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A multi-omics analysis of human fibroblasts overexpressing an Alu transposon reveals widespread disruptions in aging-associated pathways

GeroScience(2025)10.1007/s11357-025-02033-6Source: DataRank Database

A multi-omics analysis of human fibroblasts overexpressing an Alu transposon reveals widespread disruptions in aging-associated pathways is a research paper published in GeroScience (2025). On theSindex it has a DataRank of 0.

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datarank_citation_only_1hop_v6· scope data_onlyMethodology

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Enrichment:Funding (6 grants)Impact (FWCI 0.00)OA: hybridTopics (25)IDs (PubMed, OpenAlex)

FAIR Checklist

Context only (not used in score)

Findable (1/2)

Has DOI

Accessible (1/2)

Open Access

Interoperable (0/2)

Reusable (0/3)

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Authors (9)

Eyael Tewelde,Christina D. King ORCID,Joanna Bons ORCID,Samah Shah ORCID,Jacob Rose ORCID

Live enrichment

PubMed:41381971 OpenAlex:https://openalex.org/W4417247834

NIA NIH HHS

Grant: T32 AG052374

ODCDC CDC HHS

Grant: S10 OD028654

NIA NIH HHS

Grant: P30 AG068345

NIGMS NIH HHS

Grant: R35 GM142395

National Science Foundation

Grant: DGE-1842487

University of Southern California

FWCI

0.00

Citation Percentile

0.2%

hybridLicense: cc-by

journalhttps://link.springer.com/content/pdf/10.1007/s11357-025-02033-6.pdf

publisherhttps://link.springer.com/content/pdf/10.1007/s11357-025-02033-6.pdf

journalhttps://doi.org/10.1007/s11357-025-02033-6

repositoryhttps://pubmed.ncbi.nlm.nih.gov/41381971

repositoryhttps://pmc.ncbi.nlm.nih.gov/articles/PMC13356197/

Fields of Study

Chromosomal and Genetic VariationsTelomeres, Telomerase, and SenescenceGenomic variations and chromosomal abnormalities

MeSH Terms

MultiomicsAgingCells, CulturedFibroblastsHumansCellular SenescenceAlu ElementsTranscriptome

Keywords

Transposable elementAlu elementExtracellular matrixGenomeHuman genomeFunctional genomicsDownregulation and upregulationCellMitochondrionAgingFibroblastsRetrotransposonsAluMulti-omics