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Cytochrome P450 2E1 and its roles in disease

Chemico-Biological Interactions(2020)10.1016/j.cbi.2020.109056Source: DataRank Database

Cytochrome P450 2E1 and its roles in disease is a research paper published in Chemico-Biological Interactions (2020). On theSindex it has a DataRank of 3.1. It has been cited 115 times, with 112 citing works in its 1-hop citation network.

N/A

3.1DataRank · unranked

Scored on demand from live citation data

Open Access115 citations · 112 citing works in its network

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Linked data & code

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DataRank reads this dataset's downstream impact straight off the citation graph — no black box, no proprietary weighting. How is this computed?

›Methodology & internals

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Pipeline:MetadataData-paper checkEnrichmentCitation networkScoring

Enrichment:Funding (4 grants)Impact (FWCI 11.84)OA: greenTopics (49)Linked Datasets (2)DataCite Reuse (2)IDs (PubMed, PMC, OpenAlex)Annotations (1)SDGs (1)

FAIR Checklist

Context only (not used in score)

Findable (2/2)

Has DOI
Indexed in repositories

Accessible (1/2)

Open Access

Interoperable (2/2)

DataCite relations
Linked datasets

Reusable (0/3)

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DataRank Breakdown

Base Score 23%Citation Network 77%

Base Score Contribution

0.713

From this paper's citation signal

Citation Network Contribution

2.4

From 94 citing papers with measurable signal

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Top 5 citers driving the network score

Ranked by each citer's contribution to N(p) — log1p(C_q) divided by its reference count — out of 112 citers.

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Authors (1)

F. Peter Guengerich ORCID

Live enrichment

PubMed:32198084 PMC:PMC7217708 OpenAlex:https://openalex.org/W3011337660

NIGMS NIH HHS

Grant: R01 GM118122

NIAAA NIH HHS

Grant: R13 AA027725

National Institutes of Health

Grant: 5R01GM118122-21

Metabolism of Carcinogens and Drugs by Human P450s

National Institutes of Health

FWCI

11.84

Citation Percentile

1.0%

Citation Trend

2020

2021

2022

2023

2024

2025

2026

greenLicense: Elsevier TDM

repositoryhttps://www.ncbi.nlm.nih.gov/pmc/articles/7217708

publisherhttps://api.elsevier.com/content/article/PII:S0009279719311263?httpAccept=text/xml

publisherhttps://api.elsevier.com/content/article/PII:S0009279719311263?httpAccept=text/plain

journalhttps://doi.org/10.1016/j.cbi.2020.109056

Fields of Study

Pharmacogenetics and Drug MetabolismDrug Transport and Resistance MechanismsAlcohol Consumption and Health Effects0301 basic medicine0303 health sciences03 medical and health sciencesAcetaminophenAnimalsCarcinogensCytochrome P-450 CYP2E1EthanolHumansKineticsMitochondriaNeoplasmsReactive Oxygen Species

MeSH Terms

AcetaminophenEthanolAnimalsCarcinogensHumansKineticsMitochondriaNeoplasmsReactive Oxygen SpeciesCytochrome P-450 CYP2E1

Keywords

CYP2E1Cytochrome P450AcetaminophenChemistryEnzymeBiochemistryCatalasePharmacologyBiologyEthanolSNPNitrosaminesSnvKinetic Isotope EffectsP450 2E1Cytochrome P-450 CYP2E1MitochondriaKineticsNeoplasmsCarcinogensAnimalsHumansReactive Oxygen Species

Sustainable Development Goals

SDG 3: 3. Good health

Additional file 1 of The POR rs10954732 polymorphism decreases susceptibility to hepatocellular carcinoma and hepsin as a prognostic biomarker correlated with immune infiltration based on proteomics

10.6084/m9.figshare.19178986.v1figshare

Additional file 1 of The POR rs10954732 polymorphism decreases susceptibility to hepatocellular carcinoma and hepsin as a prognostic biomarker correlated with immune infiltration based on proteomics

10.6084/m9.figshare.19178986figshare