Carrie O’Connor

Pilot corpus only

This score is computed over theSindex pilot corpus and does not cover the full scientific literature. Scores are relative to papers we have ingested — papers, authors, and institutions outside the pilot are not represented. Methodology.

Top 100%percentile

0Author DataRank

Indexed papers

0in pilot corpus

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Papers

Driven by 7 papers. Top paper: “Discovery of 6-substituted thieno[2,3-d]pyrimidine analogs as dual inhibitors of glycinamide ribonucleotide formyltransferase and 5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase in de novo purine nucleotide biosynthesis in folate receptor expressing human tumors”.

Discovery of 6-substituted thieno[2,3-d]pyrimidine analogs as dual inhibitors of glycinamide ribonucleotide formyltransferase and 5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase in de novo purine nucleotide biosynthesis in folate receptor expressing human tumors

Bioorganic & Medicinal Chemistry(2021)10.1016/j.bmc.2021.116093

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0DataRank · unranked

12 citations

Nian Tong, Jennifer Wong-Roushar, Carrie O’Connor, Xilin Zhou, Zhanjun Hou +8 more

Targeted therapy of pyrrolo[2,3-d]pyrimidine antifolates in a syngeneic mouse model of high grade serous ovarian cancer and the impact on the tumor microenvironment

Scientific Reports(2022)10.1038/s41598-022-14788-5

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0DataRank · unranked

15 citations

Lisa Rubinsak, Agnes Malysa, Sijana H. Dzinic, Manasa Ravindra, Mathew Schneider +11 more

Structure-Based Design of Transport-Specific Multitargeted One-Carbon Metabolism Inhibitors in Cytosol and Mitochondria

Journal of Medicinal Chemistry(2023)10.1021/acs.jmedchem.3c00763

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0DataRank · unranked

17 citations

Jade M. Katinas, Tejashree Magdum, Khushbu Shah, Jennifer E. Wong, Carrie O’Connor +7 more

Multitargeted 6-Substituted Thieno[2,3-d]pyrimidines as Folate Receptor-Selective Anticancer Agents that Inhibit Cytosolic and Mitochondrial One-Carbon Metabolism

ACS Pharmacology & Translational Science(2023)10.1021/acsptsci.3c00020

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0DataRank · unranked

6 citations

Jennifer Wong-Roushar, Adrianne Wallace-Povirk, Yesha V. Shah, Morgan C. Nyman, Jade M. Katinas +10 more

Mitochondrial and Cytosolic One-Carbon Metabolism Is a Targetable Metabolic Vulnerability in Cisplatin-Resistant Ovarian Cancer

Molecular Cancer Therapeutics(2024)10.1158/1535-7163.mct-23-0550

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0DataRank · unranked

15 citations

Carrie O’Connor, Aamod S. Dekhne, Xun Bao, Md. Junayed Nayeen, Mathew Schneider +11 more

Role of Mitochondrial and Cytosolic Folylpolyglutamate Synthetase in One-Carbon Metabolism and Antitumor Efficacy of Mitochondrial-Targeted Antifolates

Molecular Pharmacology(2024)10.1124/molpharm.124.000912

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0DataRank · unranked

12 citations

Mathew Schneider, Jade M. Katinas, Md. Junayed Nayeen, Khushbu Shah, Tejashree Magdum +9 more

Pharmacodynamic determinants of mitochondrial one-carbon flux and serine hydroxymethyltransferase inhibition in human tumors

Drug Metabolism and Disposition(2025)10.1016/j.dmd.2025.100120

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0DataRank · unranked

2 citations

Carrie O’Connor, Xun Bao, Md. Junayed Nayeen, Tejashree Magdum, Abhishekh Sharma +7 more