David S. Umbaugh

Pharmacology, Toxicology and PharmaceuticsMedicine

Pilot corpus only

This score is computed over theSindex pilot corpus and does not cover the full scientific literature. Scores are relative to papers we have ingested — papers, authors, and institutions outside the pilot are not represented. Methodology.

Top 100%percentile

0Author DataRank

Indexed papers

0in pilot corpus

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Papers

Driven by 18 papers. Top paper: “Regulation of Liver Regeneration by Hepatocyte O-GlcNAcylation in Mice”.

Regulation of Liver Regeneration by Hepatocyte O-GlcNAcylation in Mice

Cellular and Molecular Gastroenterology and Hepatology(2022)10.1016/j.jcmgh.2022.01.014

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0.500DataRank · unranked

27 citations

Steven R. McGreal, David S. Umbaugh, Wendena S. Parkes, Manasi Kotulkar, Sarah Abernathy +9 more

Regulation of Liver Regeneration by hepatocyte O-GlcNAcylation in mice

bioRxiv (Cold Spring Harbor Laboratory)(2021)10.1101/2021.10.14.464401

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0.269DataRank · unranked

5 citations

Steven R. McGreal, David S. Umbaugh, Wendena S. Parkes, Manasi Kotulkar, Sarah Abernathy +9 more

Mixed lineage kinase domain-like protein deficiency exacerbates early injury in a mouse model of acetaminophen hepatotoxicity

Toxicological Sciences(2025)10.1093/toxsci/kfaf022

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0.104DataRank · unranked

1 citations

David S. Umbaugh, Sawyer Smith, Jephte Y. Akakpo, Hartmut Jaeschke, Anup Ramachandran +1 more

Spatial Reconstruction of the Early Hepatic Transcriptomic Landscape After an Acetaminophen Overdose Using Single-Cell RNA-Sequencing

Toxicological Sciences(2021)10.1093/toxsci/kfab052

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0DataRank · unranked

40 citations

Anup Ramachandran, Hartmut Jaeschke, David S. Umbaugh

Mitochondrial Dynamics in Drug-Induced Liver Injury

Livers(2021)10.3390/livers1030010

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0DataRank · unranked

29 citations

David S. Umbaugh, Hartmut Jaeschke, Anup Ramachandran

Recovered Hepatocytes Promote Macrophage Apoptosis Through CXCR4 After Acetaminophen-Induced Liver Injury in Mice

Toxicological Sciences(2022)10.1093/toxsci/kfac057

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0DataRank · unranked

15 citations

David S. Umbaugh, Eileen L Huang, Olamide B. Adelusi, Giselle Sánchez-Guerrero, Anup Ramachandran +2 more

The chemokine CXCL14 is a novel early prognostic biomarker for poor outcome in acetaminophen-induced acute liver failure

Hepatology(2023)10.1097/hep.0000000000000665

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0DataRank · unranked

24 citations

Nga Nguyen, Steven C. Curry, Jody A. Rule, William M. Lee, Anup Ramachandran +3 more

Translocation of Adenosine A2B Receptor to Mitochondria Influences Cytochrome P450 2E1 Activity after Acetaminophen Overdose

Livers(2023)10.3390/livers4010002

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0DataRank · unranked

0 citations

David S. Umbaugh, Abhay A. Ramachandran, Antonio Artigues, Hartmut Jaeschke, Anup Ramachandran +1 more

The p21+ perinecrotic hepatocytes produce the chemokine CXCL14 after a severe acetaminophen overdose promoting hepatocyte injury and delaying regeneration

Toxicology(2024)10.1016/j.tox.2024.153804

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0DataRank · unranked

26 citations

Nga Nguyen, Sawyer Smith, Anup Ramachandran, Hartmut Jaeschke, David S. Umbaugh

Biomarker discovery in acetaminophen hepatotoxicity: leveraging single-cell transcriptomics and mechanistic insight

Expert Review of Clinical Pharmacology(2024)10.1080/17512433.2024.2306219

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0DataRank · unranked

8 citations

Hartmut Jaeschke, David S. Umbaugh

Cellular senescence in liver diseases: From molecular drivers to therapeutic targeting

Journal of Hepatology(2025)10.1016/j.jhep.2025.08.021

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0DataRank · unranked

22 citations

David S. Umbaugh, Niansheng Ren, Anna Mae Diehl, Kuo Du

Redefining senescence through hepatocyte fate changes in liver diseases

Trends in Endocrinology and Metabolism(2025)10.1016/j.tem.2025.08.003

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0DataRank · unranked

6 citations

Anna Mae Diehl, Kuo Du, David S. Umbaugh

cGAS Inhibits ALDH2 to Suppress Lipid Droplet Function and Regulate MASLD Progression

Advanced Science(2025)10.1002/advs.202508576

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0DataRank · unranked

4 citations

Yu Deng, Jianfeng Chen, Quentin Hahn, David S. Umbaugh, Zhigang Zhang +10 more

The endothelial growth factor Angiopoietin-2 is an accurate prognostic biomarker in patients with acetaminophen-induced acute liver failure

medRxiv(2025)10.1101/2025.02.19.25322567

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0DataRank · unranked

1 citations

Nga Nguyen, Steven C. Curry, Jody A. Rule, William M. Lee, Anup Ramachandran +3 more

Mitochondrial protein adduct and superoxide generation are prerequisites for early activation of c-jun N-terminal kinase within the cytosol after an acetaminophen overdose in mice

Toxicology Letters(2020)10.1016/j.toxlet.2020.12.005

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0DataRank · unranked

68 citations

Kuo Du, Jephte Y. Akakpo, David S. Umbaugh, Hartmut Jaeschke, Anup Ramachandran +1 more

The endothelial growth factor angiopoietin-2 is an accurate prognostic biomarker in patients with acetaminophen-induced acute liver failure

Toxicological Sciences(2025)10.1093/toxsci/kfaf130

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0DataRank · unranked

0 citations

Nga Nguyen, Steven C. Curry, Jody A. Rule, William M. Lee, Anup Ramachandran +15 more

Recommendations for the use of the acetaminophen hepatotoxicity model for mechanistic studies and how to avoid common pitfalls

Acta Pharmaceutica Sinica B(2021)10.1016/j.apsb.2021.09.023

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0DataRank · unranked

143 citations

Olamide B. Adelusi, Jephte Y. Akakpo, Nga Nguyen, Giselle Sánchez-Guerrero, David S. Umbaugh +3 more

Mitochondrial Membrane Potential Drives Early Change in Mitochondrial Morphology After Acetaminophen Exposure

Toxicological Sciences(2021)10.1093/toxsci/kfaa188

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0DataRank · unranked

51 citations

Nga Nguyen, Hartmut Jaeschke, Anup Ramachandran, David S. Umbaugh