding Affinities

UNC Libraries(2020)10.17615/2h87-gp22

N/A

0DataRank · unranked

0 citations

Carrie Purbeck, David P. Siderovski, Deanne W. Sammond, Brian Kuhlman, Randall J. Kimple +1 more

Computational design of second-site suppressor mutations at protein-protein interfaces

UNC Libraries(2020)10.17615/hne9-y896

N/A

0DataRank · unranked

0 citations

Carrie Purbeck, Deanne W. Sammond, Ziad M. Eletr, Brian Kuhlman

Tuning the Binding Affinities and Reversion Kinetics of a Light Inducible Dimer Allows Control of Transmembrane Protein Localization

INDIGO (University of Illinois at Chicago)(2020)10.17615/sy9k-m240

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0DataRank · unranked

0 citations

James E. Bear, Brian Kuhlman, Ryan A. Hallett, Matthew J. Kennedy, Ashley M. Bourke +1 more

Metal-Mediated Affinity and Orientation Specificity in a Computationally Designed Protein Homodimer

Figshare(2020)10.17615/hz9m-by10

N/A

0DataRank · unranked

0 citations

Jeffrey Mills, Brian Kuhlman, Mischa Machius, Bryan S. Der, Michael J. Miley +1 more

Serverification of Molecular Modeling Applications: The Rosetta Online Server That Includes Everyone (ROSIE)

UNC Libraries(2020)10.17615/7c93-y342

N/A

0DataRank · unranked

0 citations

Tanja Kortemme, Benjamin Borgo, James J. Havranek, Fang‐Chieh Chou, Bryan S. Der +12 more

Functional Class I and II Amino Acid-activating Enzymes Can Be Coded by Opposite Strands of the Same Gene

UNC Libraries(2020)10.17615/0che-gh49

N/A

0DataRank · unranked

0 citations

Luis Martínez‐Rodríguez, Srinivas Niranj Chandrasekaran, Brian Kuhlman, Mariel Jimenez-Rodriguez, Li Li +7 more

Alternative Computational Protocols for Supercharging Protein Surfaces for Reversible Unfolding and Retention of Stability

UNC Libraries(2020)10.17615/d0j8-zf32

N/A

0DataRank · unranked

0 citations

George Georgiou, Ron Jacak, Jeffrey J. Gray, Brian Kuhlman, Sergey Lyskov +4 more

Dual RING E3 Architectures Regulate Multiubiquitination and Ubiquitin Chain Elongation by APC/C

UNC Libraries(2020)10.17615/kssb-fk64

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0DataRank · unranked

0 citations

David Yanishevski, Nicholas G. Brown, Darcie J. Miller, Brenda A. Schulman, M. Yamaguchi +24 more

Computational Design of a PAK1 Binding Protein

UNC Libraries(2020)10.17615/t43c-a350

N/A

0DataRank · unranked

0 citations

Brian Kuhlman, Ramesh K. Jha, Thomas Szyperski, Yibing Wu, Andrew Leaver-Fay +3 more

The Rosetta All-Atom Energy Function for Macromolecular Modeling and Design

UNC Libraries(2020)10.17615/6sk2-v510

N/A

0DataRank · unranked

0 citations

Matthew J. O’Meara, Philip Bradley, Maxim V. Shapovalov, Rhiju Das, Hahnbeom Park +15 more

Using anchoring motifs for the computational design of protein–protein interactions

UNC Libraries(2020)10.17615/b04x-tw86

N/A

0DataRank · unranked

0 citations

Brian Kuhlman, Timothy M. Jacobs

Designing Photoswitchable Peptides Using the AsLOV2 Domain

UNC Libraries(2020)10.17615/tsze-2a55

N/A

0DataRank · unranked

0 citations

Oana I. Lungu, Mary J. Aiken, Ryan A. Hallett, Brian Kuhlman, Klaus M. Hahn +1 more

Essential Role for Ubiquitin-Ubiquitin-Conjugating Enzyme Interaction in Ubiquitin Discharge from Cdc34 to Substrate

