Elizabeth Head

MedicineNeuroscienceBiochemistry, Genetics and Molecular Biology

Pilot corpus only

This score is computed over theSindex pilot corpus and does not cover the full scientific literature. Scores are relative to papers we have ingested — papers, authors, and institutions outside the pilot are not represented. Methodology.

Top 2%percentile

2.8Author DataRank

Indexed papers

6in pilot corpus

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Why this DataRank?

An author's DataRank is the sum of the DataRanks of all 6 indexed papers attributed to them. A prolific author with many moderate-impact papers can outrank one with a single high-impact paper.

Author scores recompute whenever paper DataRanks are refreshed, so this number lags the underlying paper scores by at most one batch run.

Read the full methodology →

The highest-impact dataset this researcher has shared, ranked by DataRank — the single contribution doing the most to lift their data-sharing standing.

Comprehensive assessment of TDP-43 neuropathology data in the National Alzheimer’s Coordinating Center database

Acta Neuropathologica(2024)10.1007/s00401-024-02728-8

Top 29%

0.695DataRank

Top 29%20 citations

Katelynn M. Nguyen, Lorena Sordo, Kiana A. Scambray, Elizabeth Head, Claudia H. Kawas +4 more

Papers

Driven by 111 papers — median percentile 61. Top paper: “A retrotransposon storm marks clinical phenoconversion to late-onset Alzheimer’s disease”.

A retrotransposon storm marks clinical phenoconversion to late-onset Alzheimer’s disease

GeroScience(2022)10.1007/s11357-022-00580-w

N/A

1.2DataRank · unranked

41 citations

Maria Giulia Bacalini, Ricardo Miramontes, Alessio Boattini, Cristian Taccioli, Giorgia Modenini +11 more

Comparison of amyloid burden in individuals with Down syndrome versus autosomal dominant Alzheimer's disease: a cross-sectional study

The Lancet Neurology(2022)10.1016/s1474-4422(22)00408-2

N/A

1.1DataRank · unranked

56 citations

Brian A. Gordon, Julie K. Wisch, Shaney Flores, Rachel L. Henson, Omar H. Butt +95 more

Modulating heart rate oscillation affects plasma amyloid beta and tau levels in younger and older adults

Scientific Reports(2023)10.1038/s41598-023-30167-0

N/A

1.1DataRank · unranked

39 citations

Jeremy Rouanet, Alessandra Cadete Martini, Kaoru Nashiro, Hyun Joo Yoo, Shai Porat +8 more

Cholesterol and matrisome pathways dysregulated in astrocytes and microglia

Cell(2022)10.1016/j.cell.2022.05.017

N/A

0.902DataRank · unranked

407 citations

Qian Lü, Nina H. Pipalia, Michael J. Chao, Shuang Liang, Yang Shi +16 more

Alzheimer's disease associated with Down syndrome: a genetic form of dementia

The Lancet Neurology(2021)10.1016/s1474-4422(21)00245-3

N/A

0.885DataRank · unranked

363 citations

Shahid Zaman, Sigan L. Hartley, Michael S. Rafii, Elizabeth Head, María Carmona‐Iragui +1 more

Absence of microglia promotes diverse pathologies and early lethality in Alzheimer’s disease mice

Cell Reports(2022)10.1016/j.celrep.2022.110961

N/A

0.785DataRank · unranked

187 citations

Samuel Morabito, Emma Danhash, Amanda McQuade, Jessica Sanchez, Emily Miyoshi +16 more

Comprehensive assessment of TDP-43 neuropathology data in the National Alzheimer’s Coordinating Center database

Acta Neuropathologica(2024)10.1007/s00401-024-02728-8

Top 29%

0.695DataRank

Top 29%20 citations

Katelynn M. Nguyen, Lorena Sordo, Kiana A. Scambray, Elizabeth Head, Claudia H. Kawas +4 more

Opportunities, barriers, and recommendations in Down syndrome research

Translational Science of Rare Diseases(2021)10.3233/trd-200090

N/A

0.692DataRank · unranked

100 citations

Angelika Amon, Leonard Abbeduto, Stamatis Agiovlasitis, Tarek Alsaied, Heather A. Anderson +47 more

Proteomic profiles for Alzheimer's disease and mild cognitive impairment among adults with Down syndrome spanning serum and plasma: An Alzheimer's Biomarker Consortium–Down Syndrome (ABC–DS) study

Alzheimer s & Dementia Diagnosis Assessment & Disease Monitoring(2020)10.1002/dad2.12039

Top 30%

0.674DataRank

Top 30%23 citations

Fan Zhang, Nicole Schupf, Sharon J. Krinsky‐McHale, James Hall, Mark Mapstone +18 more

Brain insulin resistance triggers early onset Alzheimer disease in Down syndrome

Neurobiology of Disease(2020)10.1016/j.nbd.2020.104772

N/A

0.641DataRank · unranked

71 citations

Chiara Lanzillotta, Fabio Di Domenico, Elizabeth Head, D. Allan Butterfield, Marzia Perluigi +2 more

The Alzheimer's Biomarker Consortium–Down Syndrome (ABC‐DS): A 10‐year report

Alzheimer s & Dementia(2025)10.1002/alz.70294

N/A

0.601DataRank · unranked

22 citations

Mark Mapstone, Sigan L. Hartley, Howard Andrews, Brad T. Christian, Joseph H. Lee +20 more

