Susan S. Taylor

Also affiliated with University of California San Diego

Biochemistry, Genetics and Molecular BiologyMaterials ScienceComputer Science

Pilot corpus only

This score is computed over theSindex pilot corpus and does not cover the full scientific literature. Scores are relative to papers we have ingested — papers, authors, and institutions outside the pilot are not represented. Methodology.

Top 100%percentile

0Author DataRank

Indexed papers

0in pilot corpus

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Papers

Driven by 57 papers. Top paper: “Gαs–Protein Kinase A (PKA) Pathway Signalopathies: The Emerging Genetic Landscape and Therapeutic Potential of Human Diseases Driven by Aberrant Gαs-PKA Signaling”.

Gαs–Protein Kinase A (PKA) Pathway Signalopathies: The Emerging Genetic Landscape and Therapeutic Potential of Human Diseases Driven by Aberrant Gαs-PKA Signaling

Pharmacological Reviews(2021)10.1124/pharmrev.120.000269

N/A

1.6DataRank · unranked

74 citations

Francesco Raimondi, Nadia Arang, Friedrich W. Herberg, Susan S. Taylor, J. Silvio Gutkind +1 more

Molecular-dynamics simulation methods for macromolecular crystallography

Acta Crystallographica Section D Structural Biology(2022)10.1107/s2059798322011871

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0.500DataRank · unranked

27 citations

Phillip C. Aoto, Lily Vu, Alexander M. Wolff, David L. Mobley, James S. Fraser +3 more

Role of the αC-β4 loop in protein kinase structure and dynamics

eLife(2023)10.7554/elife.91980

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0.256DataRank · unranked

4 citations

Nisha Amarnath Jonniya, Sophia P. Hirakis, Cristina Olivieri, Gianluigi Veglia, Alexandr P. Kornev +2 more

Hypothesis: Unifying model of domain architecture for conventional and novel protein kinase C isozymes

IUBMB Life(2020)10.1002/iub.2401

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0DataRank · unranked

16 citations

Susan S. Taylor, Alexandra C. Newton, Alexandr P. Kornev, Alexander C. Jones

Allosteric pluripotency as revealed by protein kinase A

Science Advances(2020)10.1126/sciadv.abb1250

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0DataRank · unranked

42 citations

Madoka Akimoto, Bryan VanSchouwen, Tomas S. Lazarou, Susan S. Taylor, Giuseppe Melacini +1 more

Structural analyses of the PKA RIIβ holoenzyme containing the oncogenic DnaJB1-PKAc fusion protein reveal protomer asymmetry and fusion-induced allosteric perturbations in fibrolamellar hepatocellular carcinoma

PLoS Biology(2020)10.1371/journal.pbio.3001018

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0DataRank · unranked

24 citations

Phillip C. Aoto, Jui‐Hung Weng, Cole Nielsen, Jennifer N. Cash, James E. Hall +5 more

Conformation and Dynamics of the Kinase Domain Drive Subcellular Location and Activation of LRRK2.

Research Square(2020)10.21203/rs.3.rs-59611/v1

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0DataRank · unranked

0 citations

Jui‐Hung Weng, Phillip C. Aoto, Daniela Boassa, Steven Silletti, Sebastian Mathea +7 more

mTORC2 controls the activity of PKC and Akt by phosphorylating a conserved TOR interaction motif

Science Signaling(2021)10.1126/scisignal.abe4509

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0DataRank · unranked

113 citations

Gema Lordén, Jacob M. Wozniak, Andreas Feichtner, Wayland Yeung, Alexandr P. Kornev +13 more

From structure to the dynamic regulation of a molecular switch: A journey over 3 decades

Journal of Biological Chemistry(2021)10.1016/j.jbc.2021.100746

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0DataRank · unranked

106 citations

Jian Wu, Jessica Bruystens, Jason C. Del Rio, Tsan‐Wen Lu, Alexandr P. Kornev +2 more

Conformation and dynamics of the kinase domain drive subcellular location and activation of LRRK2

Proceedings of the National Academy of Sciences(2021)10.1073/pnas.2100844118

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0DataRank · unranked

77 citations

Jui‐Hung Weng, Phillip C. Aoto, Daniela Boassa, Sebastian Mathea, Steve Silletti +8 more

Defective internal allosteric network imparts dysfunctional ATP/substrate-binding cooperativity in oncogenic chimera of protein kinase A

Communications Biology(2021)10.1038/s42003-021-01819-6

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0DataRank · unranked

30 citations

Caitlin Walker, Adak Karamafrooz, Yingjie Wang, V. S. Manu, Fernando Porcelli +7 more

Is Disrupted Nucleotide-Substrate Cooperativity a Common Trait for Cushing's Syndrome Driving Mutations of Protein Kinase A?

