P. Loppnau

Also affiliated with Health Net

Biochemistry, Genetics and Molecular BiologyMedicine

Pilot corpus only

This score is computed over theSindex pilot corpus and does not cover the full scientific literature. Scores are relative to papers we have ingested — papers, authors, and institutions outside the pilot are not represented. Methodology.

Top 100%percentile

0Author DataRank

Indexed papers

1in pilot corpus

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Why this DataRank?

An author's DataRank is the sum of the DataRanks of all 1 indexed paper attributed to them. A prolific author with many moderate-impact papers can outrank one with a single high-impact paper.

Author scores recompute whenever paper DataRanks are refreshed, so this number lags the underlying paper scores by at most one batch run.

Read the full methodology →

The highest-impact dataset this researcher has shared, ranked by DataRank — the single contribution doing the most to lift their data-sharing standing.

A resource to enable chemical biology and drug discovery of WDR Proteins

bioRxiv (Cold Spring Harbor Laboratory)(2024)10.1101/2024.03.03.583197

Top 100%

0DataRank

Top 100%0 citations

Fengling Li, Magda Szewczyk, Almagul Seitova, P. Loppnau, Hong Zeng +65 more

Papers

Driven by 24 papers — median percentile 0. Top paper: “CACHE Challenge #2: Targeting the RNA Site of the SARS-CoV-2 Helicase Nsp13”.

CACHE Challenge #2: Targeting the RNA Site of the SARS-CoV-2 Helicase Nsp13

Journal of Chemical Information and Modeling(2025)10.1021/acs.jcim.5c00535

N/A

0.292DataRank · unranked

6 citations

Madhushika Silva, Ayaz Ahmad, Oscar E. A. Arce, Roly J. Armstrong, Cheryl Arrowsmith +105 more

CACHE Challenge #2: Targeting the RNA Site of the SARS-CoV-2 Helicase Nsp13

ChemRxiv(2025)10.26434/chemrxiv-2025-8f0rq-v3

N/A

0.165DataRank · unranked

2 citations

Madhushika Silva, Abd Al‐Aziz A. Abu‐Saleh, Ayaz Ahmad, Jesus Antonio Alvarado-Huayhuaz, Oscar E. A. Arce +104 more

CACHE Challenge #2: Targeting the RNA Site of the SARS-CoV-2 Helicase Nsp13

ChemRxiv(2025)10.26434/chemrxiv-2025-8f0rq

N/A

0.150DataRank · unranked

1 citations

Madhushika Silva, Abd Al‐Aziz A. Abu‐Saleh, Ayaz Ahmad, Jesus Antonio Alvarado-Huayhuaz, Oscar E. A. Arce +104 more

Probing the SAM Binding Site of SARS-CoV-2 Nsp14 In Vitro Using SAM Competitive Inhibitors Guides Developing Selective Bisubstrate Inhibitors

SLAS DISCOVERY(2021)10.1177/24725552211026261

N/A

0DataRank · unranked

89 citations

Matthieu Schapira, Sumera Perveen, Aliakbar Khalili Yazdi, Fengling Li, Irene Chau +15 more

Huntingtin structure is orchestrated by HAP40 and shows a polyglutamine expansion-specific interaction with exon 1

Communications Biology(2021)10.1038/s42003-021-02895-4

N/A

0DataRank · unranked

59 citations

Justin C. Deme, Johannes F. Hevler, Sem Tamara, Alexander Lemak, Jeffrey P. Cantle +15 more

Probing the SAM Binding Site of SARS-CoV-2 nsp14 in vitro Using SAM Competitive Inhibitors Guides Developing Selective bi-substrate Inhibitors

bioRxiv (Cold Spring Harbor Laboratory)(2021)10.1101/2021.02.19.424337

N/A

0DataRank · unranked

11 citations

Matthieu Schapira, Sumera Perveen, Aliakbar Khalili Yazdi, Fengling Li, Irene Chau +15 more

HAP40 orchestrates huntingtin structure for differential interaction with polyglutamine expanded exon 1

bioRxiv (Cold Spring Harbor Laboratory)(2021)10.1101/2021.04.02.438217

N/A

0DataRank · unranked

3 citations

Justin C. Deme, Johannes F. Hevler, Sem Tamara, Alexander Lemak, Jeffrey P. Cantle +12 more

A small molecule antagonist of SMN disrupts the interaction between SMN and RNAP II

Nature Communications(2022)10.1038/s41467-022-33229-5

N/A

0DataRank · unranked

20 citations

Aman Iqbal, Weiguo Li, Zuyao Ni, Yalong Wang, Jurupula Ramprasad +16 more

Expanding the Huntington’s disease research toolbox; validated subdomain protein constructs for biochemical and structural investigation of huntingtin

bioRxiv (Cold Spring Harbor Laboratory)(2022)10.1101/2022.11.21.516512

N/A

0DataRank · unranked

1 citations

Justin C. Deme, Claudia Alvarez, P. Loppnau, Ashley Hutchinson, Alma Seitova +9 more

Discovery of a First-in-Class Small-Molecule Ligand for WDR91 Using DNA-Encoded Chemical Library Selection Followed by Machine Learning

Journal of Medicinal Chemistry(2023)10.1021/acs.jmedchem.3c01471

N/A

0DataRank · unranked

18 citations

Jin Xu, Jianwen A. Feng, Ashley Hutchinson, Hong Zeng, Pegah Ghiabi +20 more

Delineation of functional subdomains of Huntingtin protein and their interaction with HAP40

