Björn C. Knollmann

MedicineBiochemistry, Genetics and Molecular Biology

Pilot corpus only

This score is computed over theSindex pilot corpus and does not cover the full scientific literature. Scores are relative to papers we have ingested — papers, authors, and institutions outside the pilot are not represented. Methodology.

Top 100%percentile

0Author DataRank

Indexed papers

0in pilot corpus

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Papers

Driven by 49 papers. Top paper: “A Genetic Mouse Model Recapitulates Immune Checkpoint Inhibitor–Associated Myocarditis and Supports a Mechanism-Based Therapeutic Intervention”.

A Genetic Mouse Model Recapitulates Immune Checkpoint Inhibitor–Associated Myocarditis and Supports a Mechanism-Based Therapeutic Intervention

Cancer Discovery(2020)10.1158/2159-8290.cd-20-0856

N/A

8.5DataRank · unranked

279 citations

Wouter C. Meijers, Margaret L. Axelrod, Nana-Ama A.S. Anang, Elles M. Screever, Elizabeth C. Wescott +22 more

Atropine-induced sinus tachycardia protects against exercise-induced ventricular arrhythmias in patients with catecholaminergic polymorphic ventricular tachycardia

EP Europace(2020)10.1093/europace/euaa029

N/A

0.826DataRank · unranked

18 citations

M. Benjamin Shoemaker, Kathryn A. Gayle, Darlene Fountain, Dan M. Roden, Björn C. Knollmann +1 more

Exercise Causes Arrhythmogenic Remodeling of Intracellular Calcium Dynamics in Plakophilin-2–Deficient Hearts

Circulation(2022)10.1161/circulationaha.121.057757

N/A

0.621DataRank · unranked

62 citations

Navratan Bagwan, Svetlana Maurya, Joon-Chul Kim, Abigail N. Smith, Daniel J. Blackwell +6 more

Multiplexed Assays of Variant Effect and Automated Patch Clamping Improve KCNH2 -LQTS Variant Classification and Cardiac Event Risk Stratification

Circulation(2024)10.1161/circulationaha.124.069828

N/A

0.553DataRank · unranked

39 citations

Chai‐Ann Ng, Takanori Aizawa, Luca Sala, Sahej Bains, Annika Winbo +37 more

Transcriptional Dysregulation Underlies Both Monogenic Arrhythmia Syndrome and Common Modifiers of Cardiac Repolarization

Circulation(2022)10.1161/circulationaha.122.062193

N/A

0.510DataRank · unranked

29 citations

Tao Yang, Jonathan D. Mosley, Andrew M. Glazer, Andrew T. Hale, Dmytro O. Kryshtal +29 more

Different arrhythmia-associated calmodulin mutations have distinct effects on cardiac SK channel regulation

The Journal of General Physiology(2020)10.1085/jgp.202012667

N/A

0.442DataRank · unranked

18 citations

Seojin Park, Duncan F. Muir, Ryan L. Woltz, Lu Ren, Phuong T. Nguyen +10 more

In Vivo Pharmacokinetic and Pharmacodynamic Properties of the Antiarrhythmic Molecule ent-Verticilide

Journal of Pharmacology and Experimental Therapeutics(2023)10.1124/jpet.122.001455

N/A

0.396DataRank · unranked

13 citations

Abigail N. Smith, Tri Q., Aaron Gochman, Jeffrey Schmeckpeper, Corey R. Hopkins +4 more

Ryanodine receptor 2 inhibition reduces dispersion of cardiac repolarization, improves contractile function, and prevents sudden arrhythmic death in failing hearts

eLife(2023)10.7554/elife.88638

N/A

0.360DataRank · unranked

10 citations

Shanea Estes, Deeptankar DeMazumder, Björn C. Knollmann, Swati Dey, Pooja Joshi

Pharmacologic Therapy for Engraftment Arrhythmia Induced by Transplantation of Human Cardiomyocytes

bioRxiv (Cold Spring Harbor Laboratory)(2021)10.1101/2021.02.15.431108

N/A

0.345DataRank · unranked

9 citations

Lauren E. Neidig, Xiulan Yang, Gerhard Weber, Danny El‐Nachef, Hiroshi Tsuchida +18 more