Plasma Total-Tau and Neurofilament Light Chain as Diagnostic Biomarkers of Alzheimer’s Disease Dementia and Mild Cognitive Impairment in Adults with Down Syndrome

Journal of Alzheimer s Disease(2020)10.3233/jad-201167

N/A

0.598DataRank · unranked

53 citations

Michael S. Rafii, Fan Zhang, James Hall, David Julovich, Beau M. Ances +20 more

Comparison of tau spread in people with Down syndrome versus autosomal-dominant Alzheimer's disease: a cross-sectional study

The Lancet Neurology(2024)10.1016/s1474-4422(24)00084-x

N/A

0.542DataRank · unranked

36 citations

Nicole S. McKay, Anna H. Boerwinkle, James L. Kennedy, Shaney Flores, Benjamin L. Handen +86 more

Aβ and tau prions feature in the neuropathogenesis of Down syndrome

Proceedings of the National Academy of Sciences(2022)10.1073/pnas.2212954119

N/A

0.520DataRank · unranked

31 citations

Alison M. Maxwell, Erika Castillo, Atsushi Aoyagi, Caroline Graff, Martin Ingelsson +8 more

Multimodal neuroimaging data from a 5-week heart rate variability biofeedback randomized clinical trial

Scientific Data(2023)10.1038/s41597-023-02396-5

Top 37%

0.518DataRank

Top 37%15 citations

Kaoru Nashiro, Jungwon Min, Christine Cho, Noah Mercer, Shelby L. Bachman +19 more

Markers of early changes in cognition across cohorts of adults with Down syndrome at risk of Alzheimer's disease

Alzheimer s & Dementia Diagnosis Assessment & Disease Monitoring(2021)10.1002/dad2.12184

N/A

0.515DataRank · unranked

30 citations

R. Asaad Baksh, Bessy Benejam, Jessica Beresford‐Webb, Antonia Coppus, Juan Fortea +14 more

Cerebrovascular disease is associated with Alzheimer’s plasma biomarker concentrations in adults with Down syndrome

Brain Communications(2024)10.1093/braincomms/fcae331

N/A

0.510DataRank · unranked

29 citations

Patrick J. Lao, Mohamad J. Alshikho, Olivia M. Ericsson, Batool Rizvi, Melissa Petersen +70 more

Timeline to symptomatic Alzheimer's disease in people with Down syndrome as assessed by amyloid-PET and tau-PET: a longitudinal cohort study

The Lancet Neurology(2024)10.1016/s1474-4422(24)00426-5

N/A

0.505DataRank · unranked

28 citations

Matthew Zammit, Jiebiao Wang, Benjamin L. Handen, Tobey J. Betthauser, Charles M. Laymon +71 more

Transcript errors generate amyloid-like proteins in human cells

Nature Communications(2024)10.1038/s41467-024-52886-2

N/A

0.482DataRank · unranked

12 citations

Yi Kou, Sarah J. Shemtov, Bert M. Verheijen, Ilse Flores, Kayla Love +26 more

Evaluating the updated LATE‐NC staging criteria using data from NACC

Alzheimer s & Dementia(2024)10.1002/alz.14262

Top 40%

0.480DataRank

Top 40%11 citations

Katelynn M. Nguyen, Lorena Sordo, Kiana A. Scambray, Elizabeth Head, Claudia H. Kawas +4 more

Obstructive sleep apnea, cerebrovascular disease, and amyloid in older adults with Down syndrome across the Alzheimer’s continuum

SLEEP Advances(2022)10.1093/sleepadvances/zpac013

N/A

0.457DataRank · unranked

20 citations

Molly E. Zimmerman, Sigan L. Hartley, José Gutierrez, David B. Keator, Kay C. Igwe +16 more

LATE-NC risk alleles (in TMEM106B, GRN, and ABCC9 genes) among persons with African ancestry

Journal of Neuropathology & Experimental Neurology(2023)10.1093/jnen/nlad059

N/A

0.449DataRank · unranked

19 citations

David W. Fardo, Lincoln M. P. Shade, James D. Bowen, Paul K. Crane, Gail P. Jarvik +94 more

Exploring the role of sex differences in Alzheimer's disease pathogenesis in Down syndrome

Frontiers in Neuroscience(2022)10.3389/fnins.2022.954999

N/A

0.449DataRank · unranked

19 citations

Alessandra Cadete Martini, Elizabeth Head, Elizabeth J. Andrews

Amyloid-β predominant Alzheimer’s disease neuropathologic change

Brain(2024)10.1093/brain/awae325

N/A

0.425DataRank · unranked

16 citations

Yuriko Katsumata, Xian Wu, Khine Zin Aung, David W. Fardo, Shelley L. Forrest +95 more

The history of Down syndrome–associated Alzheimer's disease; past, present, and future

Alzheimer s & Dementia(2025)10.1002/alz.70158

N/A

0.385DataRank · unranked

12 citations

María Carmona‐Iragui, Ira T. Lott, Elizabeth Head, Thomas Wisniewski, Michael S. Rafii +8 more