UNC Libraries(2020)10.17615/wjgb-mn48

N/A

0DataRank · unranked

0 citations

Steven Lewis, Raymond J. Deshaies, Anjanabha Saha, Gary Kleiger, Brian Kuhlman

SwiftLib: rapid degenerate-codon-library optimization through dynamic programming

UNC Libraries(2020)10.17615/zq7n-bs80

N/A

0DataRank · unranked

0 citations

Andrew Leaver-Fay, Timothy M. Jacobs, Brian Kuhlman, Hayretin Yumerefendi

Site-specific monoubiquitination activates Ras by impeding GTPase-activating protein function

UNC Libraries(2020)10.17615/1ca2-0y14

N/A

0DataRank · unranked

0 citations

Rachael Baker, Lewis C. Cantley, Emily Wilkerson, Steven M. Lewis, Brian Kuhlman +4 more

Adding Diverse Noncanonical Backbones to Rosetta: Enabling Peptidomimetic Design

UNC Libraries(2020)10.17615/xrww-m716

N/A

0DataRank · unranked

0 citations

Brooke N. Bullock, Richard Bonneau, Paramjit S. Arora, Kent Kirshenbaum, Timothy W. Craven +14 more

Requirements for 5′dRP/AP lyase activity in Ku

UNC Libraries(2020)10.17615/6320-z898

N/A

0DataRank · unranked

0 citations

Dale A. Ramsden, Brian Kuhlman, Ryan A. Hallett, Steven A. Roberts, Christina Strom +3 more

Rapid E2-E3 Assembly and Disassembly Enable Processive Ubiquitylation of Cullin-RING Ubiquitin Ligase Substrates

UNC Libraries(2020)10.17615/7baf-c392

N/A

0DataRank · unranked

0 citations

Raymond J. Deshaies, Steven M. Lewis, Gary Kleiger, Brian Kuhlman, Anjanabha Saha

Go in! Go out! Inducible control of nuclear localization

UNC Libraries(2020)10.17615/xwk3-tw56

N/A

0DataRank · unranked

0 citations

Barbara Di Ventura, Brian Kuhlman

Mechanism of Lysine 48 Selectivity during Polyubiquitin Chain Formation by the Ube2R1/2 Ubiquitin-Conjugating Enzyme

UNC Libraries(2020)10.17615/sn40-p981

N/A

0DataRank · unranked

0 citations

Joseph S. Harrison, Brian Kuhlman, Gary Kleiger, Spencer Hill, Steven M. Lewis

Engineering an improved light-induced dimer (iLID) for controlling the localization and activity of signaling proteins

UNC Libraries(2020)10.17615/34fj-dp19

N/A

0DataRank · unranked

0 citations

Gurkan Guntas, Tishan Williams, Ryan A. Hallett, James E. Bear, Hayretin Yumerefendi +2 more

Computer-Based Redesign of a β Sandwich Protein Suggests that Extensive Negative Design Is Not Required for De Novo β Sheet Design

UNC Libraries(2020)10.17615/c6db-b739

N/A

0DataRank · unranked

0 citations

Xiaozhen Hu, Brian Kuhlman, Hengming Ke, Huanchen Wang

Incorporation of Noncanonical Amino Acids into Rosetta and Use in Computational Protein-Peptide Interface Design

UNC Libraries(2020)10.17615/0jkp-vh25

N/A

0DataRank · unranked

0 citations

Brian Kuhlman, Eun Jung Choi, P.D. Renfrew, Richard Bonneau

Strategies to control the binding mode of de novo designed protein interactions

UNC Libraries(2020)10.17615/a77n-4116

N/A

0DataRank · unranked

0 citations

Bryan S. Der, Brian Kuhlman

A structural bioinformatics approach for identifying proteins predisposed to bind linear epitopes on pre-selected target proteins