A high-performance extracellular field potential analyzer for iPSC-derived cardiomyocytes

Scientific Reports(2025)10.1038/s41598-025-88946-w

N/A

0.241DataRank · unranked

4 citations

Alex Shen, Yuko Wada, Marcia Blair, Devyn Mitchell, Loren Vanags +10 more

Ryanodine Receptor Inhibition with Dantrolene Prevents Ventricular Tachycardia Induction in Patients with Structural Heart Disease – A Randomized Controlled Trial

medRxiv(2025)10.1101/2025.08.17.25333868

N/A

0.107DataRank · unranked

1 citations

Zachary T. Yoneda, Bibin Varghese, Dakota Grauherr, Diane M. Crawford, Jeffrey Schmeckpeper +17 more

RyR2 inhibition with dantrolene is antiarrhythmic, antifibrotic, and improves cardiac function in chronic ischemic heart disease

bioRxiv (Cold Spring Harbor Laboratory)(2022)10.1101/2022.06.24.496861

N/A

0.104DataRank · unranked

1 citations

KyungSoo Kim, Sharon A. George, Dan Blackwell, Jaclyn A. Brennan, Igor R. Efimov +2 more

Autosomal-Dominant CASQ2-K180R Causes CPVT by Altering Intra-SR Calcium Buffering without Reducing Casq2 Protein Levels

Biophysical Journal(2021)10.1016/j.bpj.2020.11.1572

N/A

0.104DataRank · unranked

1 citations

Shan Parikh, Daniel J. Blackwell, Björn C. Knollmann, Matthew J. Wleklinski

Multiplexed Assays of Variant Effect and Automated Patch-clamping Improve KCNH2 -LQTS Variant Classification and Cardiac Event Risk Stratification

medRxiv(2024)10.1101/2024.02.01.24301443

N/A

0.104DataRank · unranked

1 citations

Chai‐Ann Ng, Takanori Aizawa, Luca Sala, Sahej Bains, Annika Winbo +37 more

The selective RyR2 inhibitor ent-verticilide suppresses atrial fibrillation susceptibility caused by Pitx2 deficiency

Journal of Molecular and Cellular Cardiology(2023)10.1016/j.yjmcc.2023.04.005

N/A

0DataRank · unranked

32 citations

Daniel J. Blackwell, Samantha L. Yuen, Madelaine P. Thorpe, Jeffrey N. Johnston, Rǎzvan L. Cornea +2 more

Cardiac troponin T N-domain variant destabilizes the actin interface resulting in disturbed myofilament function

Proceedings of the National Academy of Sciences(2023)10.1073/pnas.2221244120

N/A

0DataRank · unranked

27 citations

Weikang Ma, Taejeong Song, Hosna Rastegarpouyani, Henry Gong, Isabella Leite Coscarella +12 more

RyR2 inhibition with dantrolene is antiarrhythmic, prevents further pathological remodeling, and improves cardiac function in chronic ischemic heart disease

Journal of Molecular and Cellular Cardiology(2023)10.1016/j.yjmcc.2023.05.009

N/A

0DataRank · unranked

23 citations

KyungSoo Kim, Sharon A. George, Daniel J. Blackwell, Jaclyn A. Brennan, Igor R. Efimov +2 more

Eicosanoid-Regulated Myeloid ENaC and Isolevuglandin Formation in Human Salt-Sensitive Hypertension

Hypertension(2023)10.1161/hypertensionaha.123.21285

N/A

0DataRank · unranked

22 citations

Ashley Pitzer Mutchler, Sydney Jamison, Cheryl L. Laffer, Fernando Elijovich, Mohammad Saleem +14 more

Studying Long QT Syndrome Caused by NAA10 Genetic Variants Using Patient-Derived Induced Pluripotent Stem Cells