Journal of Molecular Biology(2021)10.1016/j.jmb.2021.167123

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0DataRank · unranked

25 citations

Yingjie Wang, Cristina Olivieri, Manu Veliparambil Subrahmanian, Jiali Gao, David Bernlohr +4 more

Protein Kinase A in Human Retina: Differential Localization of Cβ, Cα, RIIα, and RIIβ in Photoreceptors Highlights Non-redundancy of Protein Kinase A Subunits

Frontiers in Molecular Neuroscience(2021)10.3389/fnmol.2021.782041

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0DataRank · unranked

9 citations

Yuliang Ma, Zbigniew Mikulski, Qianlan Xu, Ronit Ilouz, Susan S. Taylor +2 more

Subcellular localization of PKA catalytic subunits provides a basis for their distinct functions in the retina

bioRxiv (Cold Spring Harbor Laboratory)(2021)10.1101/2021.05.17.444584

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0DataRank · unranked

1 citations

Yuliang Ma, Zbigniew Mikulski, Qianlan Xu, Ronit Ilouz, Susan S. Taylor +2 more

Two helices control the dynamic crosstalk between the catalytic domains of LRRK2

bioRxiv (Cold Spring Harbor Laboratory)(2021)10.1101/2021.09.29.462278

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0DataRank · unranked

1 citations

Phillip C. Aoto, Robin Lorenz, Jian Wu, Sven H. Schmidt, Jascha T. Manschwetus +6 more

Protein Kinase Cγ Mutations Drive Spinocerebellar Ataxia Type 14 by Impairing Autoinhibition

bioRxiv (Cold Spring Harbor Laboratory)(2021)10.1101/2021.06.24.449810

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0DataRank · unranked

0 citations

Timothy R. Baffi, Alexandr P. Kornev, Maya T. Kunkel, Mario Malfavon, Donghui Chen +9 more

Integrated Regulation of PKA by Fast and Slow Neurotransmission in the Nucleus Accumbens Controls Plasticity and Stress Responses

bioRxiv (Cold Spring Harbor Laboratory)(2021)10.1101/2021.09.29.462408

N/A

0DataRank · unranked

0 citations

Adán Hernández, David R. Benavides, Wei Li, Chunfeng Tan, Florian Plattner +5 more

A PKA inhibitor motif within SMOOTHENED controls Hedgehog signal transduction

Nature Structural & Molecular Biology(2022)10.1038/s41594-022-00838-z

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0DataRank · unranked

68 citations

Corvin D. Arveseth, Jessica Bruystens, Daniela Bertinetti, Isaac Nelson, Cristina Olivieri +14 more

ATP-competitive inhibitors modulate the substrate binding cooperativity of a kinase by altering its conformational entropy

Science Advances(2022)10.1126/sciadv.abo0696

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0DataRank · unranked

58 citations

Geoffrey Li, Yingjie Wang, Manu Veliparambil Subrahmanian, Caitlin Walker, Jonggul Kim +7 more

LRRK2 dynamics analysis identifies allosteric control of the crosstalk between its catalytic domains

PLoS Biology(2022)10.1371/journal.pbio.3001427

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0DataRank · unranked

27 citations

Phillip C. Aoto, Robin Lorenz, Jian Wu, Sven H. Schmidt, Jascha T. Manschwetus +8 more

A non-catalytic herpesviral protein reconfigures ERK-RSK signaling by targeting kinase docking systems in the host