The striatum is an early, accurate indicator of amyloid burden using [ 11 C]PiB in Down syndrome: Comparison of two radiotracers

Alzheimer s & Dementia(2025)10.1002/alz.70141

N/A

0.385DataRank · unranked

12 citations

Brecca Bettcher, Andrew K McVea, Alexandra H DiFilippo, Matthew Zammit, Lisette LeMerise +21 more

Differential involvement of hippocampal subfields in the relationship between Alzheimer's pathology and memory interference in older adults

Alzheimer s & Dementia Diagnosis Assessment & Disease Monitoring(2023)10.1002/dad2.12419

N/A

0.373DataRank · unranked

11 citations

Freddie Márquez, Myra S. Larson, John Janecek, Blake A. Miranda, Jessica A. Noche +8 more

Iron associated lipid peroxidation in Alzheimer’s disease is increased in lipid rafts with decreased ferroptosis suppressors, tested by chelation in mice

bioRxiv (Cold Spring Harbor Laboratory)(2023)10.1101/2023.03.28.534324

N/A

0.345DataRank · unranked

9 citations

José A. Godoy-Lugo, Gilberto Garcia, Justine Silva, Minhoo Kim, Amy Christensen +10 more

Correlating hippocampal and amygdala volumes with neuropathological burden in Down syndrome and Alzheimer’s disease and related neurodegenerative pathologies using 7T postmortem MRI

Journal of Neuropathology & Experimental Neurology(2025)10.1093/jnen/nlaf010

N/A

0.312DataRank · unranked

7 citations

Jinghang Li, Jacob Berardinelli, Hecheng Jin, Tales Santini, Jaehoon Noh +69 more

The effects of mosaicism on biological and clinical markers of Alzheimer's disease in adults with Down syndrome

EBioMedicine(2024)10.1016/j.ebiom.2024.105433

N/A

0.299DataRank · unranked

6 citations

Lam‐Ha T. Dang, Alice Lee, Sharon J. Krinsky‐McHale, Deborah Pang, Lisa Melilli +72 more

Spontaneous cerebrovascular reactivity at rest in older adults with and without mild cognitive impairment and memory deficits

Alzheimer s & Dementia(2024)10.1002/alz.14396

N/A

0.292DataRank · unranked

6 citations

John Paul M Alitin, Arunima Kapoor, Shubir Dutt, Trevor Lohman, Isabel J. Sible +13 more

Postmortem Neocortical 3H-PiB Binding and Levels of Unmodified and Pyroglutamate Aβ in Down Syndrome and Sporadic Alzheimer’s Disease

Frontiers in Aging Neuroscience(2021)10.3389/fnagi.2021.728739

N/A

0.292DataRank · unranked

6 citations

Tamara Racic, Eric E. Abrahamson, Victor L. Villemagne, Benjamin L. Handen, Ira T. Lott +3 more

Longitudinal changes in white matter hyperintensity volume accelerate across the Alzheimer's continuum in adults with Down syndrome

Alzheimer s & Dementia(2025)10.1002/alz.70679

Top 57%

0.283DataRank

Top 57%5 citations

Natalie Edwards, Lisi Flores Aguilar, Mohamad J. Alshikho, Anna Smith, Rachel LeMay +13 more

Alzheimer's disease diagnostic progression is associated with cerebrovascular disease and neuroinflammation in adults with Down syndrome

Alzheimer s & Dementia(2025)10.1002/alz.70726

N/A

0.241DataRank · unranked

4 citations

Patrick J. Lao, Mohamad J. Alshikho, Olivia M. Ericsson, Batool Rizvi, Melissa Petersen +20 more

U1‐70K and U1A and tau pathogenesis in demented and non‐demented individuals with Down syndrome

Alzheimer s & Dementia(2025)10.1002/alz.70474

N/A

0.208DataRank · unranked

3 citations

Jennifer C. Miguel, Muhammad Nadeem, Michael Malek‐Ahmadi, Chadwick M. Hales, Elizabeth Head +2 more

Cholinotrophic basal forebrain connectome dysfunction in Down syndrome with and without dementia

iScience(2025)10.1016/j.isci.2025.113041

N/A

0.165DataRank · unranked

2 citations

Sylvia E. Perez, Muhammad Nadeem, Elizabeth Head, Elliott J. Mufson, Marta Moreno‐Rodríguez

The tau biomarker cascade is condensed in Down syndrome compared with sporadic Alzheimer’s disease

Brain(2025)10.1093/brain/awaf428

N/A

0.165DataRank · unranked

2 citations

Hailey Bruzzone, Karly Alex Cody, Jacob Morse, Rachael E. Wilson, Brecca Bettcher +65 more

Neuropathology of trisomy 21 mosaicism in a case with early‐onset dementia

Alzheimer s & Dementia(2024)10.1002/alz.14394

N/A

0.104DataRank · unranked

1 citations

Jesse R. Pascual, Sierra Wright, Christopher Kwesi O. Williams, Shino Magaki, William H. Yong +4 more

