Puranik Purushottamachar

Pilot corpus only

This score is computed over theSindex pilot corpus and does not cover the full scientific literature. Scores are relative to papers we have ingested — papers, authors, and institutions outside the pilot are not represented. Methodology.

Top 100%percentile

0Author DataRank

Indexed papers

0in pilot corpus

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Papers

Driven by 8 papers. Top paper: “Sulforaphane covalently interacts with the transglutaminase 2 cancer maintenance protein to alter its structure and suppress its activity”.

Sulforaphane covalently interacts with the transglutaminase 2 cancer maintenance protein to alter its structure and suppress its activity

Molecular Carcinogenesis(2021)10.1002/mc.23356

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0DataRank · unranked

16 citations

Gautam Adhikary, Henryk Szmacinski, Joseph R. Lakowicz, David J. Weber, Raquel Godoy‐Ruiz +5 more

Transcriptome profiling reveals that VNPP433‐3β, the lead next‐generation galeterone analog inhibits prostate cancer stem cells by downregulating epithelial–mesenchymal transition and stem cell markers

Molecular Carcinogenesis(2022)10.1002/mc.23406

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0DataRank · unranked

31 citations

Retheesh S. Thankan, Puranik Purushottamachar, Weiliang Huang, Maureen A. Kane, Yuji Zhang +4 more

Novel AR/AR-V7 and Mnk1/2 Degrader, VNPP433-3β: Molecular Mechanisms of Action and Efficacy in AR-Overexpressing Castration Resistant Prostate Cancer In Vitro and In Vivo Models

Cells(2022)10.3390/cells11172699

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0DataRank · unranked

15 citations

Retheesh S. Thankan, Puranik Purushottamachar, Weiliang Huang, Maureen A. Kane, Yuji Zhang +4 more

Large-scale synthesis of galeterone and lead next generation galeterone analog VNPP433-3β

Steroids(2022)10.1016/j.steroids.2022.109062

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0DataRank · unranked

10 citations

Elizabeth Thomas, Retheesh S. Thankan, V. F. Rudchenko, Guangfei Huang, Vincent C.O. Njar +1 more

Targeted Degradation of Androgen Receptor by VNPP433-3β in Castration-Resistant Prostate Cancer Cells Implicates Interaction with E3 Ligase MDM2 Resulting in Ubiquitin-Proteasomal Degradation

Cancers(2023)10.3390/cancers15041198

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0DataRank · unranked

17 citations

Retheesh S. Thankan, Puranik Purushottamachar, David J. Weber, Vincent C.O. Njar, Elizabeth Thomas

VNLG-152R and its deuterated analogs potently inhibit/repress triple/quadruple negative breast cancer of diverse racial origins in vitro and in vivo by upregulating E3 Ligase Synoviolin 1 (SYVN1) and inducing proteasomal degradation of MNK1/2

Frontiers in Oncology(2023)10.3389/fonc.2023.1240996

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0DataRank · unranked

4 citations

Elizabeth Thomas, Puranik Purushottamachar, David J. Weber, Vidya P. Ramamurthy, Weiliang Huang +3 more

Salinization Dramatically Enhance the Anti-Prostate Cancer Efficacies of AR/AR-V7 and Mnk1/2 Molecular Glue Degraders, Galeterone and VNPP433-3β Which Outperform Docetaxel and Enzalutamide in CRPC CWR22Rv1 Xenograft Mouse Model

Bioorganic Chemistry(2023)10.1016/j.bioorg.2023.106700

N/A

0DataRank · unranked

11 citations

Elizabeth Thomas, Puranik Purushottamachar, David J. Weber, Vincent C.O. Njar, Retheesh S. Thankan

Murine toxicology and pharmacokinetics of lead next generation galeterone analog, VNPP433-3β

Steroids(2023)10.1016/j.steroids.2023.109184

N/A

0DataRank · unranked

9 citations

Retheesh S. Thankan, Puranik Purushottamachar, Jianxia Guo, Robert A. Parise, Jan H. Beumer +2 more