Pilot corpus: NIH-funded biomedical datasets. Any DOI can be scored on demand — network effects sharpen as coverage grows.

U1‐70K and U1A and tau pathogenesis in demented and non‐demented individuals with Down syndrome

Alzheimer s & Dementia(2025)10.1002/alz.70474Source: DataRank Database

U1‐70K and U1A and tau pathogenesis in demented and non‐demented individuals with Down syndrome is a research paper published in Alzheimer s & Dementia (2025). On theSindex it has a DataRank of 0. It has been cited 3 times.

N/A

0DataRank · unranked

Scored on demand from live citation data

Open Access3 citations

Free full text

Cite:

DataRank reads this dataset's downstream impact straight off the citation graph — no black box, no proprietary weighting. How is this computed?

›Methodology & internals

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Pipeline:MetadataData-paper checkEnrichmentCitation networkScoring

Enrichment:Funding (21 grants)Impact (FWCI 3.33)OA: hybridTopics (73)IDs (PubMed, OpenAlex)

FAIR Checklist

Context only (not used in score)

Findable (1/2)

Has DOI

Accessible (1/2)

Open Access

Interoperable (0/2)

Reusable (0/3)

FAIR checklist signals are shown for context only and do not affect DataRank scoring.

Run a calibrated FAIR evaluation for this paper →

We only score data papers we can read in full — never from an abstract alone.

Authors (7)

Jennifer C. Miguel ORCID,Muhammad Nadeem ORCID,Michael Malek‐Ahmadi ORCID,Chadwick M. Hales ORCID,Elizabeth Head ORCID

Live enrichment

PubMed:40762109 OpenAlex:https://openalex.org/W4412954019

National Institutes of Health

Grant: P01AG014449

National Institutes of Health

Grant: RF1AG061566

National Institutes of Health

Grant: RF1AG081286

National Institutes of Health

Grant: P30AG066511

National Institutes of Health

Grant: NS087121

National Institutes of Health

Grant: P30AG066519

National Institutes of Health

Grant: U19AG068054

National Institutes of Health

Grant: P30AG072980

National Institutes of Health

Grant: P30AG019610

BrightFocus Foundation

Grant: CA2018010

National Institutes of Health

Grant: 3P30AG066519-01S1

The Alzheimer's Disease Research Center at the University of California, Irvine

National Institutes of Health

Grant: 1P01AG014449-02

CORE--STATISTICS AND DATA MANAGEMENT

National Institutes of Health

Grant: 3P30AG066511-03S2

Piloting a web-based neuropathology image resource for the ADRC community

National Institutes of Health

Grant: 5P30AG072980-02

Arizona Alzheimer's Disease Research Center

National Institutes of Health

Grant: 1U19AG068054-01

Alzheimer Biomarker Consortium - Down Syndrome (ABC-DS)

National Institutes of Health

Grant: 2P30AG019610-11

Education and Information Transfer Core

National Institutes of Health

Grant: 1RF1AG081286-01

Default mode network dysfunction in Down Syndrome

National Institutes of Health

Grant: 7RF1AG061566-02

Tau pathology in Down syndrome and Alzheimer's

National Institutes of Health

Grant: 1K08NS087121-01

Investigating RNA splicing factor aggregations in Alzheimer's disease and CTE

NINDS NIH HHS

Grant: K08 NS087121

Barrow Neurological Foundation

FWCI

3.33

Citation Percentile

0.9%

Citation Trend

2025

2026

hybridLicense: cc-by-nc-nd

journalhttps://onlinelibrary.wiley.com/doi/pdfdirect/10.1002/alz.70474

publisherhttps://onlinelibrary.wiley.com/doi/pdfdirect/10.1002/alz.70474

publisherhttps://alz-journals.onlinelibrary.wiley.com/doi/pdf/10.1002/alz.70474

journalhttps://doi.org/10.1002/alz.70474

repositoryhttps://pubmed.ncbi.nlm.nih.gov/40762109

Fields of Study

Down syndrome and intellectual disability researchRNA Research and SplicingGenetic Neurodegenerative Diseases03 medical and health sciences0302 clinical medicineHumansDown Syndrometau ProteinsFemaleMaleMiddle AgedDementiaAgedFrontal LobeSerine-Arginine Splicing FactorsAdultHeterogeneous-Nuclear Ribonucleoprotein Group A-BRibonucleoprotein, U1 Small NuclearProtein-Tyrosine KinasesProtein Serine-Threonine Kinases

MeSH Terms

Serine-Arginine Splicing FactorsAdultAgedDementiaDown SyndromeFemaleFrontal LobeHumansMaleMiddle AgedProtein-Tyrosine Kinasestau ProteinsProtein Serine-Threonine KinasesRibonucleoprotein, U1 Small NuclearHeterogeneous-Nuclear Ribonucleoprotein Group A-B

Keywords

PathogenesisDementiaCortex (anatomy)Frontal cortexNeuroscienceRNA splicingCerebral cortexTangleWestern blotBiologyTemporal cortexPsychologyPathologyMedicineInternal medicineGeneticsDiseaseGeneMaleAdultSerine-Arginine Splicing Factorstau ProteinsMiddle AgedProtein-Tyrosine KinasesProtein Serine-Threonine KinasesFrontal LobeRibonucleoprotein, U1 Small NuclearHeterogeneous-Nuclear Ribonucleoprotein Group A-BHumansFemaleDown SyndromeResearch ArticleAgedU1‐70Kamyloidspliceosomesplicing proteinstau