Structure(2023)10.1016/j.str.2023.06.002

N/A

0DataRank · unranked

16 citations

Justin C. Deme, Claudia Alvarez, P. Loppnau, Ashley Hutchinson, Alma Seitova +9 more

Discovery of a first-in-class small molecule ligand for WDR91 using DNA-encoded chemical library selection followed by machine learning

bioRxiv (Cold Spring Harbor Laboratory)(2023)10.1101/2023.08.21.552681

N/A

0DataRank · unranked

2 citations

Jin Xu, Jianwen A. Feng, Ashley Hutchinson, Hong Zeng, Pegah Ghiabi +19 more

A Target Class Ligandability Evaluation of WD40 Repeat-Containing Proteins

Journal of Medicinal Chemistry(2024)10.1021/acs.jmedchem.4c02010

N/A

0DataRank · unranked

22 citations

Fengling Li, Magda Szewczyk, Almagul Seitova, P. Loppnau, Hong Zeng +67 more

Identification of Inhibitors of Chikungunya virus nsP2 ATPase

bioRxiv (Cold Spring Harbor Laboratory)(2024)10.1101/2024.12.02.625520

N/A

0DataRank · unranked

4 citations

J. E. Scott, Ginger R. Smith, Pegah Ghiabi, Elisa Gibson, P. Loppnau +8 more

A resource to enable chemical biology and drug discovery of WDR Proteins

bioRxiv (Cold Spring Harbor Laboratory)(2024)10.1101/2024.03.03.583197

Top 100%

0DataRank

Top 100%0 citations

Fengling Li, Magda Szewczyk, Almagul Seitova, P. Loppnau, Hong Zeng +65 more

Identification of Direct-Acting nsP2 Helicase Inhibitors with Antialphaviral Activity

Journal of Medicinal Chemistry(2025)10.1021/acs.jmedchem.5c00635

N/A

0DataRank · unranked

9 citations

John D. Sears, Kacey M. Talbot, Yuan-Wei Norman Su, Scott Houliston, Mohammad Anwar Hossain +27 more

A BRET biosensor for measuring uncompetitive engagement of PRMT5 complexes in cells

Nature Communications(2025)10.1038/s41467-025-65558-6

N/A

0DataRank · unranked

4 citations

Ani Michaud, Jakub Stefaniak, Usha Singh, Brynwood B. Mikulsky, James D. Vasta +14 more

Functionally active modulators targeting the LRRK2 WD40 repeat domain identified by FRASE-bot in CACHE Challenge #1

Chemical Science(2025)10.1039/d4sc07532c

N/A

0DataRank · unranked

5 citations

Marta Glavatskikh, Xiaowen Wang, Antonio Jesús Lara Ordóñez, Fengling Li, Irene Chau +17 more

Active Learning-Guided Hit Optimization for the Leucine-Rich Repeat Kinase 2 WDR Domain Based on In Silico Ligand-Binding Affinities

Journal of Chemical Information and Modeling(2025)10.1021/acs.jcim.5c00588

N/A

0DataRank · unranked

1 citations

Evgeny Gutkin, Francesco Gentile, Fuqiang Ban, S. Benjamin Koby, Fengling Li +19 more

Structure-based discovery of inhibitors of Mac1 domain of nonstructural protein-3 of SARS-CoV-2 by machine learning-augmented screening of chemical space

bioRxiv (Cold Spring Harbor Laboratory)(2025)10.1101/2025.09.05.674529

N/A

0DataRank · unranked

2 citations

Rahul Ravichandran, G.J. Correy, Oleksandra Herasymenko, Madhushika Silva, Suzanne Ackloo +11 more

A Live Cell BRET Probe to Quantify PRMT5-MTA Uncompetitive Target Engagement

ChemRxiv(2025)10.26434/chemrxiv-2025-318k4

N/A

0DataRank · unranked

0 citations

Ani Michaud, Jakub Stefaniak, Usha Singh, James D. Vasta, Michael Beck +11 more

Functionally active modulators targeting the LRRK2 WD40 repeat domain identified by FRASE-bot in CACHE Challenge #1

UNC Libraries(2025)10.17615/qcft-3792

N/A

0DataRank · unranked

0 citations

Suzanne Ackloo, C. Arrowsmith, Alma Seitova, Li F, Albina Bolotokova +17 more

CACHE Challenge #3: Targeting the Nsp3 Macrodomain of SARS-CoV-2

ChemRxiv(2025)10.26434/chemrxiv-2025-d1v7v

N/A

0DataRank · unranked

0 citations

Madhushika Silva, G.J. Correy, Abd Al‐Aziz A. Abu‐Saleh, Suzanne Ackloo, C. Arrowsmith +74 more

Discovery of a First-in-Class Small-Molecule Ligand for WDR91 Using DNA-Encoded Chemical Library Selection Followed by Machine Learning

UNC Libraries(2025)10.17615/d4ft-pp53

N/A

0DataRank · unranked

0 citations

John W. Cuozzo, Peter J. Brown, Jianwen A. Feng, Pegah Ghiabi, Ashley Hutchinson +20 more

P. Loppnau

Indexed papers

Top data-sharing exemplar

Papers