Nature Communications(2022)10.1038/s41467-022-28109-x

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0DataRank · unranked

26 citations

Péter Sok, Fridolin Groß, Krisztián Albert, Evan Kobori, Ádám Póti +8 more

Integrated regulation of PKA by fast and slow neurotransmission in the nucleus accumbens controls plasticity and stress responses

Journal of Biological Chemistry(2022)10.1016/j.jbc.2022.102245

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0DataRank · unranked

1 citations

Adán Hernández, David R. Benavides, Wei Li, Chunfeng Tan, Alan Umfress +6 more

Molecular-Dynamics Simulation Methods for Macromolecular Crystallography

bioRxiv (Cold Spring Harbor Laboratory)(2022)10.1101/2022.04.04.486986

N/A

0DataRank · unranked

4 citations

Phillip C. Aoto, Lily Vu, Alexander M. Wolff, David L. Mobley, James S. Fraser +3 more

Capturing differences in the regulation of LRRK2 dynamics and conformational states by small molecule kinase inhibitors

bioRxiv (Cold Spring Harbor Laboratory)(2022)10.1101/2022.10.24.513618

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0DataRank · unranked

1 citations

Wen Ma, Jian Wu, Steve Silletti, J. Andrew McCammon, Susan S. Taylor +1 more

Unconventional GPCR‐PKA Signaling in the Hedgehog Pathway

The FASEB Journal(2022)10.1096/fasebj.2022.36.s1.r2978

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0DataRank · unranked

0 citations

John T. Happ, Corvin D. Arveseth, Jessica Bruystens, Daniela Bertinetti, Isaac Nelson +12 more

Non‐canonical Recruitment of PKA Catalytic Subunits to RIα‐driven Biomolecular Condensates

The FASEB Journal(2022)10.1096/fasebj.2022.36.s1.r2418

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0DataRank · unranked

0 citations

Jason Z. Zhang, Emily H. Pool, Jaclyn L.C. Choi, Susan S. Taylor, Xin Zhuo +2 more

The Forgotten PKAs: New Insights Revealed by the First Crystal Structure of a PKA C Beta Splice Variant, Cβ4ab

The FASEB Journal(2022)10.1096/fasebj.2022.36.s1.r6147

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0DataRank · unranked

0 citations

Jian Wu, Maximilian Wallbott, Daniela Bertinetti, Friedrich W. Herberg, Susan S. Taylor +1 more

Capturing Differences in the Regulation of LRRK2 Dynamics and Conformational States by Small Molecule Kinase Inhibitors

ACS Chemical Biology(2023)10.1021/acschembio.2c00868

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0DataRank · unranked

20 citations

Wen Ma, Jian Wu, Pallavi Kaila Sharma, Steve Silletti, J. Andrew McCammon +2 more

Edmond Fischer's kinase legacy: History of the protein kinase inhibitor and protein kinase A

IUBMB Life(2023)10.1002/iub.2714

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0DataRank · unranked

16 citations

Friedrich W. Herberg, Gianluigi Veglia, Jian Wu, Susan S. Taylor

Capturing the domain crosstalk in full length LRRK2 and LRRK2RCKW

Biochemical Journal(2023)10.1042/bcj20230126

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0DataRank · unranked

16 citations

Jui‐Hung Weng, Jian Wu, Daniela Bertinetti, Pallavi Kaila Sharma, Wen Ma +3 more

Gauging Dynamics-driven Allostery Using a New Computational Tool: A CAP Case Study

Journal of Molecular Biology(2023)10.1016/j.jmb.2023.168395

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0DataRank · unranked

7 citations

Jui‐Hung Weng, Rodrigo A. Maillard, Susan S. Taylor, Alexandr P. Kornev

An NMR portrait of functional and dysfunctional allosteric cooperativity in cAMP‐dependent protein kinase A

FEBS Letters(2023)10.1002/1873-3468.14610

N/A

0DataRank · unranked

9 citations

Caitlin Walker, Manu Veliparambil Subrahmanian, Fernando Porcelli, Susan S. Taylor, David Bernlohr +2 more

The αC-β4 loop controls the allosteric cooperativity between nucleotide and substrate in the catalytic subunit of protein kinase A

eLife(2023)10.7554/elife.91506

N/A

0DataRank · unranked

7 citations

Yingjie Wang, Caitlin Walker, Manu Veliparambil Subrahmanian, Kim N. Ha, David Bernlohr +6 more

