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Designer proteins that competitively inhibit Gαq by targeting its effector site

UNC Libraries(2024)10.17615/097x-ky07Source: DataRank Database

Designer proteins that competitively inhibit Gαq by targeting its effector site is a research paper published in UNC Libraries (2024). On theSindex it has a DataRank of 0.

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Open Access0 citations

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›Methodology & internals

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Pipeline:MetadataData-paper checkEnrichmentCitation networkScoring

Enrichment:Funding (4 grants)Impact (FWCI 0.00)OA: greenTopics (23)IDs (PubMed, OpenAlex)SDGs (1)

FAIR Checklist

Context only (not used in score)

Findable (1/2)

Has DOI

Accessible (1/2)

Open Access

Interoperable (0/2)

Reusable (0/3)

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Authors (5)

Stuart Endo-Streeter,John Sondek ORCID,Mahmud M. Hussain,Matthew C. Cummins ORCID,Brian Kuhlman ORCID

Live enrichment

PubMed:21097893 OpenAlex:https://openalex.org/W4401040710

National Institutes of Health

Grant: 3R01GM057391-19S1

Regulation of phospholipase C

National Institutes of Health

Grant: 5T32GM007040-35

Predoctoral Training in Pharmacological Sciences

National Institutes of Health

Grant: 5R01GM120291-04

Inhibition of GTPases and G proteins to treat human disease

National Institutes of Health

Grant: 5R35GM131923-02

Computational Design of Protein Structures and Complexes

FWCI

0.00

Citation Percentile

0.2%

greenLicense: CC BY

repositoryhttps://doi.org/10.17615/097x-ky07

https://doi.org/10.1016/j.jbc.2021.101348

http://www.jbc.org/article/S0021925821011546/pdf

https://dx.doi.org/10.17615/097x-ky07

https://pubmed.ncbi.nlm.nih.gov/34715131

Fields of Study

Pancreatic function and diabetesSignaling Pathways in Disease0301 basic medicine0303 health sciences03 medical and health sciences

Keywords

EffectorChemistryCell biologyComputational biologyBiologyModels, MolecularPhospholipase C betaProtein EngineeringRecombinant ProteinsHEK293 CellsDrug DesignGTP-Binding Protein alpha Subunits, Gq-G11HumansCloning, MolecularDatabases, ProteinPeptidesResearch ArticleProtein Binding

Sustainable Development Goals

SDG 0: Zero hunger