UNC Libraries(2020)10.17615/fcj3-1z75

N/A

0DataRank · unranked

0 citations

Eun Jung Choi, Brian Kuhlman, Ron Jacak

Anchored Design of Protein-Protein Interfaces

UNC Libraries(2020)10.17615/mvcb-xj28

N/A

0DataRank · unranked

0 citations

S. Mitchell Lewis, Brian Kuhlman

Increasing Sequence Diversity with Flexible Backbone Protein Design: The Complete Redesign of a Protein Hydrophobic Core

UNC Libraries(2020)10.17615/s08f-8683

N/A

0DataRank · unranked

0 citations

Mischa Machius, Jeffrey Mills, Thomas Szyperski, Michael J. Miley, Brian Kuhlman +1 more

Role of Electrostatic Repulsion in Controlling pH-Dependent Conformational Changes of Viral Fusion Proteins

UNC Libraries(2020)10.17615/wzdz-sn06

N/A

0DataRank · unranked

0 citations

Joseph S. Harrison, Jayne F. Koellhoffer, Jonathan R. Lai, Matthew J. O’Meara, Brian Kuhlman +1 more

Computational Design of the Sequence and Structure of a Protein-Binding Peptide

INDIGO (University of Illinois at Chicago)(2020)10.17615/jew7-ca23

N/A

0DataRank · unranked

0 citations

Deanne W. Sammond, Brian Kuhlman, David P. Siderovski, Glenn L. Butterfoss, Dustin E. Bosch +2 more

Lamellipodia are crucial for haptotactic sensing and response

UNC Libraries(2020)10.17615/wy7s-wc23

N/A

0DataRank · unranked

0 citations

Norman E. Sharpless, Alicia C. Tagliatela, James E. Bear, Seth P. Zimmerman, Jason M. Haugh +11 more

Light-induced nuclear export reveals rapid dynamics of epigenetic modifications

UNC Libraries(2020)10.17615/myp5-ws09

N/A

0DataRank · unranked

0 citations

James E. Bear, Klaus M. Hahn, Andrew M. Lerner, Seth P. Zimmerman, Brian D. Strahl +2 more

Ubiquitin-conjugating Enzyme Cdc34 and Ubiquitin Ligase Skp1-Cullin-F-box Ligase (SCF) Interact through Multiple Conformations

UNC Libraries(2020)10.17615/6agp-4071

N/A

0DataRank · unranked

0 citations

Amy Ziemba, Gary Kleiger, Brian Kuhlman, Steven L. Lewis, Daniella Sandoval +1 more

A comparison of successful and failed protein interface designs highlights the challenges of designing buried hydrogen bonds

UNC Libraries(2020)10.17615/wv99-pw07

N/A

0DataRank · unranked

0 citations

P. Benjamin Stranges, Brian Kuhlman

Tryptophanyl-tRNA Synthetase Urzyme: A MODEL TO RECAPITULATE MOLECULAR EVOLUTION AND INVESTIGATE INTRAMOLECULAR COMPLEMENTATION

UNC Libraries(2020)10.17615/2zwr-1s12

N/A

0DataRank · unranked

0 citations

Violetta Weinreb, Hao Hu, Brian Kuhlman, Yen Pham, Glenn L. Butterfoss +1 more

A biosensor generated via high-throughput screening quantifies cell edge Src dynamics

UNC Libraries(2020)10.17615/tbwp-gq85

N/A

0DataRank · unranked

0 citations

Eric A. Vitriol, Akash Gulyani, Dmitriy Gremyachinskiy, Tim Elston, Jianrong Wu +7 more

Probing the minimal determinants of zinc binding with computational protein design

UNC Libraries(2020)10.17615/j0mp-5z59

N/A

0DataRank · unranked

0 citations

Brian Kuhlman, Bryan S. Der, Sharon L. Guffy

Engineering a genetically encoded competitive inhibitor of the KEAP1–NRF2 interaction via structure-based design and phage display

UNC Libraries(2020)10.17615/m47n-hk89

N/A

0DataRank · unranked

0 citations

Gurkan Guntas, Brian Kuhlman, Thomas R. Lane, Ashutosh Tripathy, Kathleen M. Mulvaney +3 more

Ensuring scientific reproducibility in bio-macromolecular modeling via extensive, automated benchmarks

