Pilot corpus: NIH-funded biomedical datasets. Any DOI can be scored on demand — network effects sharpen as coverage grows.

Novel pyrazolo[4,3-d]pyrimidine microtubule targeting agents (MTAs): Synthesis, structure–activity relationship, in vitro and in vivo evaluation as antitumor agents

Bioorganic & Medicinal Chemistry Letters(2021)10.1016/j.bmcl.2021.127923Source: DataRank Database

Novel pyrazolo[4,3-d]pyrimidine microtubule targeting agents (MTAs): Synthesis, structure–activity relationship, in vitro and in vivo evaluation as antitumor agents is a research paper published in Bioorganic & Medicinal Chemistry Letters (2021). On theSindex it has a DataRank of 0. It has been cited 24 times.

N/A

0DataRank · unranked

Scored on demand from live citation data

Open Access24 citations

Download PDF

Cite:

Linked data & code

pdb

DataRank reads this dataset's downstream impact straight off the citation graph — no black box, no proprietary weighting. How is this computed?

›Methodology & internals

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Pipeline:MetadataData-paper checkEnrichmentCitation networkScoring

Enrichment:Funding (8 grants)Impact (FWCI 1.47)OA: greenTopics (50)IDs (PubMed, PMC, OpenAlex)Annotations (1)SDGs (2)

FAIR Checklist

Context only (not used in score)

Findable (1/2)

Has DOI

Accessible (1/2)

Open Access

Interoperable (0/2)

Reusable (0/3)

FAIR checklist signals are shown for context only and do not affect DataRank scoring.

Run a calibrated FAIR evaluation for this paper →

We only score data papers we can read in full — never from an abstract alone.

Authors (7)

Tasdique M. Quadery,Ruoli Bai,Lerin R. Luckett‐Chastain ORCID,Ernest Hamel ORCID,Michael A. Ihnat ORCID

Live enrichment

PubMed:33705908 PMC:PMC8113149 OpenAlex:https://openalex.org/W3134211713

NCI NIH HHS

Grant: P30 CA054174

NCI NIH HHS

Grant: HHSN261200800001E

NCI NIH HHS

Grant: R01 CA142868

CCR NIH HHS

Grant: HHSN261200800001C

National Institutes of Health

Grant: 5P30CA054174-16

SAN ANTONIO CANCER INSTITUTE

National Science Foundation

Grant: 0614785

Acquisition of an Upgrade for a 500 MHz NMR Spectrometer

National Institutes of Health

Grant: 5R01CA142868-02

Water Soluble Antimitotics That Circumvent Rumor Resistance

NIH

FWCI

1.47

Citation Percentile

0.8%

Citation Trend

2021

2022

2023

2024

2025

2026

greenLicense: Elsevier TDM

repositoryhttps://www.ncbi.nlm.nih.gov/pmc/articles/8113149

publisherhttps://api.elsevier.com/content/article/PII:S0960894X21001499?httpAccept=text/xml

publisherhttps://api.elsevier.com/content/article/PII:S0960894X21001499?httpAccept=text/plain

journalhttps://doi.org/10.1016/j.bmcl.2021.127923

Fields of Study

Synthesis and biological activityCancer therapeutics and mechanismsSynthesis and Biological Evaluation0301 basic medicine03 medical and health sciences0302 clinical medicine

MeSH Terms

AnimalsAntineoplastic AgentsHumansMicrotubulesModels, MolecularNeoplasms, ExperimentalPyrimidinesStructure-Activity RelationshipMolecular StructureCell Line, TumorTubulin ModulatorsMice

Keywords

ChemistryTubulinPaclitaxelIn vivoMicrotubule polymerizationPyrimidineMicrotubuleStereochemistryIn vitroCell culturePharmacologyBiochemistryCancerBiologyCell biologyStructure–activity RelationshipNuclear Overhauser Effect SpectroscopyColchicine SiteMicrotubule Targeting AgentsPyrazolo[4,3-d]pyrimidineModels, MolecularMolecular StructureAntineoplastic AgentsNeoplasms, ExperimentalMicrotubulesTubulin ModulatorsMiceStructure-Activity RelationshipPyrimidinesCell Line, TumorAnimalsHumans

Sustainable Development Goals

SDG 3: 3. Good healthSDG 0: Good health and well-being

Novel pyrazolo[4,3-d]pyrimidine microtubule targeting agents (MTAs): Synthesis, structure–activity relationship, in vitro and in vivo evaluation as antitumor agents

FAIR Checklist

Authors (7)

Funding (8 grants)

Impact

Open Access

Topics

Annotations (Europe PMC)