Christopher R. Bethel

Pilot corpus only

This score is computed over theSindex pilot corpus and does not cover the full scientific literature. Scores are relative to papers we have ingested — papers, authors, and institutions outside the pilot are not represented. Methodology.

Top 100%percentile

0Author DataRank

Indexed papers

0in pilot corpus

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Papers

Driven by 24 papers. Top paper: “Structural Insights into Ceftobiprole Inhibition of Pseudomonas aeruginosa Penicillin-Binding Protein 3”.

Structural Insights into Ceftobiprole Inhibition of Pseudomonas aeruginosa Penicillin-Binding Protein 3

Antimicrobial Agents and Chemotherapy(2020)10.1128/aac.00106-20

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14 citations

Christie Tang, Christopher R. Bethel, Krisztina M. Papp‐Wallace, Jacob Wyatt, Eric Desarbre +3 more

Carbapenem Use Is Driving the Evolution of Imipenemase 1 Variants

Antimicrobial Agents and Chemotherapy(2021)10.1128/aac.01714-20

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32 citations

Christopher R. Bethel, Pei W. Thomas, Ben A. Shurina, John-Paul Alao, Caitlyn A. Thomas +10 more

OXA-23 β-Lactamase Overexpression in Acinetobacter baumannii Drives Physiological Changes Resulting in New Genetic Vulnerabilities

mBio(2021)10.1128/mbio.03137-21

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32 citations

Marjan Farokhyfar, Anna R. Hutcheson, Alexander C. Anderson, Christopher R. Bethel, Robert A. Bonomo +3 more

Insights Into the Inhibition of MOX-1 β-Lactamase by S02030, a Boronic Acid Transition State Inhibitor

Frontiers in Microbiology(2021)10.3389/fmicb.2021.720036

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6 citations

Nayuta Furukawa, Emilia Caselli, Fabio Prati, Magdalena A. Taracila, Christopher R. Bethel +4 more

Penicillanic Acid Sulfones Inactivate the Extended-Spectrum β-Lactamase CTX-M-15 through Formation of a Serine-Lysine Cross-Link: an Alternative Mechanism of β-Lactamase Inhibition

mBio(2022)10.1128/mbio.01793-21

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17 citations

Catherine L. Tooke, Christopher R. Bethel, Benlian Wang, Christopher J. Arthur, Kate J. Heesom +6 more

Collateral Changes in Cell Physiology Associated with ADC-7 β-Lactamase Expression in Acinetobacter baumannii

Microbiology Spectrum(2023)10.1128/spectrum.04646-22

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17 citations

Marjan Farokhyfar, Alexander C. Anderson, Christopher R. Bethel, Robert A. Bonomo, Anthony J. Clarke +2 more

The directed evolution of NDM-1

Antimicrobial Agents and Chemotherapy(2023)10.1128/aac.00714-23

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4 citations

Zishuo Cheng, Christopher R. Bethel, Andrea M. Hujer, Aidan M. Sturgill, Kelechi Onuoha +4 more

The Structural Role of N170 in Substrate‐Assisted Deacylation in KPC‐2 β‐Lactamase

Angewandte Chemie International Edition(2024)10.1002/anie.202317315

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20 citations

Jing Gu, Shuang Chen, Christopher R. Bethel, Emma Marshall, Andrea M. Hujer +3 more

Synergistic effects of sulopenem in combination with cefuroxime or durlobactam against Mycobacterium abscessus

mBio(2024)10.1128/mbio.00609-24

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20 citations

Eunjeong Shin, Sebastian G. Kurz, Mark S. Plummer, Mary Nantongo, Christopher R. Bethel +8 more

ARGONAUT-III and -V: susceptibility of carbapenem-resistant Klebsiella pneumoniae and multidrug-resistant Pseudomonas aeruginosa to the bicyclic boronate β-lactamase inhibitor taniborbactam combined with cefepime

Antimicrobial Agents and Chemotherapy(2024)10.1128/aac.00751-24

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14 citations

Ayman M. Abdelhamed, Caryn E. Good, Andrew R Mack, Christopher R. Bethel, Steven H. Marshall +12 more

ARGONAUT-IV: susceptibility of carbapenemase-producing Klebsiella pneumoniae to the oral bicyclic boronate β-lactamase inhibitor ledaborbactam combined with ceftibuten

Antimicrobial Agents and Chemotherapy(2024)10.1128/aac.01127-24

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6 citations

Caryn E. Good, Ayman M. Abdelhamed, Andrew R Mack, Christopher R. Bethel, Steven H. Marshall +12 more