Nature Communications(2021)10.1038/s41467-021-27222-7

N/A

0DataRank · unranked

27 citations

Sergey Lyskov, Steven M. Lewis, Jared Adolf‐Bryfogle, Rebecca F. Alford, Kyle A. Barlow +45 more

Biophysical and Structural Characterization of Novel RAS-Binding Domains (RBDs) of PI3Kα and PI3Kγ

Journal of Molecular Biology(2021)10.1016/j.jmb.2021.166838

N/A

0DataRank · unranked

11 citations

David F. Thieker, Leiah M. Carey, Juhi A. Rasquinha, Samantha Kistler, Brian Kuhlman +2 more

Designer proteins that competitively inhibit Gαq by targeting its effector site

Journal of Biological Chemistry(2021)10.1016/j.jbc.2021.101348

N/A

0DataRank · unranked

10 citations

Matthew C. Cummins, Stuart Endo-Streeter, John Sondek, Brian Kuhlman, Mahmud M. Hussain

Ensuring scientific reproducibility in bio-macromolecular modeling via extensive, automated benchmarks

bioRxiv (Cold Spring Harbor Laboratory)(2021)10.1101/2021.04.04.438423

N/A

0DataRank · unranked

4 citations

Sergey Lyskov, Steven M. Lewis, Jared Adolf‐Bryfogle, Rebecca F. Alford, Kyle A. Barlow +43 more

Labelling and optical erasure of synaptic memory traces in the motor cortex

UNC Libraries(2021)10.17615/h8tm-ww07

N/A

0DataRank · unranked

0 citations

Fukutoshi Shirai, Amanda L. Loshbaugh, Mayumi Nakamura, Sho Yagishita, Brian Kuhlman +4 more

Minimal Determinants for Binding Activated Gα from the Structure of a Gα i1 −Peptide Dimer † , ‡

UNC Libraries(2021)10.17615/qech-wh86

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0DataRank · unranked

0 citations

Екатерина С. Лобанова, Francis S. Willard, Zoey L. Fredericks, Alexander S. Shavkunov, Christopher O. Johnston +6 more

High-resolution Structural and Thermodynamic Analysis of Extreme Stabilization of Human Procarboxypeptidase by Computational Protein Design

UNC Libraries(2021)10.17615/z2r0-qc76

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0DataRank · unranked

0 citations

Ziad M. Eletr, Gautam Dantas, James J. Havranek, E.A. Merritt, Gabriele Varani +5 more

Advances in modular control of CAR-T therapy with adapter-mediated CARs

Advanced Drug Delivery Reviews(2022)10.1016/j.addr.2022.114358

N/A

0DataRank · unranked

31 citations

Zhiyuan Yao, Brian Kuhlman, Amelia C. McCue

A conserved set of mutations for stabilizing soluble envelope protein dimers from dengue and Zika viruses to advance the development of subunit vaccines

Journal of Biological Chemistry(2022)10.1016/j.jbc.2022.102079

N/A

0DataRank · unranked

26 citations

Matthew G. Hvasta, Stephan T. Kudlacek, Devina Thiono, Ashutosh Tripathy, Nathan I. Nicely +3 more

Designer installation of a substrate recruitment domain to tailor enzyme specificity

Nature Chemical Biology(2022)10.1038/s41589-022-01206-0

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0DataRank · unranked

17 citations

Chayanid Ongpipattanakul, Satish K. Nair, Albert A. Bowers, Brian Kuhlman, Rodney Park

AlphaFold accurately predicts distinct conformations based on the oligomeric state of a de novo designed protein

Protein Science(2022)10.1002/pro.4368

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0DataRank · unranked

14 citations

Timothy M. Jacobs, Frank D. Teets, Frank DiMaio, Ashutosh Tripathy, Brian Kuhlman +1 more

From Protein Design to the Energy Landscape of a Cold Unfolding Protein

The Journal of Physical Chemistry B(2022)10.1021/acs.jpcb.1c10750

N/A

0DataRank · unranked

9 citations

Jack B. Maguire, Shirley Yuen, Joseph S. Harrison, Jermel R. Griffin, Lakshmanane Premkumar +8 more