UC Irvine’s Brain Initiative Cell Atlas Network (BICAN) Brain Procurement Program for the Center for Multiomic Human Brain Cell Atlas Project

bioRxiv (Cold Spring Harbor Laboratory)(2025)10.64898/2025.12.23.696304

Top 78%

0.104DataRank

Top 78%1 citations

Bryan M Tran, Ginny Wu, Zhiqun Tan, Elizabeth Mendoza, Miyoung Kim +44 more

Innovating Therapies for Down Syndrome: An International Virtual Conference of the T21 Research Society

Molecular Syndromology(2022)10.1159/000526021

N/A

0.104DataRank · unranked

1 citations

Lisi Flores Aguilar, Benjamin L. Handen, Marie‐Claude Potier, Ann‐Charlotte Granholm, Stephanie L. Sherman +8 more

“Being brave, being seen, and having your voice heard”: Perspectives of self‐advocates and families toward accessible and impactful research of Alzheimer's disease in down syndrome

Alzheimer s & Dementia(2025)10.1002/alz.70999

N/A

0.104DataRank · unranked

1 citations

Lauren Ptomey, Elizabeth Head, Ann Cohen, Joseph Mike Briones, Henry Shaw +16 more

Iron‐associated lipid peroxidation in Alzheimer's disease is increased in lipid rafts with decreased ferroptosis suppressors, tested by chelation in mice

Alzheimer s & Dementia(2025)10.1002/alz.14541

N/A

0DataRank · unranked

29 citations

José A. Godoy-Lugo, Gilberto Garcia, Justine Silva, Minhoo Kim, Amy Christensen +10 more

Common neuropathologic change drivers of hippocampal sclerosis of ageing

Brain(2025)10.1093/brain/awaf158

N/A

0DataRank · unranked

9 citations

Jicheng Lou, William H. Yong, Elizabeth Head, María M. Corrada, Peter T. Nelson +2 more

Regional differences in astrocytic Aquaporin-4 protein levels and distribution in aging and Alzheimer's disease in down syndrome

Neurobiology of Disease(2025)10.1016/j.nbd.2025.107114

N/A

0DataRank · unranked

7 citations

Haley Miyasato, Kevin Camey, Krina A Ghadia, Elizabeth J. Andrews, Phong Ngo +17 more

A neuropathology case report of a woman with Down syndrome who remained cognitively stable: Implications for resilience to neuropathology

Alzheimer s & Dementia(2025)10.1002/alz.14479

N/A

0DataRank · unranked

14 citations

Jerry J. Lou, Lisi Flores Aguilar, Jamie Nakagiri, William H. Yong, Christy Hom +19 more

Resistance and resilience to Alzheimer's disease in Down syndrome

Alzheimer s & Dementia(2025)10.1002/alz.70151

N/A

0DataRank · unranked

13 citations

Elouise A. Koops, Beau M. Ances, Elizabeth J. Andrews, Eider M. Arenaza‐Urquijo, Alexandre Bejanin +40 more

Apolipoprotein E abundance is elevated in the brains of individuals with Down syndrome–Alzheimer’s disease

Acta Neuropathologica(2025)10.1007/s00401-025-02889-0

N/A

0DataRank · unranked

8 citations

Yazead Buhidma, Paige Mumford, Wendy Heywood, Jenny Hällqvist, Lisi Flores Aguilar +11 more

Late‐life emergence of neuropsychiatric symptoms and risk of cognitive impairment in cognitively unimpaired individuals

Alzheimer s & Dementia(2025)10.1002/alz.70619

N/A

0DataRank · unranked

6 citations

Elizabeth Head, Craig E.L. Stark, Lorena Sordo, Katharine A. Kirby, Maria G. Corona +4 more

PET‐measured amyloid beta accumulates at an accelerated rate in Down syndrome compared to neurotypical populations

Alzheimer s & Dementia(2025)10.1002/alz.70357

N/A

0DataRank · unranked

4 citations

Alexandra H DiFilippo, Max McLachlan, Brecca Betcher, Matthew Zammit, Tobey J. Betthauser +20 more

Age and sex are associated with Alzheimer's disease neuropathology in Down syndrome

Alzheimer s & Dementia(2025)10.1002/alz.70408

N/A

0DataRank · unranked

4 citations

Phong Ngo, Jesse R. Pascual, Freddy Gonzalez, Michael Phelan, Sierra Wright +9 more

Examination of metabolic syndrome in Down syndrome and association with dementia

Alzheimer s & Dementia(2025)10.1002/alz.70799

N/A

0DataRank · unranked

3 citations

Lam‐Ha T. Dang, Laura Xicota, Sharon J. Krinsky‐McHale, Balaji Kannappan, Adam M. Brickman +8 more

Single-nucleus multi-omics identifies shared and distinct pathways in Pick’s and Alzheimer’s disease

Science Advances(2025)10.1126/sciadv.ads7973

N/A

0DataRank · unranked

3 citations

Sudeshna Das, Samuel Morabito, Jennifer Stocksdale, Emily Miyoshi, Shushrruth Sai Srinivasan +10 more

Gait variability as a marker of white matter integrity in individuals with Down syndrome

Alzheimer s & Dementia(2025)10.1002/alz.70407

N/A

0DataRank · unranked

2 citations

David K. Powell, Amanda C. Glueck, Elizabeth Head, Moaz W. Ibrahim, Amelia J. Anderson‐Mooney +5 more

