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Kaitlyn M. Cahuzac

Kaitlyn M. Cahuzac

Pilot corpus only

This score is computed over theSindex pilot corpus and does not cover the full scientific literature. Scores are relative to papers we have ingested — papers, authors, and institutions outside the pilot are not represented. Methodology.

Top 100%percentile

0Author DataRank

Indexed papers

0in pilot corpus

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Papers

Driven by 5 papers. Top paper: “AKT Degradation Selectively Inhibits the Growth of PI3K/PTEN Pathway–Mutant Cancers with Wild-Type KRAS and BRAF by Destabilizing Aurora Kinase B”.

AKT Degradation Selectively Inhibits the Growth of PI3K/PTEN Pathway–Mutant Cancers with Wild-Type KRAS and BRAF by Destabilizing Aurora Kinase B

Cancer Discovery(2021)10.1158/2159-8290.cd-20-0815

N/A

0DataRank · unranked

66 citations

Xufen Yu, Tiphaine Martin, Ankita Bansal, Kakit Cheung, Abigail Lubin +15 more

Design, Synthesis, and Evaluation of Potent, Selective, and Bioavailable AKT Kinase Degraders

Journal of Medicinal Chemistry(2021)10.1021/acs.jmedchem.1c01476

N/A

0DataRank · unranked

54 citations

Jia Xu, Ling Xie, Li Wang, Yudao Shen, Kaitlyn M. Cahuzac +5 more

Novel Allosteric Inhibitor-Derived AKT Proteolysis Targeting Chimeras (PROTACs) Enable Potent and Selective AKT Degradation in KRAS/BRAF Mutant Cells

Journal of Medicinal Chemistry(2022)10.1021/acs.jmedchem.2c01454

N/A

0DataRank · unranked

35 citations

Jia Xu, Kaitlyn M. Cahuzac, Ling Xie, Yudao Shen, Xian Chen +4 more

Discovery of Potent, Selective, and In Vivo Efficacious AKT Kinase Protein Degraders via Structure–Activity Relationship Studies

Journal of Medicinal Chemistry(2022)10.1021/acs.jmedchem.1c02165

N/A

0DataRank · unranked

39 citations

Jia Xu, Yudao Shen, Kaitlyn M. Cahuzac, Kwang‐Su Park, Brandon Dale +4 more

AKT activation because of PTEN loss upregulates xCT via GSK3β/NRF2, leading to inhibition of ferroptosis in PTEN-mutant tumor cells

Cell Reports(2023)10.1016/j.celrep.2023.112536

N/A

0DataRank · unranked

51 citations

Abigail Lubin, Kaitlyn Bosch, Nicole Stokes, Sarah Mense Shoenfeld, Royce Zhou +4 more