AlphaFold accurately predicts distinct conformations based on oligomeric state of a de novo designed protein

bioRxiv (Cold Spring Harbor Laboratory)(2022)10.1101/2022.02.02.478886

N/A

0DataRank · unranked

1 citations

Timothy M. Jacobs, Frank D. Teets, Frank DiMaio, Ashutosh Tripathy, Brian Kuhlman +1 more

In silico evolution of autoinhibitory domains for a PD-L1 antagonist using deep learning models

Proceedings of the National Academy of Sciences(2023)10.1073/pnas.2307371120

N/A

0DataRank · unranked

50 citations

Amrita Nallathambi, Tomoaki Kinjo, Nicholas Z. Randolph, Brian Kuhlman, Odessa J. Goudy

Design of a protease‐activated PD‐L1 inhibitor

Protein Science(2023)10.1002/pro.4578

N/A

0DataRank · unranked

5 citations

Alice Peng, Ashutosh Tripathy, Brian Kuhlman, Odessa J. Goudy

Transfer learning to leverage larger datasets for improved prediction of protein stability changes

bioRxiv (Cold Spring Harbor Laboratory)(2023)10.1101/2023.07.27.550881

N/A

0DataRank · unranked

19 citations

Michael Brocidiacono, Nicholas Z. Randolph, Brian Kuhlman, Henry Dieckhaus

In silico evolution of protein binders with deep learning models for structure prediction and sequence design

bioRxiv (Cold Spring Harbor Laboratory)(2023)10.1101/2023.05.03.539278

N/A

0DataRank · unranked

7 citations

Amrita Nallathambi, Tomoaki Kinjo, Nicholas Z. Randolph, Brian Kuhlman, Odessa J. Goudy

Invariant point message passing for protein side chain packing

bioRxiv (Cold Spring Harbor Laboratory)(2023)10.1101/2023.08.03.551328

N/A

0DataRank · unranked

2 citations

Brian Kuhlman, Nicholas Z. Randolph

De novo design of stable proteins that efficaciously inhibit oncogenic G proteins

bioRxiv (Cold Spring Harbor Laboratory)(2023)10.1101/2023.03.28.534629

N/A

0DataRank · unranked

0 citations

Ashutosh Tripathy, John Sondek, Brian Kuhlman, Matthew C. Cummins

Data from Modifications to the Framework Regions Eliminate Chimeric Antigen Receptor Tonic Signaling

(2023)10.1158/2326-6066.c.6550485

N/A

0DataRank · unranked

0 citations

Giovanni Fucà, Jian Wang, Venkat R. Chirasani, Zhiyuan Yao, Elena Dukhovlinova +14 more

Protein stability models fail to capture epistatic interactions of double point mutations

Protein Science(2024)10.1002/pro.70003

N/A

0DataRank · unranked

15 citations

Brian Kuhlman, Henry Dieckhaus

Invariant point message passing for protein side chain packing

Proteins Structure Function and Bioinformatics(2024)10.1002/prot.26705

N/A

0DataRank · unranked

10 citations

Brian Kuhlman, Nicholas Z. Randolph

High-resolution epitope mapping of commercial antibodies to ANCA antigens by yeast surface display

Journal of Immunological Methods(2024)10.1016/j.jim.2024.113654

N/A

0DataRank · unranked

5 citations

Sajan A. Lamba, Meghan E. Free, Gang Xi, Elizabeth A. McInnis, Gabrielle Williams +5 more

Protein stability models fail to capture epistatic interactions of double point mutations

bioRxiv (Cold Spring Harbor Laboratory)(2024)10.1101/2024.08.20.608844

N/A

0DataRank · unranked

6 citations

Brian Kuhlman, Henry Dieckhaus

WITHDRAWN: Structural Enzymology, Phylogenetics, Differentiation, and Symbolic Reflexivity at the Dawn of Biology

bioRxiv (Cold Spring Harbor Laboratory)(2024)10.1101/2024.12.17.628912

N/A

0DataRank · unranked

1 citations

Guo Qing Tang, Sourav Kumar Patra, Laurie Betts, Henry Dieckhaus, Brian Kuhlman +6 more