Celebrating neuropathology's contributions to Alzheimer's Disease Research Centers

Alzheimer s & Dementia(2025)10.1002/alz.70734

N/A

0DataRank · unranked

4 citations

Lea T. Grinberg, Jared T. Ahrendsen, Thomas G. Beach, Kevin F. Bieniek, Rudolph J. Castellani +41 more

Longitudinal diffusion tensor imaging correlates with amyloid burden in Down syndrome

Alzheimer s & Dementia(2025)10.1002/alz.70572

N/A

0DataRank · unranked

2 citations

José Guerrero-González, Andrew K McVea, Matthew Zammit, Steven Kecskemeti, Sigan L. Hartley +7 more

A comparison of multiple amyloid PET radiotracers for Down syndrome clinical trials

Brain Communications(2025)10.1093/braincomms/fcaf406

N/A

0DataRank · unranked

2 citations

Julie C. Price, Bradley T. Christian, Michael S. Rafii, Beau M. Ances, Howard Andrews +51 more

Imaging and plasma biomarkers for pathological accumulation in Down syndrome

Brain(2025)10.1093/brain/awaf418

N/A

0DataRank · unranked

2 citations

Ziqiao Jiao, James T. Kennedy, Ann D. Cohen, Zinayida Schlachetzki, Melissa Petersen +21 more

SARS-CoV-2 infection of human cortical cells is influenced by the interaction between aneuploidy and biological sex: insights from a Down syndrome in vitro model

Acta Neuropathologica(2025)10.1007/s00401-025-02895-2

N/A

0DataRank · unranked

2 citations

Evgueni A. Sevrioukov, Gema M. Olivarria, Lauren Hitchcock, Dominic I. Javonillo, Sydney M. Campos +10 more

Increase of brain Aβ peptides and secretase activity during normal aging in rodent and human

GeroScience(2025)10.1007/s11357-025-01926-w

N/A

0DataRank · unranked

1 citations

Max A. Thorwald, Elizabeth Head, Ashley Gomm, Can Zhang, Rudolph E. Tanzi +2 more

Development of Molecular Neuropathology in Down Syndrome across the Lifespan

Journal of Neuroscience(2025)10.1523/jneurosci.1365-25.2025

N/A

0DataRank · unranked

1 citations

Luis de la Torre-Ubieta, Ying Zhu, Elizabeth Head, Vivek Swarup, André M. M. Sousa +1 more

Proteome Signature of Alzheimer-Like Phenotypes in Frontal Cortices From Young and Old Individuals With Down Syndrome

Molecular Neurobiology(2025)10.1007/s12035-025-05432-0

N/A

0DataRank · unranked

1 citations

Viviana Greco, Antonella Tramutola, Monika Rataj-Baniowska, Eugenio Barone, Chiara Lanzillotta +9 more

A randomized clinical trial reveals effects of mindfulness and slow breathing on plasma amyloid beta levels

medRxiv(2025)10.1101/2025.03.10.25323695

N/A

0DataRank · unranked

2 citations

B. Rael Cahn, Paul D. Choi, Hye Rynn J. Lee, Shaakhini Satchi, Jungwon Min +8 more

Applying machine learning to assist in the morphometric assessment of brain arteriolosclerosis through automation

PubMed(2025)10.17879/freeneuropathology-2025-6387

N/A

0DataRank · unranked

0 citations

Peter Chang, Kiana Nava, Chanon Chantaduly, Hsin-Pei Wang, William H. Yong +14 more

Genome‐wide association analyses identify candidate loci for amyloid imaging and plasma biomarkers in adults with Down syndrome

Alzheimer s & Dementia(2025)10.1002/alz.70358

N/A

0DataRank · unranked

0 citations

Lam‐Ha T. Dang, Ruyu Shi, Kang-Hsien Fan, Asma Naseer Cheema, Laura Xicota +16 more

Alzheimer's Disease Research Center Down Syndrome Cores: Experience from two sites

Alzheimer s & Dementia(2025)10.1002/alz.70612

N/A

0DataRank · unranked

0 citations

Christy Hom, Heather Wilkins, Eric Doran, Sierra Wright, Dan Hoang +8 more

Blood pressure dynamic instability and neurodegeneration in older adults

Journal of Alzheimer s Disease(2025)10.1177/13872877251386443

N/A

0DataRank · unranked

0 citations

Fatemah Shenasa, Isabel J. Sible, Arunima Kapoor, Allison C Engstrom, Shubir Dutt +8 more

Hippocampal 1H-MR spectroscopy metabolites are linked to CSF tau pathology in cognitively unimpaired older adults along the Alzheimer’s continuum

Neurobiology of Aging(2025)10.1016/j.neurobiolaging.2025.10.005

N/A

0DataRank · unranked

0 citations

Casey R. Vanderlip, Sierra Wright, Lorena Sordo, Elizabeth Head, Craig E.L. Stark +1 more

Neuropsychiatric symptoms and emerging dementia in people with Down syndrome and older adults

Alzheimer s & Dementia(2025)10.1002/alz.70871

N/A

0DataRank · unranked

0 citations

Daniel L. Gillen, Christy Hom, Lidio Jaimes, Srisai Saavarni Chilukuri, Noah McMahon +7 more