Single-residue mutation in protein kinase C toggles between cancer and neurodegeneration

Biochemical Journal(2023)10.1042/bcj20220397

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0DataRank · unranked

5 citations

Alexandr P. Kornev, Jui‐Hung Weng, Gerard Manning, Susan S. Taylor, Alexandra C. Newton +1 more

Molecular Determinants and Signaling Effects of PKA RIα Phase Separation

bioRxiv (Cold Spring Harbor Laboratory)(2023)10.1101/2023.12.10.570836

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0DataRank · unranked

8 citations

Emily H. Pool, Jessica Bruystens, Xin‐Fu Zhou, Qingrong Li, Daojia R. Zhou +11 more

Protein Kinase Structure and Dynamics: Role of the αC-β4 Loop

bioRxiv (Cold Spring Harbor Laboratory)(2023)10.1101/2023.08.31.555822

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0DataRank · unranked

5 citations

Nisha Amarnath Jonniya, Sophia P. Hirakis, Cristina Olivieri, Gianluigi Veglia, Alexandr P. Kornev +2 more

Do perineuronal nets stabilize the engram of a synaptic circuit?

bioRxiv (Cold Spring Harbor Laboratory)(2023)10.1101/2023.04.09.536164

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0DataRank · unranked

4 citations

Sakina P. Lemieux, Thomas J. Deerinck, Eric A. Bushong, Brandon H. Toyama, Álex Pérez +9 more

Protein Kinase Structure and Dynamics: Role of the αC-β4 Loop

(2023)10.7554/elife.91980.2

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0DataRank · unranked

2 citations

Nisha Amarnath Jonniya, Sophia P. Hirakis, Cristina Olivieri, Gianluigi Veglia, Alexandr P. Kornev +2 more

Protein Kinase Structure and Dynamics: Role of the αC-β4 Loop

(2023)10.7554/elife.91980.1

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0DataRank · unranked

1 citations

Nisha Amarnath Jonniya, Sophia P. Hirakis, Cristina Olivieri, Gianluigi Veglia, Alexandr P. Kornev +2 more

Single-residue mutation in protein kinase C toggles between cancer and neurodegeneration

bioRxiv (Cold Spring Harbor Laboratory)(2023)10.1101/2023.03.16.532226

N/A

0DataRank · unranked

0 citations

Alexandr P. Kornev, Jui‐Hung Weng, Gerard Manning, Susan S. Taylor, Alexandra C. Newton +1 more

Joint Public Review: Protein Kinase Structure and Dynamics: Role of the αC-β4 Loop

(2023)10.7554/elife.91980.1.sa0

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0DataRank · unranked

0 citations

Nisha A. Jonniya, Sophia P. Hirakis, Cristina Olivieri, Gianluigi Veglia, Alexandr P. Kornev +2 more

Reviewer #1 (Public Review): Protein Kinase Structure and Dynamics: Role of the αC-β4 Loop

(2023)10.7554/elife.91980.2.sa0

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0DataRank · unranked

0 citations

Nisha Amarnath Jonniya, Sophia P. Hirakis, Cristina Olivieri, Gianluigi Veglia, Alexandr P. Kornev +2 more

Author Response: Protein Kinase Structure and Dynamics: Role of the αC-β4 Loop

(2023)10.7554/elife.91980.2.sa2

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0DataRank · unranked

0 citations

Nisha Amarnath Jonniya, Sophia P. Hirakis, Cristina Olivieri, Gianluigi Veglia, Alexandr P. Kornev +2 more

Molecular determinants and signaling effects of PKA RIα phase separation

Molecular Cell(2024)10.1016/j.molcel.2024.03.002

N/A

0DataRank · unranked

31 citations

Emily H. Pool, Jessica Bruystens, Xin Zhou, Qingrong Li, Daojia Zhou +11 more

The αC-β4 loop controls the allosteric cooperativity between nucleotide and substrate in the catalytic subunit of protein kinase A

eLife(2024)10.7554/elife.91506.3

N/A

0DataRank · unranked

6 citations

Yingjie Wang, Caitlin Walker, Manu Veliparambil Subrahmanian, Kim N. Ha, David Bernlohr +6 more