The interaction of the azetidine thiazole side chain with the active site loop (ASL) 3 drives the evolution of IMP metallo-β-lactamase against tebipenem

Antimicrobial Agents and Chemotherapy(2024)10.1128/aac.00687-24

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6 citations

Anna Cmolik, Christopher R. Bethel, Yoshikazu Ishii, Salvador I. Drusin, Diego M. Moreno +4 more

Machine Learning Models Identify Inhibitors of New Delhi Metallo-β-lactamase

Journal of Chemical Information and Modeling(2024)10.1021/acs.jcim.3c02015

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4 citations

Mahesh Aitha, Caitlyn A. Thomas, Aidan M. Sturgill, Mitch Fairweather, Amy Hu +19 more

Crystal structure of the class A extended-spectrum β-lactamase CTX-M-96 in complex with relebactam at 1.03 Angstrom resolution

Antimicrobial Agents and Chemotherapy(2024)10.1128/aac.01721-23

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3 citations

M.M. Rodríguez, Pedro Penzotti, Christopher R. Bethel, Gabriel Gutkind, Robert A. Bonomo +3 more

Ω-Loop mutations control dynamics of the active site by modulating the hydrogen-bonding network in PDC-3 β-lactamase

bioRxiv (Cold Spring Harbor Laboratory)(2024)10.1101/2024.02.04.578824

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5 citations

Andrew R Mack, Andrea M. Hujer, Christopher R. Bethel, Robert A. Bonomo, Shozeb Haider +1 more

The Structural Role of N170 in Substrate‐Assisted Deacylation in KPC‐2 β‐Lactamase

Angewandte Chemie(2024)10.1002/ange.202317315

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0 citations

Jing Gu, Shuang Chen, Christopher R. Bethel, Emma Marshall, Andrea M. Hujer +3 more

Cefiderocol “under siege”? Understanding the rise of NDM-mediated resistance to novel agents

Chemical Science(2025)10.1039/d5sc02122g

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26 citations

Pablo E. Tomatis, María F. Mojica, Christopher R. Bethel, Magdalena Rodríguez Saravia, Salvador I. Drusin +9 more

Emerging resistance to novel β-lactam β-lactamase inhibitor combinations in Klebsiella pneumoniae bearing KPC variants

Journal of Global Antimicrobial Resistance(2025)10.1016/j.jgar.2025.07.011

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12 citations

Germán M. Traglia, Lucía Maccari, Sonia Gómez, María Belén Sanz, Usman Akhtar +12 more

Exploring β-lactam interactions with DacB1: unraveling optimal therapies for combating drug-resistant Mycobacterium tuberculosis

mBio(2025)10.1128/mbio.01372-25

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2 citations

David C. Nguyen, Eunjeong Shin, Christopher R. Bethel, Magdalena A. Taracila, Khalid M Dousa +9 more

Structure and mechanism of taniborbactam inhibition of the cefepime-hydrolyzing, partial R2-loop deletion Pseudomonas -derived cephalosporinase variant PDC-88

Antimicrobial Agents and Chemotherapy(2025)10.1128/aac.00078-25

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2 citations

Vijay Kumar, Christopher R. Bethel, Magdalena A. Taracila, Brittany Miller, Tsuyoshi Uehara +5 more

Ω-Loop mutations control dynamics of the active site by modulating the hydrogen-bonding network in PDC-3 β-lactamase

eLife(2025)10.7554/elife.107688.2

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1 citations

Andrew R Mack, Andrea M. Hujer, Christopher R. Bethel, Robert A. Bonomo, Shozeb Haider +1 more

Inhibitor Affinity Differs among Clinical Variants of IMP Metallo-β-Lactamases: Analysis and Implications for Inhibitor Design

ACS Infectious Diseases(2025)10.1021/acsinfecdis.5c00138

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0 citations

John Paul Alao, Thomas Smisek, Zishuo Cheng, Christopher R. Bethel, Kundi Yang +8 more

Ω-Loop mutations control dynamics of the active site by modulating the hydrogen-bonding network in PDC-3 β-lactamase

eLife(2025)10.7554/elife.107688

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0 citations

Andrew R Mack, Andrea M. Hujer, Christopher R. Bethel, Robert A. Bonomo, Shozeb Haider +1 more

ARGONAUT-IV: susceptibility of carbapenemase-producing Klebsiella pneumoniae to the oral bicyclic boronate β-lactamase inhibitor ledaborbactam combined with ceftibuten.

UNC Libraries(2025)10.17615/tde0-ye85

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0 citations

Vance G. Fowler, Daniel D. Rhoads, Andrea M. Hujer, Robert A Bonomo, Christopher R. Bethel +12 more