Low frequency BOLD oscillations, APOE4, and plasma pTau217

medRxiv(2025)10.1101/2025.11.25.25340991

N/A

0DataRank · unranked

0 citations

Arunima Kapoor, Allison C Engstrom, Jillian L. Joyce, Melanie Quiring, John Paul M Alitin +10 more

The Alzheimer's Biomarker Consortium‐Down Syndrome: Rationale and methodology

Alzheimer s & Dementia Diagnosis Assessment & Disease Monitoring(2020)10.1002/dad2.12065

N/A

0DataRank · unranked

122 citations

Ira T. Lott, Bradley T. Christian, Nicole Schupf, Sid E. O’Bryant, Mark Mapstone +17 more

Blood‐brain barrier integrity and vessel morphology in adults with Down syndrome and Alzheimer's neuropathology

Alzheimer s & Dementia(2025)10.1002/alz70855_106199

N/A

0DataRank · unranked

0 citations

Jesse R. Pascual, Halyma Nguyen, Annie Du, Natalie C. Edwards, Patrick J. Lao +9 more

Chronic PERK induction promotes Alzheimer-like neuropathology in Down syndrome: Insights for therapeutic intervention

Progress in Neurobiology(2020)10.1016/j.pneurobio.2020.101892

N/A

0DataRank · unranked

44 citations

Ilaria Zuliani, Antonella Tramutola, Eugenio Barone, Carla Blarzino, Valentina Folgiero +10 more

A preliminary study of cerebral blood flow, aging and dementia in people with Down syndrome

Journal of Intellectual Disability Research(2020)10.1111/jir.12784

N/A

0DataRank · unranked

13 citations

Kathryn L. Van Pelt, Ai-Ling Lin, Nathan F. Johnson, Gregory A. Jicha, Allison Caban‐Holt +6 more

APOE genotype-dependent pharmacogenetic responses to rapamycin for preventing Alzheimer's disease

Neurobiology of Disease(2020)10.1016/j.nbd.2020.104834

N/A

0DataRank · unranked

44 citations

Ishita Parikh, Lucille M. Yanckello, Renee S. White, Anika M. S. Hartz, Chase E. Taylor +9 more

Metabolic correlates of prevalent mild cognitive impairment and Alzheimer's disease in adults with Down syndrome

Alzheimer s & Dementia Diagnosis Assessment & Disease Monitoring(2020)10.1002/dad2.12028

N/A

0DataRank · unranked

23 citations

Thomas Groß, Fabìo Macciardi, Amrita K. Cheema, Melissa Petersen, Elizabeth Head +7 more

Diagnostic and prognostic performance and longitudinal changes in plasma neurofilament light chain concentrations in adults with Down syndrome: a cohort study

The Lancet Neurology(2021)10.1016/s1474-4422(21)00129-0

N/A

0DataRank · unranked

64 citations

Daniel Alcolea, Isabel Barroeta, Laura Videla, Laia Muñoz, Kathyrn L Van Pelt +20 more

Impact of increased APP gene dose in Down syndrome and the Dp16 mouse model

Alzheimer s & Dementia(2021)10.1002/alz.12463

N/A

0DataRank · unranked

61 citations

Cassia Overk, Ann Becker, Dominique Derse, Ricardo Albay, Kim Weldy +7 more

Tacrolimus Protects against Age-Associated Microstructural Changes in the Beagle Brain

Journal of Neuroscience(2021)10.1523/jneurosci.0361-21.2021

N/A

0DataRank · unranked

32 citations

Margo F. Ubele, Stephanie M. Krumholz, Kathy Boaz, Jennifer L. Mefford, Erin D. Jones +8 more

Type I Interferon Signaling Drives Microglial Dysfunction and Senescence in Human iPSC Models of Down Syndrome and Alzheimer’s Disease

bioRxiv (Cold Spring Harbor Laboratory)(2021)10.1101/2021.12.22.473858

N/A

0DataRank · unranked

1 citations

Ranjie Xu, Le Wang, Mahabub Alam, Ziyuan Ma, Sining Zhu +11 more

Markers of early changes in cognition across cohorts of adults with Down syndrome at risk of Alzheimer's disease.

Apollo (University of Cambridge)(2021)10.17863/cam.71177

N/A

0DataRank · unranked

0 citations

R. Asaad Baksh, Bessy Benejam, Jessica Beresford‐Webb, Antonia Coppus, Juan Fortea +14 more

Type-I-interferon signaling drives microglial dysfunction and senescence in human iPSC models of Down syndrome and Alzheimer’s disease

Cell stem cell(2022)10.1016/j.stem.2022.06.007

N/A

0DataRank · unranked

167 citations

Ranjie Xu, Le Wang, Mahabub Alam, Ziyuan Ma, Sining Zhu +11 more

Conducting clinical trials in persons with Down syndrome: summary from the NIH INCLUDE Down syndrome clinical trials readiness working group

Journal of Neurodevelopmental Disorders(2022)10.1186/s11689-022-09435-z

N/A

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40 citations

Mara L. Becker, George T. Capone, Kathleen M. Egan, Juan Fortea, Benjamin L. Handen +7 more