Role of the leucine-rich repeat protein kinase 2 C-terminal tail in domain cross-talk

Biochemical Journal(2024)10.1042/bcj20230477

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0DataRank · unranked

5 citations

Jui‐Hung Weng, Jascha T. Manschwetus, Jian Wu, Wen Ma, Friedrich W. Herberg +2 more

RedOx regulation of LRRK2 kinase activity by active site cysteines

npj Parkinson s Disease(2024)10.1038/s41531-024-00683-5

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0DataRank · unranked

7 citations

Jui‐Hung Weng, Pallavi Kaila Sharma, Viktoria Nolte, Jian Wu, Wen Ma +4 more

How an intrinsically disordered regulatory subunit assembles a PP1:eIF2 complex

Cell Reports(2024)10.1016/j.celrep.2024.114011

N/A

0DataRank · unranked

1 citations

Jian Wu, Susan S. Taylor, Alexander C. Jones

Aberrant phase separation of two PKA RIβ neurological disorder mutants leads to mechanistically distinct signaling deficits

Cell Reports(2025)10.1016/j.celrep.2025.115797

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0DataRank · unranked

7 citations

Alexander G P Glebov-McCloud, Ha Neul Lee, Julia C. Hardy, Valeria Pane, Friedrich W. Herberg +5 more

C-spine mutations of protein kinase C and Akt as a novel generalizable approach to create stable pseudokinases

Journal of Biological Chemistry(2025)10.1016/j.jbc.2025.110921

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0DataRank · unranked

2 citations

Tiffany Kao, Jian Wu, Nileeka Balasuriya, Corina E. Antal, Susan S. Taylor +2 more

An alternative pocket for binding the N‐degrons by the UBR1 and UBR2 ubiquitin E3 ligases

Protein Science(2025)10.1002/pro.70248

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0DataRank · unranked

1 citations

D. Chen, Tianchen Ren, N. Thomas, Jian Wu, Banumathi Sankaran +4 more

Allosteric binding cooperativity in kinases signaling, signalopathies, and drug development

Current Opinion in Structural Biology(2025)10.1016/j.sbi.2025.103169

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0DataRank · unranked

1 citations

Jian Wu, Susan S. Taylor, Gianluigi Veglia, Cristina Olivieri

N3A motifs in RIβ mediate allosteric crosstalk between cAMP and ATP in PKA activation

Protein Science(2025)10.1002/pro.70332

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0DataRank · unranked

1 citations

Jessica Bruystens, PK Sahoo, José Bubis, Rodrigo A. Maillard, Susan S. Taylor +2 more

Phase Separation of a PKA Regulatory Subunit Controls cAMP Compartmentation and Oncogenic Signaling

Cell(2020)10.1016/j.cell.2020.07.043

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0DataRank · unranked

332 citations

Tsan-Wen Lu, Lucas M. Stolerman, Brian Tenner, Jin-fan Zhang, Martin Falcke +5 more

Functional divergence of protein kinase A regulatory subunit Iβ variants: the importance of N3A motifs in PKA regulation

FEBS Journal(2025)10.1111/febs.70358

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0DataRank · unranked

0 citations

Jui‐Hung Weng, Valeria Pane, Yuliang Ma, Jian Wu, Susan S. Taylor +2 more

The In Situ Structure of Parkinson’s Disease-Linked LRRK2

Cell(2020)10.1016/j.cell.2020.08.004

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0DataRank · unranked

220 citations

Robert Buschauer, Jan Böhning, Martina Audagnotto, Keren Lasker, Tsan-Wen Lu +4 more

Germline and Mosaic Variants in PRKACA and PRKACB Cause a Multiple Congenital Malformation Syndrome

The American Journal of Human Genetics(2020)10.1016/j.ajhg.2020.09.005

N/A

0DataRank · unranked

54 citations

Phillip C. Aoto, Erik M.F. Machal, Ana Rivera‐Barahona, Patricia Soto‐Bielicka, Daniela Bertinetti +37 more