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Covalent Complex of DNA and Bacterial Topoisomerase: Implications in Antibacterial Drug Development

ChemMedChem(2020)10.1002/cmdc.201900721Source: DataRank Database

Covalent Complex of DNA and Bacterial Topoisomerase: Implications in Antibacterial Drug Development is a research paper published in ChemMedChem (2020). On theSindex it has a DataRank of 0. It has been cited 21 times.

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0DataRank · unranked

Scored on demand from live citation data

Open Access21 citations

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›Methodology & internals

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Pipeline:MetadataData-paper checkEnrichmentCitation networkScoring

Enrichment:Funding (6 grants)Impact (FWCI 0.75)OA: greenTopics (50)IDs (PubMed, PMC, OpenAlex)Annotations (1)SDGs (1)

FAIR Checklist

Context only (not used in score)

Findable (1/2)

Has DOI

Accessible (1/2)

Open Access

Interoperable (0/2)

Reusable (0/3)

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Authors (6)

Prem P. Chapagain ORCID,Ahmed Seddek ORCID,Thirunavukkarasu Annamalai,Aykut Üren ORCID,Yuk‐Ching Tse‐Dinh ORCID

Live enrichment

PubMed:32043806 PMC:PMC7133791 OpenAlex:https://openalex.org/W3005694025

National Institutes of Health

Grant: P30CA51008

National Institutes of Health

Grant: R01GM054226

NCI NIH HHS

Grant: P30 CA051008

National Institutes of Health

Grant: 5R01GM054226-04

CONTROL OF DNA TOPOLOGY

National Institutes of Health

Grant: 3P30CA051008-16S1

CANCER CENTER SUPPORT GRANT

Georgetown University

FWCI

0.75

Citation Percentile

0.7%

Citation Trend

2021

2022

2023

2024

2025

2026

greenLicense: Wiley Online Library User Agreement

repositoryhttps://www.ncbi.nlm.nih.gov/pmc/articles/7133791

publisherhttps://api.wiley.com/onlinelibrary/tdm/v1/articles/10.1002%2Fcmdc.201900721

publisherhttps://onlinelibrary.wiley.com/doi/pdf/10.1002/cmdc.201900721

publisherhttps://onlinelibrary.wiley.com/doi/full-xml/10.1002/cmdc.201900721

Fields of Study

Cancer therapeutics and mechanismsNeutropenia and Cancer InfectionsAntibiotics Pharmacokinetics and Efficacy0301 basic medicine03 medical and health sciencesAnti-Bacterial AgentsDNA Topoisomerases, Type IDNA, BacterialDrug DevelopmentEscherichia coliMolecular Dynamics SimulationTopoisomerase I Inhibitors

MeSH Terms

Drug DevelopmentAnti-Bacterial AgentsDNA Topoisomerases, Type IDNA, BacterialEscherichia coliMolecular Dynamics SimulationTopoisomerase I Inhibitors

Keywords

TopoisomeraseDruggabilityTernary complexDNACovalent bondMolecular dynamicsEscherichia coliChemistryTopoisomerase IVAntibacterial activityBiochemistryBiophysicsCombinatorial chemistryDNA gyraseBiologyStereochemistryEnzymeComputational chemistryBacteriaGeneticsSurface plasmon resonanceMD simulationAntibacterial drugsTopoisomerase InhibitorsTopoisomerase-dna Covalent ComplexDNA, BacterialMolecular Dynamics SimulationAnti-Bacterial AgentsDNA Topoisomerases, Type IDrug DevelopmentTopoisomerase I Inhibitors

Sustainable Development Goals

SDG 0: Good health and well-being