An optogenetic switch for the Set2 methyltransferase provides evidence for transcription-dependent and -independent dynamics of H3K36 methylation

UNC Libraries(2024)10.17615/qpkr-t108

N/A

0DataRank · unranked

0 citations

Austin J. Hepperla, Seth P. Zimmerman, Gregory R. Keele, Ian J. Davis, Brian Kuhlman +6 more

Engineering Improved Photoswitches for the Control of Nucleocytoplasmic Distribution

Figshare(2024)10.17615/pe0y-6265

N/A

0DataRank · unranked

0 citations

Hayretin Yumerefendi, Brian D. Strahl, Andrew M. Lerner, Brian Kuhlman, Odessa J. Goudy

Designer proteins that competitively inhibit Gαq by targeting its effector site

UNC Libraries(2024)10.17615/097x-ky07

N/A

0DataRank · unranked

0 citations

Stuart Endo-Streeter, John Sondek, Mahmud M. Hussain, Matthew C. Cummins, Brian Kuhlman

Biophysical and Structural Characterization of Novel RAS-Binding Domains (RBDs) of PI3Kα and PI3Kγ

UNC Libraries(2024)10.17615/bz1y-1w52

N/A

0DataRank · unranked

0 citations

Samantha Kistler, Nicholas Martinez, David F. Thieker, Sharon L. Campbell, Leiah M. Carey +2 more

Engineering a tumor-selective prodrug T-cell engager bispecific antibody for safer immunotherapy

UNC Libraries(2024)10.17615/dpdp-mk82

N/A

0DataRank · unranked

0 citations

Brian Kuhlman, Amelia C. McCue, Karen Froning, Stephen J. Demarest, Michael J. Hickey +1 more

Design of a Water-Soluble CD20 Antigen with Computational Epitope Scaffolding

bioRxiv (Cold Spring Harbor Laboratory)(2024)10.1101/2024.12.05.627087

N/A

0DataRank · unranked

0 citations

Brian Kuhlman, Zhiyuan Yao

Structural Enzymology, Phylogenetics, Differentiation, and Symbolic Reflexivity at the Dawn of Biology

Genome Biology and Evolution(2025)10.1093/gbe/evaf095

N/A

0DataRank · unranked

3 citations

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ACS Chemical Biology(2025)10.1021/acschembio.5c00253

N/A

0DataRank · unranked

3 citations

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Protein Science(2025)10.1002/pro.70184

N/A

0DataRank · unranked

2 citations

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Structural Dynamics(2025)10.1063/4.0000294

N/A

0DataRank · unranked

2 citations

Nicholas Z. Randolph, Brian Kuhlman, Henry Dieckhaus, Laurie Betts, Jordan Douglas +3 more

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bioRxiv (Cold Spring Harbor Laboratory)(2025)10.1101/2025.10.27.684804

N/A

0DataRank · unranked

0 citations

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Rosetta3: An Object-Oriented Software Suite for the Simulation and Design of Macromolecules

UNC Libraries(2020)10.17615/8ga2-9t05

N/A

0DataRank · unranked

149 citations

Monica Berrondo, Andrew Leaver-Fay, James Thompson, S. I. Cooper, Daniel J. Mandell +27 more

Dimerization of Dengue Virus E Subunits Impacts Antibody Function and Domain Focus

Journal of Virology(2020)10.1128/jvi.00745-20

N/A

0DataRank · unranked

20 citations

Devina Thiono, Stephan T. Kudlacek, J.-G. Forsberg, Lakshmanane Premkumar, Shaomin Tian +4 more

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PLoS Computational Biology(2020)10.1371/journal.pcbi.1007507

N/A

0DataRank · unranked

44 citations

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UNC Libraries(2020)10.17615/ktmy-3f93

N/A

0DataRank · unranked

2 citations

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