Pilot corpus: NIH-funded biomedical datasets. Any DOI can be scored on demand — network effects sharpen as coverage grows.

Abnormal SCID Newborn Screening and Spontaneous Recovery Associated with a Novel Haploinsufficiency IKZF1 Mutation

Journal of Clinical Immunology(2021)10.1007/s10875-021-01035-1Source: DataRank Database

Abnormal SCID Newborn Screening and Spontaneous Recovery Associated with a Novel Haploinsufficiency IKZF1 Mutation is a research paper published in Journal of Clinical Immunology (2021). On theSindex it has a DataRank of 0.505. It has been cited 8 times, with 6 citing works in its 1-hop citation network.

N/A

0.505DataRank · unranked

Scored on demand from live citation data

Deposits data Open Access8 citations · 6 citing works in its network

Download PDF

Cite:

Linked data & code

refsnp nct

Data availability

Repositories this paper deposited data in (declared in PubMed).

ClinicalTrials.govNCT03385876

DataRank reads this dataset's downstream impact straight off the citation graph — no black box, no proprietary weighting. How is this computed?

›Methodology & internals

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Pipeline:MetadataData-paper checkEnrichmentCitation networkScoring

Enrichment:Funding (5 grants)Impact (FWCI 1.33)OA: greenTopics (56)IDs (PubMed, PMC, OpenAlex)Annotations (2)SDGs (1)

FAIR Checklist

Context only (not used in score)

Findable (1/2)

Has DOI

Accessible (1/2)

Open Access

Interoperable (0/2)

Reusable (0/3)

FAIR checklist signals are shown for context only and do not affect DataRank scoring.

Run a calibrated FAIR evaluation for this paper →

We only score data papers we can read in full — never from an abstract alone.

DataRank Breakdown

Base Score 65%Citation Network 35%

Base Score Contribution

0.330

From this paper's citation signal

Citation Network Contribution

0.175

From 5 citing papers with measurable signal

Learn more about DataRank methodology →

Top 5 citers driving the network score

Ranked by each citer's contribution to N(p) — log1p(C_q) divided by its reference count — out of 6 citers.

Case report: IKZF1-related early-onset CID is expected to be missed in TREC-based SCID screening but can be identified by determination of KREC levels
Frontiers in Immunology20235 citations17 referencesContributes 0.105
Inborn errors of IKAROS and AIOLOS
Current Opinion in Immunology202121 citations67 referencesContributes 0.046
Common Variable Immunodeficiency: More Pathways than Roads to Rome
Annual Review of Pathology Mechanisms of Disease202268 citations171 referencesContributes 0.025
Nature and nurture: understanding phenotypic variation in inborn errors of immunity
Frontiers in Cellular and Infection Microbiology202311 citations166 referencesContributes 0.015
Screening Newborns for Low T Cell Receptor Excision Circles (TRECs) Fails to Detect Immunodeficiency, Centromeric Instability, and Facial Anomalies Syndrome
The Journal of Allergy and Clinical Immunology In Practice20234 citations108 referencesContributes 0.015

Authors (7)

Nicholas J. Gloude ORCID,David Dimmock ORCID,Mari Tokita,Meredith S. Wright,Sergio D. Rosenzweig ORCID

Live enrichment

PubMed:33855675 PMC:PMC11002654 OpenAlex:https://openalex.org/W3154172030

NIH Clinical Center

Grant: 00-000-000

National Institute of Child Health and Human Development

Grant: U19HD077693

Intramural NIH HHS

Grant: ZIA AI001122

Intramural NIH HHS

Grant: ZIA CL010304

Intramural NIH HHS

Grant: Z99 CL999999

FWCI

1.33

Citation Percentile

0.8%

Citation Trend

2021

2022

2023

2024

2025

greenLicense: https://www.springer.com/tdm

repositoryhttps://www.ncbi.nlm.nih.gov/pmc/articles/11002654

publisherhttps://link.springer.com/content/pdf/10.1007/s10875-021-01035-1.pdf

publisherhttps://link.springer.com/article/10.1007/s10875-021-01035-1/fulltext.html

journalhttps://doi.org/10.1007/s10875-021-01035-1

Fields of Study

Acute Lymphoblastic Leukemia researchImmunodeficiency and Autoimmune DisordersBlood disorders and treatmentsB-LymphocytesCommon Variable ImmunodeficiencyDNAHEK293 CellsHaploinsufficiencyHumansIkaros Transcription FactorInfant, NewbornMutationNeonatal ScreeningPrimary Immunodeficiency DiseasesSevere Combined ImmunodeficiencyT-Lymphocytes

MeSH Terms

Primary Immunodeficiency DiseasesB-LymphocytesDNAHumansInfant, NewbornMutationT-LymphocytesNeonatal ScreeningSevere Combined ImmunodeficiencyCommon Variable ImmunodeficiencyIkaros Transcription FactorHEK293 CellsHaploinsufficiency

Keywords

HaploinsufficiencySevere combined immunodeficiencyMutationBiologyImmunodeficiencyCommon variable immunodeficiencyPrimary immunodeficiencyGeneticsZinc fingerMutantNonsense mutationImmunologyTranscription factorCancer researchMedicinePhenotypeAntibodyImmune systemGeneMissense mutationT cellsNBSB cellsLymphopeniaCidTrecCvid

Sustainable Development Goals

SDG 0: Good health and well-being