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Improvement of motor and behavioral activity in Sandhoff mice transplanted with human CD34+ cells transduced with a HexA/HexB expressing lentiviral vector

The Journal of Gene Medicine(2020)10.1002/jgm.3205Source: DataRank Database

Improvement of motor and behavioral activity in Sandhoff mice transplanted with human CD34+ cells transduced with a HexA/HexB expressing lentiviral vector is a research paper published in The Journal of Gene Medicine (2020). On theSindex it has a DataRank of 0. It has been cited 16 times.

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0DataRank · unranked

Scored on demand from live citation data

Open Access16 citations

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›Methodology & internals

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Pipeline:MetadataData-paper checkEnrichmentCitation networkScoring

Enrichment:Funding (7 grants)Impact (FWCI 1.21)OA: greenTopics (42)IDs (PubMed, PMC, OpenAlex)SDGs (1)

FAIR Checklist

Context only (not used in score)

Findable (1/2)

Has DOI

Accessible (1/2)

Open Access

Interoperable (0/2)

Reusable (0/3)

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Authors (5)

Kyle Hendrix,Haley Maciel,Jan A. Nolta ORCID,Joseph S. Anderson ORCID,Julie R. Beegle

Live enrichment

PubMed:32335981 PMC:PMC12067969 OpenAlex:https://openalex.org/W3019238288

California Institute for Regenerative Medicine

Grant: EDUC2‐08397

California Institute for Regenerative Medicine

Grant: TRAN1‐08519

National Center for Advancing Translational Sciences

Grant: UL1 TR001860 and KL2 TR001859

NIH HHS

Grant: R24 OD021606

NCRR NIH HHS

Grant: S10 RR026825

NCATS NIH HHS

Grant: UL1 TR001860

NCATS NIH HHS

Grant: KL2 TR001859

FWCI

1.21

Citation Percentile

0.8%

Citation Trend

2021

2022

2023

2024

2025

greenLicense: http://onlinelibrary.wiley.com/termsAndConditions#vor

repositoryhttps://www.ncbi.nlm.nih.gov/pmc/articles/12067969

publisherhttps://onlinelibrary.wiley.com/doi/pdf/10.1002/jgm.3205

publisherhttps://onlinelibrary.wiley.com/doi/full-xml/10.1002/jgm.3205

journalhttps://doi.org/10.1002/jgm.3205

Fields of Study

Lysosomal Storage Disorders ResearchVirus-based gene therapy researchTransgenic Plants and Applications

MeSH Terms

AnimalsBehavior, AnimalDisease Models, AnimalGenetic VectorsHematopoietic Stem CellsHumansInterleukin-2Motor ActivitySandhoff DiseaseTay-Sachs DiseaseLentivirusMice, Inbred NODHematopoietic Stem Cell TransplantationHomeodomain ProteinsAntigens, CD34Micebeta-Hexosaminidase alpha Chainbeta-Hexosaminidase beta Chain

Keywords

Sandhoff diseaseBiologyGenetic enhancementStem cellMetachromatic leukodystrophyHEXAViral vectorHaematopoiesisProgenitor cellImmunologyKrabbe diseaseCell biologyLeukodystrophyMedicineInternal medicineGeneticsDiseaseBiochemistryGeneTherapyHemopoietic

Sustainable Development Goals

SDG 0: Good health and well-being