Amyloid futures in the expanding pathology of brain aging and dementia

Alzheimer s & Dementia(2022)10.1002/alz.12896

N/A

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32 citations

Justine Silva, Elizabeth Head, Caleb E. Finch, Max A. Thorwald

Blood pressure variability and plasma Alzheimer’s disease biomarkers in older adults

Scientific Reports(2022)10.1038/s41598-022-20627-4

N/A

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25 citations

Belinda Yew, Jung Yun Jang, John Paul M Alitin, Yanrong Li, Aimée Gaubert +13 more

Reduced synaptic proteins and SNARE complexes in Down syndrome with Alzheimer's disease and the Dp16 mouse Down syndrome model: Impact of APP gene dose

Alzheimer s & Dementia(2022)10.1002/alz.12835

N/A

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21 citations

Xinxin Zuo, Ann Becker, Elizabeth Head, William C. Mobley, Xu‐Qiao Chen

Impact of the COVID-19 pandemic on daily life, mood, and behavior of adults with Down syndrome

Disability and health journal(2022)10.1016/j.dhjo.2022.101278

N/A

0DataRank · unranked

20 citations

Victoria Fleming, Brianna Piro‐Gambetti, Annie Cohen, Beau M. Ances, Michael A. Yassa +13 more

Weight Loss and Alzheimer’s Disease in Down Syndrome

Journal of Alzheimer s Disease(2022)10.3233/jad-220865

N/A

0DataRank · unranked

12 citations

Brian C. Helsel, Lauren T. Ptomey, H. Diana Rosas, Benjamin L. Handen, Charles M. Laymon +10 more

Probing the proteome to explore potential correlates of increased Alzheimer's‐related cerebrovascular disease in adults with Down syndrome

Alzheimer s & Dementia(2022)10.1002/alz.12627

N/A

0DataRank · unranked

12 citations

Melissa Petersen, Fan Zhang, Patrick J. Lao, Molly E. Zimmerman, Yian Gu +19 more

Characterization of hippocampal sclerosis of aging and its association with other neuropathologic changes and cognitive deficits in the oldest-old

Acta Neuropathologica(2023)10.1007/s00401-023-02606-9

N/A

0DataRank · unranked

36 citations

Tianchen Qian, Syed Bukhari, Katelynn M. Nguyen, Davis C. Woodworth, Elizabeth Head +5 more

Antibodies Raised Against an Aβ Oligomer Mimic Recognize Pathological Features in Alzheimer’s Disease and Associated Amyloid-Disease Brain Tissue

ACS Central Science(2023)10.1021/acscentsci.3c00592

N/A

0DataRank · unranked

18 citations

Chelsea Marie T. Parrocha, Sepehr Haerianardakani, Gretchen Guaglianone, Jennifer Nguyen, Michelle N. Diab +5 more

Plasma NT1‐tau and Aβ42 correlate with age and cognitive function in two large Down syndrome cohorts

Alzheimer s & Dementia(2023)10.1002/alz.13382

N/A

0DataRank · unranked

9 citations

Kathryn L. Van Pelt, Lei Liu, Amirah K. Anderson, Beth L. Ostaszewski, Mark Mapstone +8 more

Enlarged perivascular spaces and plasma Aβ42/Aβ40 ratio in older adults without dementia

Neurobiology of Aging(2023)10.1016/j.neurobiolaging.2023.04.004

N/A

0DataRank · unranked

10 citations

Aimée Gaubert, Belinda Yew, Jung Yun Jang, Shubir Dutt, Yanrong Li +12 more

Cerebrovascular disease drives Alzheimer plasma biomarker concentrations in adults with Down syndrome

medRxiv(2023)10.1101/2023.11.28.23298693

N/A

0DataRank · unranked

10 citations

Patrick J. Lao, Mohamad J. Alshikho, Olivia M. Ericsson, Batool Rizvi, Melissa Petersen +20 more

Plasma NT1-tau and Aβ 42 correlate with age and cognitive function in two large Down syndrome cohorts

medRxiv(2023)10.1101/2023.03.10.23287109

N/A

0DataRank · unranked

2 citations

Kathryn L. Van Pelt, Lei Liu, Amirah K. Anderson, Beth L. Ostaszewski, Mark Mapstone +8 more

Pathways linking pulse pressure to dementia in adults with Down syndrome

medRxiv(2023)10.1101/2023.10.26.23297625

N/A

0DataRank · unranked

0 citations

Patrick J. Lao, Mithra Sathishkumar, Lisa Taylor, Nazek Queder, Liv McMillan +17 more

Cerebrovascular disease emerges with age and Alzheimer’s disease in adults with Down syndrome

Scientific Reports(2024)10.1038/s41598-024-61962-y

N/A

0DataRank · unranked

28 citations

Natalie Edwards, Lisi Flores Aguilar, Mohamad J. Alshikho, Batool Rizvi, Dana Tudorascu +11 more

Central autonomic network dysfunction and plasma Alzheimer’s disease biomarkers in older adults

Alzheimer s Research & Therapy(2024)10.1186/s13195-024-01486-9

N/A

0DataRank · unranked

21 citations

Arunima Kapoor, Allison C Engstrom, Fatemah Shenasa, John Paul M Alitin, Aimée Gaubert +9 more

