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Complex Autoinflammatory Syndrome Unveils Fundamental Principles of JAK1 Kinase Transcriptional and Biochemical Function

Immunity(2020)10.1016/j.immuni.2020.07.006Source: DataRank Database

Complex Autoinflammatory Syndrome Unveils Fundamental Principles of JAK1 Kinase Transcriptional and Biochemical Function is a research paper published in Immunity (2020). On theSindex it has a DataRank of 0. It has been cited 132 times.

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Open Access132 citations

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›Methodology & internals

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Pipeline:MetadataData-paper checkEnrichmentCitation networkScoring

Enrichment:Funding (21 grants)Impact (FWCI 5.17)OA: bronzeTopics (101)IDs (PubMed, PMC, OpenAlex)Annotations (2)SDGs (2)

FAIR Checklist

Context only (not used in score)

Findable (1/2)

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Accessible (1/2)

Open Access

Interoperable (0/2)

Reusable (0/3)

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Authors (18)

Jorg J. A. Calis ORCID,Sofija Buta ORCID,Gilad D. Evrony ORCID,J.P. Martin ORCID,Skyler Uhl ORCID

Live enrichment

PubMed:32750333 PMC:PMC7398039 OpenAlex:https://openalex.org/W3046413528

National Institute of Allergy and Infectious Diseases

Grant: R01AI127372

National Institute of Allergy and Infectious Diseases

Grant: R21AI129827

National Institute of Allergy and Infectious Diseases

Grant: R21 AI134366

Philippe Foundation

Grant: 5T32HD075735-07

Interdisciplinary Training in Systems and Developmental Biology and Birth Defects

NIAID NIH HHS

Grant: R01 AI137275

NIDDK NIH HHS

Grant: R03 DK117218

NIAID NIH HHS

Grant: R01 AI148963

NIAID NIH HHS

Grant: R01 AI120989

NICHD NIH HHS

Grant: T32 HD075735

NIH HHS

Grant: DP5 OD012142

National Institutes of Health

Grant: 5R03DK117218-02

Epicutaneous Tolerance Induction with Flagellin Epitopes for the Treatment of Colitis

National Institutes of Health

Grant: 5R01AI137275-02

DETERMINING THE ROLE OF THE REPLICATIVE HELICASE IN HUMAN NK CELL DEVELOPMENT

National Institutes of Health

Grant: 7R01AI120989-11

Genetic, Immunologic and Mechanistic Basis of Human NK Cell Deficiency

National Institutes of Health

Grant: 5R21AI129827-02

ZIKA VIRUS RESISTANCE; HOST DETERMINANTS

National Institutes of Health

Grant: 5DP5OD012142-02

Immune profiling by high throughput sequencing of complete antigen receptors

National Institutes of Health

Grant: 5R01AI127372-05

Human ISG15 and USP18 Deficiencies Underlying Type I Interferonopathies

National Institutes of Health

Grant: 1R21AI134366-01

Interplay between Negative Regulators of Type I Interferon and HIV control

Dutch Research Council (NWO)

March of Dimes Foundation

School of Medicine, CHA University

Fondation Bettencourt Schueller

FWCI

5.17

Citation Percentile

1.0%

Citation Trend

2020

2021

2022

2023

2024

2025

2026

bronzeLicense: Elsevier Non-Commercial

journalhttp://www.cell.com/article/S1074761320303137/pdf

publisherhttp://www.cell.com/article/S1074761320303137/pdf

publisherhttps://api.elsevier.com/content/article/PII:S1074761320303137?httpAccept=text/xml

publisherhttps://api.elsevier.com/content/article/PII:S1074761320303137?httpAccept=text/plain

journalhttps://doi.org/10.1016/j.immuni.2020.07.006

Fields of Study

Cytokine Signaling Pathways and InteractionsIL-33, ST2, and ILC PathwaysSystemic Lupus Erythematosus Research0301 basic medicine0303 health sciences03 medical and health sciencesAdolescentCOVID-19Catalytic DomainCell LineCytokinesFemaleGain of Function MutationGenotypeHEK293 CellsHereditary Autoinflammatory DiseasesHumansJanus Kinase 1MosaicismPiperidinesPrecision MedicinePyrimidinesSignal TransductionSystemic Inflammatory Response Syndrome

MeSH Terms

Gain of Function MutationCOVID-19AdolescentCell LineFemaleGenotypeHumansMosaicismPiperidinesPyrimidinesSignal TransductionCytokinesSystemic Inflammatory Response SyndromeCatalytic DomainJanus Kinase 1Hereditary Autoinflammatory DiseasesPrecision MedicineHEK293 Cells

Keywords

BiologyFunction (biology)KinaseProtein-Serine-Threonine KinasesComputational biologyCancer researchCell biologyGeneticsProtein kinase AMonoallelic ExpressionCytokine SignalingJak-stat SignalingPrecision MedicineJak1Jak InhibitorsInborn Errors Of ImmunityMosaicisMESH: Signal Transduction[SDV]Life Sciences [q-bio]MESH: Catalytic DomainMESH: Janus Kinase 1MESH: GenotypePiperidinesCatalytic DomainMESH: COVID-19MESH: CytokinesMosaicismSystemic Inflammatory Response Syndrome[SDV] Life Sciences [q-bio]MESH: PiperidinesMESH: HEK293 CellsGain of Function Mutation[SDV.IMM]Life Sciences [q-bio]/ImmunologyCytokinesFemaleMESH: MosaicismSignal Transduction570[SDV.IMM] Life Sciences [q-bio]/ImmunologyAdolescentGenotype610MESH: Precision MedicineArticleCell LineHumansMESH: AdolescentMESH: Gain of Function MutationMESH: HumansHereditary Autoinflammatory DiseasesMESH: Systemic Inflammatory Response SyndromeCOVID-19Janus Kinase 1MESH: Cell LineHEK293 CellsPyrimidinesMESH: PyrimidinesMESH: Hereditary Autoinflammatory DiseasesMESH: Female

Sustainable Development Goals

SDG 3: 3. Good healthSDG 0: Good health and well-being