Circulation(2023)10.1161/circulationaha.122.061864

N/A

0DataRank · unranked

16 citations

Yiyang Wu, Mengcheng Shen, Sophia Zhang, Joe Z. Zhang, Chun Liu +5 more

Cellular and electrophysiological characterization of triadin knockout syndrome using induced pluripotent stem cell-derived cardiomyocytes

Stem Cell Reports(2023)10.1016/j.stemcr.2023.04.005

N/A

0DataRank · unranked

12 citations

Dan Ye, Lili Wang, C.S. John Kim, Wei Zhou, Steven M. Dotzler +5 more

Disruption of Z-Disc Function Promotes Mechanical Dysfunction in Human Myocardium: Evidence for a Dual Myofilament Modulatory Role by Alpha-Actinin 2

International Journal of Molecular Sciences(2023)10.3390/ijms241914572

N/A

0DataRank · unranked

11 citations

Jeffrey Schmeckpeper, Maicon Landim-Vieira, Isabella Leite Coscarella, Xuan Fang, Weikang Ma +12 more

Genetic Inhibition of Mitochondrial Permeability Transition Pore Exacerbates Ryanodine Receptor 2 Dysfunction in Arrhythmic Disease

Cells(2023)10.3390/cells12020204

N/A

0DataRank · unranked

8 citations

Brian D. Tow, You Qing, Madelyn Walker, Emmanuel R. Hodges, James A. Stewart +5 more

RyR2 Binding of an Antiarrhythmic Cyclic Depsipeptide Mapped Using Confocal Fluorescence Lifetime Detection of FRET

ACS Chemical Biology(2023)10.1021/acschembio.3c00376

N/A

0DataRank · unranked

6 citations

Jacob Schwarz, Abigail N. Smith, Bengt Svensson, Daniel J. Blackwell, Taylor A. Phillips +11 more

ent -Verticilide B1 inhibits type 2 ryanodine receptor channels and is antiarrhythmic in Casq2-/- mice

bioRxiv (Cold Spring Harbor Laboratory)(2023)10.1101/2023.07.03.547578

N/A

0DataRank · unranked

3 citations

Tri Q., Kyung‐Soo Kim, Jacob Schwarz, Madelaine P. Thorpe, Daniel J. Blackwell +7 more

RyR2 Binding of an Antiarrhythmic Cyclic Depsipeptide Mapped Using Confocal Fluorescence Lifetime Detection of FRET

bioRxiv (Cold Spring Harbor Laboratory)(2023)10.1101/2023.06.22.546083

N/A

0DataRank · unranked

0 citations

Jacob Schwarz, Abigail N. Smith, Bengt Svensson, Daniel J. Blackwell, Taylor A. Phillips +11 more

Ryanodine receptor 2 inhibition reduces dispersion of cardiac repolarization, improves contractile function, and prevents sudden arrhythmic death in failing hearts

eLife(2023)10.7554/elife.88638.3

N/A

0DataRank · unranked

0 citations

Shanea Estes, Deeptankar DeMazumder, Björn C. Knollmann, Swati Dey, Pooja Joshi

The backbone constitution drives passive permeability independent of side chains in depsipeptide and peptide macrocycles inspired by ent -verticilide

Chemical Science(2024)10.1039/d4sc02758b

N/A

0DataRank · unranked

7 citations

Abigail N. Smith, Daniel J. Blackwell, Corey R. Hopkins, Björn C. Knollmann, Wendell S. Akers +2 more

The proteostasis interactomes of trafficking-deficient variants of the voltage-gated potassium channel KV11.1 associated with long QT syndrome

Journal of Biological Chemistry(2024)10.1016/j.jbc.2024.107465

N/A

0DataRank · unranked

5 citations

Lea A. Barny, Tri Q., Eli Fritz McDonald, Björn C. Knollmann, Lars Plate +1 more

Conditional ablation of MCU exacerbated cardiac pathology in a genetic arrhythmic model of CPVT