Blood biomarkers in Down syndrome: Facilitating Alzheimer's disease detection and monitoring

Alzheimer s & Dementia(2024)10.1002/alz.14364

N/A

0DataRank · unranked

17 citations

Lisi Flores Aguilar, Elizabeth Head, Laia Montoliu‐Gaya, André Strydom, Sarah E. Pape +9 more

Down Syndrome Biobank Consortium: A perspective

Alzheimer s & Dementia(2024)10.1002/alz.13692

N/A

0DataRank · unranked

17 citations

Isabel Barroeta, Steven L. Carroll, Juan Fortea, Anah Gilmore, Stephen D. Ginsberg +14 more

Whole genome‐wide sequence analysis of long‐lived families (Long‐Life Family Study) identifies MTUS2 gene associated with late‐onset Alzheimer's disease

Alzheimer s & Dementia(2024)10.1002/alz.13718

N/A

0DataRank · unranked

17 citations

Stephanie Cosentino, Badri N. Vardarajan, Richard Mayeux, Thomas T. Perls, Stacy L. Andersen +14 more

Cognitive and functional performance and plasma biomarkers of early Alzheimer's disease in Down syndrome

Alzheimer s & Dementia Diagnosis Assessment & Disease Monitoring(2024)10.1002/dad2.12582

N/A

0DataRank · unranked

16 citations

Benjamin L. Handen, Melissa Petersen, Sid E. O’Bryant, Jamie C. Peven, Dana Tudorascu +17 more

Neuropathological findings in Down syndrome, Alzheimer’s disease and control patients with and without SARS-COV-2: preliminary findings

Acta Neuropathologica(2024)10.1007/s00401-024-02743-9

N/A

0DataRank · unranked

8 citations

Elisabet Englund, Anah Gilmore, Elizabeth Head, William H. Yong, Sylvia E. Perez +4 more

Age-Related Brain Atrophy and the Positive Effects of Behavioral Enrichment in Middle-Aged Beagles

Journal of Neuroscience(2024)10.1523/jneurosci.2366-23.2024

N/A

0DataRank · unranked

5 citations

Hamsanandini Radhakrishnan, Margo F. Ubele, Kathy Boaz, Jennifer L. Mefford, Erin D. Jones +14 more

Calcineurin/NFAT inhibitors maintain cognition in a preclinical prevention study in an aging canine model of Alzheimer disease

Neurobiology of Aging(2024)10.1016/j.neurobiolaging.2024.11.003

N/A

0DataRank · unranked

4 citations

Margo F. Ubele, Kathy Boaz, Jennifer L. Mefford, Erin Dehnart Jones, Katie McCarty +15 more

A pathway linking pulse pressure to dementia in adults with Down syndrome

Brain Communications(2024)10.1093/braincomms/fcae157

N/A

0DataRank · unranked

3 citations

Patrick J. Lao, Mithra Sathishkumar, Lisa Taylor, Nazek Queder, Liv McMillan +17 more

Locus coeruleus MRI contrast, cerebral perfusion, and plasma Alzheimer’s disease biomarkers in older adults

Neurobiology of Aging(2024)10.1016/j.neurobiolaging.2024.11.008

N/A

0DataRank · unranked

1 citations

Shelby L. Bachman, Martin J. Dahl, Yanrong Li, Belinda Yew, Jung Yun Jang +20 more

Unique Pathology in the Locus Coeruleus of Individuals with Down Syndrome

Journal of Alzheimer s Disease(2024)10.3233/jad-240043

N/A

0DataRank · unranked

2 citations

Eric D. Hamlett, Samuel Guzman, Elizabeth Head, Ann‐Charlotte Granholm, Aurélie Ledreux +1 more

A Trisomy 21-linked Hematopoietic Gene Variant in Microglia Confers Resilience in Human iPSC Models of Alzheimer’s Disease

bioRxiv (Cold Spring Harbor Laboratory)(2024)10.1101/2024.03.12.584646

N/A

0DataRank · unranked

5 citations

Ziyuan Ma, Rui Dang, Haiwei Zhang, Rachael Kim, Haipeng Xue +6 more

Single-nucleus multi-omics identifies shared and distinct pathways in Pick’s and Alzheimer’s disease

bioRxiv (Cold Spring Harbor Laboratory)(2024)10.1101/2024.09.06.611761

N/A

0DataRank · unranked

4 citations

Sudeshna Das, Samuel Morabito, Jennifer Stocksdale, Emily Miyoshi, Shushrruth Sai Srinivasan +10 more

Spontaneous cerebrovascular reactivity at rest in older adults with and without mild cognitive impairment and memory deficits

medRxiv(2024)10.1101/2024.06.18.24309109

N/A

0DataRank · unranked

2 citations

John Paul M Alitin, Arunima Kapoor, Shubir Dutt, Trevor Lohman, Isabel J. Sible +13 more

Increased fibrin deposition in the brains of individuals with Down syndrome and Alzheimer’s disease

Alzheimer s & Dementia(2024)10.1002/alz.089882

N/A

0DataRank · unranked

0 citations

Lisi Flores Aguilar, Natalie C. Edwards, Patrick J. Lao, Jae Kyu Ryu, Katerina Akassoglou +7 more

Elizabeth Head

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