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Comparison of Metformin PBPK Models Incorporating Placental Transfer to Predict Fetal and Maternal Exposure

CPT Pharmacometrics & Systems Pharmacology(2025)10.1002/psp4.70136Source: DataRank Database

Comparison of Metformin PBPK Models Incorporating Placental Transfer to Predict Fetal and Maternal Exposure is a research paper published in CPT Pharmacometrics & Systems Pharmacology (2025). On theSindex it has a DataRank of 0.

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›Methodology & internals

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Pipeline:MetadataData-paper checkEnrichmentCitation networkScoring

Enrichment:Funding (4 grants)Impact (FWCI 0.00)OA: goldTopics (42)IDs (PubMed, PMC, OpenAlex)

FAIR Checklist

Context only (not used in score)

Findable (1/2)

Has DOI

Accessible (1/2)

Open Access

Interoperable (0/2)

Reusable (0/3)

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Authors (6)

Mattie Hartauer ORCID,Tajhia L. Whigham ORCID,Maïlys De Sousa Mendes ORCID,Kim L. R. Brouwer ORCID,Mary F. Hébert ORCID

Live enrichment

PubMed:41289433 PMC:PMC12823317 OpenAlex:https://openalex.org/W4416663804

NICHD NIH HHS

Grant: U10 HD047892

NICHD NIH HHS

Grant: UC2 HD113039

NIGMS NIH HHS

Grant: R35 GM122576

NICHD NIH HHS

Grant: R01 HD112282

FWCI

0.00

Citation Percentile

0.4%

goldLicense: cc-by-nc

journalhttps://onlinelibrary.wiley.com/doi/pdfdirect/10.1002/psp4.70136

publisherhttps://onlinelibrary.wiley.com/doi/pdfdirect/10.1002/psp4.70136

publisherhttps://ascpt.onlinelibrary.wiley.com/doi/pdf/10.1002/psp4.70136

publisherhttps://ascpt.onlinelibrary.wiley.com/doi/full-xml/10.1002/psp4.70136

journalhttps://doi.org/10.1002/psp4.70136

Fields of Study

Pregnancy and preeclampsia studiesPregnancy and Medication ImpactGestational Diabetes Research and ManagementHumansMetforminFemalePregnancyPlacentaModels, BiologicalMaternal-Fetal ExchangeHypoglycemic AgentsDiabetes, GestationalAdultFetal BloodMaternal ExposureBiological TransportFetus

MeSH Terms

AdultBiological TransportFemaleFetal BloodFetusHumansHypoglycemic AgentsMaternal-Fetal ExchangeMetforminModels, BiologicalPlacentaPregnancyDiabetes, GestationalMaternal Exposure

Keywords

MetforminPhysiologically based pharmacokinetic modellingFetusPercentilePopulationPharmacokineticsPlacentaEx vivoPregnancyDrug TransportMathematical Modeling