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N3A motifs in RIβ mediate allosteric crosstalk between cAMP and ATP in PKA activation

Protein Science(2025)10.1002/pro.70332Source: DataRank Database

N3A motifs in RIβ mediate allosteric crosstalk between cAMP and ATP in PKA activation is a research paper published in Protein Science (2025). On theSindex it has a DataRank of 0. It has been cited 1 time.

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0DataRank · unranked

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Open Access1 citations

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›Methodology & internals

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Pipeline:MetadataData-paper checkEnrichmentCitation networkScoring

Enrichment:Funding (6 grants)Impact (FWCI 0.42)OA: hybridTopics (40)IDs (PubMed, OpenAlex)

FAIR Checklist

Context only (not used in score)

Findable (1/2)

Has DOI

Accessible (1/2)

Open Access

Interoperable (0/2)

Reusable (0/3)

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Authors (7)

Jessica Bruystens,PK Sahoo,José Bubis ORCID,Rodrigo A. Maillard ORCID,Susan S. Taylor ORCID

Live enrichment

PubMed:41108566 OpenAlex:https://openalex.org/W4415313908

National Institutes of Health

Grant: GM130389

Israel Science Foundation

Grant: 1706/22

Israel Cancer Research Fund

Grant: 22‐203‐RCDA

Israel Cancer Research Fund

Grant: 22-203-RCDA

United States-Israel Binational Science Foundation

Grant: 2023105

NIGMS NIH HHS

Grant: R35 GM130389

FWCI

0.42

Citation Percentile

0.6%

Citation Trend

2026

hybridLicense: cc-by

journalhttps://onlinelibrary.wiley.com/doi/pdfdirect/10.1002/pro.70332

publisherhttps://onlinelibrary.wiley.com/doi/pdfdirect/10.1002/pro.70332

publisherhttps://onlinelibrary.wiley.com/doi/pdf/10.1002/pro.70332

journalhttps://doi.org/10.1002/pro.70332

repositoryhttps://pubmed.ncbi.nlm.nih.gov/41108566

Fields of Study

Protein Kinase Regulation and GTPase SignalingRNA Research and SplicingRNA and protein synthesis mechanismsAdenosine TriphosphateCyclic AMPCyclic AMP-Dependent Protein Kinase RIIbeta SubunitAllosteric RegulationHumansAmino Acid MotifsCyclic AMP-Dependent Protein KinasesModels, MolecularA Kinase Anchor ProteinsEnzyme ActivationAnimalsCrystallography, X-Ray

MeSH Terms

Cyclic AMPAdenosine TriphosphateAllosteric RegulationAnimalsEnzyme ActivationHumansModels, MolecularCyclic AMP-Dependent Protein KinasesCrystallography, X-RayAmino Acid MotifsCyclic AMP-Dependent Protein Kinase RIIbeta SubunitA Kinase Anchor Proteins

Keywords

Protein subunitAllosteric regulationCrosstalkLinkerProtein kinase AProtein kinase domainKinaseProtein structureStructural motifPKAPRKAR1Bheterodimer structureholoenzyme