A brief overview of amyloids and Alzheimer's disease is a research paper published in Protein Science (2014). On theSindex it has a DataRank of 5.0. It has been cited 169 times, with 169 citing works in its 1-hop citation network.
AbstractAmyloid fibrils are self‐assembled fibrous protein aggregates that are associated with a number of presently incurable diseases such as Alzheimer's and Parkinson's disease. Millions of people worldwide suffer from amyloid diseases. This review summarizes the unique cross‐β structure of amyloid fibrils, morphological variations, the kinetics of amyloid fibril formation, and the cytotoxic effects of these fibrils and oligomers. Alzheimer's disease is also explored as an example of an amyloid disease to show the various approaches to treat these amyloid diseases. Finally, this review investigates the nanotechnological and biological applications of amyloid fibrils; as well as a summary of the typical biological pathways involved in the disposal of amyloid fibrils and their precursors.
FAIR checklist signals are shown for context only and do not affect DataRank scoring.
Base Score Contribution
0.770
From this paper's citation signal
Citation Network Contribution
4.2
From 139 citing papers with measurable signal
DataRank blends this paper's own citation count with the influence of the papers that cite it. Here, roughly 15% comes from its base citations and 85% from the citation network (139 citing papers contributed measurable signal).
Citers are pulled from OpenAlex sorted by cited_by_count:descand capped per paper, so when the cap binds we keep the highest-signal references and the score is reproducible across reruns.
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