Journal of Molecular and Cellular Cardiology Plus(2024)10.1016/j.jmccpl.2024.100093

N/A

0DataRank · unranked

1 citations

Brian D. Tow, Jie Hao, Branden L. Nguyen, Valeria Gomez, James A. Stewart +5 more

The proteostasis interactomes of trafficking-deficient K V 11.1 variants associated with Long QT Syndrome and pharmacological chaperone rescue

bioRxiv (Cold Spring Harbor Laboratory)(2024)10.1101/2024.01.31.574410

N/A

0DataRank · unranked

0 citations

Lea A. Barny, Tri Q., Eli Fritz McDonald, Lars Plate, Björn C. Knollmann +1 more

Impaired Atrial Mitochondrial Calcium Handling in Patients With Atrial Fibrillation

Circulation Research(2025)10.1161/circresaha.124.325658

N/A

0DataRank · unranked

10 citations

Fleur E. Mason, Eva A. Rog‐Zielinska, Funsho E. Fakuade, Donata Bülow, Marcell Tóth +39 more

Cell painting based high-content phenotypic screening to elucidate kinase signaling pathways in ibrutinib-mediated atrial fibrillation

European Heart Journal Supplements(2025)10.1093/eurheartjsupp/suaf083.224

N/A

0DataRank · unranked

0 citations

Christian Egly, Marcia Blair, Thomas P. Hasaka, J A Bauer, Björn C. Knollmann +2 more

High-throughput screens identify genotype-specific therapeutics for channelopathies

JCI Insight(2025)10.1172/jci.insight.191697

N/A

0DataRank · unranked

0 citations

Alex Shen, Tri Q., Carlos Tellet Cabiya, Paxton A. Ritschel, Suah Woo +5 more

Introduction of a single carboxylic acid converts the cyclic oligomeric depsipeptide ent-verticilide from a ryanodine receptor 2 (RyR2) inhibitor to RyR2 activator

Molecular Pharmacology(2025)10.1016/j.molpha.2025.100086

N/A

0DataRank · unranked

0 citations

Daniel J. Blackwell, Abigail N. Smith, Madelaine P. Thorpe, Robyn T. Rebbeck, Derek R. Laver +3 more

Cardiomyocyte Nuclear Pleomorphism in a Mouse Model of Inherited Hypertrophic Cardiomyopathy

Journal of Cardiovascular Development and Disease(2025)10.3390/jcdd12110449

N/A

0DataRank · unranked

0 citations

Isabella Leite Coscarella, C. Sainte Rose, Yun Shi, Hosna Rastegarpouyani, Karissa M. Dieseldorff Jones +14 more

Mapping the Functional Landscape of KCNQ1 to Define Ion Channel Mechanisms and Arrhythmia Risk

medRxiv(2025)10.64898/2025.12.15.25341924

N/A

0DataRank · unranked

0 citations

Ellen M Osborn, Megan Lancaster, Joseh J. Smith, Qianyi Shen, Temidayo Abe +24 more

Increased RyR2 activity is exacerbated by calcium leak-induced mitochondrial ROS

Basic Research in Cardiology(2020)10.1007/s00395-020-0797-z

N/A

0DataRank · unranked

120 citations

Radmila Terentyeva, Benjamin Martin, Fruzsina Perger, Jiaoni Li, Stepanov Av +7 more

MCL-1 Inhibition by Selective BH3 Mimetics Disrupts Mitochondrial Dynamics Causing Loss of Viability and Functionality of Human Cardiomyocytes

iScience(2020)10.1016/j.isci.2020.101015

N/A

0DataRank · unranked

91 citations

Nilay Taneja, Abigail C. Neininger, Lili Wang, Gabriella L. Robertson, Stellan Riffle +5 more

High-throughput discovery of trafficking-deficient variants in the cardiac potassium channel KV11.1

Heart Rhythm(2020)10.1016/j.hrthm.2020.05.041

N/A

0DataRank · unranked

66 citations

Andrew M. Glazer, Chai‐Ann Ng, Daniel J. Blackwell, Christian Egly, Loren Vanags +9 more

Conditional Up-Regulation of SERCA2a Exacerbates RyR2-Dependent Ventricular and Atrial Arrhythmias

International Journal of Molecular Sciences(2020)10.3390/ijms21072535

N/A

0DataRank · unranked

18 citations

Qing Lou, Heather N. Smith, Florencia Velez‐Cortes, Wolfgang Dillmann, Björn C. Knollmann +3 more

Pharmacologic therapy for engraftment arrhythmia induced by transplantation of human cardiomyocytes

Stem Cell Reports(2021)10.1016/j.stemcr.2021.08.005

N/A

0DataRank · unranked

85 citations

Lauren E. Neidig, Xiulan Yang, Gerhard Weber, Danny El‐Nachef, Hiroshi Tsuchida +19 more

Triiodothyronine and dexamethasone alter potassium channel expression and promote electrophysiological maturation of human-induced pluripotent stem cell-derived cardiomyocytes

Journal of Molecular and Cellular Cardiology(2021)10.1016/j.yjmcc.2021.08.005

N/A

0DataRank · unranked

38 citations

Yuko Wada, Nimer Ballan, Jeffrey Schmeckpeper, Jijun Huang, Christoph Rau +4 more

Assessment of dynamic cardiac repolarization and contractility in patients with hypertrophic cardiomyopathy

PLoS ONE(2021)10.1371/journal.pone.0246768

N/A

0DataRank · unranked

0 citations

Lucy Y. Lei, Sachin Y. Paranjape, Daniel J. Blackwell, Robert L. Abraham, Derek S. Chew +3 more

Animal Models to Study Cardiac Arrhythmias

Circulation Research(2022)10.1161/circresaha.122.320258

N/A

0DataRank · unranked

84 citations

Jeffrey Schmeckpeper, Björn C. Knollmann, Daniel J. Blackwell

Guidelines for assessment of cardiac electrophysiology and arrhythmias in small animals

American Journal of Physiology-Heart and Circulatory Physiology(2022)10.1152/ajpheart.00439.2022

N/A

0DataRank · unranked

62 citations

Alexey V. Glukhov, Matthew W. Kay, Bastiaan J. Boukens, Nipavan Chiamvimonvat, Brian P. Delisle +12 more

The Purkinje–myocardial junction is the anatomic origin of ventricular arrhythmia in CPVT

JCI Insight(2022)10.1172/jci.insight.151893

N/A

0DataRank · unranked

33 citations

Michela Faggioni, Matthew J. Wleklinski, Nieves Gómez‐Hurtado, Raghav Venkataraman, Chelsea E. Gibbs +7 more

A High-Throughput Screening Assay to Identify Drugs that Can Treat Long QT Syndrome Caused by Trafficking-Deficient KV11.1 (hERG) Variants

Molecular Pharmacology(2022)10.1124/molpharm.121.000421

N/A

0DataRank · unranked

8 citations

Daniel J. Blackwell, Jeffrey Schmeckpeper, Brian P. Delisle, C. David Weaver, Björn C. Knollmann +1 more

Low expression of the K280N TNNT2 mutation is sufficient to increase basal myofilament activation in human hypertrophy cardiomyopathy

Journal of Molecular and Cellular Cardiology Plus(2022)10.1016/j.jmccpl.2022.100007

N/A

0DataRank · unranked

5 citations

Lili Wang, Paul J.M. Wijnker, KyungSoo Kim, José R. Pinto, Cristobal Dos Remedios +4 more

Gene editing to prevent ventricular arrhythmias associated with cardiomyocyte cell therapy

Cell stem cell(2023)10.1016/j.stem.2023.03.010

N/A

0DataRank · unranked

84 citations

Kenta Nakamura, Hans Reinecke, Lauren E. Neidig, Michael S. Lai, Shin Kadota +25 more